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All Journal bionature SAINTIFIK@ : Jurnal Pendidikan MIPA As-syifaa Jurnal Farmasi Jurnal Ilmiah Farmako Bahari Jurnal Mandala Pengabdian Masyarakat Kieraha Medical Journal Pharmaceutical Reports Makassar Natural Product Journal
Safriani Rahman, Safriani
State University Of Makassar
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : Pharmaceutical Reports

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Phytochemical Screening of Ethanol Extract Qust Al Hindi roots (Saussurea lappa) Rahayu, Na'am Nur Azizah; Sukmawati, Sukmawati; Rahman, Safriani
Pharmaceutical Reports Vol 3, No 2 (2024): (October) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i2.310

Abstract

Qust al hindi is a plant from the Asteraceae family which has various therapeutic effects in ancient medicinal systems. This plant is used in traditional medicine in Arab countries as a stimulant, carminative, sedative and astringent. The part of Qust al hindi plant that is most often used for medicinal purposes is the dried root of the plant. This study aims to determine the content of secondary metabolites contained in the root extract of the plant Qust al Hindi. The extraction process was carried out by the soxhletation method using 96% ethanol at 70ºC, and followed by phytochemical screening. The results of the phytochemical screening of the ethanol extract of the Qust al Hindi roots positively contained alkaloids, flavonoids and terpenoids.
Evaluation of the Anti-Inflammatory Effect of Ethanol Extract of Porang Tuber (Amorphophallus muelleri Blume) on White Rats (Rattus norvegicus) Amaliah, Annisa; Rahman, Safriani; Wati, Aulia
Pharmaceutical Reports Vol 5, No 1 (2026): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v5i1.395

Abstract

Inflammation is a protective response to tissue injury aimed at neutralizing or eliminating invasive organisms triggered by physical trauma. One of the plants known for its anti-inflammatory properties is the porang tuber, which contains flavonoids. This study aimed to determine the anti-inflammatory effect and effective dosage of ethanol extract of porang tuber (Amorphophallus muelleri Blume) in male rats (Rattus norvegicus). An experimental design was employed, utilizing 20 white rats divided into five treatment groups: a negative control (1% NaCMC), a positive control (sodium diclofenac), and porang tuber ethanol extract at doses of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW. Test preparations were administered one hour before the induction of 1% carrageenan (0.1 mL, intraplantar). Paw edema volume was measured plethysmographically every 60 minutes for 6 hours. Statistical analysis, performed via one-way ANOVA followed by a Bonferroni post-hoc test, revealed no significant difference between the positive control group and the porang tuber ethanol extract groups. In conclusion, the porang tuber ethanol extract exhibits anti-inflammatory effects, with a dose of 400 mg/kgBW identified as the most effective.
Co-Authors Amaliah, Annisa Amran Nur Arini Arini Aulia Wati, Aulia Bayu Putra, Bayu Charawati, Nurul Mega Ermalyanti Fiskia Fitriana Fitriana Hasbullah, Nurhijjah Hi Amin, Rahmatia S Ika Indra Wijaya, Ika Indra Jihadi, Athira Mustakim, Putri Dwiyanti Adha NUR FADILAH Nurkhalifah ., Nurkhalifah Nurung, Ayyub Harly Polopadang, Arion Whaizer PRAHAYU, ADE CAHYA R. Rusli Rachmat Kosman, Rachmat Rahayu, Na'am Nur Azizah rahman, ismail Rahmawati . Rakhmat, Syahgita Resvani, Syahyu Saleh, Rahmat Dian Sitti Amirah Sudrianto Sudrianto, Sudrianto Sukmawati Sukmawati Virsa Handayani