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All Journal Jurnal Farmagazine Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Gizi Kerja dan Produktivitas Jurnal Ilmiah Agribios Journal of Pharmaceutical and Sciences.
Firman Rezaldi
Program Studi Farmasi, STIKES Bhakti Husada Mulia Madiun
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences

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UJI DAYA HAMBAT MADU HUTAN BADUY SEBAGAI SUBSTRAT PADA BUNGA TELANG (Clitoria ternatea L) MELALUI METODE BIOTEKNOLOGI FERMENTASI KOMBUCHA DALAM MENGHAMBAT PERTUMBUHAN BAKTERI PATOGEN Kusumiyati Kusumiyati; Diyan Yunanto Setyaji; M. Fariz Fadillah; Firman Rezaldi
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 11 No 2 (2022): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v11i2.109

Abstract

Telang flower (Clitoria ternatea L) fermented by kombucha is a probiotic drink produced by a consortium of bacteria and yeast. The raw material in this kombucha fermentation is in the form of telang flowers that have been cold from the previous boiling process. This study aims to determine the antibacterial activity of telang flower kombucha with different concentrations of Baduy forest honey. The concentration of Baduy forest honey consisted of 20%, 30%, and 40% (w/v) where each treatment was repeated 3 times. The positive control used in this study was kombucha made from green tea. Sterile aquadest is a treatment positioned as a negative control. The disc diffusion method is one of the methods used in antibacterial testing by measuring the diameter of the inhibition zone. Telang flower kombucha fermentation has activity as a broad-spectrum antibacterial source. This can be indicated by the potential to prevent the growth of Staphylococcus aureus, Staphylococcus epidermidis, Pseudomnonas aeruginosa, and Escherichia coli bacteria. Baduy forest honey concentration of 40% is the best concentration in fermented kombucha flower telang as an antibacterial and has the potential as the latest functional drink from fermented biotechnology products.
UJI DAYA HAMBAT Propinobacterium acnes PADA PRODUK BIOTEKNOLOGI FARMASI SEDIAAN SABUN WAJAH KOMBUCHA BUNGA TELANG (Clitoria ternatea L) Laela Febriana; R.F.X. Premihadi Putra; Firman Rezaldi; Susanti Erikania; Rina Nurmaulawati; Priyoto Priyoto
Jurnal Farmagazine Vol 10, No 1 (2023): Jurnal Farmagazine
Publisher : STF Muhammadiyah Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47653/farm.v10i1.644

Abstract

Propinobacterium acnes merupakan salah satu bakteri yang dapat menyebabkan terjadinya jerawat pada bagian wajah. Sabun wajah yang berbahan aktif larutan fermentasi kombucha bunga telang secara positif berkolerasi dalam menghambat pertumbuhan bakteri penyebab jerawat yaitu Propinobacterium acnes. Penelitian ini bertujuan untuk membuat formulasi dan sediaan sabun wajah yang berbahan aktif larutan fermentasi kombucha bunga telang pada konsentrasi 20%, 30%, dan 40%. Metode penelitian ini dilakukan secara eksperimental laboratorium yaitu dengan cara menyiapkan sediaan sabun wajah yang telah beredar dipasaran sebagai kontrol positif, membuat basis sabun wajah tanpa zat aktif sebagai kontrol negatif, dan membuat basis sabun wajah yang berbahan aktif larutan fermentasi kombucha bunga telang pada konsentrasi 20%, 30%, dan 40%. Metode difusi cakram merupakan salah satu cara untuk menghambat pertumbuhan bakteri Propinobacrterium acnes dari masing-masing sediaan sabun wajah. Analisis data yang digunakan dalam penelitian ini adalah ANOVA satu jalur dan uji lanjut berupa analisis pos hoc. Hasil penelitian ini berdasarkan uji ANOVA satu jalur dengan masing-masing nilai p yang dihasilkan kurang dari 0,05 dan juga analisis pos hoc dapat disimpulkan bahwa sediaan sabun wajah yang berbahan aktif larutan fermentasi kombucha bunga telang pada konsentrasi 40% berbeda nyata dengan konsentrasi 20% dan 30% sebagai antibakteri Propinobacterium acnes. Namun tidak berbeda nyata dengan kontrol positif. Konsentrasi 40% merupakan konsentrasi terbaik diantara dua perlakuan dan kedua pembanding baik kontrol positif maupun negatif dengan rata-rata diameter zona hambat yang dihasilkan adalah sebesar 15,60 mm dan masuk dalam kategori kuat.
UJI DAYA HAMBAT PERTUMBUHAN BAKTERI GRAM POSITIF DAN NEGATIF DARI PRODUK BIOTEKNOLOGI FARMASI DALAM BENTUK FORMULASI DAN SEDIAAN SABUN CUCI PIRING GEL KOMBUCHA BUNGA TELANG (Clitoria ternatea L) Firman Rezaldi; Rustini Rustini; Ayu Safitri; Siska Dwi Anggraeni; Aris Ma'ruf; Eman Eman; Maya Puspitasari
AGRIBIOS Vol 21 No 1 (2023): JUNI
Publisher : Program Studi Agribisnis Fakultas Pertanian

