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All Journal Medula Manuju : Malahayati Nursing Journal JK Unila (Jurnal Kedokteran Universitas Lampung) MAHESA : Malahayati Health Student Journal Nusantara Hasana Journal Journal of Innovative and Creativity Journal of Dietetics Science Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Anisa Nuraisa Jausal
Universitas Lampung
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Ewing Sarkoma: Ulasan Singkat Keganasan: Indonesia Rafi Gutra Aslam; Helmi Ismunandar; Risal Wintoko; Exsa Hadibrata; Anisa Nuraisa Jausal
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.336

Abstract

A malignancy that identified first by James Ewing in 1921. Ewing sarcoma is a malignancy of the bones caused by abnormal activity of progenitor cell mesenchymal occurs by a genetic factor where the patient had a combination of translocation chromosome non-random in t(11; 22) (q24;q12) or t(21; 22) (q22; q12). The patient will have pathognomonic findings of periosteal reaction similar to "Onion skin", lesions like “Moth-eaten”, and “Codman’s Triangle” in radiology findings. Second highest malignancy bone prevalent worldwide after osteosarcoma. This malignancy occurs commonly in the male gender, incidence peaked in the approximately first decade in life with a prognosis range of about 5 years more or less. The malignancy occurs in the metaphysis-diaphysis part of the bone that has a variety of prognoses based on stage, metastasis, and therapy. Literature Review method is used in this article writing by article, journal, and book that review shortly about Ewing sarcoma from multi-aspect of etiology, epidemiology, pathogenesis and pathophysiology, clinical manifestations, treatment, staging, prognosis, complication, and education as the last topic. Prognosis of Ewing Sarcoma patient will be better if given multimodal therapy including chemotherapy, radiotherapy, and operation that adjusted with the condition in every patient. Nevertheless, further research is needed about best treatment in goals to extend patient survivability and enhance prognoses approximately in 3 years.
Hubungan antara kebiasaan membersihkan telinga dengan timbulnya otitis eksterna pada pasien RSUD dr. A. Dadi Tjokrodipo Muhammad Iqbal Ramadhan; Mukhlis Imanto; Anisa Nuraisa Jausal; Asep Sukohar
Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine Vol. 11 No. 2 (2024): Jurnal Kesehatan dan Agromedicine
Publisher : Fakultas Kedokteran Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jka.v11i2.pp114-120

Abstract

Otitis eksterna merupakan inflamasi pada telinga bagian luar yang disertai infeksi atautanpa infeksi. penyebab yang paling umum adalah bakteri. Otitis eksterna sering kali terjadi saatmusim panas dan iklim yang hangat serta lembab. Indonesia menempati posisi keempatprevalensi tertinggi gangguan pendengaran di Asia Tenggara yaitu sebesar 4,6%, denganprevalensi tertinggi yaitu negara Sri Langka (8,8%), Myanmar (8,4%), dan India (6,3%). Tujuanpenelitian ini untuk mengetahui hubungan pengetahuan kebiasaan membersihkan telingadengan otitis eksterna dan juga hubungan antara pengetahuan benda pembersih telinga denganotitis eksterna menggunakan metode kuesioner tertutup. Metode desain penelitian analisisobservasional dengan pendekatan cross-sectional jumlah sampel dalam penelitian ini adalah106 sampel. Pengumpulan data dilakukan dengan menggunakan data primer. Data diperolehdari kuesioner. Berdasarkan analisis bivariat, ditemukan hubungan antara pengetahuankebiasaan membersihkan telinga dengan otitis eksterna di dapatkan hasil 0,003. Ada hubunganantara kebiasaan membersihkan telinga dengan timbulnya otitis eksternaKata kunci: Faktor Timbulnya Otitis Eksterna, Kebersihan Telinga
Chronic Kidney Disease Of Unknown Etiology (CKDU) Pada Populasi Petani Di Asia: Peran Biomarker Cedera Tubulus Dalam Deteksi Dini (Narrative Review) Nashwa Amirul Haq Azzuhri; Ade Yonata; Anisa Nuraisa Jausal; Iswandi Darwis
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.6121

