Article Per Year (5 Year)
p-Index From 2021 - 2026
2.554
P-Index
This Author published in this journals
All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Cendekia Journal of Pharmacy Jurnal Insan Farmasi Indonesia Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JAFP (Jurnal Akademi Farmasi Prayoga) Jurnal Ilmu Multidisplin Journal of Clinical Pharmacy and Pharmaceutical Science Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Fef Rukminingsih
Politeknik Katolik Mangunwijaya, Semarang, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

Published : 17 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 17 Documents
Search

 1   2 
PENGUKURAN TEKANAN DARAH PADA PASIEN PESERTA JKN DENGAN PENYAKIT JANTUNG ISKEMIK DI INSTALASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG Fef Rukminingsih; Nike Kusuma Dewi
Jurnal Insan Farmasi Indonesia Vol 3 No 2 (2020): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v3i2.619

Abstract

Ischemic heart disease (IHD) is defined as a lack of oxygen and decreased or absent blood flow to the myocardium caused by narrowing of the coronary arteries. Hypertension is a risk factor that plays an important role in IHD. Hypertension therapy in IHD patients aims to prevent death, myocardial infarction. This study aims to evaluate the achievement of blood pressure targets in IHD patients participating in JKN in the outpatient installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. Data obtained from the medical records. The inclusion criteria were JKN participant patients with IHD in the Outpatient Installation of St. Elisabeth Hospital Semarang for the period of October-December 2019 who received antihypertensive, aged 26-65 years, had blood pressure data for two consecutive months. The results were 88 patients, consisting of 64 (72.73%) male patients, 46 (52.27%) patients aged 56-65 years. 57 (64.78%) patients had comorbidities, the most comorbidities were type 2 diabetes. The most widely used antihypertensive agents were beta blockers. A total of 82 (93.18%) patients reached the target blood pressure based on JNC 8. The greater the success in achieving the therapeutic target, the risk of death from IHD will decrease.
BIAYA MEDIK LANGSUNG PASIEN STROKE NON-HEMORAGIK KELAS PERAWATAN 3 RSUD K.R.M.T WONGSONEGORO SEMARANG Hanik Utaminingrum; Fef Rukminingsih
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 1 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.256 KB) | DOI: 10.36387/jiis.v5i1.413

Abstract

The most common stroke in Indonesia is non-hemorrhagic stroke (SNH), which occurs in 85-87% of all stroke cases. Stroke requires expensive costs because the process of treating stroke patients is done in a long time and routine. SNH patients who go to K.R.M.T Wongsonegoro Hospital Semarang every year increase in number. This study aims to determine the amount of direct medical costs for treatment class 3 SNH patients at K.R.M.T Wongsonegoro Hospital Semarang and their compliance with Indonesian Case Based Groups (INA-CBG) rates. This study is a pharmacoeconomic study with a hospital perspective on direct medical costs using retrospective data for the October-December 2018 period. The object of this study is the medical record and billing data from the Hospital Information and Management System SNH patients participating in the National Health Insurance treated in treatment class 3. Based on the results of medical record tracking and billing data for SNH patients, 64 patients were known. The number of female patients was 41 people (64.06%). Most of the patients (93.75%) were over 45 years old. A total of 27 patients included in the category of mild SNH and 37 patients in the category of moderate SNH. The average direct medical cost for SNH patients in the mild category is IDR 3,005,019 ± 1,010,931, - and the compliance with INA-CBG’s tariff was 92.59%. The average direct medical cost for SNH patients in the moderate category is IDR 3,602,846 ± 1,259,001 and the compliance with INA-CBG rates of 94.59%.
PENGGUNAAN INSULIN PADA PASIEN DIABETES MELITUS TIPE 2 PESERTA JKN DI INSTALASI FARMASI RAWAT JALAN RUMAH SAKIT ST. ELISABETH SEMARANG Fef Rukminingsih; Valentina Catur Nova
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (169.72 KB) | DOI: 10.36387/jiis.v6i1.611

