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Evaluasi Dengan High Resolution Computed Tomography (HRCT) Setelah Infeksi Covid-19: Laporan Kasus di Rumah Sakit dr. Kariadi Semarang Satoto, Bambang; Widyasari, Maya Nuriya; Apriansah, Apriansah
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1A (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (468.567 KB) | DOI: 10.36408/mhjcm.v7i1A.469

Abstract

Pendahuluan SARS-CoV-2 merupakan virus RNA yang terutama menginfeksi sel-sel pada saluran napas pelapis alveoli. Virus SARS-CoV-2 yang terhirup mengikat sel epitel di rongga hidung dan mulai bereplikasi. Virus ini menyebar serta bermigrasi ke saluran pernapasan, memicu respons imun bawaan dan pada akhirnya berkembang menjadi Acute Respiratory Distress Syndrome (ARDS). Gambaran ground glass infiltrates dapat terdeteksi pada pencitraan toraks. Pemeriksaan X-ray toraks dan MSCT toraks memegang peranan penting dalam deteksi dan follow up COVID-19. Metode dan Bahan Laporan kasus 2 pasien laki-laki yang terkonfirmasi COVID-19 umur 43 tahun dan 48 tahun dengan keluhan utama sesak napas, batuk dan demam. Pasien pertama mempunyai riwayat perjalanan ke Amerika Serikat 3 minggu sebelum masuk rumah sakit, sedangkan pasien kedua mempunyai riwayat kontak dengan pasien terkonfirmasi COVID-19. Pada pemeriksaan X-ray toraks kedua pasien menunjukkan gambaran konsolidasi disertai air bronchogram pada lapangan paru bilateral yang tampak dominan pada perifer. Berdasarkan pedoman Severe Acute Respiratory Syndrome (SARS) terdahulu, evaluasi dapat dilakukan 2 bulan dan 6 bulan setelah terinfeksi. Dua bulan setelah terinfeksi COVID-19 dilakukan pemeriksaan HRCT toraks dengan hasil normal. Kesimpulan Lesi berupa konsolidasi disertai air bronchogram dengan distribusi yang dominan pada perifer merupakan gambaran radiologis yang khas pada pasien Covid-19 seperti yang ditemukan pada kedua kasus yang dipaparkan dalam artikel ini. Evaluasi sequele dengan pemeriksaan HRCT yang dilakukan 2 bulan pasca penyembuhan menunjukkan gambaran paru paru yang normal, tidak ada infiltrat maupun fibrosis pada kedua pasien tersebut. Kata kunci X-ray toraks, konsolidasi, air bronchogram, COVID-19 Introduction SARS-CoV-2 is an RNA virus that mainly infects cells in the alveoli lining airways. The inhaled virus binds to epithelial cells in the nasal cavity then begins to replicate. This virus spreads, migrates to the respiratory tract, triggering an innate immune response, and develop to Acute Respiratory Syndrome. The ground-glass opacities can be detected in thoracic imaging eventually. Chest X-ray and CT-scan have an important role in the detection and follow-up of COVID-19. Materials and Methods The case report of 2 male patients confirmed COVID-19 aged 43 years and 48 years with major complaints of shortness of breath, coughing, and fever. The first patient had a history of raveling to the United States 3 weeks before hospitalization, while the second patient had a history of contact with a confirmed COVID-19 patient. On chest X-ray examination, both patients showed multiple consolidation with air bronchogram in bilateral lung field which appeared dominant in the periphery. According to the previous Severe Acute Respiratory Syndrome (SARS) guideline, evaluation for patients can be done in two months and six months after firstly infected. Two months after COVID-19 infection, a chest HRCT examination was performed with normal results. Conclusion Consolidation with air bronchogram which dominantly seen in peripheral distribution is a typical radiological picture in COVID-19 patients as found in two cases described in this article. Sequelae evaluation with chest HRCT conducted 2 months after healing showed normal lung appearance with no sign of infiltrates or fibrosis seen in both patients. Keywords: Chest X-ray, consolidation, air bronchogram, COVID-19
Correlation Between Brixia Score Imaging and Clinical Laboratory Results In Severe-Critical Covid-19 Patients Receiving Standard Therapy Compared To Tocilizumab Fitriani, Aulia; Wahyuni, Frederica Mardiana; Satoto, Bambang; Handoyo, Thomas; Santoso, Antonius Gunawan; Nawangsih, Christina Hari; Baskoro, Nurdopo
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.991