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36841/agribios.v21i1.2843

Abstract

Dishwashing gel soap made from telang flower kombucha fermented solution has the potential to inhibit the growth of gram-positive and negative bacteria. Gram-positive and negative bacteria that have been successfully inhibited by gel dish soap made from an active ingredient of telang flower kombucha fermented solution include Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Escherichia coli. This research is an experimental laboratory, namely by providing dishwashing soap that has been circulating in the market as a positive control. Making a gel hand washing soap base with an active ingredient of telang flower kombucha fermented solution at a sugar concentration of 20%, 30%, and 40% which was tested against the four test bacteria consisting of two gram-positive bacteria and 2 gram-negative bacteria using disc diffusion. The data analysis used was one-way ANOVA where the resulting P value was less than 0.05 and it can be concluded that the telang flower kombucha gel dish soap at a concentration of 40% based on further analysis in the form of a post hoc test, which is significantly different from the kombucha gel dish soap butterfly pea flower at concentrations of 20% and 30% inhibited the growth of the four test bacteria but was not significantly different from the dishwashing soap on the market as a positive control. The formulation and preparation of telang flower kombucha gel dish soap at a concentration of 40% was the best concentration in inhibiting the growth of the four test bacteria compared to concentrations of 20% and 30% and even the two comparison dish soaps.
Aktivitas Farmakologi Pada Kombucha Bunga Telang (Clitoria ternatea L) Dalam Menurunkan Kolesterol Ayam Petelur (Gallus domesticus) Dengan Metode Bioteknologi Fermentasi Muhammad Faizal Fathurrohim; Firman Rezaldi; Yuliana Kolo; Ucu Wandi Somantri; M. Fariz Fadillah; Irmawati Mathar
Jurnal Gizi Kerja dan Produktivitas Vol 4, No 1 (2023): May
Publisher : Fakultas Kedokteran Universitas Sultan Ageng Tirtayasa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62870/jgkp.v4i1.19818

Abstract

Protein hewani yang dikonsumsi secara rutin dan berlebihan dapat menyebabkan kolesterol tinggi. Penyakit kolesterol lebih dikenal dengan nama hiperkoleteromia yang dapat menyebabkan komplikasi pada kesehatan manusia. Penelitian ini bertujuan memperoleh sumber protein hewani yang rendah kolesterol. Dalam penelitian ini, 20 ekor ayam petelur yang berusia 3 bulan telah diberikan minuman kombucha bunga telang sebagai asupan. Metode penelitian ini menggunakan Rancangan Acak Lengkap dengan 4 perlakuan selama 4 minggu dengan konsentrasi gula kombucha bunga telang 20%, 30% dan 40%. Analisis data menggunakan metode ANOVA dan dilanjutkan dengan uji Duncan dengan tingkat kepercayaan 95%. Temuan penelitian menunjukkan bahwa memberikan kombucha bunga telang memiliki efek yang signifikan dalam menurunkan kadar kolesterol pada ayam petelur dan konsentrasi gula 40% pada kombucha bunga telang merupakan perlakuan yang terbaik dibandingkan dengan perlakuan lainnya sebagai antikolesterol pada ayam petelur.
Skrining Fitokimia Dan Analisis Kadar Kafein Pada Kopi Bubuk Jenis Arabika Di Kota Takengon Menggunakan Spektrofotometri Ultraviolet Muhammad Andry; Fahma Shufyani; Muhammad Amin Nasution; M. Fariz Fadillah; Ika Julianti Tambunan; Firman Rezaldi
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.176

Abstract

Background: Coffee is a type of plant that contains caffeine and can be made into a delicious drink. Currently, coffee is the world's most popular drink after water and tea. The stuay aimed was to determine the caffeine content in Arabica ground coffee circulating in the Takengon market according to Indonesian national standards (SNI 01-7152-2006). This research was experimental by taking samples purposively. The research method used was phytochemical screening, qualitative analysis, and ultraviolet spectrophotometry at a wavelength of 273nm. The specified validation parameters were precision, linearity, LOD and LOQ. The results of the phytochemical screening of sample A in the Meyer test treatment obtained negative results but the others were positive. And in sample B, all tests were positive. In the three qualitative analyses tests on samples A and B, the results were positive. The average yield of quantitative analysis in sample A was 11.632 mg once and the daily concentration was 34.897mg. while in sample B the level was 6.663 mg once and drank 19.989mg per day. Validation test results obtained linearity r2 = 0.998, LOD and LOQ namely 0.882µg/ml and 2.94µg/ml, RSD value of 1.11%. Based on the conclusion, sample A and sample B met the requirements according to SNI 2006 (50mg once and 150mg daily) and also met the requirements according to the Pharmacopoeia Edition III, namely a maximum dose of 500 mg once and 1.5g daily.
Co-Authors Aris Ma'ruf Ayu Safitri diyan Yunanto Setyaji Eman Eman Fahma Shufyani Ika Julianti Tambunan Irmawati Mathar Kusumiyati Laela Febriana M. Fariz Fadillah M. Fariz Fadillah M. Fariz Fadillah Maya Puspitasari Muhammad Amin Nasution Muhammad Andry Muhammad Faizal Fathurrohim Priyoto Priyoto R.F.X Premihadi Putra Rina Nurmaulawati Rustini Rustini Siska Dwi Anggraeni Susanti Erikania Ucu Wandi Somantri Yuliana Kolo