Abstract

Diabetes mellitus (DM) type 2 is a chronic and progressive clinical syndrome, characterized by polyuria, polydipsi and polyphagy accompanied by increased blood glucose or hyperglycemia. Management of type 2 diabetes mellitus in patients with HbA1C values > 9% is by administering insulin or a combination of insulin with oral hypoglycemic agents. This study aims to determine the suitability of the type and dose of insulin in type 2 DM patients in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang. This research is a descriptive observational study using retrospective data. The data were obtained from the medical records of Universal Health Coverage participant patients with type 2 diabetes mellitus in the Outpatient Pharmacy Installation of St. Elisabeth Hospital Semarang, who only received insulin therapy in January 2020, is 26-65 years old, and has examination results for fasting blood glucose, post prandial blood glucose and HbA1C (examination results for the last 6 months). The results showed that 57 patients consisted of 29 (50.88%) male patients and 28 (49.12%) female patients. A total of 47 (82.46%) patients were more than 45 years old. A total of 38 patients (66.67%) received combination insulin and all patients had HbA1C values> 9%. The suitability of using insulin based on the type of insulin was 68.42% and most of the patients (80.70%) received inappropriate insulin doses.
EVALUASI TERAPI ADJUVAN DAN KEJADIAN RELAPS PADA PASIEN PREMENOPAUSAL EARLY BREAST CANCER DI RSUP DR. SARDJITO YOGYAKARTA Fef Rukminingsih; Tri Murti Andayani; Fita Rahmawati; Kartika Widayati
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 7, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.364

Abstract

Terapi adjuvan pada pasien early breast cancer (EBC) bertujuan untuk meningkatkan disease free survival, menurunkan risiko relaps dan menurunkan angka kematian. Tetapi pada kenyataannya masih sering dijumpai, pasien EBC yang telah mendapat terapi adjuvan mengalami relaps. Kejadian relaps sering dihubungkan dengan meningkatnya risiko kematian tanpa memperhatikan jenis pengobatan. Tujuan penelitian ini adalah mengetahui angka kejadian relaps pada pasien premenopausal EBC yang telah mendapatkan terapi adjuvan di RSUP dr. Sardjito Yogyakarta. Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross sectional study menggunakan data retrospektif yang diperoleh dari data rekam medik pasien premenopausal EBC di Poliklinik Kanker Terpadu “Tulip” RSUP dr. Sardjito Yogyakarta yang telah mengalami tindakan pembedahan pada tahun 2010-2013, bersifat hormon responsif dan HER-2 negatif, mendapatkan terapi adjuvan, perempuan dengan umur 18-60 tahun dan  riwayat pemeriksaan sampai bulan Desember 2016. Pasien akan di eksklusi bila mempunyai penyakit penyerta. Dari 30 pasien diketahui sebanyak 46,67% berumur 41-50 tahun, sebanyak 63,33% menunjukkan ekspresi ER-PR positif, sebanyak 93,34% merupakan invasive ductal carcinoma (IDC). Semua pasien mendapatkan terapi adjuvan kemoterapi menggunakan regimen kombinasi dan semua pasien mendapatkan terapi endokrin berupa tamoksifen. Relaps terjadi pada 11 pasien (36,67%) dan kejadian relaps paling banyak adalah metastasis tulang yaitu pada 8 pasien (26,67%).
EVALUATION ON THE THERAPY APPROPRIATENESS AND ANTIHYPERTENSIVE AGENT SIDE EFFECTS TOWARD TYPE 2 DIABETES MELLITUS WITH CHRONIC KIDNEY DISEASE PATIENTS RECEIVING REGULAR HAEMODIALYSIS AT RSU PKU MUHAMMADIYAH YOGYAKARTA Fef Rukminingsih; Djoko Wahyono; I Dewa Putu Pramantara
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 1, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.47