Abstract

Background. Coronavirus infection disease 19 (COVID-19) is a global health issue. Brixia score and inflammatory markers can assess COVID-19 severity. Severe-critical phase becomes the main concern of clinicians in the management of COVID-19 to reduce mortality. Standard therapy for moderate to severe COVID-19 is convalescent plasma which functions as an antiviral and immunomodulator, while tocilizumab is an IL-6 antagonist which underlies the occurrence of cytokine storms in severe-critical COVID-19. Aims. To examine the correlation between the Brixia score and clinical laboratory results in patients with severe-critical degree of Covid-19 who received both standard therapy and tocilizumab Method. A retrospective cohort study of Brixia score, with clinical laboratory results of D-dimer, fibrinogen, ferritin, and CRP (C-reactive protein) COVID-19 patients with severe-critical phase who were administered standard therapy and tocilizumab who were treated at RSUP DR Kariadi Semarang, then a correlation was carried out between the Brixia score and clinical laboratory results using a correlation test Spearman. Results. The research data consisted of 72 subjects divided into groups that were adiminstered tocilizumab therapy (36 subjects) and standard therapy (36 subjects). There was a significant correlation between the Brixia score and the D-dimer result with p = 0.024 (p <0.05), correlation coefficient = 0.377 in the standard pre-therapy and post therapy. A p-value of less than 0.05 indicates no significant correlation between the Brixia score and clinical laboratory results before or after tocilizumab therapy. Conclusion. There is a significant correlation between the Brixia score results and the D-dimer results in COVID-19 patients who are adiministered standard therapy, but not significant correlation in tocilizumab
Significant Relationship Between Brixia Score And The Degree Of Acute Respiratory Distress Syndrome In Covid 19 Patients Ibrahim, Irni Dwi Aprianty; Satoto, Bambang; Handoyono, Thomas; Santoso, Antonius Gunawan; Sukmaningtyas, Hermina; NINGRUM, FARAH HENDARA
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 2 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i2.993

Abstract

BACKGROUND: Chest X-ray has an important role in detecting early features of COVID-19. To improve risk stratification, a scoring system in chest x-ray called Brixia Score was developed. The Brixia score is designed to measure the severity of lung abnormalities in COVID-19, with an 18-point severity scale. Deaths in COVID-19 occur mainly due to Acute Respiratory Distress Syndrome (ARDS). ARDS is classified into mild, moderate, and severe degrees. If the degree can be predicted earlier, patients can receive earlier therapy and death rate can be reduced. AIMS:  to analyze relationship between Brixia Score and degree of ARDS in COVID-19 patients. METHOD: the research used an observational analytic method with a cross-sectional approach to 95 subjects who are positive for COVID-19 and diagnosed with ARDS, in January to December 2021. Brixia Score data was collected based on chest X-ray expertise, ARDS degree was based on medical records and blood gas analysis. Analysis of relationship between Brixia score and degree of ARDS was carried out using the Kruskal-Wallis test. RESULT:  There was a significant difference in Brixia score based on degree of ARDS (p value <0.05). The highest Brixia score was obtained in severe ARDS, while the low Brixia score was obtained in mild ARDS. This proves that there is a relationship between Brixia score and degree of ARDS. CONCLUSION: Brixia score has a significant relationship to the degree of ARDS in COVID-19 patients.
The Relationship between the Duration of Suffering from Diabetes and HbA1c Levels with the Degree of Liver Stiffness in Type 2 Diabetes Mellitus Patients Amna, Faza Khilwan; Widyasari, Maya Nuriya; Purnomo, Hery Djagat; Wahyuni, Frederica Mardiana; Satoto, Bambang; Sukmaningtyas, Hermina
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1011

