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All Journal Jurnal e-Biomedik PHARMACON Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ
widdhi Bodhi
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

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Journal : PHARMACON

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UJI AKTIVITAS FAGOSITOSIS MAKROFAG EKSTRAK TANAMAN GEDI Abelmoschus Manihot (L) SEBAGAI IMUNOMODULATOR Ciptanti Prakarsa; Widdhi Bodhi; Olvie Syenni Datu
PHARMACON Vol. 13 No. 1 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.49698

Abstract

Gedi plant (Abelmoschus manihot L.) is one of the plants that contain flavonoids which have not been made into preparations for medicinal purposes. The purpose of this study was to determine the effectiveness of gedi plant extract as an immunomodulator. By looking at the activity and capacity of mouse macrophages (Rattus norvegicus) with Staphylococcus auereus bacteria in vitro. The results showed that gedi leaf extract had a significant effect on the activity and capacity of macrophages P(<0.05) which stated that gedi leaf extract had effectiveness as an immunostimulant. At a concentration of gedi plant extract of 1000 ppm, the activity and phagocytosis capacity showed the highest values, namely 87.66% and 4.23.   
Co-Authors . Fatimawali Aaltje E. Manampiring Aaltje Manampiring Angelique C. M. Tanan Axl L. Windah Billy J. Kepel Ciptanti Prakarsa Datu, Olvie Syenni Dos D. L. E. Br Siagian Fatimawali . Fona Budiarso Inggrid V. Gandu Kezia Pangemanan Marko Jeremia Kalalo Olvie Syennie Datu Sensea R. Rambitan Tiara C. Pradani