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All Journal Farmaka Majalah Farmasetika Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Community Development Journal: Jurnal Pengabdian Masyarakat Journal of The Indonesian Society of Integrated Chemistry Jurnal Farmasi Galenika
Mayang Kusuma Dewi
Faculty Of Pharmacy, Universitas Padjadjaran
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Peptida Antimikrobial Cathelicidin dan Liposom sebagai Pembawa Mayang Kusuma Dewi; Anis Yohana Chaerunisaa; Sriwidodo Sriwidodo
Majalah Farmasetika Vol 6, No 2 (2021): Vol. 6, No. 2, Tahun 2021
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/mfarmasetika.v6i2.33182

Abstract

Peptida antimikrobial (PAM) dalam beberapa tahun terakhir telah menarik perhatian di kalangan ilmuwan, profesional kesehatan, dan perusahaan farmasi karena potensi terapeutiknya yang sangat luas. Cathelicidin merupakan salah satu kelompok dari PAM dengan berat molekul rendah yang mempunyai berbagai aktivitas biologis pada rentang terapi tertentu yang berfungsi sebagai antimikrobial, antivirus, dan antijamur, serta dapat memodulasi sistem imum terhadap infeksi bakteri (gram positif dan gram negatif). Walaupun menarik untuk aplikasi klinis, cathelicidin memiliki keterbatasan dalam hal stabilitas dan aktivitasnya secara in-vivo, serta interaksi non-spesifik dengan membran biologis inang yang mengarah pada efek sitotoksik yang merugikan. Enkapsulasi cathelicidin dapat mengakibatkan penurunan sitotoksisitas, meningkatkan stabilitas dan aktivitas biologisnya. Keterbatasan cathelicidin dapat diatasi dengan mengenkapsulasi cathelicidin dalam pembawa lipid seperti liposom. Review ini bertujuan untuk memberikan gambaran singkat mengenai struktur, sifat, fungsi, uji klinis, dan keterbatasan dari cathelicidin yang mana keterbatasan cathelicidin ini dapat di atasi dengan pembawa vesikular salah satunya adalah liposom. Liposom merupakan pembawa vesikular generasi pertama yang bersifat non-toksik, biodegradable, biokompatibel, dan stabil dalam larutan koloid sistem penghantaran obat. Sistem liposom dapat melindungi peptida yang dienkapsulasi dari degradasi protease. Selain itu, pembawa liposom disajikan sebagai alternatif yang menjanjikan untuk mengoptimalkan pemberian cathelicidin dalam hal dosis, pola pengiriman, dan keamanan.
Artikel Review : Diagnosis dan Regimen Pengobatan Skabies MAYANG KUSUMA DEWI; Nasrul Wathoni
Farmaka Vol 15, No 1 (2017): Suplemen
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (67.208 KB) | DOI: 10.24198/jf.v15i1.12898

Abstract

Abstrak Skabies merupakan suatu penyakit kulit menular yang disebabkan oleh infeksi tungau Sarcoptes scabiei. Infeksi tungau ini dapat menyebabkan gatal-gatal yang sangat hebat. Skabies ditandai dengan lesi. Terdapat dua lesi pada skabies yaitu lesi spesifik (liang atau terowongan) dan lesi nonspesifik (papula, vesikel dan ekskoriasi). Tempat  khas dari tubuh yang biasanya tekena skabies adalah jari-jari, pergelangan tangan, lipatan aksila, perut, bokong, dan alat kelamin. Riview artikel ini bertujuan untuk mengetahui beberapa macam metode diagnosis dan pilihan terapi yang tepat pada skabies. Diagnosis pasti dapat dilakukan dengan cara preparasi KOH, biopsi, dermoskopi dan pembesaran fotografi digital, serta burrow ink test (BIT). Pengobatan skabies dapat dilakukan secara oral maupun topikal. Ivermektin digunakan secara oral sedangkan permetrin, lindane, benzyl benzoate, crotamiton dan sulfur yang diendapkan digunakan secara topikal. Berdasarkan beberapa penelitian, pengobatan lini pertama skabies adalah dengan obat topikal krim permetrin 5%.
Use of MOCAF flour as raw material for healthy and hygienic lakar crackers in N&N MSMEs Muhaimin Muhaimin; Anis Yohana Chaerunisaa; Tiana Milanda; Intan Timur Maisyarah; Uce Lestari; Mayang Kusuma Dewi; Lia Mardiana; Karina Erlianti
Abdimas: Jurnal Pengabdian Masyarakat Universitas Merdeka Malang Vol 8, No 4 (2023): November 2023
Publisher : University of Merdeka Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26905/abdimas.v8i4.11237

