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All Journal As-syifaa Jurnal Farmasi Jurnal Ilmiah Farmako Bahari Jurnal Riset Kefarmasian Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat Journal of Pharmaceutical and Health Research
Vina Purnamasari M
Fakultas Farmasi Universitas Muslim Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Formulasi dan Evaluasi Masker Hyrogel Ekstrak Etanol Pegagan (Centella Asiatica (L). Urb) Sebagai Antiaging dengan Variasi Basis Carbopol dan HPMC Vina Purnamasari M; Nurlina Nurlina; Anita Sari Anwar
Journal of Pharmaceutical and Health Research Vol 4 No 2 (2023): June 2023
Publisher : Forum Kerjasama Pendidikan Tinggi (FKPT)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jharma.v4i2.3644

Abstract

Gotu kola ethanol extract (Centella asiaticaI (L)urb.) has very strong antioxidant activity with an IC50 value of 20.43 μg/ml which can be utilized in the development of pharmaceutical or cosmetic preparations. The purpose of this study was to formulate and evaluate a pharmacologically stable preparation of hydrogel antiaging mask of gotu kola ethanol extract (Centella asiaticaI (L)urb.). The research design used by varying the concentration of carbopol and HPMC was then carried out physical evaluations such as organoleptis, homogeneity, ph measurement, viscosity and flow type tests, adhesion tests, dispersion tests, weight and size tests of hydrogel masks, inflating power tests and shrinkage tests and stability tests. The evaluation results showed that gotu kola ethanol extract (Centella asiaticaI (L)urb.) that met the pharmaceutical stability test was formula 2 with a carbopol concentration of 1.25% and HPMC 2.25%.
Determination of Caffeine Content in Ethanolic Extract of Robusta Coffee Beans (Coffea canephora) Using UV-Vis Spectrophotometry Vina Purnamasari; Ririn; A Hasrawati
Jurnal Riset Kefarmasian Indonesia Vol. 8 No. 2 (2026): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v8i2.936

Abstract

Caffeine is one of the main bioactive compounds in robusta coffee beans (Coffea canephora) that has potential applications in pharmaceutical and cosmetic formulations, particularly for hair growth stimulation. This study aimed to determine the caffeine content in ethanolic extract of robusta coffee beans using UV-Visible spectrophotometry. The research was conducted using an experimental laboratory design. Robusta coffee bean extract was obtained by maceration using ethanol as the solvent. Qualitative identification of caffeine was followed by quantitative analysis using UV-Vis spectrophotometry at a maximum wavelength of 273 nm. A calibration curve was constructed using standard caffeine solutions, and the caffeine content of the extract was calculated based on the linear regression equation. The results showed that the calibration curve exhibited good linearity within the tested concentration range. Quantitative analysis revealed that the caffeine content of the ethanolic extract of robusta coffee beans was 221.58 mg/g extract, which is consistent with previously reported caffeine levels in Coffea canephora. These findings confirm that robusta coffee beans are a significant natural source of caffeine and support their potential utilization as raw material for pharmaceutical and cosmetic products. This study provides quantitative data that may serve as a scientific basis for further formulation development and quality control of caffeine-containing herbal products.
Co-Authors A Hasrawati A Hasrawati Anifatul Mu’awanah Anita Sari Anwar Aztriana Aztriana Dian Safitri Achmad Ermina Pakki Hamsinah Hamsinah Iskandar Zulkarnain Mirawati Mirawati Nurfajeriani Ulfah Nurlina Nurlina Ririn Ririn Sri Dewi Juwita Abdullah