Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Jurnal Sains dan Edukasi Sains Aptekmas : Jurnal Pengabdian Kepada Masyarakat
Anggelinus Nadut
Universitas Katolik Widya Mandira Kupang
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Astronomy Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
SOSIALISASI POLA HIDUP BERSIH DAN SEHAT DALAM UPAYA PENCEGAHAN STUNTING DI DESA MANLETEN KABUPATEN BELU Anselmus Boy Baunsele; Ambrosius Faofeto; Hildegardis Missa; Aloysius Djalo; Sardina Ndukang; Anggelinus Nadut; Gerardus D. Tukan; Maximus M. Taek; Adri Gabriel Sooai
Aptekmas Jurnal Pengabdian pada Masyarakat Vol 6 No 1 (2023): APTEKMAS Volume 6 Nomor 1 2023
Publisher : Politeknik Negeri Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36257/apts.v6i1.4839

Abstract

The healty lifestyle is a habits that needs to be used as a principle of life by every people to improving the life quality especially for the health sector. The good comprehension of health can help every people for stunting prevention. Stunting is a kind of disease that caused by the poor nutrition of meals for the children for their growing period. By the community service program of public education of high nutrition food for the parents to increase the nutrition grade for these children is expected to prevent the potential for stunting in these children. In addition, this community service program give the new experience for the community to utilize the ingridients food to create the high nutrition food with low price and can produce in every household. Babanas and corn are abundantly available in Manleten Village and always consumed by the conventional processing can be produced to be a new variant of food that can be a new food reference
Profil senyawa bioaktif ekstrak etanol Grewia koordersiana Burret dan prediksi potensi hepatoprotektif secara in silico Lodowik Pote; Maximus Taek; Gertreda Latumakulita; Anggelinus Nadut
Jurnal Sains dan Edukasi Sains Vol. 9 No. 2 (2026): Jurnal Sains dan Edukasi Sains
Publisher : Faculty of Science and Mathematics, Universitas Kristen Satya Wacana, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24246/juses.v9i2p162-172

Abstract

Grewia koordersiana Burret merupakan salah satu tanaman yang berpotensi sebagai sumber senyawa bioaktif dengan aktivitas hepatoprotektif. Penelitian ini bertujuan mengidentifikasi senyawa bioaktif dalam ekstrak etanol kulit batang G. koordersiana Burret; mengevaluasi potensi interaksinya terhadap protein Cytochrome P450 2E1 (CYP2E1) melalui molecular docking; serta memprediksi sifat farmakokinetik dan toksisitas secara in silico. Identifikasi senyawa dilakukan menggunakan UPLC-QTOF-MS/MS, sedangkan molecular docking dilakukan terhadap protein CYP2E1 (PDB ID: 3E6I). Prediksi drug-likeness dianalisis menggunakan SwissADME, sementara profil ADMET dan toksisitas diprediksi menggunakan pkCSM dan ProTox-3. Hasil analisis UPLC-QTOF-MS/MS berhasil mengidentifikasi 15 senyawa bioaktif yang termasuk dalam golongan alkaloid, flavonoid, fenolik, steroid, aminoglikosida, triterpenoid, lipid, alkaloid steroidal, dan glikosfingolipid. Hasil molecular docking menunjukkan bahwa seluruh ligan membentuk ikatan hidrogen dan/atau interaksi hidrofobik dengan residu asam amino, meliputi ARG100, ARG126, ARG127, THR303, ALA299, LEU130, LEU368, CYS437, ALA438, LEU442, ARG435, dan PRO429. Hasil prediksi SwissADME menunjukkan bahwa helenalin dan senyawa nomor 11 memenuhi seluruh kriteria Lipinski sehingga berpotensi sebagai kandidat obat oral. Analisis ADMET mengindikasikan bahwa sebagian besar senyawa memiliki profil absorpsi, distribusi, metabolisme, dan ekskresi yang cukup baik, tidak bersifat mutagenik maupun hepatotoksik, serta didominasi oleh tingkat toksisitas rendah hingga sedang. Studi ini menyimpulkan bahwa ekstrak etanol kulit batang G. koordersiana Burret mengandung beragam senyawa bioaktif yang berpotensi sebagai inhibitor CYP2E1 dan bersifat hepatoprotektif. Penelitian lanjutan secara in vitro dan in vivo diperlukan untuk mengonfirmasi aktivitas biologis dan keamanan senyawa tersebut.
Co-Authors Adri Gabriel Sooai Aloysius Djalo Ambrosius Faofeto Anselmus Boy Baunsele Gerardus Diri Tukan Gertreda Latumakulita Hildegardis Missa Lodowik Pote Maximus M Taek Maximus Taek Sardina Ndukang