Abstract

Tujuan penelitian ini adalah untuk memberikan tinjauan komprehensif mengenai penyakit ginjal kronik dengan etiologi tidak diketahui atau chronic kidney disease of unknown etiology (CKDu) pada populasi petani di Asia, dengan penekanan pada karakteristik epidemiologis, faktor risiko multifaktorial, serta potensi biomarker cedera tubulus sebagai alat deteksi dini. CKDu merupakan masalah kesehatan masyarakat yang semakin meningkat dan sering terdiagnosis pada stadium lanjut akibat keterbatasan parameter ginjal konvensional dalam mendeteksi cedera ginjal subklinis. Bahan dan metode yang digunakan dalam penelitian ini berupa narrative review terstruktur. Penelusuran literatur dilakukan melalui basis data PubMed dan Google Scholar terhadap publikasi yang diterbitkan dalam kurun waktu 2015–2025. Artikel yang memenuhi kriteria inklusi diseleksi berdasarkan fokus pada CKDu di komunitas pertanian, faktor risiko lingkungan dan okupasional, serta penggunaan biomarker ginjal. Data yang relevan diekstraksi dan dianalisis menggunakan pendekatan sintesis naratif tematik. Hasil tinjauan menunjukkan bahwa CKDu terutama menyerang pekerja pertanian laki-laki usia produktif dan ditandai oleh perjalanan penyakit yang sering asimtomatik, proteinuria minimal, serta gambaran histopatologi berupa nefritis tubulointerstisial kronik. Faktor risiko utama yang berperan meliputi stres panas dan dehidrasi berulang, paparan agrokimia, serta kontaminan lingkungan. Sejumlah studi melaporkan peningkatan biomarker cedera tubulus, terutama kidney injury molecule-1 (KIM-1) dan neutrophil gelatinase-associated lipocalin (NGAL), pada individu dengan rasio albumin terhadap kreatinin yang masih normal, serta asosiasinya dengan penurunan laju filtrasi glomerulus yang lebih cepat. Kesimpulan dari narrative review ini menunjukkan bahwa biomarker cedera tubulus memiliki potensi besar sebagai alat deteksi dini CKDu pada populasi berisiko tinggi. Namun, penerapannya masih menghadapi kendala berupa keterbatasan biaya, belum adanya standardisasi metode, dan minimnya infrastruktur laboratorium. Oleh karena itu, diperlukan penelitian lanjutan untuk validasi prognostik jangka panjang serta pengembangan metode pemeriksaan yang lebih aplikatif dan terjangkau, khususnya di wilayah dengan sumber daya terbatas.
PENGARUH KONSUMSI KOPI TERHADAP PENINGKATAN RISIKO KEJADIAN HIPERTENSI: LITERATURE REVIEW Naila Fathiya Isnanto; Sutarto Sutarto; Anisa Nuraisa Jausal; Dian Isti Angraini
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.8088

Abstract

Latar Belakang: Hipertensi (tekanan darah sistolik ≥140 mmHg dan/atau diastolik ≥90 mmHg) menjadi krisis kesehatan global dengan 1,13 miliar kasus, sementara di Indonesia prevalensinya 29,2-30,8%. Tren konsumsi kopi meningkat di tengah perdebatan perannya sebagai faktor risiko hipertensi melalui vasokonstriksi akibat kafein. Tujuan: Tinjauan ini menganalisis pengaruh konsumsi kopi terhadap risiko hipertensi. Metode: Tinjauan pustaka kualitatif dari Google Scholar dan PubMed (2020-2025) dengan kata kunci "hipertensi," "tekanan darah," "konsumsi kopi." Populasi seluruh studi relevan nasional/internasional; sampel 10 artikel terpilih berdasarkan kriteria inklusi. Instrumen tabel analisis literatur; analisis deskriptif-komparatif dengan model Emzir. Hasil: Enam studi tunjukkan hubungan signifikan positif (p<0,05), terutama ≥3 cangkir/hari pada lansia (kenaikan SBP/DBP 5-15 mmHg); empat studi tidak temukan hubungan akibat toleransi kafein. Kesimpulan: Konsumsi kopi sedang-tinggi tingkatkan risiko hipertensi pada kelompok rentan, meski bervariasi berdasarkan dosis dan demografi.
Efek Protektif Ekstrak Daun Jambu Air (Syzygium Aqueum) terhadap Kerusakan Lambung Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar yang Diinduksi Indometasin Adilla Justisia; Susianti Susianti; Anisa Nuraisa Jausal; Hendri Busman
Malahayati Nursing Journal Vol 7, No 8 (2025): Volume 7 Nomor 8 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i8.21126

