Garuda - Garba Rujukan Digital

Perbandingan Efektivitas Pembelajaran Clinical Skill Lab (CSL) dengan Menggunakan Video Ajar Keterampilan Klinik Neurologi terhadap Demonstrasi oleh Instruktur Aryanty, Nindya; Puspasari, Anggelia; Purwakanthi, Anati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 2 No. 2 (2014): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background : Medical Faculty University of Jambi has been implemented clinical skills lab (CSL) as one of learning methode. Limited time for encounter a learning topic which discuss just once in learning session may effect student ability to perform clinical skill of learning topic. There are many research represent advantages of learning video as effective learning media to gained student memory for a learning topic. The aim of this research was to compared effectiveness student clinical skill neurology examination ability using learning video with direct instructor teaching perform. Student ability to perform clinical skill assess using checklist procedure. Methode: This research was true experimental with posttest only control design. This research held at Medical Faculty University of Jambi in June until August 2014. Population of this research was all student in first years. Sample randomly selected and grouped as experiment (69 students) and control (68 students). Experiment group gave clinical skill neurology examination video, control group gave direct instructor teaching perform. Result: Evaluation based on checklist represent of experiment group had median value 78,13 (range 50,00) and control group had median value 74,25 (range 75,76). Mann U-Whitney test find the p- value for compared two group was 0,657 (p>0,05), there was no significant statistically between experiment and control group. Conclusion : In conclusion student who did not follow clinical skill learning session can learned from video, video may consider as learning media to over come limitation human resources and time of lecture in medical faculty. Kata Kunci : Clinical Skill Lab, Learning video, Neurology clinical skill

GAMBARAN PENGGUNAAN OBAT DIABETES MELLITUS PADA PASIEN DIABETES MELLITUS TIPE 2 Purwakanthi, Anati; Shafira, Nyimas Natasha Ayu; Harahap, Huntari; Kusdiyah, Erny
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 8 No. 1 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v8i1.9483

ABSTRACT Introduction: According to the International Diabetes Federation (IDF), the number of people with DM worldwide in 2010 was 285 million. This number increased to 371 million people in 2012 and increased to 387 million people in 2014. This number will continue to increase beyond 600 million people in 2035. The prevalence of DM in Jambi province based on interviews diagnosed by doctors and symptoms by 1.1 percent. According to the United Kingdom Prospective Study (UKPDS) report, the most important chronic complications are cardiovascular disease, peripheral vascular disease, retinopathy, and diabetic nephropathy. Thus actually death in DM occurs not directly due to hyperglycemia, but is associated with complications that occur. The need for motivation and education from health workers regarding the use of DM drugs. Sometimes other drugs are needed to treat complications of DM. Methods: This study uses a prospective descriptive study. The data taken is secondary data by looking at the research variables recorded in the patient's medical record. The sample of this study were all patients with diabetes mellitus who were treated at Raden Mattaher Hospital in May to September 2019 (total sampling). Results: Most patients with diabetes mellitus were aged ≥ 45 years, ie 67 people. The longest use of diabetes mellitus drugs is more than 1 year to 3 years, which is 30 people. The most widely used diabetes mellitus drug, insulin aspart, is 27 people. How to use diabetes mellitus drug is a single insulin as many as 32 people. Conclusion: Diabetes Mellitus Type 2 tends to occur in the elderly at most more than 1 year to 3 years using the most diabetes mellitus diabetes drug administered by means of a single insulin. Keywords: DM type 2, Diabetes Mellitus drugs, how to use ABSTRAK Pendahuluan Menurut International Diabetes Federation (IDF), jumlah penderita DM di seluruh dunia pada tahun 2010 adalah 285 juta orang. Angka ini meningkat menjadi 371 juta orang pada tahun 2012 dan meningkat menjadi 387 juta orang pada tahun 2014. Angka ini akan terus meningkat melampaui 600 juta orang pada tahun 2035. Prevalensi penyakit DM di provinsi Jambi berdasarkan wawancara yang terdiagnosis dokter dan gejala sebesar 1,1 persen. Menurut laporan United Kingdom Prospective Study (UKPDS), Komplikasi kronis paling utama adalah penyakit kardiovaskuler, penyakit pembuluh darah perifer, retinopati, serta nefropati diabetik. Dengan demikian sebetulnya kematian pada DM terjadi tidak secara Iangsung akibat hiperglikemianya, tetapi berhubungan dengan komplikasi yang terjadi. Perlunya motivasi dan edukasi dari petugas kesehatan tentang penggunaan obat DM. Terkadang diperlukan obat lain untuk mengobati komplikasi dari DM. Metode Penelitian ini menggunakan penelitian deskriptif prospektif. Data yang diambil adalah data sekunder dengan melihat variabel-variabel penelitian yang tercatat pada rekam medik pasien. Sampel penelitian ini adalah semua pasien diabetes mellitus yang berobat di RS Raden Mattaher pada bulan mei sampai september 2019 (total sampling). Hasil Pasien yang terkena diabetes mellitus terbanyak pada umur ≥ 45 tahun, yakni 67 orang. Lama penggunaan obat diabetes mellitus paling banyak lebih dari 1 tahun hingga 3 tahun yakni 30 orang. Obat diabetes mellitus yang paling banyak digunakan yakni insulin aspart sebanyak 27 orang. Cara penggunaan obat diabetes mellitus yaitu insulin tunggal sebanyak 32 orang. Kesimpulan Diabetes mellitus tipe 2 cenderung terjadi pada usia lanjut paling banyak lebih dari 1 tahun hingga 3 tahun menggunakan obat diabetes mellitus terbanyak insulin aspart yang diberikan dengan cara insulin tunggal. Kata kunci : DM tipe 2, obat Diabetes Mellitus, cara penggunaan

