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All Journal JURNAL PROMOSI KESEHATAN INDONESIA Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Diponegoro International Medical Journal (DIMJ)
Riski Prihatningtias, Riski
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology Neuroscience Public Health

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HUBUNGAN LAMA PEMAKAIAN LENSA KONTAK DENGAN MATA KERING Syaqdiyah, Widya Halimatus; Prihatningtias, Riski; Saubiq, Arnila Novitasari
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.853 KB) | DOI: 10.14710/dmj.v7i2.20675

Abstract

Latar Belakang: Lensa kontak banyak digunakan oleh masyarakat dan penggunaan lensa kontak dapat menyebabkan mata kering, hal itu disebabkan oleh iritasi mekanik terhadap kelenjar meibomian. Kelenjar meibomian menghasilkan lapisan lemak yang berfungsi menghambat penguapan lapisan air mata. Gangguan fungsi kelenjar meibomian menyebabkan lapisan air mata cepat menguap. Lensa kontak juga menurunkan sensitivitas permukaan mata sehingga refleks produksi lapisan air mata menurun. Peningkatan penguapan disertai penurunan produksi lapisan air mata menyebabkan sebagian besar pengguna lensa kontak mengalami mata kering.Tujuan: Mengetahui hubungan lama pemakaian lensa kontak dengan mata kering.Metode: Penelitian ini menggunakan rancangan penelitian observasional dengan pendekatan cross sectional. Subjek penelitian ini adalah 50 mata dari 26 mahasiswi Universitas Diponegoro yang memenuhi kriteria inklusi. Pengumpulan data menggunakan kuesioner. Pemeriksaan mata kering menggunakan tes Schirmer. Analisis data yang digunakan adalah uji korelasi Spearman.Hasil: Berdasarkan dari 50 mata yang telah dilakukan pengukuran tes Schirmer, terdapat 12 mata yang mengalami mata kering dan 38 mata dengan produksi air mata normal. Lama pemakaian lensa kontak dan mata kering memiliki hubungan bermakna (p = 0,007) dengan kekuatan korelasi sedang (r = -0,379).Kesimpulan: Terdapat hubungan bermakna antara lama pemakaian lensa kontak dengan mata kering, yaitu semakin lama memakai lensa kontak kejadian mata kering semakin meningkat.
Correlation between Axial Length and The Occurrence of Refractive Errors Ryan, Kevin Arfa; Maharani, Maharani; Saubig, Arnila Novitasari; Prihatningtias, Riski
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.41855

Abstract

Background: Refractive errors result in difficulty in focusing on an object clearly, leading to blurred vision. A recent study by the WHO has reported that refractive errors have become the leading cause of visual impairment. The development of refractive errors has been a significant concern over the last two decades due to its high prevalence worldwide. One possible condition that may occur in individuals with refractive errors is a change in axial length. Axial length is defined as a measurement from the corneal surface to the retinal surface. Aims: To analyze the correlation between axial length and the occurrence of refractive errors in myopia and hypermetropia patients at the Ophthalmology Department of Diponegoro National Hospital. Methods: This observational analytical study with a cross-sectional design was conducted on 36 eyes from 18 patients; each suffering from myopia and hypermetropia at the Ophthalmology Department of Diponegoro National Hospital. Patients provided informed consent, and then the axial length was measured using ultrasound biometry. Data analysis was performed using univariate analysis and Spearman correlation bivariate analysis. Results: The results of the Spearman statistical test showed a significant correlation between the axial length and the occurrence of myopia (p=0.003) with a moderate correlation strength and the occurrence of hypermetropia (p=0.000001) with a strong correlation strength. Conclusion: The axial length has a significant correlation with the occurrence of refractive errors, especially in myopia and hypermetropia patients. 
The Characteristics of Eye Diseases at Merpati Eye Clinic Dr Kariadi Hospital Semarang in 2020-2022 Rahmi, Fifin Luthfia; Wildan, Arief; Maharani, Maharani; Prihatningtias, Riski; Nugroho, Trilaksana; Rikiandraswida, Zahira; Ryamizard, Rizal
Diponegoro International Medical Journal Vol 4, No 1 (2023): July 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i1.17677