Abstract

In the vicinity of NN Micro, Small, and Medium Enterprises (MSME) in Jatiroke Village, Sumedang, West Java, cassava plantations abound, yet their harvest is often undervalued and sold at low prices. To enhance economic value, cassava from Jatiroke Village is now being processed into Modified Cassava Flour (MOCAF) for use as a primary ingredient in lakar cracker production at NN MSME. Previously, wheat and tapioca flours were sourced from the market for cracker production. The objective of this Community Partnership Empowerment (CPE) initiative is to replace wheat flour with locally processed MOCAF, diversifying food ingredient sources using available resources. MOCAF is not only gluten-free but is also deemed safe for consumption, especially for those with autoimmune diseases, memory loss, and autism. The CPE program includes training on MOCAF flour production and hands-on experience in making lakar crackers with MOCAF as a core ingredient. This comprehensive effort aims to promote NN MSME's growth by incorporating innovative technology for the production of healthy and hygienic crackers, thereby benefiting public health, particularly individuals with autoimmune conditions. This strategic shift not only holds economic promise but also contributes to the well-being of the community.
SOSIALISASI PEMANFAATAN PEWARNA ALAMI PADA PENGOLAHAN KERUPUK LAKAR DI UMKM N&N JATINANGOR Muhaimin, Muhaimin; Chaerunisaa, Anis Yohana; Milanda, Tiana; Maisyarah, Intan Timur; Lestari, Uce; Dewi, Mayang Kusuma; Mardiana, Lia; Erlianti, Karina
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 4 No. 5 (2023): Volume 4 Nomor 5 Tahun 2023
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v4i5.21970

Abstract

UMKM N&N yang berada di Desa Jatiroke, Kecamatan Jatinangor, Sumedang, Jawa Barat merupakan satu-satunya UMKM yang memproduksi kerupuk lakar dengan bahan dasar singkong. Awal produksi kerupuk lakar menggunakan pewarna makanan sintetis yang berada dipasaran. Mengingat bahayanya penggunaan pewarna sintetis pada makanan akan berdampak pada kesehatan manusia salah satunya adalah timbulnya reaksi alergi pada jangka waktu yang pendek dan timbulnya penyakit kanker pada jangka waktu yang lama. Oleh karena itu untuk menghindari pengunaan pewarna sintetis pada kerupuk lakar, maka tim PKM (Pemberdayaan Kemitraan Masyarakat) Universitas Padjadjaran Bandung mengadakan sosialisasi pemanfaatan pewarna alami yang berasal dari bahan alam seperti wortel (warna orange), buah naga (warna merah fanta), bayam (warna hijau) dan ubi ungu (warna ungu) untuk dijadikan pewarna pada pengolahan kerupuk lakar yang sehat dan hygienis. Adapun tujuan sosialisasi atau penyuluhan pada UMKM N&N adalah untuk mendapatkan produk kerupuk lakar yang sehat dan bebas dari pewarna sintetis, sehingga dapat meningkatkan daya tarik bagi konsumen untuk mengkonsumsinya. Hasil dari penyuluhan penggunaan pewarna alami pada makanan telah diterapkan oleh UMKM N&N pada pengolahan kerupuk lakar dengan penggunaan 4 pewarna alami seperti wortel, bayam, buah naga dan ubi ungu sehingga dapat menambah varian warna dari kerupuk lakar yang dihasilkan. Selain itu kegiatan PKM ini juga memberikan kebermanfaatan kepada UMKM N&N dengan bantuan kemasan kerupuk berupa standing pouch sehingga dapat menambah nilai jual kerupuk lakar dan dapat dijual pada pasar retail seperti minimarket dan supermarket. Kerupuk lakar yang diproduksi oleh UMKM N&N diberi nama merek dagang kerupuk lakar ANIA.
Quantitative Analysis of Mineral in Seawater Concentrate from Pamekasan, Madura Using XRF and ICP-OES Methods Hartesi, Barmi; Wardhana, Yoga Windu; Muhaimin, Muhaimin; Sriwidodo, Sriwidodo; Khairinisa, Miski Aghnia; Dewi, Mayang Kusuma; Chaerunisaa, Anis Yohana
Journal of The Indonesian Society of Integrated Chemistry Vol. 16 No. 1 (2024): Journal of The Indonesian Society of Integrated Chemistry
Publisher : Pendidikan Kimia FKIP Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jisic.v16i1.34656