Abstract

ABSTRACT The prevalence of peptic ulcers caused by the use of Nonsteroidal Anti-Inflammatory Drugs (NSAID) has increased over the past 10 years. Oxidative stress induced by NSAID can trigger the formation of peptic ulcers. The objective of this research was to determine the protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) wistar strain induced by indomethacin. This laboratory experimental study with a randomized post-test only control group design involved 24 male Wistar strain white rats divided into 6 groups. Group K(0) was given food and water, K(-) was administered indomethacin at a dose of 30 mg/kgBW, K(+) received vitamin C at a dose of 9 mg/kgBW and indomethacin at 30 mg/kgBW, while P1, P2, and P3 were given water apple leaf extract at doses of 100 mg/kgBW, 300 mg/kgBW, and 900 mg/kgBW, along with indomethacin at 30 mg/kgBW. The results of the Mann-Whitney statistical test analysis showed a significant difference (p0.05) between group K(-), which was administered only indomethacin, and group P2 and P3, which were administered extracts of water apple leaf at doses of 300 mg/kgBW and 900 mg/kgBW along with indomethacin at 30 mg/kgBW. There is an protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) Wistar strain induced by indomethacin. Keywords: Water Apple Leaf, Syzygium Aqueum, Antioxidants, Indomethacin, Peptic Ulcer  ABSTRAK Prevalensi ulkus peptikum yang disebabkan oleh penggunaan Nonsteroidal Anti-Inflammatory Drugs (NSAID) mengalami peningkatan dalam kurun waktu 10 tahun. Stres oksidatif yang disebabkan oleh NSAID dapat memicu terbentuknya ulkus peptikum. Tujuan penelitian ini untuk mengetahui efek protektif ekstrak daun jambu air (Syzygium aqueum) terhadap kerusakan lambung tikus putih jantan (Rattus norvegicus) galur wistar yang diinduksi indometasin. Penelitian eksperimental laboratorik dengan rancangan randomized post-test only control group ini menggunakan 24 tikus putih jantan galur Wistar yang dibagi ke dalam 6 kelompok. K(0) diberikan makan dan minum, K(-) diberikan indometasin 30 mg/kgBB, K(+) diberikan vitamin C 9 mg/kgBB dan indometasin 30 mg/kgBB, serta P1, P2, P3 diberikan ekstrak daun jambu air dengan dosis berturut-turut 100 mg/kgBB, 300 mg/kgBB, 900 mg/kgBB dan indometasin 30 mg/kgBB. Hasil analisis uji statistik Mann-Whitney didapatkan perbedaan bermakna (p0.05) antara kelompok K(-) yang hanya diberikan indometasin dengan kelompok P2 dan P3 yang diberikan ekstrak 300 mg/kgBB dan 900 mg/kgBB serta indometasin 30 mg/kgBB. Ekstrak daun jambu air (Syzygium aqueum) memberikan efek protektif terhadap kerusakan lambung tikus putih (Rattus norvegicus) jantan galur Wistar yang diinduksi indometasin. Kata Kunci: Daun Jambu Air, Syzygium aqueum, Antioksidan, Indometasin, Ulkus Peptikum
Hubungan Faktor Sosiodemografi dengan Kejadian Anemia Mikrositik Hipokromik pada Ibu Hamil di RSIA Permata Bunda Kabupaten Pandegelang Muhammad Fauzan Iqbal; Sutarto Sutarto; Anisa Nuraisa Jausal; Rodiani Rodiani; Reni Indriyani
Journal of Dietetics Science Vol. 2 No. 1 (2026): Journal of Dietetics Science
Publisher : Nutrition Department, Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jds.v2i1.5673

