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All Journal Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Mitra Raflesia (Journal of Health Science) Journal of Community Service Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan
Riana Versita
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Humanities Economics, Econometrics & Finance Education Health Professions Industrial & Manufacturing Engineering Medicine & Pharmacology Nursing Public Health Social Sciences

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STUDI IN SILICO SENYAWA TUMBUHAN FAMILI ASTERACEAE SEBAGAI PENGHAMBAT ENZIM XANTIN OXIDASE Oky Hermansyah; Fadila Jeni Salsabila; Reza Pertiwi; Riana Versita; Ikhsan Ikhsan
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 7 No 2 (2022): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v7i2.2942

Abstract

Asteraceae family plants contain flavonoid and phenolic compounds which have many benefits including inhibiting the xanthine oxidase enzyme, this enzyme plays a role in the conversion of purines into uric acid. Excessive production of uric acid in the body can cause deposition in the joints which causes pain and stiffness and swelling of the joints. Inhibition of this enzyme can normalize the amount of uric acid in the body and reduce its effects. This study aims to determine the potential of Asteraceae family plants with the best inhibition of the xanthine oxidase enzyme using the in silico method with molecular docking. The potential of the compound was assessed based on the parameters of bond energy values, inhibition constants, hydrogen bonds and amino acid residues. The size of the molecular docking center in this study x= 95,226; y= 47,251; z = 112,78 with volume x, y, and z = 40. The simulation results show that the test compound that has the best bond energy value (ΔG) is myrisetin of -10.58 kCal/mol. In general, from the research results, myrisetin compounds contained in the asteraceae family of chrysanthemum plants are compounds that have the potential to be further tested in vitro or in vivo as inhibitors of the xanthine oxidase enzyme.
INCREASING COMPETENCE OF PHARMACY AND PHARMACY TECHNICAL PERSONNEL IN DETECTING HARMFUL CONTENT IN SKIN CARE PRODUCTS Riana Versita; Myran Nur Hinsany; Novi Yantih; Dwi Kurnia Putri; Dian handayani; Nori Wirahmi; Ikhsan, Ikhsan
Journal of Community Service Vol 6 No 1 (2024): JCS, June 2024
Publisher : Ikatan Dosen Menulis

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56670/jcs.v6i1.221

Abstract

Each skin care product has different active ingredients. In fact, Natural skin care products also contain their own active ingredients ingredients. The ingredients used in making skin care must pay attention to the safety of the user. This is not uncommon in skin care Products in circulation contain dangerous chemicals such as mercury, hydroquinone, speech, lead, etc. Pharmacy Technical personnel and pharmacists have an important role in this matter detecting harmful ingredients in skin care. Therefore, D3 Pharmacy Study Program, Faculty of Mathematics and Natural Sciences Bengkulu University of Science with Lentera Nakes as a form of community service, there is an online socialization of the National Pharmacy Seminar which will be held will be held on December 10, 2023 at 10.00 until it ends theme of Competency of Pharmaceutical Technical Personnel and Pharmacists in Detecting Dangerous Ingredients for Skin Care. This seminar can have a big impact on competency from the participants and understanding of dangerous ingredients in cosmetics
EVALUASI PENERAPAN KOMUNIKASI EFEKTIF TENAGA KEFARMASIAN DENGAN PASIEN DI PUSKESMAS SUKAMERINDU KOTA BENGKULU Tami; Ikhsan, Ikhsan; Riana Versita; Putri Mulya; Septi Adrianti
Mitra Raflesia (Journal of Health Science) Vol. 17 No. 1 (2025)
Publisher : LPPM STIKES BHAKTI HUSADA BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51712/40rfgp05