PENGARUH PENGGUNAAN ANTIBIOTIK PROFILAKSIS DENGAN LAMA RAWAT INAP PADA PASIEN SEKSIO SESAREA Huntari, Huntari; Purwakanthi, Anati; Kusdiyah, Erny
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 8 No. 2 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Introduction Women who have a cesarean delivery have a 5-20 times greater risk of infection than normal delivery. Antibiotics given to surgical patients aim to reduce the number of bacterial colonies, reduce the amount of inoculum contamination so that prophylactic antibiotics are needed to reduce the risk of infection or as therapy if they are already in a previous infection state. Aim of this study was to determine the effect of prophylactic antibiotic use and length of stay in cesarean section. Method this research uses analytical research with a cross sectional approach. There were 318 patients who met the study inclusion criteria. The assessment of research variables used secondary data from the medical records of patients with cesarean section at Raden Mattaher Hospital Jambi in 2018. Results of this study were patients with caesarean section at Raden Mattaher Hospital Jambi in 2018, at most 20 to 35 years, 240 people, 135 primigravidas people, 244 people with a history of first cesarean section, used a prophylactic antibiotic for cesarean section, namely ceftriaxone once two grams for 3 days, with the most diagnosis of cesarean section due to premature rupture of the membranes as many as 87 people. There was a relationship between the type of prophylactic antibiotics given (p = 0.00), the number of antibiotics (p = 0.00), and the diagnosis before cesarean delivery (p = 0.00) with the length of Inpatient. Keywords: Antibiotics, Caesarean section, Inpatient ABSTRAK Pendahuluan Wanita yang melakukan persalinan secara bedah sesar memiliki resiko infeksi lebih besar 5-20 kali lipat dibandingkan persalinan normal. Antibiotik yang diberikan pada pasien bedah bertujuan untuk mengurangi jumlah koloni bakteri, mengurangi jumlah inokulum kontaminasi sehingga diperlukan pemberian antibiotik profilaksis untuk menurunkan risiko infeksi atau sebagai terapi apabila sudah dalam keadaan infeksi sebelumnya. Tujuan penelitian ini untuk mengetahui pengaruh penggunaan antibiotik profilaksis dengan lama rawat inap seksio sesaria. Metode Penelitian ini merupakan penelitian analitik dengan metode cross sectional. Terdapat 318 pasien memenuhi kriteria inklusi penelitian . Penilaian variabel- penelitian menggunakan data sekunder dari rekam medik pasien seksio sesaria di Rumah Sakit Raden Mattaher Jambi tahun 2018. Hasil penelitian pasien seksio sesaria di Rumah Sakit Raden Mattaher Jambi tahun 2018, paling banyak berumur 20 hingga 35 tahun yakni 240 orang, primigravida 135 orang, riwayat seksio sesaria pertama kali sebanyak 244 orang, menggunakan antibiotik profilaksis seksio sesaria yakni ceftriaxon sebanyak satu kali dua gram selama 3 hari, dengan diagnosis terbanyak seksio sesaria dikarenakan ketuban pecah dini sebanyak 87 orang. Terdapat hubungan antara jenis antibiotik profilaksis yang diberikan (p = 0,00) dan jumlah pemberian (p=0,00) dengan lama rawat inap. . Kata kunci : Antibiotik, Seksio sesaria, Rawat Inap