Abstract

Anemia in pregnant women remains a significant public health problem and contributes to increased maternal and fetal morbidity and mortality. Microcytic hypochromic anemia is the most common type of anemia during pregnancy and is associated with various factors, including sociodemographic characteristics. This study aimed to analyze the association between sociodemographic factors and microcytic hypochromic anemia status among pregnant women at Permata Ibunda Mother and Child Hospital, Pandeglang Regency, in 2024. This study used an analytical observational design with a case-control approach. A total of 74 pregnant women were included and divided into case and control groups based on anemia status. Data were obtained from medical records and analyzed using the Chi-Square test with a significance level of 0.05. The results showed that age (p=0.027), education (p=0.032), healthcare class (p=0.035), and residential area (p=0.030) were significantly associated with microcytic hypochromic anemia, while occupation (p=0.127) was not significantly associated. Pregnant women with non-ideal age, lower educational level, lower healthcare class, and those living in rural areas had a higher risk of developing anemia. In conclusion, certain sociodemographic factors are associated with the occurrence of microcytic hypochromic anemia among pregnant women. Therefore, comprehensive interventions through health education, improved access to healthcare services, and enhancement of socioeconomic conditions are needed to reduce the prevalence of anemia in pregnant women.
Peran Teknologi dalam Meningkatkan Kesehatan Masyarakat: Evaluasi Model Bisnis Halodoc sebagai Platform Telemedicine: Waluyo Rudiyanto, Anisa Nuraisa Jausal, Nabeel Muhammad, Rasha Andhika Satria, Malik Ahza Nugroho Waluyo Rudiyanto; Anisa Nuraisa Jausal; Nabeel Muhammad; Rasha Andhika Satria; Malik Ahza Nugroho
Jurnal Kedokteran Universitas Lampung Vol. 10 No. 1 (2026): JK Unila
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jkunila.v10i1.pp1-12

Abstract

This study aims to evaluate the role of technology in improving public health through Halodoc’s business model as a telemedicine platform in Indonesia, as well as analyze regulatory challenges, data security, and user trust. This research employs a qualitative method with a case study approach and systematic literature analysis. Data were collected through in-depth review of scientific literature, case study implementation of Halodoc, and analysis of telemedicine regulatory policies in Indonesia. The analysis focuses on the impact of telemedicine adoption, platform business models, and implementation challenges during and post-COVID-19 pandemic. Halodoc plays a significant role in expanding access to healthcare services, particularly in urban areas. The platform integrates online medical consultations, digital prescription provision, and medication delivery within an efficient ecosystem. During the COVID-19 pandemic, Indonesian telemedicine users surged from 2 million (2019) to 20 million (2020), demonstrating extraordinary growth. However, research reveals critical challenges including regulatory ambiguity for P2P (provider-to-patient) models, concerns about personal data security, access disparities between urban and rural areas, and limited user trust in online diagnosis without physical examination. Although Halodoc has proven its value proposition in improving healthcare efficiency and accessibility, continuous integration into the national health system requires strengthened comprehensive regulation, standardized data security, and strategic collaboration between public and private sectors. The government needs to develop clear telemedicine policies to maximize the potential of digital platforms in creating an inclusive and sustainable healthcare ecosystem.
DUAL OREXIN RECEPTOR ANTAGONIST (DORA) SEBAGAI TERAPI INSOMNIA: SEBUAH TINJAUAN PUSTAKA Dianda Faradiba Wardani; Oktafany Oktafany; Anisa Nuraisa Jausal; Oktadoni Saputra
Nusantara Hasana Journal Vol. 5 No. 8 (2026): Nusantara Hasana Journal, January 2026
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i8.1832

Abstract

Insomnia affects more than 852 million adults worldwide and 43.7% of individuals aged ≥19 years in Indonesia, highlighting the need for effective and safe therapy. Benzodiazepines and Z-drugs are commonly used but are associated with risks of tolerance and dependence. Dual orexin receptor antagonists (DORAs) have emerged as a more selective therapeutic alternative. A systematic literature review was conducted using PubMed and Google Scholar, focusing on meta-analyses of suvorexant, lemborexant, and daridorexant. Suvorexant improved subjective total sleep time (MD −19.10), subjective time to sleep onset (MD −8.23), and subjective wake after sleep onset (MD −6.45). Lemborexant at doses of 5–10 mg was effective in improving wake after sleep onset (MD −19.90; −22.24) and sleep onset latency (MD −9.23; −12.56). Daridorexant at doses of 25–50 mg reduced wake after sleep onset (MD −0.30; −0.53) and latent persistent sleep (MD −0.30; −0.53). Adverse effects of DORAs include somnolence, daytime sleepiness, fatigue, abnormal dreams, and nasopharyngitis. Overall, DORAs demonstrated significant effectiveness on subjective sleep parameters compared with control groups, with variations in effect size and safety profiles. DORAs may be considered effective and safe treatments for insomnia, with drug and dose selection tailored to clinical needs.
Pengaruh Tingkat Kepuasan Penggunaan Rekam Medis Elektronik dan Beban Kerja Terhadap Risiko Burnout pada Dokter di Rumah Sakit Tipe C Kabupaten Pesawaran Hasyim Adhafizh Sofyan; T.A Larasati; Anisa Nuraisa Jausal
MAHESA : Malahayati Health Student Journal Vol 6, No 9 (2026): Volume 6 Nomor 9 (2026)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v6i9.24715

