Article Per Year (5 Year)
p-Index From 2020 - 2025
3.346
P-Index
This Author published in this journals
All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Farmasi Higea Jurnal Pembelajaran dan Biologi Nukleus Jurnal Kefarmasian AKFARINDO Journal of Community Empowerment for Health Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Abdi Insani Konservasi Hayati Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Ilmiah Pharmacy Jurnal Pharmacopoeia Proceeding of Bengkulu International Conference on Health Bencoolen Journal of Pharmacy Rafflesia Journal of Natural and Applied Sciences (RJNAS) Jurnal Vokasi Keperawatan (JVK) Medical Sains : Jurnal Ilmiah Kefarmasian
Oky Hermansyah
Prodi D3 Farmasi FMIPA Universitas Bengkulu
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
Penetapan Kadar Vitamin C Buah Belimbing Wuluh Muda (Averrhoa bilimbi L.) dengan Metode Spektrofotometri UV-Vis Suci Rahmawati; Anisa Lathifah Fauziah; Maiyulis Maiyulis; Ikhsan Ikhsan; Oky Hermansyah
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 3, No 2 (2022): Juli
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v3i2.9327

Abstract

ABSTRAKPenelitian ini bertujuan untuk mengukur kadar vitamin C pada buah belimbing wuluh (Averrhoa bilimbi L.) muda dengan menggunakan Spektrofotometri UV-Vis. Sampel yang digunakan pada penelitian ini adalah buah belimbing wuluh yang berumur 14 hari. Teknik pengambilan sampel yang digunakan adalah simple random sampling. Penetapan kadar vitamin C 50 g sampel buah belimbing wuluh dilakukan dengan menggunakan Spektrofotometri UV-Vis pada rentang panjang gelombang 200-400 nm. Penentuan kurva kalibrasi ditetapkan dari nilai absorban larutan baku vitamin C pada kosentrasi 5 ppm, 10 ppm, 15 ppm, 20 ppm, dan 25 ppm. Hasil penelitian diperoleh panjang gelombang maksimum larutan baku vitamin C adalah 266,1 nm dan absorban sampel 0,846. Dari penetapan kurva kalibrasi diperoleh persamaan regresi y = 0,0616x + 0,0865 dengan nilai r sama dengan 0,986. Dari hasil perhitungan dapat disimpulkan bahwa kadar Vitamin C pada buah belimbing wuluh muda adalah 0,0616%. Kata kunci : Vitamin C; Belimbing Wuluh; Averrhoa bilimbi L.; Spektrofotometri UV-Vis. ABSTRACTThis study was aimed to determine of vitamin C concentration in young bilimbi (Averrhoa bilimbi L.) fruit with use UV-Vis spectrophotometry. The sample that used in this study was bilimbi fruit with the aged 14th days. The sampling technique used was simple random sampling. Determination of vitamin C concentration in 50 g of samples was carried out using UV-Vis spectrophotometry in the wavelength range in 200-400 nm. The calibration curve was determined from the absorbance value of standard vitamin C solution at concentrations of 5 ppm, 10 ppm, 15 ppm, 20 ppm, and 25 ppm. The results were showed that the maximum wavelength of vitamin C standard solution in 266.1 nm and the absorbance of the sample was 0.846. By determination of the calibration curve was obtained regression equation y = 0.0616x + 0.0865 with r value 0.986. This result it can be concluded that the concentration of Vitamin C in young bilimbi fruit was 0.0616%. Keywords : Vitamin C; Bilimbi fruit; Averrhoa bilimbi L.; UV-Vis Spectrophotometry
EFEKTIVITAS ANTIHIPERGLIKEMIK PADA KELINCI JANTAN DARI EKSTRA ETANOL BUNGA TELANG (Clitoria Ternatea) riana Versita; Nori Wirahmi; Nova Yustisia; Oky Hermansyah
Jurnal Ilmiah Pharmacy Vol 9, No 1 (2022)
Publisher : Sekolah Tinggi Kesehatan Al-Fatah Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52161/jiphar.v9i1.389

