Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Indonesian Journal of Pharmaceutical Science and Technology Empowerment: Jurnal Pengabdian Masyarakat
Teuku Baihaqi Septiady
Universitas Muhammadiyah Sumatera Utara
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Transportation Veterinary Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
In Silico Study of Cembranoid-Type Diterpene Targeting Kirsten Rat Sarcoma Virus (KRAS) Gene in Lung Cancer Teuku Baihaqi Septiady; Muhammad Rafli Hidayatullah; Ainur Rofiq; Afifah Endah Dwi Purianti; Indyra Mahrani Lubis; Nesya Alya Fayyaza; Humairah Medina Liza Lubis
Indonesian Journal of Pharmaceutical Science and Technology Suppl. 4, No. 1 (2022)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v1i1.42821

Abstract

Lung cancer is genetic changes in the V-Ki-ras2 gene Kirsten rat sarcoma viral oncogene homolog(KRAS), which is involved in signaling pathways related to proliferation, cell differentiation, andapoptosis. Point mutations in the KRAS gene were detected in 15% to 20% of all Non-Small Cell LungCarcinoma (NSCLCs) and about 30% of lung adenocarcinomas, with the most common mutation beingat codon 12. This study aimed to determine the binding reaction between diterpene-type cembranoidcompounds from tobacco leaves (Nicotiana tabacum L.) and KRAS in human lung cancer. We foundthe presence of a cembranoid-type diterpene active compound in the form of thunbergol (C20H34O)with Gas Chromatography and Mass Spectroscopy (GC-MS) examination. Based on the resultsof molecular docking, it was found that the diterpene-type cembranoid ligand binds to the KRASreceptor with a yield of G -7.0 kcal/mol, pKi 7.35 M, one hydrogen bond with type ILE36 (1,937 Å).In conclusion, diterpene-type cembranoid can be considered an anticancer compound because of themolecular interaction with cembranoid-type diterpene through cell proliferation and differentiationpathways, as well as apoptosis.
Optimalisasi Strategi Operasional “Safe Motherhood dan Childhood Survival” dengan Pendekatan Penilaian Status Gizi Humairah Medina Liza Lubis; Bunail Isna Alfarisi; Tegar Alamsyah; Widya Yustika; Teuku Baihaqi Septiady; Aisyah Salsabila; Raihana Zavira; Rahmah Filzah; Annisa Rifqa Hestiana
Empowerment: Jurnal Pengabdian Masyarakat Vol. 2 No. 5 (2023): SEPTEMBER 2023
Publisher : Pusat Riset Manajemen dan Publikasi Ilmiah Serta Pengembangan Sumber Daya Manusia Sinergi Cendikia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55983/empjcs.v2i5.416

Abstract

Nutritional status is the state of the body due to food consumption and nutrient utilization that can be distinguished between poor, less, good, and more nutritional status which can have an impact on morbidity and mortality. An important factor in the incidence of infant morbidity and mortality is low birth weight due to the consumption of unhealthy foods during pregnancy and the period of supplementary feeding. This community service aims to determine the nutritional status of toddlers based on anthropometric measures. The service method is carried out through counseling, filling out questionnaires, and anthropometric measurements of infants aged < 1 year using scales and an infantometer. Assessment of children's nutritional status based on weight to height is severely wasted: <-3 SD, underweight: -3 SD to <-2 SD, normal: -2 SD to +1 SD, risk of overweight: >+1 SD to +2 SD, overweight: >+2 SD to +3 SD, and obesity: >+3 SD. The results of the service were obtained from 32 babies who were anthropometrically 24 children with normal status, 2 children were obese and 6 children were underweight.
Co-Authors Afifah Endah Dwi Purianti Ainur Rofiq Aisyah Salsabila Annisa Rifqa Hestiana Bunail Isna Alfarisi Humairah Medina Liza Lubis Indyra Mahrani Lubis Muhammad Rafli Hidayatullah Nesya Alya Fayyaza Rahmah Filzah Raihana Zavira Tegar Alamsyah Widya Yustika