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All Journal SCRIPTA SCORE Scientific Medical Journal Media Dermato-Venereologica Indonesiana Journal of General Procedural Dermatology and Venereology Indonesia
Remenda Siregar, Remenda
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Health Professions Medicine & Pharmacology

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Noninvasive diagnostic modality for skin cancer Siregar, Remenda; Nurhayati, Raja; Oentari, Widyaningsih; Sari, Ari Karmila
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 5, No. 2
Publisher : UI Scholars Hub

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Abstract

Histopathological examination is the gold standard for the diagnosis of nonmelanoma and melanoma skin cancer, but it is an invasive procedure that consumes time and requires large costs. The average cure rate for skin cancer is high with early detection and appropriate treatment. This is an article review that was made through findings from several scientific articles. There are several noninvasive imaging modality choices that can be used for screening at low cost, high quality, and faster result, which includes dermoscopy, optical coherence tomography, reflectance confocal microscopy, electrical impedance spectroscopy, multispectral imaging, and SIAscopy®. These imaging modalities can assist in the detection of skin cancer using a combination of high-quality computer science, mathematics, and optics. This can improve the efficiency of diagnosis and management, reduce treatment costs, and increase patient satisfaction while utilizing teledermatology.
Management of basal cell carcinoma with excision followed by rotation advancement flap Siregar, Remenda; Puspita, Fitri; Oentari, Widyaningsih; Sari, Ari Karmila
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 5, No. 3
Publisher : UI Scholars Hub

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Background: Basal cell carcinoma (BCC) is the most common malignant skin tumor and is derived from pluripotent cells in the basal layer of the epidermis. One of the BCC management options is surgery followed by a skin flap to close the wound defect. Case Illustration: We present a 43-year-old woman with a major complaint of non-healing sores on the left zygomatic region, close to the medial canthus, with frequent episodes of bleeding and itching since one year before admission. The lesion was excised and followed by histopathological examination, which revealed the BCC diagnosis with tumor-free edges. Closure of the defect with a rotation advancement flap was performed with good results. Discussion: The diagnosis of BCC in this patient was based on history taking, dermatological and histopathological examination. According to the dermatological examination, the patient presented with superficial ulcers with hyperpigmented bases, irregular margins and raised edges, partly covered by crust in the left zygomatic region, consistent with typical clinical manifestation of BCC. Histopathological findings of BCC may vary according to the subtype. However, most cases of BCCs usually have similar histological characteristics. Conclusion: The functional and cosmetic result of BCC following excision and defect closure with rotation advancement flap yielded good results with a shorter healing time.
Tuberkulosis Gumma pada Pasien Tuberkulosis Paru Donytasari, Fitri Meutia; Dalimunthe, Dina Arwina; Siregar, Remenda
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 1 (2024): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i1.16760

Abstract

Background: Tuberculosis (TB) gumma (metastatic tuberculous abscess) is a rare form of cutaneous TB, generally occurring in malnourished and immunocompromised patient. Case: A 24 year old man with a chief complaint of ulcers accompanied by a thick pigmented crusts on the neck and left abdomen without pain since 3 months ago. Initially, 6 months ago a small skin coloured lump the size of a green bean seed arised on the stomach and neck, not itchy or painful. One month later, the mass got bigger, ulcerated, and pus drainage were seen. The patient was also currently diagnosed with pulmonary TB. Dermatological examination showed an ulcer with a diameter of 10 cm with crusts and pus with irregular edges and hyperpigmentation in the left colli region and an ulcer with a diameter of 15 cm with crusts and pus with irregular edges and hyperpigmentation in the left lumbar region. The results of histopathological examination of the dermis showed fibrocollagenous connective tissue with infiltration of inflammatory lymphocytes and PMN cells, localized clusters of epithelioid cells with central necrosis and Langhans multinucleated giant cells were found. Discussion: Gumma tuberculosis is a multibacillary variant of cutaneous TB with a focus on hematogenous spread. Antituberculosis drugs are given according to the phase and the dose is according to the patient's body weight. Conclusion: A case of gumma tuberculosis has been reported in an immunocompetent young adult patient with pulmonary tuberculosis. The prognosis in patients is generally good. Pendahuluan: Tuberkulosis (TB) gumma (abses tuberkulosis metastatik) adalah bentuk TB kutis yang jarang, umumnya terjadi pada keadaan malnutrisi dan imunokompromais. Kasus: Seorang laki-laki berusia 24 tahun dengan keluhan utama luka borok disertai dengan keropeng hitam yang tebal pada leher dan perut kiri yang tanpa rasa nyeri sejak 3 bulan lalu. Awalnya, 6 bulan yang lalu pasien merasakan adanya benjolan kecil seukuran biji kacang hijau pada perut dan leher yang sewarna kulit dan tidak terasa gatal maupun nyeri. Satu bulan setelahnya benjolan dirasakan semakin membesar kemudian pecah dan mengeluarkan nanah. Pasien saat ini juga didiagnosis dengan TB paru. Dari pemeriksaan dermatologis tampak ulkus dengan diameter 10 cm disertai krusta dan pus dengan tepi ireguler dan hiperpigmentasi pada regio colli sinistra dan ulkus dengan diameter 15 cm disertai krusta dan pus dengan tepi ireguler dan hiperpigmentasi pada regio lumbalis sinistra. Hasil histopatologis dari jaringan regio abdomen dekstra menunjukan bagian dermis terdiri dari jaringan ikat fibrokolageneus dengan infiltrasi sel-sel radang limfosit dan PMN, setempat tampak kelompokan sel-sel epiteloid dengan nekrosis sentral dan dijumpai Langhans multinucleated giant cell. Diskusi: Tuberkulosis gumma merupakan varian multibasiler dari TB kutis dengan fokus penyebaran secara hematogen. Obat antituberkulosis (OAT) diberiksan sesuai fase dan dosis disesuaikan dengan berat badan pasien. Kesimpulan: Telah dilaporkan satu kasus tuberkulosis gumma pada pasien dewasa muda imunokompeten yang mengalami tuberkulosis paru. Prognosis pada pasien umumnya baik.
PENATALAKSANAAN BEDAH EKSISI KARSINOMA SEL BASAL DAN PENUTUPAN DEFEK DENGAN TEKNIK READING MAN FLAP Siregar, Remenda; Hutagalung, Patricia S. U . Br; Tambunan, Regina Maharani
Media Dermato-Venereologica Indonesiana Vol 52 No 4 (2025): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v52i4.501

