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All Journal Jurnal EduHealth Aesculapius Medical Journal Warmadewa Minesterium Medical Journal
Ni Wayan Rusni
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Public Health Veterinary

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Effect of Candesartan on Creatinine and Albuminuria in Geriatric Patients with Diabetic Nephropathy Sri Yenny, Luh Gede; Ni Wayan Rusni
Jurnal EduHealth Vol. 16 No. 04 (2025): Jurnal EduHealt, Edition October-December , 2025
Publisher : Sean Institute

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Abstract

Diabetes can cause various chronic complications, one of the most feared being diabetic nephropathy. Diabetic nephropathy is characterized by proteinuria and/or decreased glomerular filtration rate. Diabetic nephropathy is a major cause of chronic kidney disease, which can lead to end-stage renal disease requiring hemodialysis. Candesartan is an angiotensin receptor blocker antihypertensive drug. In addition to lowering blood pressure, candesartan is also thought to decrease renal vascular resistance, resulting in a decrease in microalbuminuria or proteinuria in patients with diabetes mellitus. Diabetic nephropathy increases with age, and geriatric patients have a lower response to therapy than adults. To determine the effect of candesartan on creatinine and albuminuria in geriatric patients with diabetic nephropathy. This was a cross-sectional study of 25 geriatric patients diagnosed with diabetic nephropathy who had been given 16 mg of candesartan as an antihypertensive at the Puri Raharja Hospital Denpasar outpatient clinic. Subjects who met the inclusion and exclusion criteria were recruited using consecutive sampling. The diabetic nephropathy subjects were evaluated for creatinine and proteinuria levels at the time of diagnosis and 3 months after receiving 16 mg of candesartan. All data were obtained from medical records. The study involved 25 patients consisting of 13 men (52%) and 12 women (485%). Subjects aged between 60-82 years with initial creatinine levels of 0.80-2.60 mg/dL, final creatinine levels of 1.395 ± 0.50 SD, initial positive proteinuria levels of 0-2, and final positive creatinine levels of 0-1. Based on the T-test, there was no significant difference between initial and final creatinine levels with a p value = 0.892 (95% CI -0.045-0.051). Based on the Wilcoxon test, there was a significant difference between proteinuria levels before and after candesartan administration with a p value p <0.05. This study did not find a significant decrease in creatinine after candesartan administration. However, candesartan significantly reduced proteinuria in geriatric patients with diabetic nephropathy.
Faktor-Faktor yang Berhubungan Dengan Keluhan Muskuloskeletal Disorders (MSDs) pada Pekerja Pengangkat Ikan di Usaha Dagang Mina Karya Karangasem I Putu Ning Arya Dyana; Ni Wayan Rusni; Ni Made Hegard Sukmawati
Aesculapius Medical Journal Vol 3 No 1 (2023): February
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.3.1.2023.93-100

Abstract

MSDs complaints can reduce worker productivity, increase healthcare costs, slow performance, and miss work due to illness. This study aims to determine the factors associated with MSDs complaints at Usaha Dagang Mina Karya Karangasem. This is an observational analytic study with cross sectional design conducted in March-May 2022. Target population is fish carrier workers at Usaha Dagang Mina Karya Karangasem. Total sample was 30 people with total sampling. Independent variables are age, body composition, work posture, years of service, length of work, and workload while dependent variable is MSDs complaints. Data were collected with questionnaire to determine risk factors, a REBA questionnaire to determine work posture, and a Nordic Body Map questionnaire to determine musculoskeletal complaints. Data were analyzed using Spearman's test with SPSS application. Based on the results of the study, there was a strong relationship between workload and MSDs complaints (r=0.713; p<0.001) and a very strong relationship between work posture and MSDs complaints (r=0.926; p<0.001). No significant relationship was found between age, BMI, years of service, and length of work on MSDs complaints. Business owners should provide education about good work posture to reduce MSDs complaints to workers. The workload in one transport should also be reduced
Hubungan Sikap Kerja dengan Kejadian Low Back Pain (LBP) pada Pegawai Bank X di Kabupaten Gianyar I Made Melvin Risma Putra; Ni Wayan Rusni; Ni Made Hegard Sukmawati
Aesculapius Medical Journal Vol 2 No 2 (2022): Agustus
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/amj.2.2.2022.82 - 90

