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All Journal Current Biochemistry Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing) Dharma Pengabdian Perguruan Tinggi (DEPATI) Borneo Journal of Pharmacy
Ratna Puspita
Universitas Pembangunan Nasional Veteran Jakarta
Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Antibacterial Activity of Lemongrass (Cymbopogon nardus) Ethanolic Extract Waras Nurcholis; Mira Takene; Ratna Puspita; Lisnawati Tumanggor; Eka Nurul Qomaliyah; Muhammad Maftuchin Sholeh
Current Biochemistry Vol. 6 No. 2 (2019)
Publisher : IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/cb.6.2.4

Abstract

Infectious diseases are a disease caused by bacteria such as Escherichia coli and Staphylococcus aureus. One way to overcome the disease by using antibiotics. However, wise use can lead to antibiotic resistance, so many bacteria are resistant to antibiotics. Therefore it is necessary to search the natural compounds as antibacterials, one of them by using lemongrass (Cymbopogon nardus). This study aims to determine the effectiveness of leaf extracts, stems, and roots lemongrass as antibacterial. The method used in this research is the disc method. Bacteria used are E. coli and S. aureus. The results show extracts of roots, stems, and leaf has activity against S. aureus, while E. coli shows no activity as antibacterial, it can be possible because of the different properties of the bacteria. Keywords: anti-bacteria, lemongrass, Escherichia coli, Staphylococcus aureus
PENINGKATAN PEMAHAMAN PENCEGAHAN DAN HUKUM KESEHATAN TERKAIT PANDEMI COVID-19 DI KLINIK CAHAYA KEMANG, KABUPATEN BOGOR Ratna Puspita; Isniani Ramadhani Sekar Prabarini; Erna Harfiani; Putra Sang Fajar El Harry
Dharma Pengabdian Perguruan Tinggi (DEPATI) Vol 2 No 1 (2022): May 2022
Publisher : Fakultas Teknik, Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (516.121 KB) | DOI: 10.33019/depati.v2i1.2607

Abstract

The spread of Covid-19 in Indonesia is still very high. One area that has a high impact is Kemang District, which is located in Bogor Regency. The Kemang District people need the right information to help maintain their health and prevent the transmission of Covid-19. Educational activities regarding Covid-19 aim to motivate the public so that they support the government's movement in breaking the chain of spread of Covid-19. The team provided educational media in the form of posters, pocket books, and videos on prevention of transmission and health laws related to Covid-19. In addition, the provision of materials online using ZOOM. The public understands that the prevention of Covid-19 transmission can be done with health protocols and increasing body resistance with a healthy lifestyle and vaccination. A healthy lifestyle includes maintaining a balanced diet with nutrition, exercise, and sleep patterns. Traditional medicines and supplements that are often consumed by the community also need to be adjusted to the needs of each individual. The public also gains insight into health laws related to Covid-19.
KAJIAN KESEDIAAN MASYARAKAT TERHADAP VAKSINASI COVID-19 DI INDONESIA: Analysis of Community Willingness to Get Covid-19 Vaccination in Indonesia Nofri Rahmadika; Ratna Puspita; Azzahra Brenda Tam; Elmiraz Takbirani
Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing) Vol. 9 No. 1 (2023): JIKep | Februari 2023
Publisher : LPPM STIKES Pemkab Jombang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33023/jikep.v9i1.1389

Abstract

Pendahuluan: Data epidemiologis menunjukkan bahwa sebagian besar populasi harus divaksinasi untuk mencapai kekebalan komunitas. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik dan kesediaan masyarakat Indonesia menerima vaksinasi COVID-19. Metode: Penelitian ini menggunakan desain studi cross-sectional pada Warga Negara Indonesia (WNI) usia 18-60 tahun. Sampel diambil dengan metode convenience sampling. Data dalam penelitian ini dikumpulkan menggunakan kuesioner anonim yang didistribusikan secara online dari tanggal 3 hingga 12 Maret 2021. Hasil: Hasil Penelitian menunjukkan dari total sample sebanyak 483 orang, mayoritas responden berjenis kelamin perempuan (71,9%), berusia 18-25 tahun (57%), tamat S1 (52%), tenaga kesahatan (59,3%), belum menikah (66,2%), berdomisili di jawa (82,7%), dan telah vaksinasi covid tahap 1 (83,5%). Hasil uji Chi-square menunjukkan adanya hubungan yang signifikan antara jenis kelamin (p = 0,015), domisili (p = 0,000), Tingkat Pendidikan (p = 0,000), pekerjaan (p = 0,000), kepemilikan asuransi (p = 0,000), riwayat vaksinasi sebelumnya (p = 0,004) dan kesediaan vaksinasi COVID-19. Sedangkan usia dan riwayat penyakit penyerta (comorbid) tidak berhubungan dengan kesediaan vaksinasi COVID-19. Kesimpulan: Adanya hubungan yang signifikan antara jenis kelamin, domisili, tenaga kesehatan, kepemilikan asuransi kesehatan, dan riwayat vaksin sebelumnya dengan kesediaan menerima vaksin COVID-19 (p <0.05) di Indonesia.
Antiproliferative Potency of God’s Crown Fruit (Phaleria macrocarpa) Extract Against Breast Cancer Cell Hasim Hasim; Yonathan Arderian Mantik; Husnawati Husnawati; Bambang Pontjo Priosoeryanto; Ratna Puspita
Borneo Journal of Pharmacy Vol. 5 No. 4 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i4.2822

Abstract

Breast cancer is a sickness caused by abnormal cell growth in the breast. Mahkota Dewa fruit or god’s crown fruit products (Phaleria macrocarpa) contain flavonoids, alkaloids, polyphenols, and tannins associated with active compounds. This work directs to influence the potency of P. macrocarpa fruit as an antiproliferative agent against breast cancer cells (MCF-7 cells). The antiproliferative potency of P. macrocarpa fruit was proved by extracting and fractionating P. macrocarpa fruit using maceration. The cytotoxicity of extracts and fractions was determined using Brine Shrimp Lethality Test (BSLT). The antiproliferative potency against MCF-7 cells was tested using the hemacytometer approach. This work demonstrates the crude ethanol extract, n-hexane fraction, ethyl acetate fraction, and water fraction. The LC50 values in crude ethanol extract, n-hexane fraction, ethyl acetate fraction, and water fraction were 13.72 ppm, 147.55 ppm, 405.81 ppm, and 149. 07 ppm severally. Phaleria macrocarpa fruit has shown antiproliferation potency against MCF-7 cells. The maximum part of crude ethanol extract antiproliferative potency (56 ppm) effectively suppressed MCF-7 cell growth by 70. 9% while doxorubicin (100 ppm) by 46. 92%. This work confirms that crude ethanol extract of P. macrocarpa fruit interacts synergistically as an antiproliferative compound against MCF-7 cells.
Co-Authors Azzahra Brenda Tam Bambang Pontjo Priosoeryanto Eka Nurul Qomaliyah Elmiraz Takbirani Erna Harfiani Hasim Hasim Husnawati, . Lisnawati Tumanggor Mira Takene Muhammad Maftuchin Sholeh Nofri Rahmadika Putra Sang Fajar El Harry Waras Nurcholis Yonathan Arderian Mantik