Abstract

Telang flower plant (Clitoria ternatea) is a leguminous plant belonging to the Fabaceae family, containing bioactive compounds that are useful for treatment. Its ability as a biologically active compound gives a great role to human interests. Phenolic compounds have a positive correlation with antioxidant activity, so that polyphenols are probably the compounds that have the most potential to contribute anti-radical activity in telang flower. Telang flower extract has many properties so it is used as a traditional medicine for several diseases. A number of studies have shown that flavonoids have antiviral, anti-allergic, antiplatelet, antidiabetic, diuretic, anti-inflammatory, antitumor, and antioxidant activities. The phytochemical content of telang flower which is efficacious as antidiabetic / antihyperglycemic is saponins and flavonoids. Based on this, a preliminary study was conducted to determine the effectiveness of ethanol extract of telang flower (Clitoria ternatea) against antihyperglycemic in male rabbits. This type of research is a laboratory experiment. Telang flower powder simplicia (Clitoria ternatea) was extracted using the maceration method. Telang flower (Clitoria ternatea) ethanol extract was made in 3 concentrations, namely 2%, 3% and 4%. Antohyperglycemic effectiveness test used 3 groups, namely negative control (without treatment), positive control (Glibenclamide), ethanol extract of telang flower (Clitoria ternatea) 2%, 3% and 4%, against 4 white rabbits weighing 3-3.5 kg and given sucrose, carried out until the 8th day. The data were statistically processed using One Way ANOVA (Analysis Of Variant). In conclusion, giving ethanol extract of telang flower (Clitoria ternatea) with concentrations of 2%, 3%, and 4% at 60 minutes gave an effective and significant reduction in blood glucose levels compared to negative control and positive control.
STUDI IN SILICO SENYAWA TUMBUHAN FAMILI ASTERACEAE SEBAGAI PENGHAMBAT ENZIM XANTIN OXIDASE Oky Hermansyah; Fadila Jeni Salsabila; Reza Pertiwi; Riana Versita; Ikhsan Ikhsan
Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Vol 7 No 2 (2022): Pharma Xplore : Jurnal Sains dan Ilmu Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jpx.v7i2.2942

Abstract

Asteraceae family plants contain flavonoid and phenolic compounds which have many benefits including inhibiting the xanthine oxidase enzyme, this enzyme plays a role in the conversion of purines into uric acid. Excessive production of uric acid in the body can cause deposition in the joints which causes pain and stiffness and swelling of the joints. Inhibition of this enzyme can normalize the amount of uric acid in the body and reduce its effects. This study aims to determine the potential of Asteraceae family plants with the best inhibition of the xanthine oxidase enzyme using the in silico method with molecular docking. The potential of the compound was assessed based on the parameters of bond energy values, inhibition constants, hydrogen bonds and amino acid residues. The size of the molecular docking center in this study x= 95,226; y= 47,251; z = 112,78 with volume x, y, and z = 40. The simulation results show that the test compound that has the best bond energy value (ΔG) is myrisetin of -10.58 kCal/mol. In general, from the research results, myrisetin compounds contained in the asteraceae family of chrysanthemum plants are compounds that have the potential to be further tested in vitro or in vivo as inhibitors of the xanthine oxidase enzyme.
EDUKASI PEMBUATAN JAMU YANG BAIK DAN AMAN PADA KELOMPOK JAMU GENDONG DI KOTA BENGKULU Suci Rahmawati; Nori Wirahmi; Camelia Dwi Putri Masrijal; Rose Intan Permasari; Oky Hermansyah; Samwilson Slamet
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 6, No 7 (2023): Martabe : Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v6i7.2252-2256

Abstract

Usaha Jamu Gendong (UJG) is a herbal medicine business carried out by individuals using traditional medicine ingredients in the form of fresh liquid to be sold directly to consumers. This service activity was aimed to increasing knowledge and providing skills on how to make good and safe jamu for UJG group in Bengkulu City. This activity was carried out on October 22, 2022 with 20 participants. This service activity is carried out using discussion and demonstration methods. Evaluation of activities is carried out by giving questionnaire sheets given before and after the activity. The results of the questionnaire evaluation obtained that the average score of 20 participants before and after the activity was 90.6 and 99.2, respectively. From the implementation of the activities, it can be concluded that there is an increase in the knowledge of the herbal medicine group regarding how to make good and safe traditional medicines.
TRANSDERMAL PATCH FORMULATION OF NUTMEG EXTRACT WITH HPMC (HYDROXY PROPYL METHYL CELLULOSE) AND EC ETHYL CELLULOSE (EC) AS POLYMERS Suci Rahmawati; Yetti Purnama; Kurnia Dewiani; Oky Hermansyah; Nizella Syaenri; Sari Surya Guma Sri; Elda Jumiati
Proceeding B-ICON Vol. 2 No. 1 (2023): Proceeding of The 3rd Bengkulu International Conference on Health (B-ICON 2023)
Publisher : Poltekkes Kemenkes Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33088/bicon.v2i1.160