Abstract

Background: The COVID -19 pandemic that has occurred since 2020 has changed and affected all aspects of life. In health services, the pandemic has limited patients from coming to health facilities. Recording of ophthalmology cases in health facilities has an important role in providing information about eye health problems that often occur in the community to identify what are the main challenges faced in the field of eye care.Objective: This study aims to identify the characteristics of eye diseases at the Merpati Eye Polyclinic Dr Kariadi Hospital Semarang in 2020-2022.Methods: This study was a retrospective descriptive study. The clinical characteristic data (gender, age, diagnosis, and Clinic) are retrieved from the medical records of patients suffering from eye diseases who underwent treatment at the Merpati Eye Clinic, Dr. Kariadi Hospital Semarang and was diagnosed in 2020-2022. The data obtained were processed and analyzed using the google sheets program.Results: There were 2961 newly diagnosed patients with the 10 most diagnosed diseases are Refractive disorders (12,87%), Cataracts (11,21%), Glaucoma (10,40%), Diabetic Retinopathy (6,75%), Pseudophakia (5,30%), Papile Atrophy (5,10%), Retinal Vein Occlusion (4,22%), Corneal Ulcer (3,92%), Retinal Detachment (3,71%) and Uveitis (3,51%). Based on age category, the most patients were 51-60 years old (22,29%). Based on gender category, female gender (50,35%) is more than male (49,65%).Conclusion: Of all patients, the 10 most diagnosed diseases were Refractive Disorders, Cataracts, Glaucoma, Diabetic Retinopathy, Pseudophakia, Papillary Atrophy, Retinal Vein Occlusion, Corneal Ulcers, Retinal detachment and Uveitis.
Effect of Moringa Oleifera on Tumor Necrosis Factor-Alpha and Extracellular Matrix Trabecular Meshwork of Glaucoma Model Wistar Rats Maharani, Maharani; Astuti, Ratih Kusuma; Rahmi, Fifin Luthfia; Prihatningtias, Riski; Istiadi, Hermawan; Wildan, Arief
Journal of Biomedicine and Translational Research Vol 11, No 1 (2025): April 2025
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v11i1.24127

Abstract

Background: Elevated intraocular pressure (IOP) induces inflammation in the trabecular meshwork (TM) through increases in tumor necrosis factor-alpha (TNF-α) expressions by activating nuclear factor kappa B (NF-κB). Mechanical injury to the TM, such as increased IOP, can cause extracellular matrix (ECM) remodeling, impacting the permanent outflow of aqueous humor. Moringa oleifera (MO) leaf extract is an anti- inflammatory agent that inhibits NF-κB activation and has been studied to have antioxidant effects.Objective: to analyze the effects of MO leaf extract on TNF- α expression and the thickness of the trabecular meshwork ECM in a Wistar rat glaucoma model. Methods: Fourteen male Wistar rats were divided into two groups (n=7): the glaucoma group received oral MO leaf extract at 300 mg/kg body weight for four weeks, and the control group. TNF-α expressions were measured by immunohistochemical stain, and the thickness of the ECM was examined with hematoxylin eosin staining. P-values of less than 0.05 were considered to represent statistical significance.Results: The mean of TNF-α expressions in the treatment group was 4.29 ± 0.76, and the control group was 5.29 ± 0.49. There was a significant difference in TNF-α expressions between the two groups (p=0.015). The mean thickness of the ECM TM experimental group and control group were 155.65 ± 28.72μm and 218.63 ± 40.85μm respectively. The extracellular matrix TM experimental group was statistically significantly thinner than the control group (p=0.006).Conclusion: MO could protect TM from damage caused by high IOP by suppressed TNF- α expression and ECM thickness in the TM Wistar glaucoma model. 
Sleep Quality and Screen Time as The Most Influential Factor of Computer Vision Syndrome Dhafira, Farhana; Prihatningtias, Riski; Nugroho, Trilaksana; Maharani, Maharani
Jurnal Promosi Kesehatan Indonesia Volume 18 No.2 Agustus 2023
Publisher : Master Program of Health Promotion Faculty of Public Health Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpki.18.2.73-78

Abstract

Background: Since the Covid-19 Pandemic hit Indonesia, college students have had many eye health complaints; one is Computer Vision Syndrome (CVS). Factors that can increase the risk of CVS are decreased sleep quality, high computer/laptop use duration, and a non-ergonomic position. This study aimed to prove the relationship between sleep quality, visibility, and screen time on the incidence of CVS in medical students of Diponegoro University.Method: This cross-sectional study, including 147 medical students was conducted using primary data from questionnaires of Wendy Strouse Watt, Thomas H Murphy, Hospitality Eye Care Center, and vsp.com to gain data on respondent identity, visibility, and screen time. Sleep quality data were taken from the PSQI and CVS data through the CVS-Q questionnaire. Chi-square, Mann-Whittney, and logistic regression of multivariate analysis were used to analyze the data.Results: From 147 subjects, 108 were CVS (73.5%), and 39 were Non-CVS (26.5%). Variables of sleep quality and screen time (total) showed a significant relationship with CVS, which had p-values of p=0.001 and p=0.009 (p<0.05). As for the visibility to CVS, there was no relationship with p=0.863. In the multivariate test, sleep quality (p=0.000; ExpB=4.342) and total screen time (p=0.006; ExpB=3.913) were the most influential variables. The results showed that Computer Vision Syndrome is ubiquitous among Diponegoro University's final-year medical students. Sleep quality and total screen time can increase the risk of CVS by four times. This study also shows that CVS still appears in the post-pandemic era.
Co-Authors Arief Wildan, Arief Astuti, Ratih Kusuma Dhafira, Farhana Fifin Luthfia Rahmi Hermawan Istiadi Maharani Maharani, Maharani Nugroho, Trilaksana Rikiandraswida, Zahira Ryamizard, Rizal Ryan, Kevin Arfa Saubig, Arnila Novitasari Saubiq, Arnila Novitasari Syaqdiyah, Widya Halimatus