Abstract

Low Back Pain (LBP) is a serious problem that has become the target of monitoring by the World Health Organization (WHO) as one of the top three problems. Low back pain is caused by several things such as trauma, tissue changes, and the influence of gravity. The purpose of this study was to determine the correlation between work posture and the incidence of low back pain (LBP) in Bank X employees in Gianyar Regency. The method of this study was an analytic observational with cross sectional approach. This study was conducted by total sampling on 35 respondents who involved inclusion and exclusion criteria. Low Back Pain was measured using the Rolland-Morris Disability Questionnaire (RMDQ), while Rapid Entire Body Assessment (REBA) was used to measure the working posture. The data were analyzed with Chi-Square Test using SPSS 26.0. The results were showed as followed: the low, mild, and high risk of working posture, 25.7 %, 34.3 % and 40.0 %, respectively; while the respondent with LBP was 57.1 %; The conclusion could be drawn that there was a correlation between working posture and LBP. It was recommended that the workers of the bank especially in the marketing department should be working postures in ergonomics approach.
Pelatihan Interpretasi Elektrokardiogram bagi Tenaga Kesehatan di Puskesmas III Denpasar Selatan Komang Trisna Sumadewi; Ni Wayan Rusni; Tanjung Subrata; Luh Gede Sri Yenny
Warmadewa Minesterium Medical Journal Vol. 3 No. 1 (2024): Januari 2024
Publisher : Warmadewa University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmmj.3.1.2024.21-27

Abstract

Henti jantung merupakan salah satu penyebab kematian utama didunia. Sekitar 85% penderita penyakit kardiovaskuler meninggal akibat henti jantung. Aritmia juga berkontribusi dalam menyebabkan kematian hingga mencapai 50% kasus. Prevalensi aritmia di Indonesia meningkat seiring dengan bertambahnya usia yaitu 70% pada usia 65-85 tahun dan 8% pada usia diatas 85 tahun. Penderita gangguan kardiovaskuler umumnya mendapatkan pemeriksaan elektrokardiogram (EKG) untuk menegakkan diagnosis. Tenaga medis harus mampu menginterpretasikan hasil rekaman EKG, meliputi gangguan konduksi, aritmia, dan gangguan miokard sehingga dapat mengetahui mengidentifikasi kegawatdaruratan di bidang kardiovaskuler. Wawancara bersama tenaga kesehatan di Puskesmas III Denpasar Selatan menemukan fasilitas untuk mendeteksi penyakit jantung masih terbatas. Mesin EKG di Puskesmas tergolong cukup jarang digunakan sehingga keterampilan dalam menggunakan EKG dan menginterpretasikannya mengalami penurunan. Tujuan dari program kemitraan ini adalah untuk meningkatkan pengetahuan tenaga kesehatan mengenai kegawatdaruratan kardiovaskuler serta meningkatkan keterampilan tenaga kesehatan di lingkungan Puskesmas III Denpasar Selatan mengenai penggunaan EKG serta interpretasinya. Mengacu pada permasalahan tersebut, maka dilaksanakan kegiatan pengabdian dengan memberikan edukasi mengenai kegawatdaruratan di bidang kardiovaskuler, melatih tenaga kesehatan dalam menggunakan mesin EKG serta menginterpretasikan hasil rekaman EKG. Program ini diharapkan dapat membantu tenaga kesehatan di lingkungan Puskesmas III Denpasar Selatan menambah wawasan mengenai penyakit kardiovaskuler serta menurunkan angka kematian akibat penyakit kardiovaskuler. Program kemitraan ini dilaksanakan di ruang pertemuan Puskesmas III Denpasar Selatan dengan kehadiran peserta sebanyak 100%. Berdasarkan nilai pretest dan postest didapatkan peningkatan pengetahuan peserta mengenai penyakit kardiovaskuler (36,9%). Keterampilan mitra dalam menggunakan mesin EKG dan menginterpretasikannya juga meningkat dari observasi yang dilakukan oleh tim pengabdian.
Co-Authors Hegard Sukmawati, Ni Made I Kadek Indra Partawiguna I Made Melvin Risma Putra I Made Melvin Risma Putra I Putu Ning Arya Dyana I Putu Ning Arya Dyana Komang Trisna Sumadewi Luh Gede Pradnyawati Luh Gede Sri Yenny Tanjung Subrata