Abstract

BACKGROUND : Type 2 diabetes mellitus (DM) is one of the major problems faced by the health system. Diabetes is a multifactorial, chronic and progressive metabolic disorder characterized by chronic hyperglycemia. Persistent hyperglycemia is associated with long-term damage to the  liver. Ultrasound elastography is one of imaging modality that can assess liver stiffness, thus can assist clinicians in determining therapy, evaluating, and predicting disease progression. AIMS :  Aim of this study was to determine the relationship between liver stiffness degree by using ultrasound elastography with the duration of T2DM and HbA1c levels. METHOD : This study was an observational analytic research with a cross-sectional approach which carried out from May to September 2022 at the radiology department of Dr. Kariadi Hospital Semarang. Fifty subjects were included in this study and Rank-Spearman correlation test was used to analyze the relationship between liver stiffness degree with T2DM duration and HbA1c levels. RESULT :  Using ultrasonography elastography, the liver stiffness average was 7.92 + 6.72 kPa. The average of HbA1c levels was 8.55 + 2.63%. T2DM duration average was 9.10 + 6.50 years.   The rank-spearman test showed a significant correlation between HbA1c levels and the degree of liver stiffness (p = 0.000) with a correlation coefficient (r) of 0.68. There was no significant correlation between the T2DM duration and the degree of liver stiffness (p = 0.052). CONCLUSION : There was a significant correlation between liver stiffness and HbA1c levels, but there is no correlation between liver stiffness and T2DM duration
Kualitas Sistem Informasi Pelaporan Standar Pelayanan Minimal Instalasi Radiologi Berbasis Web (e-spmrad.com) Romadhoni, Efriza Nur; Santoso, Bedjo; Darmini, Darmini; Satoto, Bambang; Wibowo, Gatot Murti
Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Vol 8, No 2 (2022): JMK Yayasan RS.Dr.Soetomo, Kedua 2022
Publisher : STIKES Yayasan RS.Dr.Soetomo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (164.701 KB) | DOI: 10.29241/jmk.v8i2.972

Abstract

ABSTRAKPengembangan laporan Standar Pelayanan Minimal (SPM) radiologi diharapkan dapat mempermudah dan mendukung proses pengambilan keputusan. e-spmrad.com sebagai sistem pelaporan SPM radiologi yang dikembangkan pada tahun 2021 ekuivalen sebagai pelaporan SPM radiologi, Namun dalam penelitian belum dilakukan analisis terhadap kualitas sistem, kualitas informasi dan kepuasan pengguna. Padahal, kualitas sistem dan kualitas informasi mempengaruhi kepuasan pengguna sistem terhadap penggunaan sistem informasi. Penelitian ini bertujuan untuk menganalisis e-spmrad.com efektif terhadap kualitas sistem informasi dalam pelaporan standar pelayanan minimal instalasi radiologi. Desain penelitian ini adalah kuantitatif. Penelitian dilaksanakan di instalasi radiologi RSUI Madinah Kasembon Malang pada Bulan Februari- Juli 2021. Uji coba dalam penelitian ini menggunakan rancangan penelitian pre-eksperimen design dengan rancangan one group pre-post test. Berdasarkan hasil penelitian terdapat perbedaan kualitas sistem, kualitas informasi dan kepuasan pengguna pada seluruh aspek sebelum dengan sesudah pemberian sistem baru (p-value ≤ 0,005). sehingga dapat disimpulkan bahwa sistem informasi pelaporan standar pelayanan minimal instalasi radiologi efektif terhadap kualitas sistem informasi dalam pelaporan standar pelayanan minimal instalasi radiologi, terbukti nilai p-value adalah 0,005.
OPTIMALISASI PENGADAAN MRI MELALUI TARGET KUNJUNGAN PASIEN DI ERA JAMINAN KESEHATAN NASIONAL Santosa, Gatot; Satoto, Bambang; Indrati, Rini; Susanto, Edy; Budiati, Tri Asih; Hariri, Ahmad
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.34623

