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DETEKSI DINI OSTEOPOROSIS PASCA MENOPAUSE aurora, wahyu indah dewi; Humaryanto, Humaryanto
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 5 No. 2 (2017): JAMBI MEDICAL JOURNAL Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Abstract Osteoporosis occurs when the process of bone erosion and bone formation become unbalanced. The cells that cause bone erosion (osteoclasts) begin to make canals and holes in bone faster than the work of osteoblast-producing cells that create new bone to fill the hole, so bone decreases bone mass density and worsening bone microarchitecture Postmenopausal osteoporosis is caused by an estrogen deficiency. Estrogen plays a very important role in bone metabolism, affecting the activity of osteoblast cells and osteoclasts, including maintaining the work balance of both cells. Because osteoporosis is a disease that usually does not start with symptoms, the most important step in preventing and treating osteoporosis is early checking for early detection so that from this examination will be known next step. Keywords: Osteoporosis, Post menopause, Early Checking Abstrak Osteoporosis terjadi ketika proses pengikisan tulang dan pembentukan tulang menjadi tidak seimbang. Sel-sel yang menyebabkan pengikisan tulang (osteoklas) mulai membuat kanal dan lubang dalam tulang lebih cepat daripada kerja sel-sel pemicu pembentukan tulang (osteoblas) yang membuat tulang baru untuk mengisi lubang tersebut, sehingga tulang mengalami penurunan densitas massa tulang dan perburukan mikroarsitektur tulang, Osteoporosis pasca menopause disebabkan karena adanya defisiensi estrogen slot deposit 5000. Estrogen memegang peran yang sangat penting dalam metabolisme tulang, mempengaruhi aktivitas sel osteoblas maupun osteoklas, termasuk menjaga keseimbangan kerja dari kedua sel tersebut. Karena osteoporosis merupakan suatu penyakit yang biasanya tidak diawali dengan gejala, maka langkah yang paling penting dalam mencegah dan mengobati osteoporosis adalah pemeriksaan secara dini untuk deteksi awal sehingga dari pemeriksaan ini akan diketahu langkah selanjutnya. Katakunci: Osteoporosis, Pasca Menopause, Deteksi dini

PERBEDAAN ANTARA pH SALIVA DAN AKTIVITAS ENZIM AMILASE MAHASISWA YANG MEROKOK DENGAN MAHASISWA YANG TIDAK MEROKOK Syauqy, Ahmad; Humaryanto, Humaryanto
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 6 No. 1 (2018): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Introduction: Cigarettes can cause disturbances in the oral cavity. From previous research it is known that the daily consumption of cigarettes increases the decrease of salivary secretion and the content of bicarbonate. This will have an effect on the decrease of pH saliva. Low salivary pH also has an impact on decreased amylase enzyme activity. Departing from the basic theory, the researchers wanted to see if there are differences in salivary pH and amylase enzyme activity in students who smoke with non-smokers at the Faculty of Medicine and Health Sciences Jambi University. Methods This study is a case control study that compares two groups consisting of case groups ie students who smoke and control groups ie students who do not smoke with the number of research samples compared to 1: 1. For the case group, the samples were taken in total sampling from the Jambi University medical students who smoked 39 people while the control group was taken from the non-smoking students of 39 persons who chose proportional random sampling. Performed salivary pH examination and measurement of ptialin enzyme activity on respondents. The research data were tested statistically using Independent t-test to see the difference of salivary pH and amylase enzyme activity in students who smoked with non-smokers. Results Mean pH saliva of students who smoke is 6.64 ± 0.25. The mean pH of non-smoking student saliva was 7.04 ± 0.28. The average of enzyme activity of amylase student who smoke is 16,33 ± 7,51 second. The average activity of non-smoking student amylase enzyme was 4.28 ± 2.68 seconds. The P value for the Independent t test of saliva pH and amylase enzyme activity among students who smoked with non-smokers was 0.00. Conclusions: There was a significant difference between salivary pH and amylase enzyme activity among smoking students with non-smokers. Keywords: smoking, salivary pH, amylase ABSTRAK Pendahuluan: Rokok dapat menyebabkan gangguan pada rongga mulut. Dari penelitian sebelumnya diketahui bahwa konsumsi rokok harian yang meningkat berdampak terhadap penurunan sekresi saliva dan kandungan bikarbonat. Hal ini akan berdampak pada terjadinya penurunan pH saliva. pH saliva yang rendah juga berdampak pada penurunan aktivitas enzim amilase. Berangkat dari dasar teori tersebut, peneliti ingin melihat apakah ada perbedaan pH saliva dan aktivitas enzim amilase pada mahasiswa yang merokok dengan mahasiswa yang tidak merokok di Fakultas Kedokteran dan Ilmu Kesehatan universitas Jambi. Metode Penelitian ini merupakan penelitian case control yang membandingkan 2 kelompok yang terdiri atas kelompok kasus yaitu mahasiswa yang merokok dan kelompok kontrol yaitu mahasiswa yang tidak merokok dengan jumlah sampel penelitian berbanding 1:1. Untuk kelompok kasus, sampel diambil secara total sampling dari mahasiswa kedokteran Universitas Jambi yang merokok sejumlah 39 orang sedangkan kelompok kontrol diambil dari mahasiswa yang tidak merokok sejumlah 39 orang yang pilih secara proporsional random sampling. Dilakukan pemeriksaan pH saliva dan pengukuran aktivitas enzim ptialin pada responden. Data penelitian yang didapat diuji secara statistik menggunakan Independent t-test untuk melihat perbedaan pH saliva dan aktivitas enzim amilase pada mahasiswa yang merokok dengan mahasiswa yang tidak merokok. Hasil Rerata pH saliva mahasiswa yang merokok adalah 6,64±0,25. Rerata pH saliva mahasiswa yang tidak merokok adalah 7,04±0,28. Rerata aktivitas enzim amilase mahasiswa yang merokok adalah 16,33±7,51 detik. Rerata aktivitas enzim amilase mahasiswa yang tidak merokok adalah 4,28±2,68 detik. Nilai P untuk Independent t test dari pH saliva dan aktivitas enzim amilase antara mahasiswa yang merokok dengan mahasiswa yang tidak merokok adalah 0,00. Kesimpulan: Terdapat perbedaan yang bermakna antara pH saliva dan aktivitas enzim amilase antara mahasiswa yang merokok dengan mahasiswa yang tidak merokok. Kata Kunci: merokok, pH saliva, amilase