Abstract

merupakan faktor penting dalam membangun hubungan interpersonal yang baik, dalam dunia kesehatan komunikasi sangat diperlukan. Komunikasi yang kurang baik dapat menyebabkan terjadinya masalah dalam keselamatan pasien, sehingga komunikasi yang efektif merupakan komponen penting dalam tujuan keselamatan pasien. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana penerapan komunikasi efektif yang dilakukan tenaga kefarmasian dengan pasien di Puskesmas Sukamerindu Kota Bengkulu. Metode: Metode penelitian ini adalah survey dengan pendekatan deskriptif kuantitatif. Populasi penelitian ini adalah jumlah pasien dalam satu bulan yang paling banyak di tahun 2023 yaitu berjumlah 2.063 orang. Sampel didapatkan dengan teknik purposive sampling dengan menggunakan rumus Slovin dan didapat sampel sebanyak 95 orang. Instrumen penelitian ini menggunakan kuesioner skala likert 4 tingkatan. Hasil: Analisa data menggunakan analisis univariat dengan bantuan program microsoft exel dan IBM SPSS statistik dan didapatkan hasil, (53,7%) responden menjawab sangat baik, (44,2%) menyatakan baik, (2,1%) menyatakan cukup baik dan (0%) responden yang menyatakan tidak baik. Kesimpulan: Penerapan komunikasi efektif tenaga kefarmasian dengan pasien di Puskesmas Sukamerindu Kota Bengkulu sudah berjalan efektif dengan kategori sangat baik. Kata kunci: komunikasi efektif, tenaga kefarmasian, pasien, puskesmas sukamerindu   ABSTRACT Background: Communication is an important factor in building good interpersonal relationships. In the world of health, communication is very necessary. Poor communication can lead to problems in patient safety, so effective communication is an important component of patient safety goals. The purpose of this study is to find out how to implement effective communication between pharmaceutical personnel and patients at the Sukamerindu Health Center, Bengkulu City. \ Method: The method of this research is a survey with a quantitative-descriptive approach. The population of this study is the largest number of patients in one month in 2023, amounting to 2,063 people. The sample was obtained by the purposive sampling technique using the Slovin formula, and a sample of 95 people was obtained. Results: This research instrument uses a 4-level Likert scale questionnaire. Data analysis using univariate analysis with the help of Microsoft Excel and IBM SPSS statistical programs and obtained results, (53.7%) respondents answered very well, (44.2%) said good, (2.1%) said it was quite good, and (0%) respondents said it was not good. Conclusion:  The implementation of effective communication between pharmaceutical personnel and patients at the Sukamerindu Health Center, Bengkulu City, has been effective in the very good category. Keywords: effective communication, pharmaceutical personnel, patients, sukamerindu health center.
Uji Efek Antihiperglikemik Seduhan Daun Sirih Cina (Peperomia Pellicida) Diberikan Secara Oral Pada Mencit Jantan (Mus Musculus) Ruri Ayu Agrace; Riana Versita; Muhamad Arifin; Dwi Kurnia Putri; Dwi Dominica; Dian Handayani; Ikhsan Ikhsan
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.401

Abstract

Chinese Betel Plant (Paperomia pellucida) is an herbal plant that has benefits for treating diseases such as acne, ulcers, antidiabetic, antioxidant, anti-inflammatory, antimicrobial, and antibacterial. The content of bioactive compounds from Chinese betel include alkaloids, flavonoids, steroids, saponins, tannins, triterpenoids, and carbohydrates. The aim The purpose of this study was to determine the effect of steeping Chinese betel and on reducing blood glucose levels in male mice. This method used is an experimental method at the Pharmacology Laboratory D3 Pharmacy FMIPA Bengkulu University. The test animals used were three groups, namely the positive control treatment group that received glibenclamide, the negative control treatment group received aquadest, and the 2% Chinese betel steeping treatment group. The results showed that Chinese betel curd was reduced from 125 mg/dl to 93 mg/dl and there was no hypoglycemic decrease in blood glucose due to glibenclamide. From the results of the study it can be concluded that the administration of Chinese betel and glibenclamide steeping is effective in lowering blood glucose levels in male mice.
Co-Authors Dian Handayani Dominica, Dwi Dwi Kurnia Putri Dwi Kurnia Putri Fadila Jeni Salsabila Ikhsan Ikhsan Ikhsan Ikhsan Muhamad Arifin Mulia, Putri Myran Nur Hinsany Novi Yantih Oky Hermansyah Reza Pertiwi Ruri Ayu Agrace Septi Adrianti Tami Wirahmi, Nori