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<![CDATA[PENGUKURAN TEKANAN DARAH PADA PASIEN GAGAL JANTUNG KONGESTIF DI INSTALASI RAWAT INAP RUMAH SAKIT ST. ELISABETH SEMARANG ]]>
<![CDATA[Rukminingsih, Fef]]>;
<![CDATA[Susanto, Theresia Carolina]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 2 No 1 (2020): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v2i1.64
<![CDATA[Congestive heart failure (CHF) is one of the top 10 diseases in the Inpatient of. St. Elisabeth Hospital Semarang. The main cause of CHF is hypertension. CHF patients receive antihypertensive therapy to control their blood pressure. This study aims to determine the decrease in blood pressure of CHF patients and the suitability of blood pressure of CHF patients with their treatment targets according to the Eighth Joint National Committee (JNC VIII) at the Inpatient Installation of St. Elisabeth Hospital Semarang. This research is an observational descriptive study, using retrospective data. Data was taken from medical records of CHF patients in inpatients who received antihypertensive therapy for the period October - December 2017, 40 years or older, with or without concomitant diseases. Based on the results of tracing of medical records it is known that the number of CHF patients who met the inclusion criteria was 60 people, consisting of 30 male patients and 30 female patients. A total of 35 patients (58.33%) were aged over 60 years. A total of 19 patients had concomitant diabetes mellitus type 2 and / or chronic kidney failure. A total of 51 patients (85%) during hospitalization experienced an average reduction in systolic BP of 21.65 mmHg and as many as 37 patients (61.67%) experienced an average reduction in diastolic BP of 13.38 mmHg. The suitability of the patient's blood pressure when leaving the hospital with the target blood pressure according to JNC VIII is 81.67%. Thus the progression of cardiac deterioration in most CHF patients can be inhibited.]]>
<![CDATA[EVALUASI PERESEPAN PADA PASIEN GERIATRI DI KLINIK PENYAKIT DALAM INSTALASI RAWAT JALAN RSUD K.R.M.T WONGSONEGORO SEMARANG ]]>
<![CDATA[Mulyani, Tri]]>;
<![CDATA[Rukminingsih, Fef]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 2 No 2 (2020): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v2i2.82
<![CDATA[The medical problems encountered in geriatric patients cause the prescribing to be susceptible to polypharmacy so that the possibility of creating Drug Related Problems (DRPs) is likely. Beers Criteria is one method to avoid the occurrence of DRPs. This study aims to evaluate prescribing of geriatric patients based on the Beers Criteria 2015 at the internal medicine clinic in the outpatient installation of K.R.M.T Wongsonegoro Hospital Semarang. This research was an descriptive observational study using retrospective data from geriatric patients' medical records at the internal medicine clinic in the outpatient installation of K.R.M.T Wongsonegoro Hospital Semarang in the period October - December 2017. A total of 300 medical records were taken at simple random as samples. Data for each patient were only taken once during the study period. The patient is a national health insurance participant and is ≥60 years old. The data obtained was then identified using Beers Criteria 2015. Based on the prescription of 300 geriatric patients in the internal medicine clinic in Wongsonegoro Hospital Semarang, it is known that 88,33% patients received prescription included in Beers Criteria 2015. The five medicine most prescribed are Na diclofenac, omeprazole, digoxin, ranitidine, and diazepam. Medications included in Beers Criteria are medicine that should not be given to geriatric patients so that caution is needed in the use of these medicine.]]>
<![CDATA[ANALISIS PENGGUNAAN ANTIBIOTIK PADA PASIEN ANAK DI RUANG THERESIA RUMAH SAKIT ST. ELISABETH SEMARANG DENGAN METODE ATC/DDD ]]>
<![CDATA[Rukminingsih, Fef]]>;
<![CDATA[Apriliyani, Apriliyani]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 1 (2021): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i1.110