PENILAIAN RISIKO JATUH DENGAN PENGGUNAAN TIMED UP AND GO TEST PADA PENDERITA OSTEOARTHRITIS GENU GRADE 1 - 3 Humaryanto, Humaryanto; Tobing, Maudy Rominar Br
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 3 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (344.772 KB)

ABSTRACT Background: Knee osteoarthritis (OA) is the most common form of arthritis. The presence of knee pain, decreased functional mobility, stiffness, and decreased quadriceps strength in knee OA patients can cause physical disability. In optimizing the patient's functional mobility to perform activities of daily living, a valid and reliable tool is needed at the beginning and after the intervention. The purpose of this study was to measure functional mobility by assessing the risk of falling using the TUG test in patients with knee OA grade 1 to grade 3. Methods: A descriptive study with 93 samples of knee OA patients at the Orthopedic Surgery Clinic of the hospital. Data were obtained from interviews, medical records, and observation sheets. Results: Based on age, knee OA was most common in patients in the late elderly group, namely 45 patients (48.4%). Based on gender, knee OA is more common in women (84%) than men (16,1%). Based on Body Mass Index (BMI), the results of a normal BMI are the same as those of heavy fat (42%). From the radiological examination results, patients with genu OA were at K/L 2 degrees as many as 46 patients (49.4%). On the TUG test results, knee OA patients with a low risk of falling were 68 patients (73.1%). Knee OA patients who have a low risk of falling are more experienced by knee OA patients with BMI in the heavy fat category, namely 28 patients (30.1%). Patients with grade K/L 1 had the lowest fall risk as many as 17 patients (85%), patients with K/L 2 degrees had the lowest risk of falling as many as 38 patients (83%), patients with K/L 3 degrees had low fall risk equals moderate fall risk in 13 patients (48%). Conclusion: Knee OA patients both at grade 1, grade 2, and grade 3 have the lowest risk of falling and all knee OA patients have the risk of fallers due to their OA. Keywords: knee osteoarthritis, TUG test, Kellgren-Lawrence

IDENTIFICATION OF SCCMEC TYPE IN ISOLATE OF METHICILLIN RESISTANT Staphylococcus aureus (MRSA) IN JAMBI BY USING POLYMERASE CHAIN REACTION (PCR) Humaryanto, Humaryanto; Hanina, Hanina; Lipinwati, Lipinwati; Simanjuntak, Charles Apul
Indonesian Journal of Tropical and Infectious Disease Vol. 8 No. 2 (2020)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v8i2.12691