Abstract

Pendahuluan: Karsinoma sel basal (KSB) jenis kanker kulit dari sel-sel pluripotensial pada lapisan basal epidermis yang sering disebabkan pajanan sinar matahari. Terapi KSB dapat dilakukan secara bedah dan non-bedah. Pada laporan kasus ini KSB ditatalaksana dengan bedah dilanjutkan penutupan defek dengan teknik reading man flap. Kasus: Seorang laki-laki, 65 tahun, datang dengan keluhan luka yang tidak sembuh, sering berdarah dan gatal pada pelipis kanan sejak 6 bulan lalu. Awalnya 3 tahun yang lalu timbul bintil kecil sewarna kulit, berukuran sebesar mata jarum pentul tanpa disertai rasa gatal. Satu tahun yang lalu bintil tersebut mulai terasa gatal sesekali dan mudah berdarah ketika digaruk. Pada pemeriksaan dermatologis dijumpai plak hiperpigmentasi disertai ulkus superfisial dan krusta, berbatas tegas, tepi ireguler. Dari pemeriksaan dermoskopi dijumpai ulserasi disetai krusta, superficial fine telangiectasis, maple leaf-like area, dan blue-gray ovoid nest. Pasien didiagnosis dengan karsinoma sel basal dan dilakukan eksisi dengan reading man flap. Diskusi: KSB pada pasien ini dijumpai pada regio temporal kanan, sehingga tindakan eksisi dengan teknik reading man flap sesuai menjadi pilihan utama pengangkatan tumor tersebut. Kesimpulan: Pada kasus ini, teknik reading man flap merupakan teknik pilihan untuk penutupan defek karena memiliki beberapa keuntungan yaitu distorsi minimal dengan risiko infeksi yang rendah. Prognosis pasien dengan KSB dengan penanganan sesuai adalah sangat baik.
The profile of skin cancer patients at Dr Pirngadi Hospital Medan: A retrospective study Lingga, Febrina Dewi Pratiwi; Indira, Aisya; Siregar, Remenda
Journal of General - Procedural Dermatology and Venereology Indonesia Vol. 9, No. 2
Publisher : UI Scholars Hub

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Abstract

Background: Skin cancer is among the most common malignancies, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma. In Indonesia, it ranks third after cervical and breast cancer. This study aimed to analyze the demographic, clinical, and treatment patterns of skin cancer cases at Dr. Pirngadi General Hospital, Medan, Indonesia from 2019 to 2023. Methods: A retrospective descriptive study was conducted using medical record data of all skin cancer patients treated from 2019 to 2023. Variables analyzed included age, sex, occupation, lesion site, skin cancer type, and treatment modality. Data were analyzed using univariate statistics and presented as frequency distributions. Results: A total of 106 patients were included, most aged >50 years (73.6%) and male (60.4%). Outdoor occupations, such as farming (23.6%) and entrepreneurship (23.6%), were the most common. Lesions were predominantly located on the face (93.4%). BCC was the most frequent type (90.6%), followed by SCC (7.5%) and melanoma (1.9%). Excisional surgery was the main treatment (51.9%), followed by excision with skin flap reconstruction (48.1%). Conclusion: Skin cancer in this study was most prevalent among older males with outdoor occupations, with the face being the most frequent lesion site. BCC was the predominant type, and excisional surgery remained the primary treatment. These findings provide an updated epidemiological overview to support prevention and early detection efforts in Indonesia.
Co-Authors Dina Arwina Dalimunthe, Dina Arwina Donytasari, Fitri Meutia Fitri Puspita Hutagalung, Patricia S. U . Br Indira, Aisya Juliyanti -, Juliyanti LINGGA, FEBRINA DEWI PRATIWI Nurhayati, Raja Oentari, Widyaningsih Rangkuti, Irwan Fahry Sari, Ari Karmila Tambunan, Regina Maharani