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All Journal Jurnal Kesehatan Lingkungan indonesia Jurnal Ilmu Dasar Jurnal Natur Indonesia e-Journal Pustaka Kesehatan Althea Medical Journal Indonesian Journal of Urology Journal of Agromedicine and Medical Sciences MNJ (Malang Neurology Journal) Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Profesi Medika: Jurnal Kedokteran dan Kesehatan Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Majalah Kedokteran Andalas ISM (Intisari Sains Medis) : Jurnal Kedokteran Journal of Health Sciences Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Berkala Penelitian Hayati JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Indonesian Journal of Cancer CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Makara Journal of Health Research
Heni Fatmawati
Departemen Radiologi, Fakultas Kedokteran Universitas Jember, Jalan Kalimantan 37 Kampus Tegal Boto, Jember, Jawa Timur 68121
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Control & Systems Engineering Dentistry Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Althea Medical Journal

 1 
Correlation between Vertebral Slippage in Spondylolisthesis with Ligamentum Flavum Thickening in Dr. Soebandi Hospital, Jember, East Java, Indonesia Heni Fatmawati; Alvin Candra; Nindya Shinta Rumastika; Al Munawir; Muhamad Hasan; I Nyoman Semita
Althea Medical Journal Vol 10, No 1 (2023)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v10n1.2794

Abstract

Background: Spondylolisthesis is a vertebral slip condition that compromises the body’s axial alignment and structures such as ligamentum flavum. The ligamentum flavum thickening may play a role in spondylolisthesis. The purpose of this study was to investigate the correlation between the slippage of vertebral body (spondylolisthesis) with ligamentum flavum thickening as a tissue response regarding increased mechanical stress.Methods: An analytical retrospective radiological observational was used a cross-sectional study from the results of MRI examination in Dr. Soebandi Hospital, Jember, Indonesia, collected from 2018-2021 using the simple random sampling method. Ligamentum flavum thickness and the degree of vertebral slip were measured using T2-weighted MR imaging and the correlation was analyzed using Fisher’s exact test. Results: Of 102 spondylolisthesis data records, 34 were taken, being female was the most prevalent cases in the age group above 60 years, with the most vertebral segment shift occurring at the L4–L5 level. There was a significant correlation. (p = 0.02; RR = 4.8) between ligamentum flavum thickening and vertebral slip in spondylolisthesis. Conclusion: The significant correlation between ligamentum flavum thickening and vertebral slip in spondylolisthesis suggest that mechanical stress has caused spondylolisthesis, by inducing chronic inflammation that results in hypertrophy of ligamentum flavum. Lumbar segmental instability due to spondylolisthesis is a factor contributing to the development of ligamentum flavum hypertrophy.
Severity of White Matter Lesions Correlate with Small Vessel Ischemic Stroke Zahirah, Mutiara; Fatmawati, Heni; Wiryaning Putri, Komang Yunita
Althea Medical Journal Vol 11, No 4 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n4.3338

Abstract

Background: Stroke is the third leading cause of death globally. White matter lesions (WMLs) are often observed on brain imaging such as magnetic resonance imaging (MRI) in healthy elders and are considered as stroke predictors. Increased WMLs volume also affects small vessel stroke with worse disability. This study aimed to explore the correlation between WMLs severity and small vessel stroke subtype in acute ischemic stroke patients.Methods: A cross-sectional descriptive study was conducted using medical record data from June 2018 to October 2022. Simple randomized sampling was used, including stroke patients at Siloam Hospital, Jember. The Fazekas scale categorized WMLs, and magnetic resonance angiography (MRA) confirmed small vessel stroke etiology-based subtype. Two-tailed Spearman's Rank-Order Correlation Coefficient test was employed to describe the relationship between WMLs severity and small vessel stroke subtype. Results: From a total of 65 acute ischemic stroke patients, 39 patients were included, predominantly females (62%), aged less than 55 years old (44%) with a history of hypertension (54%) and diabetes mellitus (59%). Small vessel stroke subtype was found in 64% of patients. There was a positive correlation between WMLs and the small vessel stroke subtype in acute ischemic stroke patients (p=0.02), suggesting that a higher Fazekas scale correlated with the small vessel subtype.Conclusion: The higher the severity of WMLs, the greater the correlation with small vessel stroke subtype. Early detection of small vessel ischemic stroke in patients with severe WML may contribute to early diagnosis and prompt treatment of ischemic stroke. 
Co-Authors A Rudijanto Adji, Novan Krisno Adrian Wibisono Ahmad Rudijanto Al Munawir Ali Santosa Alvin Candra Ancah Caesarina Novi Marchianti Angga Mardro Raharjo Annisa Sarfina Djunaedy Antonius Dwi Saputra Antonius G Santoso Antonius Gunawan S Azham Purwandhono Azham Purwandhono Bagus Hermansyah Brillian Adexa Yudinda Cahyana, Nugraha Wahyu Candra Bumi Candra Bumi Celly Afifah Pramono Cholis Abrori, Cholis Cynthia Parasetiayu Ariesty Desie Dwi Wisudanti Diana Chusna Mufida Dion Krismashogi Dharmawan Dita Diana Parti Edi Junaidi Elly Nurus Sakinah, Elly Nurus Emilia Puspita Sari Endang SW Erma Sulistyaningsih Ghani Silahudin Habibi, Ali Hairrudin Hairrudin Hantonius Hantonius Hendiadi, Bagus Sedya I Nyoman Semita Ida Srisurani Wiji Astuti Ika Aulia Kurniasari Ika Rahmawati Sutejo Irawan Fajar Kusuma Jauhar Firdaus Labibah, Zhafirah Rana Lailatul Maghfiroh M Rasjad Indra Made Devi Desyana Arisandi Muhamad Hasan Muhammad Afiful Jauhani Muhammad Rasjad Indra Ni Made Trismarani Sultradewi Kesuma Nindya Shinta Rumastika Nugraha Wahyu Cahyana Pattipeilohy, Florence Putri, Komang Yunita Wiryaning Putu Ayu Laksmi Lestari Rifaldy Nabiel Erisadana Rizsa Aulia Danesty S Satuman Sabila, Selma Naf’an Santoso, Antonius G Satuman Satuman septa surya wahyudi, septa surya Sofi Aliyatul Himah Sugiyanta Sugiyanta Syafa, Nahdah Ardelia Ulfa Elfiah Wiryaning Putri, Komang Yunita Wiwien Sugih Utami Yehuda Tri Nugroho Supranoto Yoga Setyo Yuli Hermansyah Yunita Armiyanti Zahirah, Mutiara