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All Journal JURNAL PROMOSI KESEHATAN INDONESIA Jurnal Kedokteran Diponegoro Journal of Biomedicine and Translational Research Diponegoro International Medical Journal (DIMJ) Ophthalmologica Indonesiana
Riski Prihatningtias, Riski
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience Public Health

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HUBUNGAN LAMA PEMAKAIAN LENSA KONTAK DENGAN MATA KERING Syaqdiyah, Widya Halimatus; Prihatningtias, Riski; Saubiq, Arnila Novitasari
DIPONEGORO MEDICAL JOURNAL (JURNAL KEDOKTERAN DIPONEGORO) Vol 7, No 2 (2018): JURNAL KEDOKTERAN DIPONEGORO
Publisher : Faculty of Medicine, Diponegoro University, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.853 KB) | DOI: 10.14710/dmj.v7i2.20675

Abstract

Latar Belakang: Lensa kontak banyak digunakan oleh masyarakat dan penggunaan lensa kontak dapat menyebabkan mata kering, hal itu disebabkan oleh iritasi mekanik terhadap kelenjar meibomian. Kelenjar meibomian menghasilkan lapisan lemak yang berfungsi menghambat penguapan lapisan air mata. Gangguan fungsi kelenjar meibomian menyebabkan lapisan air mata cepat menguap. Lensa kontak juga menurunkan sensitivitas permukaan mata sehingga refleks produksi lapisan air mata menurun. Peningkatan penguapan disertai penurunan produksi lapisan air mata menyebabkan sebagian besar pengguna lensa kontak mengalami mata kering.Tujuan: Mengetahui hubungan lama pemakaian lensa kontak dengan mata kering.Metode: Penelitian ini menggunakan rancangan penelitian observasional dengan pendekatan cross sectional. Subjek penelitian ini adalah 50 mata dari 26 mahasiswi Universitas Diponegoro yang memenuhi kriteria inklusi. Pengumpulan data menggunakan kuesioner. Pemeriksaan mata kering menggunakan tes Schirmer. Analisis data yang digunakan adalah uji korelasi Spearman.Hasil: Berdasarkan dari 50 mata yang telah dilakukan pengukuran tes Schirmer, terdapat 12 mata yang mengalami mata kering dan 38 mata dengan produksi air mata normal. Lama pemakaian lensa kontak dan mata kering memiliki hubungan bermakna (p = 0,007) dengan kekuatan korelasi sedang (r = -0,379).Kesimpulan: Terdapat hubungan bermakna antara lama pemakaian lensa kontak dengan mata kering, yaitu semakin lama memakai lensa kontak kejadian mata kering semakin meningkat.
Correlation between Axial Length and The Occurrence of Refractive Errors Ryan, Kevin Arfa; Maharani, Maharani; Saubig, Arnila Novitasari; Prihatningtias, Riski
Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal) Vol 13, No 2 (2024): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v13i2.41855

Abstract

Background: Refractive errors result in difficulty in focusing on an object clearly, leading to blurred vision. A recent study by the WHO has reported that refractive errors have become the leading cause of visual impairment. The development of refractive errors has been a significant concern over the last two decades due to its high prevalence worldwide. One possible condition that may occur in individuals with refractive errors is a change in axial length. Axial length is defined as a measurement from the corneal surface to the retinal surface. Aims: To analyze the correlation between axial length and the occurrence of refractive errors in myopia and hypermetropia patients at the Ophthalmology Department of Diponegoro National Hospital. Methods: This observational analytical study with a cross-sectional design was conducted on 36 eyes from 18 patients; each suffering from myopia and hypermetropia at the Ophthalmology Department of Diponegoro National Hospital. Patients provided informed consent, and then the axial length was measured using ultrasound biometry. Data analysis was performed using univariate analysis and Spearman correlation bivariate analysis. Results: The results of the Spearman statistical test showed a significant correlation between the axial length and the occurrence of myopia (p=0.003) with a moderate correlation strength and the occurrence of hypermetropia (p=0.000001) with a strong correlation strength. Conclusion: The axial length has a significant correlation with the occurrence of refractive errors, especially in myopia and hypermetropia patients. 
The Characteristics of Eye Diseases at Merpati Eye Clinic Dr Kariadi Hospital Semarang in 2020-2022 Rahmi, Fifin Luthfia; Wildan, Arief; Maharani, Maharani; Prihatningtias, Riski; Nugroho, Trilaksana; Rikiandraswida, Zahira; Ryamizard, Rizal
Diponegoro International Medical Journal Vol 4, No 1 (2023): July 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i1.17677