<![CDATA[The high incidence of infectious diseases causes the use of antibiotics to increase. Inappropriate use of antibiotics will lead to resistance. Infectious diseases are included in the top 10 diseases in pediatric patients at St. Elisabeth Hospital.Semarang. This study aims to evaluate the use of antibiotics in pediatric patients in the Theresia ward of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. Data were taken from medical records of pediatric patients in the Theresia ward at St. Elisabeth Hospital Semarang, aged 6 months - 14 years, the use of antibiotic therapy during the period October - December 2019. The data obtained were analyzed by calculating the quantity of antibiotic use using the Anatomical Therapeutic Chemical (ATC) and Defined Daily Dose (DDD)) / 100 patient-days methods. Based on the results of tracing medical record data, it was found that the number of pediatric patients in the Theresia room at St. Elisabeth Semarang for the period October - December 2019 is 385. The number of patients who received a single antibiotic was 162. The total value of DDD / 100 patient-days in the Theresia ward of St. Elisabeth Hospital Semarang for the period October - December 2019 is 18.17 with a total length of stay of 1117 days. The antibiotic with the highest DDD / 100 patient-days was ceftriaxone, namely 15.10. While the antibiotics that enter the DU 90% segment are ceftriaxone and cefotaxime.]]>
<![CDATA[LAJU FILTRASI GLOMERULUS PASIEN DIABETES MELITUS TIPE II DI SALAH SATU RUMAH SAKIT SWASTA DI KABUPATEN DEMAK ]]>
<![CDATA[Rukminingsih, Fef]]>;
<![CDATA[Widiastuti, Mei]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 3 No 3 (2021): Jurnal Riset Kefarmasin Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v3i3.179
<![CDATA[Diabetes Mellitus (DM) Type II is a group of metabolic diseases with hyperglycemia characteristics. The use of oral hypoglycemic drugs (OHO) lasts for a relatively long time. Most of the OHO is excreted through the kidneys. This study aims to determine the Glomerulus Filtration Rate (GFR) of type 2 DM patients who use OHO at the "X" Hospital, District of Demak. This study is an observational descriptive study using retrospective data obtained from medical record data (RM) of outpatient JKN participants with type 2 DM for the period October-December 2020. Inclusion criteria were patients who received OHO for at least one year with or without comorbidities, aged 36-65 years, and had a serum creatinine test. Patients receiving combination therapy with insulin were excluded. LFG is calculated using the Cockroft-Gault formula. From 82 patients, 52 patients (62.2%) were female, 74 patients (90.2%) were more than 45 years old. Patients who consumed OHO for more than 2 years were 47 (57.3%). Patients without comorbidities were 62 (75.7%) people. Patients who experienced a decrease in GFR in the moderate category (stage 3) as many as 24 people (29.3%), a decrease in GFR in the severe category (stage 4) as many as 5 people (6.1%) and 1 person (1.2%) experienced End Stage Renal Disease.]]>
<![CDATA[PENGUKURAN TEKANAN DARAH PADA PASIEN PESERTA JKN DENGAN PENYAKIT JANTUNG ISKEMIK DI INSTALASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG ]]>
<![CDATA[Fef Rukminingsih]]>;
<![CDATA[Nike Kusuma Dewi]]>
<![CDATA[ Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jifi.v3i2.619
<![CDATA[Ischemic heart disease (IHD) is defined as a lack of oxygen and decreased or absent blood flow to the myocardium caused by narrowing of the coronary arteries. Hypertension is a risk factor that plays an important role in IHD. Hypertension therapy in IHD patients aims to prevent death, myocardial infarction. This study aims to evaluate the achievement of blood pressure targets in IHD patients participating in JKN in the outpatient installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. Data obtained from the medical records. The inclusion criteria were JKN participant patients with IHD in the Outpatient Installation of St. Elisabeth Hospital Semarang for the period of October-December 2019 who received antihypertensive, aged 26-65 years, had blood pressure data for two consecutive months. The results were 88 patients, consisting of 64 (72.73%) male patients, 46 (52.27%) patients aged 56-65 years. 57 (64.78%) patients had comorbidities, the most comorbidities were type 2 diabetes. The most widely used antihypertensive agents were beta blockers. A total of 82 (93.18%) patients reached the target blood pressure based on JNC 8. The greater the success in achieving the therapeutic target, the risk of death from IHD will decrease.]]>
<![CDATA[BIAYA MEDIK LANGSUNG PASIEN STROKE NON-HEMORAGIK KELAS PERAWATAN 3 RSUD K.R.M.T WONGSONEGORO SEMARANG ]]>
<![CDATA[Hanik Utaminingrum]]>;
<![CDATA[Fef Rukminingsih]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v5i1.413