Abstract

Antihypertensive selection accuracy determines the achievement of therapy target toward type 2 diabetes mellituswith chronic kidney disease patients who received regular hemodialysis treatment. The use of drugs in a longtimepotentially causes side effects and drug interactions as well.This research employed prospective observation by evaluating the appropriateness of therapy and monitoringdirectly the side effects of antihypertensive agent used toward type 2 diabetes mellitus with chronic kidney diseasepatients who received regular haemodialysis treatment at RSU PKU Muhammadiyah Yogyakarta during February– April 2011.For 42 patients having type 2 diabetes mellitus with chronic kidney disease who received regular haemodialysis treatment, it was found that patients who received appropriate therapy and achieved blood pressure therapy target was none, 4 patients (9.53%) received appropriate therapy yet the blood pressure remained uncontrolled, 2 patients(4.76%) received inappropriate therapy yet achieved controlled blood pressure and 36 patients (85.71%) receivedinappropriate therapy with remained uncontrolled blood pressure. From 42 patients, it was found that there were 11patients (26,20%) were possible and 5 patients (11,90%) were probable suffered from dry cough, 26 patients (61.91%) were possible for suffered from dizziness, 39 patients (92.86%) were possible suffered from headache, 2 patients (4.76%) were potentially suffered from fatigue and 13 patients (30,95%) were possible and 2 patients (4,76%) wereprobable suffered from drowsiness. Keywords: antihypertensive, type 2 diabetes mellitus, haemodialysis
Uji Efek Hipoglikemia Ekstrak Daun Bandotan (Ageratum conyzoides L) pada Tikus Jantan (Rattus norvegicus) Galur Wistar Fef Rukminingsih; Paulina Maya Octasari; Oktavia Dwi Danira
Jurnal Akademi Farmasi Prayoga Vol 7 No 2 (2022): JURNAL AKADEMI FARMASI PRAYOGA
Publisher : Akademi Farmasi Prayoga Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56350/jafp.v7i2.83