Abstract

Nutmeg seed extract (Myristica fragrans Houtt) contains myristicin which have been an anti-inflammatory effect. Nutmeg seed extract is formulated into transdermal patch to avoid the first pass effect. This study was aimed to determine the best nutmeg extract patch transdermal formula using HPMC and EC as polymers. In this study, nutmeg extract was obtained by kinetic maceration method using 96% ethanol. The patch formula was designed into two formulas that have different types of polymer with a concentration of 4.5%, namely FP1 with HPMC polymer and FP2 with EC polymer. Patches that were evaluated for physical properties included organoleptics, weight uniformity, patch thickness, folding resistance test, drying shrinkage, absorbency test and pH. The results showed that FP1 had good organoleptic (elastic shape and even brown color); Uneven weight and thickness (SD < 0.05); Folding endurance test of 300 X; drying shrinkage 25%; absorption capacity of 8.1% and pH 6. Meanwhile, FP2 appears to have poor organoleptic properties (wrinkled shape and uneven brown color; uneven weight (SD < 0.05); uneven thickness (SD > 0.05); test folding resistance of 100 X, drying shrinkage 22.5%; absorption capacity of 20.2% and pH 6. In this study it can be concluded that FP1 with HPMC was the best formula for transdermal patch containing ethanol extract of nutmeg seeds.
TESTING THE ACTIVITY AND FORMULATION OF NATURAL HAND SOAP BASED ON NATURAL SURFACTANTS OF LERAK FRUIT (Sapindus rarak DC.) AGAINST Staphylococcus aureus Rose Intan Perma Sari; Natasha Ardinata; Oky Hermansyah; Suci Rahmawati; Camelia Dwi Putri Masrijal
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 1 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i1.1151

Abstract

Lerak (Sapindus rarak DC.) is a fruit belonging to the Sapindaceae family that usually grows in tropical forests. Lerak fruit flesh contains the main active compound, saponin. Saponin is a natural surfactant with foaming and emulsifying properties. The use of synthetic surfactants in the manufacture of hand soap sold on the market can have negative impacts, such as irritation and denaturation of proteins in the outer epidermis layer in humans if exposed too often. This study aimed to determine whether lerak can be formulated into natural hand soap as a natural surfactant and determine its antibacterial activity against Staphylococcus aureus bacteria. Lerak fruit solutions were prepared using a maceration method. The resulting solution was then formulated into hand soap at concentrations of 10%, 30%, and 50%. The evaluation of the natural hand soap preparation from the lerak fruit included organoleptic evaluation, homogeneity, pH, viscosity, foam height, and antibacterial activity against Staphylococcus aureus bacteria using the disc diffusion method. Based on the research results, Lerak Fruit (Sapindus rarak DC.) can be formulated as a natural surfactant in hand soap at concentrations of 0%, 10%, 30%, and 50%. Based on the evaluation of the physical properties in the foam height test, F1, F2, and F3 met the requirements, whereas F0 did not meet the requirements in the foam stability test because it did not contain lerak fruit extract, so no foam formed ...
A FORMULASI GEL DARI EKSTRAK ETANOL 96% DAUN CENGKEH (Syzygium aromaticum L.) Meva Parasari; Rose, Rose Intan Perma Sari; Farid; Nori Wirahmi; Oky Hermansyah
Jurnal Kefarmasian Akfarindo Vol 8 No 2 (2023)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.vi0.246

