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All Journal Jurnal MIPA PHARMACON Jurnal Farmasi Medica (Pharmacy Medical Journal) PMJ Pharmacology and Clinical Pharmacy Research Jurnal Lentera Farma
ERLADYS MELINDAH RUMONDOR, ERLADYS MELINDAH
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Mathematics Medicine & Pharmacology Physics Public Health

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Journal : PHARMACON

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Assessment of Antioxidant Activity of Ethanol Extract from Callyspongia arizusa Obtained from Parentek Beach, Minahasa Regency Miracle Cristia Meyfi Bambulu; Adithya Yudistira; Erladys Melindah Rumondor
PHARMACON Vol. 13 No. 3 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55265

Abstract

Callyspongia aerizusa is one of the sponges that has compounds with high activity and has a porous body surface structure so that it is included in the phylum porifera. Antioxidants are compounds that work by binding free radicals so that they can inhibit oxidation reactions. This study aims to determine the antioxidant activity of Callyspongia aerizusa. This research is a laboratory experiment by testing the ethanol extract of Callyspongia aerizusa using DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The results of data analysis of % inhibition were 48.9% (100 ppm), 51.09% (120 ppm), 51.32% (140 ppm), 52.00% (160 ppm), and 53.73% (180 ppm). The highest antioxidant activity was achieved at a concentration of 180 ppm with a percent inhibition of 53.73%. This shows that the sample of Callyspongia aerizusa obtained from Parentek Beach, Minahasa Regency has antioxidant activity
Antibacterial Activity Test of Lissoclinum patella Extract Obtained from the Coastal Waters of Parentek Village, East Lembean District, Minahasa Regency Kiwol, Hilda; Wewengkang, Defny; Rumondor, Erladys
PHARMACON Vol. 13 No. 3 (2024): PHARMACON
Publisher : UNIVERSITAS SAM RATULANGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/pha.13.2024.55990

Abstract

Ascidians are a class of marine tunicates that are included in marine invertebrate organisms. Tunicates (Ascidian) are animals included in the subphylum Urochordata, which have a small bag-like body shape and generally live in marine waters. The body of this animal is covered by a coat (tunic) formed from protein and polysaccharide compounds. This study aims to determine the antibacterial activity of ethanol extract of ascidian Lissoclinum patella against the growth of Staphylococcus aureus and Escherichia coli bacteria. Extraction uses maceration method to extract active compounds from ascidian Lissoclinum patella. The results of the extract were tested whether there was antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria, the test used the Kirby-Bauer agar diffusion method. The results of the test showed antibacterial activity with a marked inhibition zone around the disc paper of the extract test solution on Staphylococcus aureus bacteria with a medium inhibition zone diameter of 7.6 mm and Escherichia coli bacteria with a medium inhibition zone diameter of 6.3 mm.
Co-Authors Adithya Yudistira Agow, Mikhael C. Alfiani Idie Barliana, Melisa I. Berlian Tasya Tumundo Billy Arthur Porajow Brian G. A. Adilan Bryan Andrew Tikonuwu Bunet, Greey C.E. Christo Togelang Datu, Olvie S. Datu, Olvie Syenni Defny Silvia Wewengkang Edi, Hosea Jaya Elly Suoth Fatimawali . Gayatri Citraningtyas Grafland Langkay Henki Rotinsulu, Henki Hermelina Yosephina Burdam Herni I. E. Simbala Herny E.I. Simbala Hosea J. Edy, Hosea J. Idie, Alfiani Ira Handayani Puspita Prins Jabes Wolter Kanter Julianri Sari Lebang, Julianri Sari Karlah L. R. Mansauda Kevin R. Mengko Kinanti, Agata Mega Kindangen, Eunike Elizabeth Kiwol, Hilda Komang Ayu May Widyani Laleno, Ellysa N. Lampongajo, Stela Mahdalena Lontaan, Gloria J. Lumbu, Alisa W. R. Lumentut, Natalia Luntungan, Brigita Michelle Luy Parala Marampung, Wahyuni Melisa I. Barliana Melisa Oktafiani Makalunsenge Miracle Cristia Meyfi Bambulu Moelyono Moektiwardoyo Moelyono Moektiwardoyo, Moelyono Mohtar, Khumairah Nadine Natari Pangemanan, Stephany P. Rolos, Tesalonika N. Rondonuwu, Greifen Triky Sambou, Christel N. SELLYANA MAHARANI BAWEKES Shalomyta Monangin Tawalujan, Wulan P. Trina E. Tallei, Trina E. Tumundo, Berlian Tasya Viocindy Riska Nusaly Viska Fadila Tompunu Widya Astuty Lolo, Widya Astuty Wiranatika Jhonatan Sangkoy Yulien C. Sambode