Abstract

Abstrak Hipoglikemik adalah suatu keadaan yang menunjukkan kadar glukosa darah ≤ 70mg/dL. Daun bandotan (Ageratum conyzoidez L) mengandung senyawa flavonoid yang diduga memiliki aktivitas menurunkan kadar glukosa darah. Penelitian ini bertujuan untuk menguji efek hipoglikemik ekstrak daun bandotan (EDB) dan pengaruh variasi dosis EDB terhadap efek hipoglikemik pada tikus jantan galur Wistar. Penelitian ini merupakan penelitian eksperimental dengan rancangan acak lengkap pola searah satu faktor. Variabel yang diukur adalah kadar glukosa darah berupa efek hipoglikemik EDB pada tikus jantan galur Wistar. Sebanyak 25 ekor tikus dibagi dalam 5 kelompok perlakuan. Kelompok I kontrol negative CMC-Na 0,5%, kelompok II kontrol postif glibenklamid 0,04 mg/mL, kelompok III, IV, V diberi EDB dengan variasi dosis 100, 200, 300 mg/kgBB. Pengukuran kadar glukosa darah dilakukan setelah 2 jam pemberian senyawa selama 5 hari berturut – turut. Analisis data menggunakan uji Shapiro wilk, dikatakan terdistribusi normal jika p > 0,05 dan uji levene dengan uji homogenitas nilai p > 0,05. Dilanjutkan uji One Way Anova dan uji post hoc dengan taraf kepercayaan 95%. Hasil penelitian menunjukan EDB positif mengandung flavonoid. Kelompok kontrol positif memiliki efek hipoglikemik (≤ 70mg/dl). Variasi dosis EDB yang memiliki kemampuan menurunkan kadar glukosa darah tetapi tidak memiliki efek hipoglikemik karena kadar glukosa darah setelah perlakuan >70 mg/dL pada pada tikus normal.
Peresepan Obat Dispepsia di Apotek Kharisma Semarang Pasca Gelombang Kedua Covid-19 Daisy Ariani; Fef Rukminingsih; Paulina Maya Octasari
Jurnal Akademi Farmasi Prayoga Vol 8 No 1 (2023): JURNAL AKADEMI FARMASI PRAYOGA
Publisher : Akademi Farmasi Prayoga Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstrak Dispepsia dideskripsikan sebagai gejala gangguan pencernaan yang menyebabkan rasa tidak nyaman, mual dan muntah. Gejala umum yang juga muncul adalah rasa perih, kembung, dan panas di daerah perut bagian atas. Pasca pandemic Covid-19 gelombang kedua, terjadi peningkatan resep untuk pasien dyspepsia di Apotek Kharisma Semarang. Apotek Kharisma merupakan salah satu apotek besar di Kota Semarang. Tujuan penelitian ini untuk mengetahui pola peresepan obat dispepsia di Apotek Kharisma Semarang. Penelitian ini merupakan penelitian deskriptif observasional dengan menggunakan data retrospektif. Data yang digunakan adalah lembar resep pasien dispepsia yang berumur 18-65 tahun, periode Agustus - Desember 2021. Data yang diambil meliputi umur, jenis kelamin, nama obat dan pemakaiannya. Data kemudian di analisis secara kualitatif dan kuantitatif. Jumlah resep yang diperoleh sebanyak 495 lembar resep. Jumlah pasien perempuan sebanyak 322 (65,05%). Sebagian besar berumur lebih dari 36 tahun sebanyak 338 pasien (68,28%). Sebanyak 409 pasien (82,63%) mendapat terapi tunggal, sebanyak 26 pasien (5,25%) mendapat terapi kombinasi 2 obat dan sebanyak 60 pasien (12,12%) mendapat terapi kombinasi 3 obat. Ada 14 jenis obat dyspepsia yang diresepkan yang berasal dari 7 golongan obat. Jenis obat yang paling banyak diresepkan adalah antasida baik untuk pemakaian tunggal maupun kombinasi. Kombinasi 2 obat yang paling banyakdigunakan adalah antasida dan golongan prokinetik. Antasida juga dikombinasikan dengan penghambat pompa H+ dan H2 blocker sebagai jenis 3 kombinasi obat terbanyak digunakan. Abstract Dyspepsia is a set of clinical symptoms consisting of stinging, bloating, heat, nausea, vomiting, and discomfort in the upper abdomen. After the second wave of the Covid-19 pandemic, there was an increase in prescriptions for dyspeptic patients at the Kharisma Pharmacy Semarang. This study aims to determine the pattern of prescribing dyspepsia drugs at the Kharisma Pharmacy Semarang. This study is an observational descriptive study using retrospective data. The data used are prescription sheets for dyspepsia patients aged 18-65 years, the period August-December 2021.The data taken include age, gender, name of the drug and its use. The data is then analyzed qualitatively and quantitatively. The number of recipes obtained as many as 495 recipe sheets. The number of female patients was 322 (65.05%). Most of them were more than 36 years old as many as 338 patients (68.28%). A total of 409 patients (82.63%) received single therapy, as many as 26 patients (5.25%) received combination therapy with 2 drugs and as many as 60 patients (12.12%) received combination therapy with 3 drugs. There are 14 types of dyspepsia drugs that are prescribed from 7 drug classes. The type of drug that is most widely prescribed is antacid either for single use or in combination. The most widely used combination of 2 drugs are antacids and prokinetic groups. While the combination of the 3 drugs most widely used are antacids, proton pump inhibitors and H2 receptor antagonists.
POTENSI ANTIDIABETIK EKSTRAK ETANOLIK BIJI SALAK (Salacca zalacca) PADA MENCIT PUTIH JANTAN GALUR SWISS (Mus musculus) YANG DIINDUKSI ALOKSAN Rukminingsih, Fef; Maya Octasari, Paulina; Kristi Nadila, Lilis; Aulia Putri, Fayza
Jurnal Insan Farmasi Indonesia Vol 6 No 2 (2023): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v6i2.1600

Abstract

Traditional medicine is an alternative treatment for diabetes mellitus. Flavonoids are compounds that have the activity of lowering blood glucose levels. Snake fruit (Salacca zalacca) contains flavonoids. This study aims to determine the antidiabetic potential of snake fruit ethanolic extract (SFEE) on male white Swiss mice. This research is an experimental study that consisted of 2 stages, namely testing the antidiabetic power and testing the hypoglycemia side effects of SFEE. Each stage was tested on 5 treatment groups. The various doses used were 91 mg, 114 mg, and 137 mg of 20g mice. In stage 1, fasting blood sugar checks are carried out on days 0, 3 and 17. Meanwhile, in stage 2, fasting blood sugar checks are carried out on days 1, 7 and 14. The positive control in the stage 1 test was metformin, while the stage 2 test used glibenclamide. The results showed that varying doses of SFEE  91 mg, 114 mg, and 137 mg of 20g mice had antidiabetic power of 62.87%, 68.07%, and 70.98%. The greater the dose of SFEE, the greater its antidiabetic power. However, the larger the dose of SFEE and the longer it is administered, the hypoglycemic effects will occur
Monitoring Tekanan Darah Pada Pasien Diabetes Melitus Tipe Dengan Hipertensi Di Puskesmas Tlogosari Kulon Kota Semarang Fef Rukminingsih; Putri Sri Wahyuni
Journal Clinical Pharmacy and Pharmaceutical Science Vol. 2 No. 2 (2023): Oktober : Journal of Clinical Pharmacy and Pharmaceutical Science
Publisher : Prodi D3 Farmasi Politeknik Katolik Mangunwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61740/jcp2s.v2i2.38