Staphylococcal cassette chromosome mec (SCCmec) is one of the mobile genetic elements of Methicillin-Resistant Staphylococcus aureus (MRSA) that carries many resistance genes and allows SCCmec to move from one bacterium to another. Twelve types of SCCmec have been identified throughout the world. Identification of SCCmec type is needed to determine the pattern of MRSA resistance in a particular region. This study aimed to identify the type of SCCmec MRSA from clinical samples. Specifically, this study was conducted at the Biomolecular Laboratory of the Faculty of Medicine and Health Sciences of Jambi University in June 2018-February 2019. Culture was carried out on 100 clinical specimens of festering wound swabs from inpatients at hopitals in Jambi City. A total of 32 samples of Staphytect plus test positive were tested using Cefoxitin disc diffusion method and MecA Polymerase Chain Reaction (PCR). There were 14 samples identified as MRSA isolates, namely twelve samples (85.72%) of SCCmec type III, one sample (7.14%) of SCCmec type II, and one sample (7.14%) of SCCmec type IVb. The results were different from previous studies where all MRSA isolates (100%) in Indonesia were SCCmec type III, although most SCCmec types were still dominated by SCCmec type III. This study concludes that there has been a shift in the content of SCCmec in MRSA isolate originating from hospitals in Jambi city.

Effect of essential oil on hypertrophic scars Rahman, Ave Olivia; Humaryanto, Humaryanto; Purwakanthi, Anati; Simanjuntak, Charles Apul
MEDISAINS Vol 19, No 1 (2021)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v19i1.10192

Background: Hypertrophic scars are abnormal scars resulted from a disrupted wound healing process. Hypertrophic scars can affect the body aesthetic of the sufferers, but, on the other hand, conventional therapy has not been optimally effective. The application of essential oil combinations as an alternative therapy for hypertrophic scars has not been scientifically proven.Purposes: This study was to determine the effectiveness of the essential oil as a hypertrophic scar therapy.Methods: This study used a pre and post-test design. As many as 24 subjects aged 17-25 years with hypertrophic scars were given essential oil combinations every morning and evening for six months. Assessment of hypertrophic scars was done using the POSAS (Patient and Observer Scar Assessment Scale).Results: The results showed that the POSAS score decreased after the essential oil combination administration for six months, 14.40±6.08 vs. 22.67±8.31 (p<0.001).Conclusion: the combination of essential oil oils used in this study reduces hypertrophic scars based on the POSAS assessment.

Antidiabetic effect of Psychotria malayana Jack in induced type 1 diabetic rat Fairuz, Fairuz; Dewi, Hasna; Humaryanto, Humaryanto
MEDISAINS Vol 18, No 1 (2020)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v18i1.6909

Background: Therapies for hyperglycemic treatment, including insulin and oral diabetes medications, have been confirmed to cause several side effects. Thus, finding new drugs with fewer side effects is of high importance. Salung leaf herb (Psychotria malayana Jack) reported used in traditional societies as a treatment for diabetes. However, the scientific proof of this plant for diabetes treatment is still lacking.Objective: To evaluate the antidiabetic effect of the P. malayana jack in induced type 1 diabetic rats by assessing blood glucose level and pancreatic cells in white rats.Methods: Alloxan used to induce type I diabetes. Rats randomly divided into six groups. A Group P1 received 250 mg/kg BW; group P2 received 500 mg/kg BW, group P3 received 1000 mg/kg BW. While group 4 basal received no treatment, group 5 received distilled water as a negative control, and group 6 received glibenclamide as a positive control. Medications are given for six days. Glucose levels were measured, and observation of pancreatic Langerhans cell damages.Results: A decrease in blood glucose levels observed in all treatment groups. The most significant reduction (49.76%; 1000 mg/kg BW) occurred in the P3 group. Morphological features of pancreatic Langerhans cell damage were slightly high in the P1 group.Conclusion: P. malayana Jack can consider having an antidiabetic effect in a type 1 diabetic rat by reducing blood glucose levels.