<![CDATA[The most common stroke in Indonesia is non-hemorrhagic stroke (SNH), which occurs in 85-87% of all stroke cases. Stroke requires expensive costs because the process of treating stroke patients is done in a long time and routine. SNH patients who go to K.R.M.T Wongsonegoro Hospital Semarang every year increase in number. This study aims to determine the amount of direct medical costs for treatment class 3 SNH patients at K.R.M.T Wongsonegoro Hospital Semarang and their compliance with Indonesian Case Based Groups (INA-CBG) rates. This study is a pharmacoeconomic study with a hospital perspective on direct medical costs using retrospective data for the October-December 2018 period. The object of this study is the medical record and billing data from the Hospital Information and Management System SNH patients participating in the National Health Insurance treated in treatment class 3. Based on the results of medical record tracking and billing data for SNH patients, 64 patients were known. The number of female patients was 41 people (64.06%). Most of the patients (93.75%) were over 45 years old. A total of 27 patients included in the category of mild SNH and 37 patients in the category of moderate SNH. The average direct medical cost for SNH patients in the mild category is IDR 3,005,019 ± 1,010,931, - and the compliance with INA-CBG’s tariff was 92.59%. The average direct medical cost for SNH patients in the moderate category is IDR 3,602,846 ± 1,259,001 and the compliance with INA-CBG rates of 94.59%.]]>
<![CDATA[PENGGUNAAN INSULIN PADA PASIEN DIABETES MELITUS TIPE 2 PESERTA JKN DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG ]]>
<![CDATA[Fef Rukminingsih]]>;
<![CDATA[Valentina Catur Nova]]>
<![CDATA[ Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS ]]>
Publisher : <![CDATA[Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin ]]>
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DOI: 10.36387/jiis.v6i1.611
<![CDATA[Diabetes mellitus (DM) type 2 is a chronic and progressive clinical syndrome, characterized by polyuria, polydipsi and polyphagy accompanied by increased blood glucose or hyperglycemia. Management of type 2 diabetes mellitus in patients with HbA1C values > 9% is by administering insulin or a combination of insulin with oral hypoglycemic agents. This study aims to determine the suitability of the type and dose of insulin in type 2 DM patients in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. The data were obtained from the medical records of Universal Health Coverage participant patients with type 2 diabetes mellitus in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang, who only received insulin therapy in January 2020, is 26-65 years old, and has examination results for fasting blood glucose, post prandial blood glucose and HbA1C (examination results for the last 6 months). The results showed that 57 patients consisted of 29 (50.88%) male patients and 28 (49.12%) female patients. A total of 47 (82.46%) patients were more than 45 years old. A total of 38 patients (66.67%) received combination insulin and all patients had HbA1C values> 9%. The suitability of using insulin based on the type of insulin was 68.42% and most of the patients (80.70%) received inappropriate insulin doses.]]>
<![CDATA[EVALUASI TERAPI ADJUVAN DAN KEJADIAN RELAPS PADA PASIEN PREMENOPAUSAL EARLY BREAST CANCER DI RSUP DR. SARDJITO YOGYAKARTA ]]>
<![CDATA[Fef Rukminingsih]]>;
<![CDATA[Tri Murti Andayani]]>;
<![CDATA[Fita Rahmawati]]>;
<![CDATA[Kartika Widayati]]>
<![CDATA[ JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 1 ]]>
Publisher : <![CDATA[Faculty of Pharmacy, Universitas Gadjah Mada ]]>
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DOI: 10.22146/jmpf.364
<![CDATA[Terapi adjuvan pada pasien early breast cancer (EBC) bertujuan untuk meningkatkan disease free survival, menurunkan risiko relaps dan menurunkan angka kematian. Tetapi pada kenyataannya masih sering dijumpai, pasien EBC yang telah mendapat terapi adjuvan mengalami relaps. Kejadian relaps sering dihubungkan dengan meningkatnya risiko kematian tanpa memperhatikan jenis pengobatan. Tujuan penelitian ini adalah mengetahui angka kejadian relaps pada pasien premenopausal EBC yang telah mendapatkan terapi adjuvan di RSUP dr. Sardjito Yogyakarta. Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross sectional study menggunakan data retrospektif yang diperoleh dari data rekam medik pasien premenopausal EBC di Poliklinik Kanker Terpadu “Tulip” RSUP dr. Sardjito Yogyakarta yang telah mengalami tindakan pembedahan pada tahun 2010-2013, bersifat hormon responsif dan HER-2 negatif, mendapatkan terapi adjuvan, perempuan dengan umur 18-60 tahun dan riwayat pemeriksaan sampai bulan Desember 2016. Pasien akan di eksklusi bila mempunyai penyakit penyerta. Dari 30 pasien diketahui sebanyak 46,67% berumur 41-50 tahun, sebanyak 63,33% menunjukkan ekspresi ER-PR positif, sebanyak 93,34% merupakan invasive ductal carcinoma (IDC). Semua pasien mendapatkan terapi adjuvan kemoterapi menggunakan regimen kombinasi dan semua pasien mendapatkan terapi endokrin berupa tamoksifen. Relaps terjadi pada 11 pasien (36,67%) dan kejadian relaps paling banyak adalah metastasis tulang yaitu pada 8 pasien (26,67%).]]>