Abstract

Background: The COVID -19 pandemic that has occurred since 2020 has changed and affected all aspects of life. In health services, the pandemic has limited patients from coming to health facilities. Recording of ophthalmology cases in health facilities has an important role in providing information about eye health problems that often occur in the community to identify what are the main challenges faced in the field of eye care.Objective: This study aims to identify the characteristics of eye diseases at the Merpati Eye Polyclinic Dr Kariadi Hospital Semarang in 2020-2022.Methods: This study was a retrospective descriptive study. The clinical characteristic data (gender, age, diagnosis, and Clinic) are retrieved from the medical records of patients suffering from eye diseases who underwent treatment at the Merpati Eye Clinic, Dr. Kariadi Hospital Semarang and was diagnosed in 2020-2022. The data obtained were processed and analyzed using the google sheets program.Results: There were 2961 newly diagnosed patients with the 10 most diagnosed diseases are Refractive disorders (12,87%), Cataracts (11,21%), Glaucoma (10,40%), Diabetic Retinopathy (6,75%), Pseudophakia (5,30%), Papile Atrophy (5,10%), Retinal Vein Occlusion (4,22%), Corneal Ulcer (3,92%), Retinal Detachment (3,71%) and Uveitis (3,51%). Based on age category, the most patients were 51-60 years old (22,29%). Based on gender category, female gender (50,35%) is more than male (49,65%).Conclusion: Of all patients, the 10 most diagnosed diseases were Refractive Disorders, Cataracts, Glaucoma, Diabetic Retinopathy, Pseudophakia, Papillary Atrophy, Retinal Vein Occlusion, Corneal Ulcers, Retinal detachment and Uveitis.
Effect of Moringa Oleifera on Tumor Necrosis Factor-Alpha and Extracellular Matrix Trabecular Meshwork of Glaucoma Model Wistar Rats Maharani, Maharani; Astuti, Ratih Kusuma; Rahmi, Fifin Luthfia; Prihatningtias, Riski; Istiadi, Hermawan; Wildan, Arief
Journal of Biomedicine and Translational Research Vol 11, No 1 (2025): April 2025
Publisher : Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jbtr.v11i1.24127

Abstract

Background: Elevated intraocular pressure (IOP) induces inflammation in the trabecular meshwork (TM) through increases in tumor necrosis factor-alpha (TNF-α) expressions by activating nuclear factor kappa B (NF-κB). Mechanical injury to the TM, such as increased IOP, can cause extracellular matrix (ECM) remodeling, impacting the permanent outflow of aqueous humor. Moringa oleifera (MO) leaf extract is an anti- inflammatory agent that inhibits NF-κB activation and has been studied to have antioxidant effects.Objective: to analyze the effects of MO leaf extract on TNF- α expression and the thickness of the trabecular meshwork ECM in a Wistar rat glaucoma model. Methods: Fourteen male Wistar rats were divided into two groups (n=7): the glaucoma group received oral MO leaf extract at 300 mg/kg body weight for four weeks, and the control group. TNF-α expressions were measured by immunohistochemical stain, and the thickness of the ECM was examined with hematoxylin eosin staining. P-values of less than 0.05 were considered to represent statistical significance.Results: The mean of TNF-α expressions in the treatment group was 4.29 ± 0.76, and the control group was 5.29 ± 0.49. There was a significant difference in TNF-α expressions between the two groups (p=0.015). The mean thickness of the ECM TM experimental group and control group were 155.65 ± 28.72μm and 218.63 ± 40.85μm respectively. The extracellular matrix TM experimental group was statistically significantly thinner than the control group (p=0.006).Conclusion: MO could protect TM from damage caused by high IOP by suppressed TNF- α expression and ECM thickness in the TM Wistar glaucoma model. 
Sleep Quality and Screen Time as The Most Influential Factor of Computer Vision Syndrome Dhafira, Farhana; Prihatningtias, Riski; Nugroho, Trilaksana; Maharani, Maharani
Jurnal Promosi Kesehatan Indonesia Volume 18 No.2 Agustus 2023
Publisher : Master Program of Health Promotion Faculty of Public Health Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpki.18.2.73-78

