Mita Anggraeni, Mita
Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Udayana University

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Anti Tuberculosis Activity of Forest Kedondong (Spondias pinnata) Stembark Extract Against Multiple Drug Resistance (MDR) Strain of Mycobacterium Tuberculosis Dwija, I.B.N. Putra; Anggraeni, Mita; Ariantari, Ni Putu
BALI MEDICAL JOURNAL Vol 5 No 1 (2016)
Publisher : BALI MEDICAL JOURNAL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (265.376 KB)

Abstract

Background: Forest Kedondong (Spondias pinnata) traditionally known as “loloh cemcem” and commonly used as a chronic cough remedy. Previous research showed that methanol extract of Forest Kedondong leaves active against MDR strain of Mycobacterium tuberculosis. The aim of this study were to determine the phytochemical constituent and anti tuberculosis activity of stem bark extract of this plant against MDR strain of M. tuberculosis. Method: Coarsely powder of Forest Kedondong stem bark was extracted successively with n-hexane, chloroform and 80% ethanol. Anti tuberculosis assay of chloroform and ethanol extract was conducted using proportion method with Lowenstein-Jensen medium within 3 different concentration of extract of 1, 10, and 100 mg/mL. Activity was evaluated by inhibition of extract against M. tuberculosis growth, which was calculated by mean reduction in number of colonies on extract containing medium compared to control. Results and Discussion: Phytochemical test showed that chloroform extract contains terpenoid and flavonoids. Ethanol extract contains terpenoid, polyphenols and flavonoids. These extracts were active against MDR strain of M. tuberculosis with 100% inhibition at concentration of 100 mg/mL. Chloroform extract has higher inhibition against M. tuberculosis growth than Ethanol extract. Conclusions: These extracts were potentially developed to an anti tuberculosis constituent from natural product.
Literature Review : The Effect Of Ginger (Zingiber Officinale Var. Amarum) And Honey On Blood Pressure Reduction Luthfiyah, Fifi; Anggraeni, Mita; Wahyuningsih, Retno
Journals of Ners Community Vol 13 No 5 (2022): Jurnal of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i5.2206

Abstract

The prevalence of hypertension in NTB at 2018 was 27.8%, this figure was higher than 2013, which was 24.3%. Hypertension management can be done pharmacologically and non pharmacologically. Non pharmacological therapy can be done by consuming honey and ginger. Honey and ginger contain chemical components that can help lower blood pressure. To conduct a literature study on the effect of ginger (Zingiber officinale var. Amarum) and honey on reducing blood pressure. The literature search in this literature review was carried out using five databases with low to high quality, namely Scopus, ProQuest, Pubmed, Garuda Garba, and Google Schoolar. The keywords used are "ginger and blood pressure", "ginger and diastoleic pressure", "ginger and pulse pressure", "ginger and systolic pressure", "ginger officinale and blood pressure", "ginger officinale and diastoleic pressure", " ginger officinale and pulse pressure "," ginger officinale and systolic pressure "," honey and blood pressure "," honey and diastoleic pressure "," honey and systolic pressure ". From 10 journals that have been reviewed, all states that honey and ginger can reduce blood pressure. Honey was able to lower blood pressure with an average decrease in systolic blood pressure by 5.6 mmHg - 30.00 mmHg and a decrease in the average diastolic blood pressure by 7.3 mmHg - 13.00 mmHg, while ginger was able to lower blood pressure by an average -The decrease in systole was 4.73 mmHg - 7.7 mmHg and the decrease in diastolic blood pressure was 5.7 mmHg - 7.27 mmHg. The average dose of honey given is 30 grams - 70 grams, while the average dose of ginger is 4 grams. Form 10 journals have been reviewed, all journals stated that honey and ginger can lower blood pressure and based on all these journals it is known that honey has a greater effect on reducing blood pressure than ginger.
Literature Review : The Effect Of Ginger (Zingiber Officinale Var. Amarum) And Honey On Blood Pressure Reduction Luthfiyah, Fifi; Anggraeni, Mita; Wahyuningsih, Retno
Journals of Ners Community Vol 13 No 5 (2022): Jurnal of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i5.2206

