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All Journal As-syifaa Jurnal Farmasi Jurnal Ilmiah Farmako Bahari Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Health Research
Vina Purnamasari M
Fakultas Farmasi Universitas Muslim Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Formulasi dan Evaluasi Masker Hyrogel Ekstrak Etanol Pegagan (Centella Asiatica (L). Urb) Sebagai Antiaging dengan Variasi Basis Carbopol dan HPMC Vina Purnamasari M; Nurlina Nurlina; Anita Sari Anwar
Journal of Pharmaceutical and Health Research Vol 4 No 2 (2023): June 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i2.3644

Abstract

Gotu kola ethanol extract (Centella asiaticaI (L)urb.) has very strong antioxidant activity with an IC50 value of 20.43 μg/ml which can be utilized in the development of pharmaceutical or cosmetic preparations. The purpose of this study was to formulate and evaluate a pharmacologically stable preparation of hydrogel antiaging mask of gotu kola ethanol extract (Centella asiaticaI (L)urb.). The research design used by varying the concentration of carbopol and HPMC was then carried out physical evaluations such as organoleptis, homogeneity, ph measurement, viscosity and flow type tests, adhesion tests, dispersion tests, weight and size tests of hydrogel masks, inflating power tests and shrinkage tests and stability tests. The evaluation results showed that gotu kola ethanol extract (Centella asiaticaI (L)urb.) that met the pharmaceutical stability test was formula 2 with a carbopol concentration of 1.25% and HPMC 2.25%.
Co-Authors A Hasrawati Anifatul Mu’awanah Anita Sari Anwar Aztriana Aztriana Dian Safitri Achmad Ermina Pakki Hamsinah Hamsinah Iskandar Zulkarnain Mirawati Mirawati Nurfajeriani Ulfah Nurlina Nurlina Ririn Ririn Sri Dewi Juwita Abdullah