<![CDATA[EVALUATION ON THE THERAPY APPROPRIATENESS AND ANTIHYPERTENSIVE AGENT SIDE EFFECTS TOWARD TYPE 2 DIABETES MELLITUS WITH CHRONIC KIDNEY DISEASE PATIENTS RECEIVING REGULAR HAEMODIALYSIS AT RSU PKU MUHAMMADIYAH YOGYAKARTA ]]>
<![CDATA[Fef Rukminingsih]]>;
<![CDATA[Djoko Wahyono]]>;
<![CDATA[I Dewa Putu Pramantara]]>
<![CDATA[ JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 1, No 4 ]]>
Publisher : <![CDATA[Faculty of Pharmacy, Universitas Gadjah Mada ]]>
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DOI: 10.22146/jmpf.47
<![CDATA[Antihypertensive selection accuracy determines the achievement of therapy target toward type 2 diabetes mellituswith chronic kidney disease patients who received regular hemodialysis treatment. The use of drugs in a longtimepotentially causes side effects and drug interactions as well.This research employed prospective observation by evaluating the appropriateness of therapy and monitoringdirectly the side effects of antihypertensive agent used toward type 2 diabetes mellitus with chronic kidney diseasepatients who received regular haemodialysis treatment at RSU PKU Muhammadiyah Yogyakarta during February– April 2011.For 42 patients having type 2 diabetes mellitus with chronic kidney disease who received regular haemodialysis treatment, it was found that patients who received appropriate therapy and achieved blood pressure therapy target was none, 4 patients (9.53%) received appropriate therapy yet the blood pressure remained uncontrolled, 2 patients(4.76%) received inappropriate therapy yet achieved controlled blood pressure and 36 patients (85.71%) receivedinappropriate therapy with remained uncontrolled blood pressure. From 42 patients, it was found that there were 11patients (26,20%) were possible and 5 patients (11,90%) were probable suffered from dry cough, 26 patients (61.91%) were possible for suffered from dizziness, 39 patients (92.86%) were possible suffered from headache, 2 patients (4.76%) were potentially suffered from fatigue and 13 patients (30,95%) were possible and 2 patients (4,76%) wereprobable suffered from drowsiness. Keywords: antihypertensive, type 2 diabetes mellitus, haemodialysis]]>
<![CDATA[GAMBARAN FUNGSI HATI PASIEN DIABETES MELITUS TIPE II DI SALAH SATU RUMAH SAKIT SWASTA DI KABUPATEN DEMAK PERIODE OKTOBER-DESEMBER 2020 ]]>
<![CDATA[Megi Pangestuningsih]]>;
<![CDATA[Fef Rukminingsih]]>
<![CDATA[ Jurnal Riset Kefarmasian Indonesia Vol 4 No 2 (2022): Jurnal Riset Kefarmasian Indonesia ]]>
Publisher : <![CDATA[APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia) ]]>
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DOI: 10.33759/jrki.v4i2.262
<![CDATA[Type II DM patients use Oral Antidiabetic Agent (OAA) continuously for a long time. OAA metabolism occurs in the liver. The use of OAA continuously in the long term can cause liver function disorders. The purpose of this study was to describe the liver function of type II DM patients who were treated with OAA in a private hospital in Demak District. This study is an observational descriptive study using retrospective data obtained from medical record documents of outpatients with type II DM for the period October – December 2020. Sampling using purposive sampling technique. The inclusion criteria were outpatients with type II DM, JKN participants who received OAA therapy for at least one year, aged 36 – 65 years old, have AST and ALT laboratory examinations. Patients who received combination therapy with insulin, had a history of impaired liver function were excluded. The results showed that from 62 patients there were 39 female patients (62.9%), the most patients aged 56-65 years were 32 patients (51.61%). The longest duration of use of OAA was 1 year, namely 29 patients (46.77%). The most widely used OAA was a combination of biguanides and sulfonylureas in 36 patients (58.07%). A total of 51 patients (82.25%) did not experience liver function damage and as many as 11 patients (17.75%) showed mild liver function damage with the duration of using OHO for more than 1 year and using OHO combination.]]>