Abstract

ABSTRACT The implementation of Electronic Medical Records (EMR) is part of the digital transformation of healthcare services aimed at improving efficiency and quality of care. However, in practice, EMR use may increase physicians’ administrative workload and potentially contribute to burnout. Type C hospitals in Pesawaran Regency have implemented EMR, yet evaluations of user satisfaction and its association with workload and burnout risk among physicians remain limited. This quantitative cross-sectional study was conducted from October to December 2025 at RSUD Pesawaran and RSU Gladish Medical Center Pesawaran. A total of 64 physicians were included using total sampling. EMR satisfaction was assessed using the End User Computing Satisfaction (EUCS) questionnaire, workload was measured using the RAW NASA-TLX, and burnout risk was evaluated using the Maslach Burnout Inventory–Human Services Survey (MBI-HSS). Data were analyzed using univariate and bivariate analyses with the Chi-square test. Most respondents reported being satisfied with EMR use (65.6%). The majority of physicians experienced moderate (39.1%) to high (37.5%) workload. Burnout risk was predominantly categorized as mild (65.6%) and moderate (34.4%), with no cases of severe burnout identified. Bivariate analysis showed no significant association between EMR satisfaction and burnout risk (p=0.177), nor between workload and burnout risk (p=0.374). EMR satisfaction and workload were not significantly associated with burnout risk among physicians in Type C hospitals in Pesawaran Regency. Keywords: Electronic Medical Records, Workload, Burnout, Physicians.  ABSTRAK Implementasi Rekam Medis Elektronik (RME) merupakan bagian dari transformasi digital pelayanan kesehatan yang bertujuan meningkatkan efisiensi dan mutu layanan. Namun, penggunaan RME berpotensi menambah beban kerja administratif dokter dan memengaruhi risiko burnout. Di rumah sakit tipe C Kabupaten Pesawaran, evaluasi terkait kepuasan penggunaan RME serta hubungannya dengan beban kerja dan risiko burnout pada dokter masih terbatas. Penelitian ini menggunakan desain kuantitatif cross-sectional yang dilaksanakan pada Oktober–Desember 2025 di RSUD Pesawaran dan RSU Gladish Medical Center Pesawaran. Sampel penelitian melibatkan 64 dokter yang diambil dengan teknik total sampling. Kepuasan penggunaan RME diukur menggunakan kuesioner End User Computing Satisfaction(EUCS), beban kerja menggunakan RAW NASA-TLX, dan risiko burnout menggunakan Maslach Burnout Inventory Human Services Survei (MBI-HSS). Analisis data dilakukan secara univariat dan bivariat menggunakan uji Chi-Square. Sebagian besar responden menyatakan puas terhadap penggunaan RME (65,6%). Beban kerja dokter paling banyak berada pada kategori sedang (39,1%) dan berat (37,5%). Risiko burnout mayoritas berada pada kategori ringan (65,6%) dan sedang (34,4%). Analisis bivariat menunjukkan tidak terdapat hubungan yang bermakna antara kepuasan penggunaan RME dengan risiko burnout (p=0,177) maupun antara beban kerja dengan risiko burnout (p=0,374). Tingkat kepuasan penggunaan RME dan beban kerja tidak berhubungan secara signifikan dengan risiko burnout pada dokter di rumah sakit tipe C Kabupaten Pesawaran. Kata Kunci:  Rekam Medis Elektronik, Beban Kerja, Burnout, Dokter.
Co-Authors ade yonata Adilla Justisia Asep Sukohar Dian Isti Angraini Dianda Faradiba Wardani Exsa Hadibrata Hasyim Adhafizh Sofyan Helmi Ismunandar Hendri Busman Iswandi Darwis Malik Ahza Nugroho Muhammad Fauzan Iqbal Muhammad Iqbal Ramadhan Mukhlis Imanto Nabeel Muhammad Naila Fathiya Isnanto Nashwa Amirul Haq Azzuhri Oktadoni Saputra Oktafany Oktafany Rafi Gutra Aslam Rasha Andhika Satria Reni Indriyani Risal Wintoko Rodiani Susianti Susianti Sutarto Sutarto T.A Larasati Waluyo Rudiyanto