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Triani Kurniawati, Triani
Faculty of pharmacy, Universitas Gadjah Mada. Yogyakarta, Indonesia
Aerospace Engineering Agriculture, Biological Sciences & Forestry Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Immunology & microbiology Medicine & Pharmacology Public Health

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Analisis Penggunaan Antibiotika Pada Pasien Demam Typoid Rawat Inap Di Rumah Sakit Daerah Gunung Jati Cirebon Kurniawati, Triani; Khoeriyah, Khoeriyah
Syntax Idea Vol 2 No 7 (2020): Syntax Idea
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-idea.v2i7.453

Abstract

Demam typoid adalah penyakit infeksi saluran pencernaan yang disebabkan oleh bakteri Salmonella Typhi. Penyakit ini merupakan salah satu penyakit yang sering terjadi, khususnya di negara berkembang. Dalam proses pengobatan penyakit demam typoid dibutuhkan antibiotika. Penggunaan antibiotika yang tidak tepat dapat meningkatkan resiko kejadian efek samping dan resistensi antibiotika. Tujuan Penelitian ini adalah mengetahui pola penggunaan antibiotika dan menganalisis rasionalitas penggunaan antibiotika pada pasien demam typoid rawat inap di Rumah Sakit Daerah Gunung Jati Cirebon periode 2018. Tinjauan Pustaka Penggunaan antibiotika disini di batasi pada tepat diagnosa, tepat indikasi, tepat obat dan tepat dosis. Penelitian ini merupakan penelitian non eksperimental yang bersifat retrospektif. Data yang diambil berasal dari rekam medik pasien demam typoid 49 pasien. Hasil penelitian menunjukan antibiotika yang sering digunakan adalah golongan sepalosporin, yaitu ceftriaxon sebanyak 55%. Dan untuk rasionalitas pengobatan adalah tepat diagnosa 100%, tepat indikasi 100% tepat obat 100% dan tepat dosis 84%.
Kualitas mikrobiologi basis pelembab dari lemak daging Sapi metode low temperature dan bouble boiling berdasarkan angka lempeng total (ALT) Kurniawati, Triani; Luviriani, Eva; Rahasasti, Indri Dwi; Calyptranti, Rosellynia; Shafly, Alman
Borobudur Pharmacy Review Vol 5 No 1 (2025): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i1.13560

Abstract

Dry skin is a problem that bothers many people. One of the causes of dry skin is skin dehydration, which can be overcome by using moisturizing cosmetics. Vaseline is a moisturizer commonly used by the public because it does not cause allergies and has good moisturizing capabilities. However, it is derived from non-renewable petroleum, necessitating alternatives. Animal fats can be used as cosmetic moisturizers and are considered safer than chemical substances like zinc oxide. According to BPOM, cosmetic products must pass safety tests such as microbial contamination, heavy metal contamination, and chemical contamination tests. Beef fat contains water and fatty acids that can create a suitable medium for microbial growth. However, temperature and water content affect microbial growth, necessitating further research on the microbiological quality of beef fat using low temperature and double boiling methods. This study aims to determine the microbiological quality of beef fat moisturizer bases using low temperature and double boiling methods through Total Plate Count (TPC) testing. This research is a pre-experimental study with a one-shot case study design. The results show that the TPC values of beef fat using low temperature and double boiling methods are each 1 x 10^4 CFU/g. This indicates that the TPC values of beef fat using low temperature and double boiling methods do not meet BPOM criteria, which is < 500 CFU/g. Keywords: Moisturizer; Beef Tallow; Low Temperature; Double Boiling; Total Plate Count.
Evaluation of antioxidant activity of face mask combination formula rice (Oryza sativa L.) and jicama (Pachyrhizus erosus L.) Kurniawati, Triani; Jehan, Nabila Nauli; Rahasasti, Indri Dwi; Jumaroh, Jumaroh
Borobudur Pharmacy Review Vol 5 No 2 (2025): August-Dec
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/bphr.v5i2.15223

Abstract

Masks are traditional cosmetic products that contain minerals, vitamins, and proteins, useful for cleaning, brightening, tightening, moisturizing, and preventing premature aging of the skin. This study aims to evaluate the preparation of a combination of rice and yam bean mask through preparation evaluation tests, specific and non-specific standardization, and antioxidant activity tests. The method used was experimental with purposive sampling and antioxidant activity testing using UV-Vis spectrophotometry. Phytochemical results showed that rice contains alkaloids, while yam bean contains alkaloids, tannins, and phenols. All formulations passed the preparation evaluation test and non-specific standards according to the Indonesian Pharmacopoeia Edition VI. The IC₅₀ values ​​of antioxidant activity for the five formulations were 41.15; 25.06; 29.11; 24.27; and 35.58 µg/mL, respectively. The results of One-Way ANOVA showed no significant difference between formulations (p ≥ 0.05).
Co-Authors Indri Dwi Rahasasti Jehan, Nabila Nauli Jumaroh, Jumaroh Khoeriyah, Khoeriyah Luviriani, Eva Rosellynia Calyptranti Shafly, Alman