ANTIBACTERIAL ACTIVITY OF ARECA NUT SOAP FORMULATION AGAINST STAPHYLOCOCCUS AUREUS Rahman, Ave Olivia; Purwakanthi, Anati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 1 (2021): Special Issues: JAMHESIC 2020
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACTBackground: Areca nuts are widely grown in Jambi and areca seeds have antibacterial activity, antioxidant, skinaging and cosmetics. It has the potential to be developed as antibacterial soap.Objective: This study was to compare the antibacterial effect of betel nut concentration powder and extract in oursoap formulation against Staphylococcus aureus using the in vitro test.Method: Soap formulation was made with 3 concentration of areca nut powder in soap, namely 1,5 grams/soap(soap 1); 2,3 grams/soap (soap 2) and 3 grams/soap (soap 3). also with extract of areca nut 1,2 grams/soap (soap4). The final weight of soap was obtained 50 grams. Antiseptic soap brand X and Y as a control. Antibacterialactivity test using Staphylococcus aureus ATCC 25923 with the well method.Results: The diameter of the clear zone produced by each areca nut soap was not much different (p>0,05). Theclear zone diameter of soap 1, 2, 3 and 4 were 24.28 ± 7,95 mm, 23,96 ± 6,41 mm, 23,87 ± 6,14 mm, and 23,08± 1,52 mm respectively. While, diameter of clear zone in brand X and Y were zero. Conclusion: The betel nutsoap formulation in this study has better antibacterial activity against Staphylococcus aureus ATCC 25923 thancontrol.Keywords: soap, areca nut, antibacterial, Staphylococcus aureusABSTRAKLatar Belakang: . Pohon pinang banyak ditanam di Jambi dan biji pinang memiliki aktivitas antibakteri, antioksidan,anti penuaan dan kosmetik. Biji pinang berpotensi untuk dikembangkan sebagai sabun antibakteri.Tujuan: Penelitian ini membandingkan efek antibakteri sabun pinang dengan bahan aktif dalam bentuk serbukdan eksktrak terhadap Staphylococcus aureus menggunakan uji in vitro.Metode: Formulasi sabun dibuat dengan 3 kadar serbuk pinang dalam sabun, yaitu 1,5 gram / sabun (sabun 1);2,3 gram / sabun (sabun 2) dan 3 gram / sabun (sabun 3), serta ekstrak biji pinang 1,2 gram/sabun. Berat akhirsabun diperoleh 50 gram. Sabun antiseptik merek X dan Y sebagai kontrol. Uji aktivitas antibakteri menggunakanStaphylococcus aureus ATCC 25923 dengan metode sumur.Hasil: Diameter zona bening yang dihasilkan masing-masing sabun pinang tidak jauh berbeda (p>0,05). Diameterzona bening sabun 1, 2 , 3 dan 4 masing-masing adalah 24.28 ± 7,95 mm, 23,96 ± 6,41 mm, 23,87 ± 6,14 mm,dan 23,08 ± 1,52 mm. Sedangkan diameter zona bening pada merek X dan Y adalah nol. Kesimpulan: Formulasisabun pinang pada penelitian ini memiliki aktivitas antibakteri yang lebih baik terhadap Staphylococcus aureusATCC 25923 daripada sabun control.Kata kunci: sabun, pinang, antibakteri, Staphylococcus aureus