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion, insulin action, or both. DM is a risk factor for hypertension. Hypertension in DM increases the risk of complications so it is necessary to monitor whether blood pressure targets are achieved. This study aims to determine the achievement of blood pressure targets in type 2 DM patients with hypertension at the Tlogosari Kulon Health Center, Semarang City. This research is a descriptive observational study. Data collection uses purposive sampling technique. Data were obtained from medical records of type 2 DM patients with hypertension aged ≥ 45 years, who had blood pressure examination results on 2 consecutive visits in September 2022 – February 2023, use antihypertensives for at least 1 year. It was found 47 patients, consisting of 25 male patients and 22 female patients. A total of 26 patients were aged between 60-69 years. A total of 36 patients (76.59%) had taken antihypertensives for 1-5 years and 42 patients (89.40%) received single therapy, namely amlodipine. Only 1 patient received combination therapy of 2 drugs (amlodipine and candesartan). There were 14 patients who achieved the target blood pressure <140/90 mmHg (29.78%).
PENGUKURAN PERSEPSI TENAGA TEKNIS KEFARMASIAN DI KOTA DAN KABUPATEN SEMARANG TERHADAP APOTEK ONLINE Fef Rukminingsih; Azifatul Ula; Dian Safitri
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.636

Abstract

The development of online pharmacies in Indonesia will have an impact on the existence and role of Pharmaceutical Technicians. The number of pharmacies in Semarang City and Regency has reached almost 500 units. The number of Pharmaceutical Technicians who have practice permits in Semarang City is 477 people and in Semarang Regency is 115 people. Objective: This study aims to measure the perception of Pharmaceutical Technicians in Semarang City and Regency towards online pharmacies. Method: This research is a descriptive observational study using a cross sectional study design with using purposive sampling technique. The research data was obtained through a questionnaire in the form of a Likert scale which was distributed via google form in the Whatsapp group of Persatuan Ahli Farmasi Indonesia of Semarang City and Regency. Perceptions that are measured are drug guarantees, prices and consumer services. Pharmaceutical Technicians is said to have a positive perception of online pharmacies if the average score of the three parameters is in the range of 802.5 – 1284. Results: Respondents involved in this study were 321 respondents. Female respondents were 288 respondents (89.72%), 270 respondents (84.11%) aged less than 36 years and 177 respondents (55.14%) had Diploma III Pharmacy education. The drug guarantee parameter got a score of 1098, the drug price parameter got a score of 904 and the consumer service parameter got a score of 1035.5. The average score for the three parameters is 1012.5. Conclusion: Pharmaceutical Technicians in Semarang City and Regency have a positive perception toward online pharmacies.
Co-Authors Apriliyani Apriliyani Aulia Putri, Fayza Azifatul Ula Bayu Kristianto, Yosua Daisy Ariani Dewi, Restu Anita Sukma Dian Safitri Diyah Ikasari, Endang Djoko Wahyono Hanik Utaminingrum I Dewa Putu Pramantara Kartika Widayati Taroeno Hariadi Kristi Nadila, Lilis Megi Pangestuningsih Nike Kusuma Dewi Oktavia Dwi Danira Paulina Maya Octasari Pujiastuti, Anasthasia Putri Sri Wahyuni Rahmawati, Fita Rika Yulia Setyoningrum Pujiastuti Silvi, Niken Hidayatus Susanto, Theresia Carolina Tri Mulyani Tri Murti Andayani Valentina Catur Nova Vita, Cristin Yulia Widiastuti, Mei