Abstract

Background: Since the Covid-19 Pandemic hit Indonesia, college students have had many eye health complaints; one is Computer Vision Syndrome (CVS). Factors that can increase the risk of CVS are decreased sleep quality, high computer/laptop use duration, and a non-ergonomic position. This study aimed to prove the relationship between sleep quality, visibility, and screen time on the incidence of CVS in medical students of Diponegoro University.Method: This cross-sectional study, including 147 medical students was conducted using primary data from questionnaires of Wendy Strouse Watt, Thomas H Murphy, Hospitality Eye Care Center, and vsp.com to gain data on respondent identity, visibility, and screen time. Sleep quality data were taken from the PSQI and CVS data through the CVS-Q questionnaire. Chi-square, Mann-Whittney, and logistic regression of multivariate analysis were used to analyze the data.Results: From 147 subjects, 108 were CVS (73.5%), and 39 were Non-CVS (26.5%). Variables of sleep quality and screen time (total) showed a significant relationship with CVS, which had p-values of p=0.001 and p=0.009 (p<0.05). As for the visibility to CVS, there was no relationship with p=0.863. In the multivariate test, sleep quality (p=0.000; ExpB=4.342) and total screen time (p=0.006; ExpB=3.913) were the most influential variables. The results showed that Computer Vision Syndrome is ubiquitous among Diponegoro University's final-year medical students. Sleep quality and total screen time can increase the risk of CVS by four times. This study also shows that CVS still appears in the post-pandemic era.
Color Field Test Charts Vs HVFA In Detection Visual Field Defect Chronic Primary Glaucoma Tanoko, Ivana; Winarto, Winarto; Nugroho, Trilaksana; Prihatningtias, Riski; Rahmi, Fifin L
Majalah Oftalmologi Indonesia Vol 48 No 2 (2022): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v48i2.100663

Abstract

Introduction: Glaucoma is syndrome consist of glaucomatous optic neuropathy, destruction of retinal nerve fiber layer, and typical visual field defects. Color field test charts (CFTC) is a simple and generous instrument used to detect central and paracentral scotoma in neuro-ophthalmology patient. Diagnostic study will perform in this research to compare visual field defects, detecting in chronic primary glaucoma patient between CFTC and HVFA SITA 10-2 as gold standard. Methods: Seventy two eyes from 50 patients with chronic primary glaucoma were examined visual acuity, funduscopy, color blindness, HVFA SITA 10-2 and CFTC. The results CFTC and HVFA were read by 2 ophthalmologists, and kappa agreement was done. Analysis was done to get sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), accuracy, positive and negative likelihood ratio (LR). Result: The sensitivity of CFTC was 87.93%, specificity 85.71%, PPV 96.22%, NPV 63.16%, accuracy 87.5%, positive LR 6.15 and negative LR 0.14 in detecting visual field defect chronic primary glaucoma patient compared to HVFA SITA 10-2. Area Under Curve (AUC) in this research was 0.86 (95% CI 0.751-0.985, p<0.001). Sensitivity, PPV, and accuracy was higher in MD >-12dB compared to <-12dB. There was strong correlation between it in location of defect (Cramer’s correlation; V=0.679, p<0.001), although the large of visual field defect was significantly different between 2 instruments (p<0.05). Conclusion: Color field test charts is comparable to HVFA SITA 10-2 in detecting visual field defect chronic primary glaucoma moderate and advance stage.
OPTICAL COHERENCE TOMOGRAPHY PREDICTS VISUAL RECOVERY OF PATIENTS WITH PITUITARY ADENOMA FOLLOWING SURGERY IN DR KARIADI HOSPITAL,SEMARANG Nitihapsari, Galuh Yulieta; Prihatningtias, Riski
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/tfztq864