EFFEKTIVITAS MADU JAMBI SEBAGAI ANTI ADHESIVE INTRA PADA LUKA BERSIH TIDAK TERKONTAMINASI Miftahurahmah, Miftahurahmah; Purwakanthi, Anati
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Abstrak Latar belakang: Adhesi peritoneum setelah pembedahan merupakan akibat dari cedera permukaan peritoneum dan iskemik jaringan. Zat anti adhesi merupakan salah satu metode menurunkan kejadian adhesi. Madu merupakan salah satu obat yang memiliki sejarah panjang sebagai anti adhesive, antibakteri, dan penyembuhan luka. Tujuan penelitian ini adalah untuk mengetahui efektivitas madu Jambi dalam pencegahan pembentukan adhesi intraabdomen. Metode: 24 tikus laki-laki jenis wistar dibagi menjadi empat kelompok. Kelompok control sebagai kelompok A, kelompok NaCl 0.9% sebagai kelompok B, kelompok Madu minimal sebagai kelompok C dan kelompok madu maksimal sebagai kelompok D. penilaian dilakukan pada hari ke 10 dimana data yang dikumpulkan berupa identifikasi adhesi, derajat adhesi secara makroskopis sedangkan penilaian mikroskopis berupa vascular endothelial cell, sel inflamasi, dan sel fibroblast cell Hasil: adhesi secara makroskopis pada kelompok A sebanyak 6 tikus, kelompok B sebanyak 6 tikus, kelompok C sebanyak 2 tikus and kelompok D sebanyak 2 tikus. Perbandingan kejadian adhesi antara dua kelompok yaitu kelompok A vs C memiliki hasil bermakna (p: 0.014) dan kelompok A vs D bermakna (p: 0.014). perbandingan kelompok berdasarkan derajat adhesi memiliki hasil yang bermakna pada kelompok A vs C (P: 0.041). perbandingan secara mikroskopis berdasarkan sel fibroblast tidak memberikan hasil yang bermakna. kesimpulan: Madu Jambi memberikan efek anti adhesive pada luka bersih tidak terkontaminasi Kata kunci: madu, anti adhesive, efektivitas

AKTIVITAS ANTIBAKTERI MINYAK ESENSIAL KULIT KAYU MANIS (CINNAMOMUM ZEYLANICUM) IN VITRO Purwakanthi, Anati; Rahman, Ave Olivia
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: Cinnamon bark has long been used as a traditional medicine. Cinnamon is also used as an aromatic spice and a flavoring additive in many cuisines around the world. Cinnamon contains cinnamaldehyde which is known to have antibacterial activity The aim of the study: to test the antibacterial effect of Cinnamon bark essential oil invitro. Methods: The antibacterial activity test was carried out in vitro using the disc diffusion method (Kirby-Bauer), with six concentrations of cinnamon bark essential oil, namely 1, 2, 4, 8, 16, and 32πl / ml. The bacteria used were Escherichia coli ATCC 25922, Streptococcus pneumoniae ATCC 49619 and Pseudomonas aeruginosa ATCC 27853 Results: The diameter of the clear zone formed was different at each concentration (p<0.05), both for E. coli S. pneumoniae or P. aeruginosa bacteria. Conclusion: Cinnamon bark essential oil have antibacterial activity against E.coli, S. Pneumoniae and P. Aeruginosa bacteria Keyword: Cinnamon bark, Essential oil, Antibacterial activity ABSTRAK Latar Belakang: Kulit kayu manis sudah sejak lama digunakan sebagai obat tradisional. Kayu manis juga digunakan sebagai bumbu aromatik dan aditif penyedap dalam berbagai masakan hampir di seluruh dunia. Kayu manis memiliki kandungan cinnamaldehyde yang diketahui memiliki aktivitas antibakteri. Tujuan penelitian: Menguji efek antibakteri minyak esensial kulit kayu manis secara invitro. Metode: Uji aktivitas antibakteri dilakukan secara in vitro menggunakan metode difusi cakram (Kirby-Bauer), dengan enam konsentrasi minyak esensial kulit kayu manis yaitu 1, 2, 4, 8, 16, dan 32πl / ml. Bakteri yang digunakan adalah Escherichia coli ATCC 25922, Streptococcus pneumoniae ATCC 49619 dan Pseudomonas aeruginosa ATCC 27853 Hasil: Diameter zona bening yang terbentuk berbeda pada masing-masing konsentrasi (p<0,05), baik pada bakteri E. coli S. Pneumoniae ataupun P. Aeruginosa . Kesimpulan: Minyak esensial kulit kayu manis memiliki aktivitas antibakteri terhadap bakteri E. coli S. Pneumoniae dan P. Aeruginosa Kata kunci: Kulit kayu manis, Minyak esensial, Aktivitas antibakteri