Abstract

Daun cengkeh merupakan bagian dari tanaman cengkeh yang jarang sekali dimanfaatkan berbanding sebaliknya dengan bunga cengkeh yang lebih dominan digunakan. Daun cengkeh mengandung komponenfenolik yang tinggi yaitu senyawa eugenol 70%-80% senyawa ini bersifat antibakteri. Tujuan penelitian ini adalah untuk mengetahui formulasi sediaan gel dari ekstrak etanol 96% daun cengkeh (Syzygium aromaticumL.) dan untuk melihat karakteristik dari sediaan gel ekstrak etanol 96% daun cengkeh (Syzygium aromaticumL.). Pembuatan ekstrak etanol 96% daun cengkeh menggunakan metoda maserasi. Sediaan gel dibuat dengan variasi konsentrasi ekstrak F0 (0%), F1 (10%), F2 (20%), F3 (30%). Selanjutnya dilakukan evaluasi sifat fisik meliputi uji organoleptis, uji homogenitas, uji pH, uji daya sebar, uji viskositas, dan uji stabilitas yang dilakukan selama 4 minggu. Hasil pengujian randemen ekstrak yang diperoleh adalah 14,37%. Uji pH menunjukkan gel memiliki rata-rata pH berkisar antara 4,62 - 6,01; uji daya sebar berkisar antara 5,6-7 cm; uji viskositas berkisar antara 6.256,45 – 8.232,63 cps; dan uji stabilitas yang dilakukan pada suhu 25oC–30oC selama 4 minggu menunjukkan sediaan gel stabil.
DOCKING MOLECULAR SENYAWA PADA TANAMAN FAMILI APIACEAE SEBAGAI PENGHAMBAT ENZIM XANTHINE OXIDASE Oktaviani, Tiara; Hermansyah, Oky; Ikhsan, Ikhsan; Rahmawati, Suci; Wirahmi, Nori
Jurnal Farmasi Higea Vol 16, No 1 (2024)
Publisher : STIFARM Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52689/higea.v16i1.593

Abstract

Asam urat merupakan produk metabolisme dari purin yang dikonversi oleh enzim xanthine oxidase didalam tubuh. Peningkatan kadar asam urat dalam darah karena metabolisme purin yang berlebihan dapat mengakibatkan penumpukan kristal monosodium urat pada persendian yang memicu terjadinya  penyakit gout. Tujuan penelitian ini adalah untuk memprediksi potensi senyawa aktif pada herbal famili apiaceae yang dapat menghambat kerja enzim xanthine oxidase. Penelitian ini dilakukan secara in silico dengan menggunakan aplikasi Autodock Tools 1.5.6. Docking molecular dilakukan dengan ukuran pusat penambatan molekul pada x = 95,226; y = 47,251; z = 112, 78 dengan volume x, y, dan z = 40. Struktur kristal enzim xanthine oxidase dengan kode 3BDJ sebagai makromolekul dan sebagai ligan uji 10 senyawa aktif Famili Apiaceae. Dari hasil penelitian secara in silico didapatkan bahwa senyawa aktif pada tanaman seledri (Apium graveolens) yaitu apigenin memiliki potensi sebagai anti asam urat karena dari hasil simulasi menunjukkan bahwa senyawa ini memiliki nilai energi ikatan -10,28 dimana nilainya lebih baik dibandingkan dengan ligan uji lainnya termasuk pada senyawa pembanding alupurinol,  nilai Ki-nya 29,31nM, memiliki 2 ikatan hidrogen dan terikat pada 10 residu asam amino.
A TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN INFORMASI OBAT (PIO) DI PUSKESMAS SAWAH LEBAR KOTA BENGKULU Rose, Rose Intan Perma Sari; Yumita, Yumita; Hermansyah, Oky; Khasanah, Heti Rais
BENCOOLEN JOURNAL OF PHARMACY Vol. 3 No. 1 (2023): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v3i1.27418

Abstract

Abstrak: Puskesmas merupakan fasilitas pelayanan tingkat pertama yang paling dekat dengan masyarakat. Pelayanan Informasi Obat (PIO) yang diberikan di Puskesmas oleh tenaga farmasi yang berkaitan dengan penggunaan obat secara tepat, aman dan rasional bertujuan untuk mencegah terjadinya medication error dalam penggunaan obat. Kepuasan pasien merupakan salah satu tolak ukur yang digunakan untuk mengukur keberhasilan layanan kefarmasian. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien terhadap pelayanan informasi obat berdasarkan aspek kehandalan (reability), ketanggapan (responsiveness), jaminan (assurance), empati (emphaty),dan penampilan (tangible) di Puskesmas Sawah Lebar Kota Bengkulu. Penelitian ini merupakan penelitian deskriptif yang dilakukan dengan cara membagikan kuesioner kepada responden. Sampel pada penelitian ini sebanyak 85 responden yang diperoleh dengan menggunakan teknik purposive sampling. Hasil penelitian menunjukan bahwa tingkat kepuasan pasien terhadap pelayanan informasi obat berdasarkan aspek kehandalan kategori puas (74,56%), aspek ketanggapan kategori puas (80,06%), aspek empati kategori puas (80,94%), aspek bukti fisik kategori puas (75,24%), dan aspek jaminan kategori puas (73,09%). Hasil data dapat disimpulkan bahwa tingkat kepuasan pasien terhadap pelayanan informasi obat berdasarkan lima aspek dimensi pelayanan adalah puas (76,78%). Kata Kunci: Kepuasan pasien, Pelayanan Informasi Obat, Puskesmas
STUDI IN SILICO SENYAWA AKTIF PADA FAMILI ZINGEBRACEAE SEBAGAI TERAPI ANTI ASAM URAT Hermansyah, Oky; Azkiyah, Fadhilah Zayyin; Rahmawati, Suci; Sari, Rose Intan Perma; ikhsan, ikhsan; Husna, Syarifatul
BENCOOLEN JOURNAL OF PHARMACY Vol. 3 No. 1 (2023): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v3i1.27458