Antimicrobial effect of alkaloids extract of Areca catechu L Against Methicillin Sensitive Staphylococcus aureus Bacteria Humaryanto, Humaryanto; Lipinwati, Lipinwati; Hanina, Hanina; Halim, Rita
Riset Informasi Kesehatan Vol 14 No 2 (2025): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30644/rik.v14i2.871

Background: Infection caused by the bacterium Metihcillin Sensitive Staphyloccous aureus (MSSA) is still one of the infections that often occurs in humans. The emergence of various cases of resistance of MSSA bacteria to various antibiotics both in the community and in hospitals (nosocomial infections), has triggered the development of herbal medicines, one of which is the areca nut (Areca catechu L) which is thought to have antibacterial effects. The purpose of this research was to determine the antimicrobial effect of alkaloids in areca nut extract against MSSA bacteria. Method: Areca nut was extracted with 96% ethanol using the maceration method and continued with areca nut seeds and fractionation of the alkaloid active substances with ethanol-water, n-hexane and ethyl acetate (1:1) solvents. The sensitivity test of bacteria using the Kirby Bauer disc diffusion method with duplex repetitions. Amoxcillin clavulanat used as standard antimicrobial of antimicrobial test. Results: The extract components contained are alkaloids, flavonoids and tannins. Furthermore, the resistance test of MSSA bacteria to areca nut alkaloid extract and the amoxicillin antibiotic disc gave results of an average inhibitory zone diameter of 20.33 mm (strong activity) and 22.80 mm (strong activity). Conclusion: MSSA bacteria showed sensitivity to areca nut alkaloid extract with strong activity.

PATIENT'S PERCEPTION OF HIP AND KNEE OSTEOARTHRITIS IN A HOSPITAL IN JAMBI CITY Humaryanto, Humaryanto; Iskandar, Mirna; Simanjuntak, Patrick William Gading; Justitia, Budi; Mulyadi, Deri
Medical Dedication (medic) : Jurnal Pengabdian kepada Masyarakat FKIK UNJA Vol. 8 No. 1 (2025): MEDIC. Medical dedication
Publisher : Universitas Jambi

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Osteoarthritis (OA) is a degenerative joint disease, primarily affecting the elderly, and is classified into primary OA (with no specific cause) and secondary OA (caused by other diseases or conditions). Although it cannot be cured, appropriate management can control the symptoms and prevent disease progression. This study aims to assess the perception and knowledge of hip and knee OA patients in Jambi City using the Osteoarthritis Knowledge Scale (OAKS) instrument. Data were obtained from 87 patients at Kambang General Hospital: 54 filled out the Knee OAKS and 33 for Hip OAKS. The results showed that patients' understanding of general knowledge about OA was high (84%), but knowledge related to prevention was significantly lower (44%). Knowledge regarding treatment and symptom management was moderate (68.2%), and understanding of healthy lifestyle behaviors was 53%. These findings indicate a significant gap in patient knowledge, particularly regarding preventive measures and lifestyle modifications. Therefore, targeted educational interventions are crucial to improve patient understanding, enhance self-management, and ultimately achieve better clinical outcomes in managing OA. Keywords: Osteoarthritis, Patient Knowledge, OAKS, Health Education, Perception

MENGEMBANGKAN PENDIDIKAN BERDAYASAING GLOBAL PADA JURUSAN KEDOKTERAN MELALUI PENGEMBANGAN PANGKALAN DATA JURUSAN GUNA PENINGKATAN TATAKELOLA JURUSAN MENDUKUNG PEMENUHAN SASARAN STRATEGIS BASIS DATA ALUMNI DAN PRODUK KARYA DOSEN Suzan, Raihanah; Rahman, Ave Olivia; Humaryanto, Humaryanto; Syauqy, Ahmad; Miftahurrahma, Miftahurrahma; Maria, Ima
Scientific Of Environmental Health and Diseases (e-SEHAD) Vol. 2 No. 1 (2022): Electronic Journal Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

