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All Journal Dentika Dental Journal ODONTO Dental Journal Dental Journal (Majalah Kedokteran Gigi) E-Prodenta Journal of Dentistry Sinnun Maxillofacial Journal eJournal Kedokteran Indonesia Cakradonya Dental Journal Odonto dental journal
Yuanita Lely Rachmawati
University Of Brawijaya
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Public Health

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Journal : Odonto dental journal

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Binahong leaf extract (anredera cordifolia) mucoadhesive patch as an alternative therapy for recurrent aphthous stomatitis Lisa Oktaviona Saputri; Dania Tamimmi; Renita Rahma Chairu Nisa; Nabila Hardina Rossah; Afsal Unnisa Rachman; Yuanita Lely Rachmawati
Odonto : Dental Journal Vol 9, No 2 (2022): December 2022
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (382.279 KB) | DOI: 10.30659/odj.9.2.168-182

Abstract

Background: Recurrent Aphthous Stomatitis (RAS) is one of the most common oral diseases of all ages. There has been no study that defines the leading cause of RAS. The utilization of binahong leaves (Anredera cordifolia) can be beneficial for the treatment of RAS as it acts as an anti-inflammatory and accelerates the proliferation of fibroblasts. The combination between binahong leaves and the mucoadhesive patch will increase the effectiveness of RAS treatment.Method: Literature study through PubMed and Google Scholar databases was conducted using PRISMA flow chart looking for the efficacy of binahong leaves (Anredera cordifolia) for mucosa wound healing and mucoadhesive patches for the treatment of RAS.Result: The search results found 31 articles that met the criteria for analysis. Flavonoids and saponins in binahong leaves extract act as an anti-inflammatory and increase the proliferation of wound healing. Mucoadhesive patch formulation can increase the effectiveness of RAS treatment on the mucosa.Conclusion: Binahong leaves extract in the form of mucoadhesive patches can be used as an alternative treatment for Recurrent Aphthous Stomatitis.
Co-Authors Afsal Unnisa Rachman Ambar Puspitasari Amira Rachmatillah Amirah Nanda Herlambang Anestya Wibowo, Marchella Ardyarum, Mahfita Aufa Nikita, Dhea Balbeid, Merlya Bintang Vallentino Nugraha Putra Dania Tamimmi Devi Cahaya Ningtyas Diwya Nugrahini Hapsari Edina Hartami Endah Damaryanti, Endah Hamida Mahardika Ningrum Herlambang Pangestu Kartika Andari Wulan Kurniawati, Sari Lalita El Milla Lisa Oktaviona Saputri Mahardika Ningrum, Hamida Mahfita Ardyarum Marchella Anestya Wibowo Marchella Anestya Wibowo Merlya Balbeid Nabila Hardina Rossah Nahla Palupi, Dyah Nawang Pratamawari, Dyah Nawang Palupi Rachmatillah, Amira Rahmadanti, Besti Renita Rahma Chairu Nisa Viranda Sutanti Viranda Sutanti