Abstract

Introduction and Objective: The characteristics, symptoms, and clinical manifestations of pituitary adenoma in Indonesia have not been widely studied. In 26 patients undergoing pituitary surgery at Dr. Kariadi Hospital, we compared visual acuity pre-operative and post-operative from normal and thin optical coherence tomography (OCT) of the retinal nerve fiber layer (RNFL) and ganglion cell layer-internal plexiform layer (GCL-IPL). Method: A retrospective study of the medical record from January 2020 to December 2022 was done. 21 of the 26 patients had surgery by the transsphenoidal route and the rest by craniotomy. All patients had macroadenoma (tumor size >1cm) and were histologically confirmed. Visual acuity before and after surgery was evaluated along with the patient’s OCT value. Result: The thinner pre-operative RNFL thickness was associated with worse visual acuity (VA). Patients with normal RNFL had a median VA of 20/200 while those with thin RNFL had to count their fingers (CF). The patients with normal pre-operative RNFL had a significant improvement in median VA after surgery, from 20/200 to 20/32 (p=0.022), whereas the patients with thin RNFL did not improve (CF to CF, p=0.026). The patients with normal pre-operative GCL-IPL had non-significant improvement in median VA after surgery from CF to 20/20 (p=0.505), also the patients with thin GCL-IPL from CF to 20/200 (p=0.151). Conclusion: The visual recovery after pituitary adenoma surgery is likely to be predicted by pre-operative OCT RNFL. Patients with normal RNFL thickness show an increased tendency in visual recovery after surgery. Keywords: Optical coherence tomography , visual acuity, pituitary adenoma
Swollen Disc in Children : Diagnostic Approach Prihatningtias, Riski
Majalah Oftalmologi Indonesia Vol 49 No S1 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/y6tekc65

Abstract

Swollen disc is a clinical sign of eye disease, neurological or systemic. It happened because of the increase in intracranial. Some of the conditions that cause swollen disc are optic neuritis, optic neuropathy, retinal vein occlusion, papilloedema, or pseudo-disc swelling (e.g drusen). In children, the incidence of swollen discs differs from that in adults. Diagnosis can be made using OCT (Optical Coherence Tomography), ocular ultrasound, VEP (Visual Evoked Potential) and MRI (Magnetic Resonance Imaging) of the orbit and head
COMPARATIVE VALIDITY OF LEA CONTRAST SENSITIVITY CHART TO PELLI-ROBSON CONTRAST SENSITIVITY CHART IN NEURO-OPHTHALMOLOGY PATIENTS Valencia, Lovenia; Prihatningtias, Riski
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/ahbbs726

Abstract

INTRODUCTION AND OBJECTIVEThe Pelli-Robson and LEA contrast sensitivity chart are widely used to measure clinical contrastsensitivity. The Pelli-Robson is a gold standard with the limitation of its bulky size. The LEAcontrast sensitivity chart offers a reliable test in a way more practical and portable chart. Thiscondition led to a question of whether we can predict Pelli-Robson score based on the LEA score.This study developed a conversion method to facilitate the transition from the LEA to the PelliRobson and validating the conversion score. METHODSThis study retrospectively examined the relationship between LEA and Pelli-Robson ContrastSensitivity Test. There were 120 eyes included in this study. We produced a conversion tableusing the equipercentile equating method. Then, we evaluated the reliability and accuracy of thisalgorithm to convert the LEA to the Pelli-Robson contrast sensitivity score. RESULTSLEA scores were converted to Pelli-Robson scores according to a conversion table that achieveda reliability of 0.91 based on intraclass correlation. The accuracy of this algorithm was 81.6%within 1 point difference from the raw score. CONCLUSIONSThis study reported a reliable and comparable conversion algorithm for transforming LEA scoresinto converted estimated Pelli-Robson scores. This method will enhance the utility of existing datain clinical and research settings.
Co-Authors Arief Wildan, Arief Astuti, Ratih Kusuma Dhafira, Farhana Fifin Luthfia Rahmi Hermawan Istiadi Ivana Tanoko Lovenia Valencia, Lovenia Maharani Maharani, Maharani Nitihapsari, Galuh Yulieta Nugroho, Trilaksana Rahmi, Fifin L Rikiandraswida, Zahira Ryamizard, Rizal Ryan, Kevin Arfa Saubig, Arnila Novitasari Saubiq, Arnila Novitasari Syaqdiyah, Widya Halimatus Winarto Winarto