Abstract

Asam urat adalah hasil terakhir purin dalam tubuh. Namun jika jumlahnya berlebih didalam darah akan mengakibatkan berbagai penyakit seperti radang sendi dan rematik. Penelitian ini bertujuan untuk mengetahui apakah senyawa tumbuhan pada famili zingiberaceae berpotensi sebagai obat anti asam urat melalui penghambatan terhadap enzim xanthine oxidase. Penelitian ini dilakukan secara in silico dengan simulasi docking molekuler, aktifitas senyawa terhadap enzim xanthine oxidase dilihat melalui nilai energi ikatan (), konstanta inhibisi (Ki), ikatan hidrogen yang terbentuk, dan residu asam amino yang terikat. Ukuran pusat penambatan molekul pada penelitian ini x = 95,226; y =47,251; z = 112,78 dengan volume x, y, dan z = 40. Hasil simulasi menunjukkan bahwa senyawa tanaman dengan nilai energi ikatan () terbaik yaitu Pinostrobin sebesar -10.35 Kkal/mol, nilai Ki 26.11 µM, memiliki 2 ikatan hidrogen dengan makromolekul dan terikat dengan 11 residu asam amino. Secara umum senyawa tanaman famili zingiberaceae berpotensi sebagai obat anti asam urat dengan penghambatan terhadap enzim xanthine oxidase
Co-Authors : Samwilson Slamet, : Samwilson Andini, Vicka Anisa Lathifah Fauziah Arinda Nur Cahyani Ashar Muda Lubis Azkiyah, Fadhilah Zayyin Camelia Dwi Putri Masrijal Camelia Dwi Putri Masrijal Delyvia Clara Gita Dwi Kurnia Putri Dwi Putri Masrijal, Camelia Dwi Retnowati Elda Jumiati Evi Maryanti Fadila Jeni Salsabila Farid Fitri, Sabrina Hidayah, Thoriqul Husna, Syarifatul Ikhsan Ikhsan Ikhsan Ikhsan Ikhsan Ikhsan Ikhsan Intan Permasari, Rose Khasanah, Heti Rais Komala, Encik Putri Ema Kurnia Dewiani Maiyulis Maiyulis Maryana, Dina Mashudi Mashudi Masrijal, Camelia Dwi Putri Meva Parasari Monalisa, Shelyn Puteri Morin Anggrainy Nabella, Inastia Natasha Ardinata Nizella Syaenri Nova Yustisia Oktaviani, Tiara Patmawati, Aprisa Riski Permasari, Rose Intan Putri, Elsa Lolita Putri, Mutiara Wulandareka Joliet Rahmadhani, Aliyah Rahmah, Anggi Apria Faradisya Reza Pertiwi Riana Versita Risky Hadi Wibowo ROBY SETIAWAN Rose Intan Perma Sari Rose Intan Perma Sari Rose Intan Perma, Sari Rose, Rose Intan Perma Sari Salamet, Samwilson Sari Surya Guma Sri Sari, Rose Intan Perma Sarmubella, Deka Septiani, Nadia Sipriyadi Suci Rahmawati Suci Rahmawati, Suci Taurina, Hilda Versita, Riana Wahid, Muhammad Ali Ashar Wasalamah, Bardah Wibowo, Risky Hadi Wirahmi, Nori Yetti Purnama Yetti Purnama Yoravika Dwiwibangga yumita, yumita