Abstract

Sektor kesehatan merupakan aspek fundamental dari kehidupan manusia, membutuhkan perhatian berkelanjutan dari pemerintah untuk meningkatkan kualitas layanan. Dalam layanan radiologi, khususnya Magnetic Resonance Imaging (MRI), upaya mengoptimalkan penggunaan sumber daya sangat penting karena biaya peralatan yang tinggi dan kompleksitas operasi. Studi ini mengembangkan formula komputasi yang dirancang untuk membantu kepala departemen radiologi dalam merencanakan dan menghitung target pemeriksaan MRI harian selama masa pakai peralatan. Faktor-faktor seperti jenis rumah sakit, biaya layanan, biaya operasional, dan lokasi regional dimasukkan ke dalam rumus. Penelitian ini menggunakan pendekatan metode campuran, menggabungkan survei pendahuluan dengan pengembangan dan validasi rumus komputasi. Validasi oleh pakar keuangan dan radiologi menunjukkan keandalan dan akurasi formula. Selain itu, pengujian skala besar yang melibatkan sepuluh pemangku kepentingan mengkonfirmasi fungsionalitas, keandalan, dan keramahan pengguna aplikasi. Hasil menunjukkan bahwa alat ini secara signifikan meningkatkan perencanaan dan manajemen operasional peralatan MRI, menawarkan solusi yang dapat disesuaikan dengan peraturan baru dan data waktu nyata. Aplikasi ini memberikan metode yang menjanjikan untuk mengoptimalkan penggunaan MRI di rumah sakit, terutama dalam konteks sistem Jaminan Kesehatan Nasional (JKN). Fleksibilitas dan kemudahan penggunaannya membuatnya berlaku untuk rumah sakit pemerintah dan swasta, memastikan pemanfaatan MRI dan manajemen keuangan yang efektif.
Application of Fusion Technique with ImageJ Stacks Feature for Brain Tumor MRI Image Optimization Tajuddin, Nur Wahyu; Satoto, Bambang; Indrati, Rini; Kristanto Mulyantoro, Donny; Darmini, Darmini; Murti Wibowo, Gatot
Asian Journal of Social and Humanities Vol. 2 No. 11 (2024): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v2i11.359

Abstract

Fusion techniques on MRI for brain tumors can provide comprehensive visualization by combining Axial T2-Flair and Axial T1-GD (T1-weighted post-contrast) sequence images. Fusion MRI in brain tumors is able to clearly display the location, size and characteristics of the tumor. However, not all institutions can install such additional fusion software due to significant additional costs. Therefore, this study aims to prove that the Stacks feature on ImageJ as an alternative can be optimal in visualizing brain tumor image information through MRI fusion techniques. This study used 17 image samples with a quasi experimental design post test only without control group design to compare three analysis methods, namely fusion maximum intensity, minimum intensity and average intensity so that the most suitable projection can be determined. The evaluation of image quality was carried out through a histogram which was then analyzed with a crucal-wallis and the Mann Whitney u test, while the analysis of pathological information used a crucal-wallis, followed by a post hoc test and continued with Mann Whitney u for further analysis. The results show that the stacks feature on ImageJ can be used in the application of fusion techniques so that it will improve the contrast and sharpness of MRI images, especially in areas with high tumor activity. MRI images of brain tumors with maximum fusion intensity produced images with the highest average gray level and the best pathological information. This projection is more optimal than the minimum intensity and average intensity because it provides a more detailed and clear visualization of brain tumors.
An Oral Sedation Preparation Based on Pistachio Nuts with Organic Melatonin Content To Support MRI Examination Surya Wrddhi Putra, IM Dwitya; Satoto, Bambang; Dartini, Dartini; Masrochah, Siti; Latifah, Leny; Murti Wibowo, Gatot
Asian Journal of Social and Humanities Vol. 3 No. 3 (2024): Asian Journal of Social and Humanities
Publisher : Pelopor Publikasi Akademika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59888/ajosh.v3i3.466

Abstract

Sedation of propofol, chloral hydrate, midazolam, and ketamine is commonly used in MRI examinations. There are still risky side effects from the previous 4 sedations, so melatonin tablets are a safer option. Melatonin synthesized in tablets can still cause quite adverse side effects. Pistachios processed into milk can be used as an alternative to natural melatonin oral sedation. Research Objective: To determine the potential of pistachio milk as an alternative to oral melatonin sedation to support MRI examinations. Research Method: This research uses the R&D (Research and Development) method with 4 stages, namely finding potentials and problems, data collection, product design, and design validation. The product in the form of 200 mL pistachio milk with concentration variants of 35 g, 45 g, 55 g, 65 g was tested in a laboratory to determine its potential from the test results with a reference to melatonin tablets of 10 mg. Research Results: Laboratory tests showed the presence of melatonin and other accompanying ingredients such as phenolics, carotene, and polyphenols. The melatonin content of the 35 g, 45 g, 55 g, 65 g variants is 5.5 mg, 6.1 mg, 8.7 mg, 10.5 mg, respectively. Conclusion: Pistachio milk with a 65 g variant has a melatonin content of 10.5 mg which is close to the reference for sedation of melatonin tablets of 10 mg, so it has the potential to be an alternative to oral sedation of melatonin to support MRI examinations.
Optimizing MRI Examination Planning through a Computational Formula: A Mixed-Method Study of Radiology Management in Indonesian Hospitals Santosa, Gatot; Satoto, Bambang; Indrati, Rini; Susanto, Edy; Asih Budiati, Tri; Hariri, Ahmad
Journal of Multidisciplinary Sustainability Asean Vol. 1 No. 5 (2024)
Publisher : Yayasan Adra Karima Hubbi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70177/ijmsa.v1i5.1335