ABSTRACT Complete and appropriate data collection is part of the department's governance that needs special attention so that the management and quality assurance system in the department can run well and can provide a fast response to data requests. The fast response to data fulfillment certainly has an impact on the quality of the system in the department. This research was conducted to map and identify the data needs of the medical department that refers to the strategic plan, key performance indicators, and accreditation forms. The first step is to map the data into Microsoft Excel. The meeting involving the dean, lecturers, and staff produced a checklist of data that had been adjusted to the possibility of doubling data or missing data, and produced recommendations for SOPs needed according to the current situation. The details of the data that are the priority of the department include student data and lecturer data. The SOPs that were successfully formulated from the results of the discussion forums included SOPs for graduation, legalization, and employee performance appraisals. The data synchronization is then built into a website as a data center. Periodic evaluation and monitoring of the data center is required to keep the data up-to-date. Keywords: Governance, Department of Medicine ABSTRAK Pengumpulan data yang lengkap dan sesuai merupakan bagian dari tata kelola jurusan yang perlu mendapatkan perhatian khusus sehingga sistem pengelolaan dan penjaminan mutu di jurusan dapat berjalan dengan baik dan dapat memberikan respon yang cepat kepada kebutuhan permintaan data. Respon pemenuhan data yang cepat tentu berdampak pada kualitas sistem di jurusan. Penelitian ini dilakukan untuk memetakan dan mengidentifikasi kebutuhan data jurusan kedokteran yang mengacu pada renstra, indikator kinerja utama, dan borang akreditasi. Tahap awal yang dilakukan adalah memetakan data ke dalam Microsoft Excel. Pertemuan yang melibatkan pihak dekanat, dosen, dan staf menghasilkan daftar tilik data yang telah disesuaikan terhadap kemungkinan doubling data maupun missing data, serta melahirkan rekomendasi SOP yang dibutuhkan sesuai situasi saat ini. Rincian data yang menjadi priortias jurusan antara laina dalah data mahasiswa dan data dosen. SOP yang berhasil dirumuskan dari hasil forum diskusi antara lain adalah SOP yudisium, legalisir, dan penilaian prestasi kerja pegawai. Sinkronisasid ata tersebut kemudian dibangun dalam sebuah website sebagai pusat data. Evaluasi dan monitoring secara berkala terhadap pusat data dibuthkan untuk kemutakhiran data. Kata Kunci: Tatakelola, Jurusan Kedokteran

INOVASI PEMBELAJARAN BERBASIS DIGITAL SIMULASI TRIAGE KEGAWATDARURATAN TRAUMA Humaryanto, Humaryanto; Miftahurrahma, Miftahurrahma; Justisia, Budi
Scientific Of Environmental Health and Diseases (e-SEHAD) Vol. 2 No. 1 (2022): Electronic Journal Scientific of Environmental Health And Diseases
Publisher : LPPM Universitas Jambi

ABSTRACT Back ground: Morbidity and mortality were increase in trauma case, itâ€™s one of cause mortality under 45 years old in USA. In lower and middle income country mortality case in trauma were increase. This data would be challenge in medical faculty to increase understanding management of trauma in emergency unit. This research make an innovation of learning based on digital simulation of triage emergency of trauma. Methode: this is descriptive research, the data will be collect used evaluation question . the data will be analysed using SPSS. Result: in this research 74 responden were medical student in surgery department. This video was facilitate medical student to understanding trauma case(71.6%), interesting video (71.6%), This video was facilitate medical student to understanding management trauma (73%) Conclusion: learning innovation based on digital simulation in emergency trauma can helped to understanding managemen in emergency trauma dapat mempermudah mahasiswa memahami penatalaksanaannya. Key word: learning innovation, simulation, emergency trauma ABSTRAK Latar belakang: Morbiditas dan mortalitas kasus trauma di pusat kesehatan serta penyebab kematian ke empat untuk usia dibawah 45 tahun di Amerika serikat. Tingginya angka kematian pada kasus trauma dinegara berpendapatan rendah dan menengah, menjadi suatu tantangan bagi fakultas kedokteran dalam pemahaman penatalaksanaan kasus trauma. Oleh sebab itu penelitian ini bertujuan membuat Inovasi Pembelajaran Berbasis Digital berupa Simulasi Triage Kegawatdaruratan Trauma untyk meningkatkan pemahaman dalam penatalaksanaan kasus trauma. Metode: penelitian inibersifat deskriptif berupa penilaian mahasiswa mengenai video pembelajaran menggunakan instrument berupa kuesioner evaluasi video pembelajaran. Data dikumpulkan dan diolah menggunakan SPSS. Hasil: pada penelitian ini didapatkan 74 responden yang merupakan mahasiswa program studi profesi kedokteran yang telah melewati stase ilmu Penyakit bedah. Sebagian besar mahasiswa mengatakan bahwa video yang diberikan dapat mempermudah memahami learning objektif (71.6%), strategi pembelajaran menarik (71.6%), mempermudah memahami tindakan yang dilakukan pada kasus kegawatdaruratan trauma (73%). Kesimpulan: inovasi pembelajaran berbasis digital simulasi triage kegawatdaruratan trauma dapat mempermudah mahasiswa memahami penatalaksanaannya. Kata kunci: inovasi pembelajaran, simulasi, kegawatdaruratan trauma

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