Abstract

Seawater concentrate from Pamekasan is a product with high mineral content. The mineral content analysis of Pamekasan seawater concentrate was conducted using a comparative test of results from X-Ray Fluorescence Spectrometry (XRF) and Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). This mineral content testing used a skin moisture device. The essential minerals found in Pamekasan seawater concentrate through analysis are Mg, Cl, K, Ca, Cr, Mn, Cu, and Zn. Statistical analysis results from XRF and ICP-OES on market products showed no significant difference in average results; however, there was a significant difference in average results in the samples. The most recommended method for analyzing seawater mineral concentrate from Pamekasan is ICP-OES due to its wider detection range and lower matrix interference.
Pengaruh Variasi Konsentrasi Cocamidopropyl Betaine Pada Karakteristik Fisik Sampo Ekstrak Kering Teh Hijau Patihul Husni; Rini Silviya; Uswatul Hasanah; Mikhania Christiningtyas Eryani; Mayang Kusuma Dewi; Norisca Aliza Putriana; Melinda Januarti
JURNAL FARMASI GALENIKA Vol 13 No 1 (2026): Jurnal Farmasi Galenika Volume 13 No 1
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i1.435

Abstract

Hair growth–promoting preparations are used to prevent hair damage problems. Compounds contained in green tea extract have activity as hair growth promoters. This study aimed to obtain data on the effect of variations in cocamidopropyl betaine concentration on the physical characteristics of shampoo containing dry green tea extract. The formulations were prepared in three formulas (F1, F2, and F3) containing different concentrations of cocamidopropyl betaine (8.25%, 8.5%, and 8.75%). The research stages included formulation followed by physical evaluation, including organoleptic properties, homogeneity, pH, viscosity, and foam stability. The results showed that the shampoo preparations were viscous liquids, brown in color, with a characteristic odor, pH of 7–8, viscosity of 250–300 cPs, and foam stability of 15–20 cm. The conclusion of this study is that variations in cocamidopropyl betaine concentration affect the physical characteristics of shampoo containing dry green tea extract. The concentration of cocamidopropyl betaine greatly influences the physical stability of the shampoo, with F3 as the best formula based on physical evaluation, which contains 8.75% cocamidopropyl betaine.
Pengetahuan, Sikap, dan Perilaku Mahasiswa Prodi Non Kesehatan Universitas Padjadjaran Pada Penggunaan Produk Kosmetik Halal Norisca Aliza Putriana; Muhammad Dimas; Patihul Husni; Mayang Kusuma Dewi; Soraya Ratnawulan Mita
JURNAL FARMASI GALENIKA Vol 13 No 2 (2026): August 2026
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v13i2.444

Abstract

In Indonesia, cosmetic products are required to obtain halal certification, as stipulated in Law No. 33 of 2014 on Halal Product Assurance (Jaminan Produk Halal/JPH), which states that the government is responsible for implementing the halal assurance system. This requirement is further reinforced by Article 141 of Government Regulation No. 39 of 2021, which regulates the mandatory halal certification of cosmetic products until October 17, 2026. One of the challenges in halal certification for cosmetics is the use of imported raw materials whose halal status cannot always be guaranteed. This condition may influence consumers’ decisions regarding the selection and use of halal cosmetic products. This study aimed to assess the knowledge, attitudes, and behaviors of non-health students at Universitas Padjadjaran regarding the use of halal cosmetic products. A descriptive cross-sectional study was conducted using an online questionnaire. A total of 248 students aged ≥18 years were consecutively recruited, and data were collected from April to May 2023. Data were analyzed using the chi-square, Kruskal-Wallis, and Spearman’s rho tests with SPSS version 28. The results showed that 59.27% of non-health students had a positive level of knowledge regarding halal cosmetic products. More than half of the respondents demonstrated positive attitudes and behaviors toward the use of halal cosmetics, with percentages of 56.45% and 60.89%, respectively. Age was significantly associated with behavior in usage decisions (p=0.008; OR=1.607; 95% CI: 0.939–2.751). Faculty differences were also significantly associated with knowledge (p=0.006), attitudes (p<0.001), and behavior in usage decisions (p=0.005). Overall, non-health students at Universitas Padjadjaran demonstrated positive tendencies in knowledge, attitudes, and behaviors toward halal cosmetics, with positive correlations among these variables in their decisions to use halal cosmetic products.
Co-Authors Anis Yohana Chaerunisaa Anis Yohana Chaerunisaa, Anis Yohana Barmi Hartesi Erlianti, Karina Eryani, Mikhania Christiningtyas Intan Timur Maisyarah Karina Erlianti Lia Mardiana Melinda Januarti Miski Aghnia Khairinisa Muhaimin Muhaimin Muhaimin Muhaimin Muhammad Dimas Nasrul Wathoni Norisca Aliza Putriana Patihul Husni Rini Silviya Soraya Ratnawulan Mita Sriwidodo Sriwidodo TIANA MILANDA Uce Lestari Uce Lestari Uswatul Hasanah Yoga Windu Wardhana, Yoga Windu