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All Journal IDJP (Indonesian Journal of Pharmaceutics) Journal of The Indonesian Society of Integrated Chemistry
Yoga Windu Wardhana, Yoga Windu
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Chemical Engineering, Chemistry & Bioengineering Chemistry Education

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Quantitative Analysis of Mineral in Seawater Concentrate from Pamekasan, Madura Using XRF and ICP-OES Methods Hartesi, Barmi; Wardhana, Yoga Windu; Muhaimin, Muhaimin; Sriwidodo, Sriwidodo; Khairinisa, Miski Aghnia; Dewi, Mayang Kusuma; Chaerunisaa, Anis Yohana
Journal of The Indonesian Society of Integrated Chemistry Vol. 16 No. 1 (2024): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v16i1.34656

Abstract

Seawater concentrate from Pamekasan is a product with high mineral content. The mineral content analysis of Pamekasan seawater concentrate was conducted using a comparative test of results from X-Ray Fluorescence Spectrometry (XRF) and Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). This mineral content testing used a skin moisture device. The essential minerals found in Pamekasan seawater concentrate through analysis are Mg, Cl, K, Ca, Cr, Mn, Cu, and Zn. Statistical analysis results from XRF and ICP-OES on market products showed no significant difference in average results; however, there was a significant difference in average results in the samples. The most recommended method for analyzing seawater mineral concentrate from Pamekasan is ICP-OES due to its wider detection range and lower matrix interference.
Formulation and Evaluation Of Black Garlic (Allium Sativum L.) Lozenges As An Antioxidant Supplement Putriana, Norisca Aliza; Mardawati, Efri; Wardhana, Yoga Windu; Ismiatun, Ismiatun; Wulandari, Anting; Wira, Dwi Wahyudha; Masruchin, Nanang
Indonesian Journal of Pharmaceutics Vol 4, Issue 1, Jan - April 2022
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v4i1.40477

Abstract

Free radicals are species of reactive chemical compounds that can cause degenerative diseases. Antioxidants work to deactivate free radicals by binding to these radicals to stabilize the radicals. One of the plants that contain antioxidants is black garlic. This study aimed to obtain the best formula from the preparation of lozenges of black garlic extract using the wet granulation method as an antioxidant supplement. The formula optimization was carried out using a statistical approach with a two-level factorial method using expert design software. The lozenges formula was made using wet granulation method. The granules and tablets were evaluated for its characteristic. Besides, the levels of polyphenols and antioxidant activity of the extracts and lozenges were also determined. The best formula is F2 obtained from a ratio of gum arabic and starch pregelatin of 3: 5 with a desirability value of 0.922. The Evaluation of black garlic extract granules is eligible, including the moisture content of 2.04%, an excellent flow rate is 18.3 g/s, and good compressibility of 9%. The uniformity of lozenge weight obtained is eligible, which is 3%. The hardness and disintegration time of  9.1 kg and 11.28 minutes, respectively. Meanwhile, the antioxidant activity of the extract and lozenges was 263 µg/mL and 323.9 µg/mL, respectively. The best formula obtained is with 3% gum arabic and 5% starch pregelatin.Keywords: Antioxidant, Black Garlic, Design expert, Lozenges 
Co-Authors Anis Yohana Chaerunisaa, Anis Yohana Barmi Hartesi Dwi Wahyudha Wira Efri Mardawati Ismiatun, Ismiatun Mayang Kusuma Dewi Miski Aghnia Khairinisa Muhaimin Muhaimin Nanang Masruchin Norisca Aliza Putriana Sriwidodo Sriwidodo Wulandari, Anting