Abstract

Background. The healthcare sector is a fundamental aspect of human life, requiring continuous attention from governments to improve service quality. In radiology services, particularly Magnetic Resonance Imaging (MRI), optimizing resource use is crucial due to high equipment costs and the complexity of operations. Purpose. This study develops a computational formula designed to assist radiology department heads in planning and calculating daily MRI examination targets during the equipment's lifespan. Factors such as hospital type, service fees, operational costs, and regional location are incorporated into the formula. Method. The research employs a mixed-method approach, combining preliminary surveys with the development and validation of the computational formula. Validation by financial and radiology experts demonstrated the formula's reliability and accuracy. Additionally, large-scale testing involving ten stakeholders confirmed the application's functionality, reliability, and user-friendliness. Results. The Results show that this tool significantly improves the planning and operational management of MRI equipment, offering a solution that is adaptable to new regulations and real-time data. Conclusion. This application provides a promising method for optimizing MRI use in hospitals, particularly within the context of the National Health Insurance (JKN) system. Its flexibility and ease of use make it applicable for both government and private hospitals, ensuring effective MRI utilization and financial management.
Peningkatan Akurasi Diagnostik Tissue Harmonic Imaging Ultrasound pada Populasi Overweight: Evaluasi Komparatif Ketajaman Dinding, Artefak Intralumen, dan Ketajaman Lesi Pratiwi, Rahayu Nia; Rianto, Sugeng; Setiawan, Agung Nugroho; Rasyid, Rasyid; Satoto, Bambang; Hariri, Ahmad
Jurnal Ners Vol. 10 No. 1 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.52205

Abstract

Latar belakang: Kualitas citra pada ultrasonografi abdomen menurun secara signifikan pada pasien dengan indeks massa tubuh (BMI) tinggi akibat redaman akustik oleh jaringan adiposa. Keterbatasan ini mempengaruhi akurasi diagnostik penyakit kandung empedu, termasuk kolelitiasis, kolesistitis, dan polip. Tissue Harmonic Imaging (THI) dikembangkan untuk mengatasi degradasi citra dengan memanfaatkan propagasi gelombang non-linier yang menghasilkan frekuensi harmonik berkoherensi tinggi. Tujuan: Mengevaluasi secara kuantitatif dampak THI terhadap tiga parameter utama kualitas citra ultrasonografi kandung empedu ketajaman dinding anterior, penekanan artefak intra-lumen, dan kejelasan margin lesi pada pasien kelebihan berat badan. Metode: Studi komparatif berpasangan dilakukan pada 100 pasien BMI >25 kg/m² di Tirta Medical Center (Mei–Juni 2023). Setiap peserta menjalani dua urutan pencitraan berurutan: non-THI (fundamental imaging) dan THI, dengan parameter teknis yang distandarisasi. Dua radiolog independen menilai total 200 citra menggunakan skala ordinal empat tingkat (1–4). Hasil: THI menunjukkan peningkatan signifikan pada seluruh parameter dibandingkan non-THI. Ketajaman dinding anterior mencapai skor 2–3 pada 86% citra THI, sementara non-THI didominasi skor 1–2 (94%). Penekanan artefak internal meningkat drastis, dengan THI mencapai skor tertinggi (4) pada 52% citra dibanding 21% pada non-THI. Kejelasan lesi juga lebih baik pada THI (80% skor 3) dibanding non-THI (44% skor 3). Kesimpulan: THI secara konsisten meningkatkan kualitas citra ultrasonografi kandung empedu pada pasien kelebihan berat badan melalui peningkatan resolusi spasial, kontras, dan penekanan artefak. Temuan ini mendukung penggunaan THI sebagai protokol pencitraan standar untuk evaluasi hepatobilier pada populasi dengan BMI tinggi.