UJI AKTIVITAS ANTIBAKTERI MINYAK ESSENSIAL SEREH (CYMBOPOGON FLEXUOSUS) TERHADAP BAKTERI SALMONELLA ENTERICA DAN ESCHERICHIA COLI IN VITRO Purwakanthi, Anati; Miftahurahmah, Miftahurrahmah
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACTBackground: Gastrointestinal disease is still one of the main problems in health problems. One of the causes is abacterial infection. Lemongrass is a common plant and is easily available in Indonesia and has antibacterial activity.The aim of the study: to test the antibacterial effect of lemongrass essential oil against Salmonella enterica and E.Coli by invitro.Methods: The bacteria used were S. Enterica ATCC 35664 and E. Coli ATCC 25922.The antibacterial activity testwas carried out in vitro using the disc diffusion method (Kirby-Bauer), with 4 concentrations of lemongrass essentialoil : 1, 5, 10, and 20 πl / ml, positive control (ciprofloxacin disk 0.5 µg) and negative control (palm oil).Results: There were no clear zones for the inhibition of salmonella enterica and E. coli bacteria.Conclusion: Lemongrass essential oil does not have antibacterial activity against S. Enterica and E. Coli bacteriaKeyword: Lemongrass, Essential oil, Antibacterial activityABSTRAKLatar Belakang: Penyakit saluran cerna masih menjadi salah satu permasalahan utama dalam masalah Kesehatan.Salah satu penyebabnya adalah karena infeksi bakteri. Sereh merupakan tanaman yang umum dan mudah didapatdi Indonsesia dan memiliki aktivitas antibakteri.Tujuan penelitian: untuk menguji efek antibakteri minyak esensial sereh terhadap bakteri Salmonella enterica dan E.Coli secara invitro.Metode: bakteri yang digunakan adalah S. Enterica ATCC 35664 dan E. Coli ATCC 25922. Uji aktivitas antibakteridilakukan secara invitro dengan menggunakan metode difusi cakram (Kirby-Bauer), dengan 4 konsentrasi minyakesensial sereh yaitu 1, 5, 10, dan 20 πl/ml , kontrol positif (ciprofloxacin disk 0,5µg) dan kontrol negatif (minyakkelapa sawit).Hasil: Tidak didapatkan zona bening penghambatan bakteri salmonella enterica dan E. coli.Kesimpulan : minyak essensial sereh tidak memiliki aktivitas antibakteri terhadap bakteri S. Enterica dan E. ColiKata kunci: Sereh, Minyak esensial, aktivitas antibakteri

Effect of essential oil on hypertrophic scars Rahman, Ave Olivia; Humaryanto, Humaryanto; Purwakanthi, Anati; Simanjuntak, Charles Apul
MEDISAINS Vol 19, No 1 (2021)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v19i1.10192

Background: Hypertrophic scars are abnormal scars resulted from a disrupted wound healing process. Hypertrophic scars can affect the body aesthetic of the sufferers, but, on the other hand, conventional therapy has not been optimally effective. The application of essential oil combinations as an alternative therapy for hypertrophic scars has not been scientifically proven.Purposes: This study was to determine the effectiveness of the essential oil as a hypertrophic scar therapy.Methods: This study used a pre and post-test design. As many as 24 subjects aged 17-25 years with hypertrophic scars were given essential oil combinations every morning and evening for six months. Assessment of hypertrophic scars was done using the POSAS (Patient and Observer Scar Assessment Scale).Results: The results showed that the POSAS score decreased after the essential oil combination administration for six months, 14.40±6.08 vs. 22.67±8.31 (p<0.001).Conclusion: the combination of essential oil oils used in this study reduces hypertrophic scars based on the POSAS assessment.

Antifertility effect of betel nut (Areca catechu L) in male rat Rahman, Ave Olivia; Purwakanthi, Anati; Dewi, Hasna
MEDISAINS Vol 18, No 2 (2020)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v18i2.7588

Background: Betel nut (Areca catechu L) are traditional beverages in Jambi. Betel nut high dose has a cytotoxic effect on testis and other organs—limited data about the effect of betel nut as male antifertility.Purposes: This study aimed to determine the effect of infertility on betel nut use at a dose of 50 mg/kg body weight (BW) in male rats. Methods: Ten male Sprague Dawney rats that had passed the fertility test, aged 2-3 months and weighing 150-200 grams ware used in this study. The rat was grouped into two groups randomly. Group 1, as the negative control, were received aqua dest, and group 2 was treated by betel nut with dose 50 mg/kg BW for 35 days. When terminated, testis weight weighed using micro scales. Blood collected for measuring testosterone levels. Histopathology assessment of testis used Hematoxylin Eosin Staining and sperm counting from cauda epididymis.Results: The weight of testis in the group received betel nut was lower than the control group. The histopathology of testis showed shrunk, reduced the diameter of seminiferous tubules, and like cytolytic lesions in the germinal layer—the total sperm number and progressive sperms also lower than the control group (p<0.05). There was no abnormality in Leydig cell and interstitium tissue. Male rats after treatment could not impregnate the female rats.Conclusion: Betel nut at dose 50 mg/kg BW have antifertility activity in male rats.

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