Abstract

The prevalence of hypertension in NTB at 2018 was 27.8%, this figure was higher than 2013, which was 24.3%. Hypertension management can be done pharmacologically and non pharmacologically. Non pharmacological therapy can be done by consuming honey and ginger. Honey and ginger contain chemical components that can help lower blood pressure. To conduct a literature study on the effect of ginger (Zingiber officinale var. Amarum) and honey on reducing blood pressure. The literature search in this literature review was carried out using five databases with low to high quality, namely Scopus, ProQuest, Pubmed, Garuda Garba, and Google Schoolar. The keywords used are "ginger and blood pressure", "ginger and diastoleic pressure", "ginger and pulse pressure", "ginger and systolic pressure", "ginger officinale and blood pressure", "ginger officinale and diastoleic pressure", " ginger officinale and pulse pressure "," ginger officinale and systolic pressure "," honey and blood pressure "," honey and diastoleic pressure "," honey and systolic pressure ". From 10 journals that have been reviewed, all states that honey and ginger can reduce blood pressure. Honey was able to lower blood pressure with an average decrease in systolic blood pressure by 5.6 mmHg - 30.00 mmHg and a decrease in the average diastolic blood pressure by 7.3 mmHg - 13.00 mmHg, while ginger was able to lower blood pressure by an average -The decrease in systole was 4.73 mmHg - 7.7 mmHg and the decrease in diastolic blood pressure was 5.7 mmHg - 7.27 mmHg. The average dose of honey given is 30 grams - 70 grams, while the average dose of ginger is 4 grams. Form 10 journals have been reviewed, all journals stated that honey and ginger can lower blood pressure and based on all these journals it is known that honey has a greater effect on reducing blood pressure than ginger.
KERAGAAN BEBERAPA GENOTIP JAGUNG PAKAN/YELLOW CORN (Zea mays L.) MUTAN KOLKISIN GENERASI M¬2 Anggraeni, Mita; Damanhuri, Damanhuri; Sugiharto, Arifin Noor
Produksi Tanaman Vol. 5 No. 3 (2017)
Publisher : Jurusan Budidaya Pertanian Fakultas Pertanian Universitas Brawijaya

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Abstract

Perakitan benih unggul jagung pada saat ini telah banyak dilakukan dimana salah satunya melalui proses mutasi buatan. Telah dilakukan penelitian yang bertujuan untuk mengetahui keragaan dan variasi dari populasi setiap perlakuan kolkisin dan individu jagung pakan/yellow corn (Zea mays L.) mutan kolkisin hasil seleksi M1. Penelitian ini dilaksanakan pada bulan Oktober 2014 – Februari 2015 di dusun Areng – Areng, kelurahan Dadaprejo, kecamatan Junrejo, Batu. Bahan yang digunakan adalah 2 galur (INC dan INF) dengan 5 perlakuan kolkisin (0 ppm, 400 ppm, 600 ppm, 0x400 ppm dan 0x600 ppm). Karakter kuantitatif yang diamati adalah tinggi tanaman, jumlah daun, panjang daun, lebar daun, umur berbunga jantan, umur berbunga betina, umur panen, panjang tongkol, bobot tongkol, bobot 100 biji, panjang stomata, lebar stomata dan bobot pipilan. Sedangkan karakter kualitatif yang diamati adalah warna biji dan bentuk permukaan biji. Hasil penelitian menunjukkan tanaman perlakuan kolkisin berbeda nyata dengan kontrol pada karakter warna biji, tinggi tanaman, jumlah daun,  panjang daun, lebar daun, panjang stomata, lebar stomata, umur berbunga jantan, umur berbunga betina, umur panen, panjang tongkol, bobot tongkol, bobot pipilan dan bobot 100 biji. Individu terpilih memiliki nilai tinggi tanaman yang tinggi, jumlah daun banyak dan berukuran panjang serta lebar, umur berbunga jantan, umur berbunga betina dan umur panen standar, tongkol panjang, bobot tongkol, bobot 100 biji dan bobot pipilan tinggi serta ukuran panjang dan lebar stomata besar.