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All Journal Medula JURNAL PENELITIAN PERAWAT PROFESIONAL Journal of Language and Health Indonesian Journal of Nursing and Health Sciences (IJNHS) Jurnal Ilmiah STIKES Yarsi Mataram
Exsa Hadibrata
universitas lampung
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Pengaruh Jus Tomat (Solanum lycopersicum) terhadap Tebal Epitel Seminiferus Tikus Putih Galur Sprague dawley yang Diinduksi Gentamisin Fahmi Ikhtiar; Exsa Hadibrata
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.382

Abstract

Aminoglycosides including gentamicin have been used successfully for decades in the treatment of gram-negative bacterial infections. However, gentamicin produces testicular toxicity, resulting in limited therapeutic doses. Lycopene, one of the antioxidants in tomatoes, has singlet-oxygen and free radical scavenging capacity. Moreover, lycopene serves as a promising intervention for testicular toxicity associated with oxidative stress. Researchers wanted to see the effect of tomato juice on the seminiferous tubules of white rats. This type of research is experimental research with post test only control group design. The rats used were 29 male white rats (Rattus novergicus) which were divided into 5 groups, namely the negative control group as normal control. The positive control group was given gentamicin 20 mg/kgBW. Treatment groups 1, 2, and 3 were the treatment groups with gentamicin 20 mg/kgBW and tomato juice 25%, 50%, and 100%. Gentamicin was given for 10 days and tomato juice was given for 24 days. Data analysis was carried out using the One Way Annova method and continued with Post Hoc. After statistical testing, there was a significant effect of giving tomato juice on seminiferous epithelial thickness induced by gentamicin in white rats of the Sprague Dawley strain (p<0.05).
Efikasi dan Komplikasi Supine Percutaneous Nephrolithotomy (PCNL) dengan Panduan Kombinasi Ultrasonografi (USG) dan Fluoroskopi Exsa Hadibrata; Mars Dwi Tjahyo; Suharmanto Suharmanto
Jurnal Penelitian Perawat Profesional Vol 5 No 1 (2023): Februari 2023, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v5i1.1287

Abstract

Operasi minimal invasif untuk tatalaksana batu ginjal diantaranya, Electro Shock Wave Lithotripsy (ESWL), ureteroskopi, bedah laparoskopik dan Percutaneous Nephrolithotripsy (PCNL) yang telah mengubah manajemen batu ginjal. Penelitian ini dilakukan untuk mengetahui delta Hb, kebutuhan tranfusi, durasi operasi, durasi fluoroskopi, stone free rate, lama perawatan dan komplikasi tindakan supine PCNL dengan teknik kombinasi USG dan flouroskopi pada pasien batu ginjal di Rumah Sakit Umum Daerah Abdul Moeloek tahun 2020. Penelitian ini merupakan studi retrospektif menggunakan rekam medik dan digunakan teknik total sampling pada 31 orang. Data dikumpulkan dari rekam medik dan dianalisis menggunakan analisis univariat berupa distribusi frekuensi. Hasil penelitian mendapatkan stone burden 20-50 mm sebanyak 23 sampel, dan 50 mm sebanyak 8 sampel. Pasca tindakan supine PCNL stone free rate sebesar 84%, dengan rerata durasi operasi 104 menit dan rerata durasi flouroskopi 12,4 menit. Sebanyak 8 sampel membutuhkan tranfusi darah. Komplikasi terbanyak yang timbul pasca tindakan berdasarkan modified clavien grading skor adalah grade 1 dan grade 2. Tindakan supine PCNL merupakan tindakan yang dapat dijadikan pilihan sebagai tataklasana batu ginjal > 20 mm dengan stone free rate cukup baik dan komplikasi yang minimal.
Ewing Sarkoma: Ulasan Singkat Keganasan: Indonesia Rafi Gutra Aslam; Helmi Ismunandar; Risal Wintoko; Exsa Hadibrata; Anisa Nuraisa Jausal
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.336

Abstract

A malignancy that identified first by James Ewing in 1921. Ewing sarcoma is a malignancy of the bones caused by abnormal activity of progenitor cell mesenchymal occurs by a genetic factor where the patient had a combination of translocation chromosome non-random in t(11; 22) (q24;q12) or t(21; 22) (q22; q12). The patient will have pathognomonic findings of periosteal reaction similar to "Onion skin", lesions like “Moth-eaten”, and “Codman’s Triangle” in radiology findings. Second highest malignancy bone prevalent worldwide after osteosarcoma. This malignancy occurs commonly in the male gender, incidence peaked in the approximately first decade in life with a prognosis range of about 5 years more or less. The malignancy occurs in the metaphysis-diaphysis part of the bone that has a variety of prognoses based on stage, metastasis, and therapy. Literature Review method is used in this article writing by article, journal, and book that review shortly about Ewing sarcoma from multi-aspect of etiology, epidemiology, pathogenesis and pathophysiology, clinical manifestations, treatment, staging, prognosis, complication, and education as the last topic. Prognosis of Ewing Sarcoma patient will be better if given multimodal therapy including chemotherapy, radiotherapy, and operation that adjusted with the condition in every patient. Nevertheless, further research is needed about best treatment in goals to extend patient survivability and enhance prognoses approximately in 3 years.
Strategi Pencegahan Bullying pada Remaja di Sekolah Suharmanto Suharmanto; Waluyo Rudiyanto; Exsa Hadibrata
Journal of Language and Health Vol. 6 No. 3 (2025): Journal of Language and Health: September 2025
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jlh.v6i3.620

Abstract

Penelitian di Indonesia tercatat 67,9% remaja SLTA dan 66,1% remaja SLTP mendapatkan perilaku bullying. Pencegahan bullying dapat dilakukan melalui peningkatan sosialisasi dan edukasi, dukungan sosial dan membuat kebijakan di sekolah terkait pencegahan bullying. Tujuan penelitian ini adalah menggambarkan strategi pencegahan bullying pada remaja di sekolah. Penelitian ini merupakan penelitian kualitatif dengan pendekatan fenomenologi, yang dilakukan di SMK Bintang Nusantara Marga Agung Lampung Selatan pada bulan April-September 2025. Subjek penelitian ini adalah kepala sekolah, guru BK dan siswa/i di SMK Bintang Nusantara Marga Agung Lampung Selatan sebanyak 12 orang, menggunakan purposive sampling. Teknik pengumpulan data menggunakan teknik wawancara, observasi dan dokumentasi. Teknik analisis data yang digunakan pada penelitian ini menggunakan model analisis Miles dan Huberman, yaitu reduksi data, penyajian data, dan penarikan kesimpulan. Teknik keabsahan data dalam penelitian kualitatif meliputi uji credibility, transferability, dependability, dan confirmability. Analisis menggunakan analisis tematik. Pencegahan bullying dan kekerasan pada anak di lingkungan sekolah merupakan tanggung jawab bersama seluruh pihak terkait, termasuk pemerintah, sekolah, orangtua, dan masyarakat.
Pengaruh Peer Education Terhadap Perilaku Breast Self Examination (BSE) pada Wanita Usia Subur suharmanto suharmanto; Exsa Hadibrata
Jurnal Ilmiah STIKES Yarsi Mataram Vol. 15 No. 1 (2025): Jurnal Ilmiah STIKES Yarsi Mataram
Publisher : Institut Kesehatan YARSI Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/jisym.v15i1.431

Abstract

The incidence of breast cancer in Indonesia is increasing which can be detected as a preventive effort with breast self-examination. The purpose of this study was to analyze the effect of peer education on breast self-examination behavior. This study used a pre-experimental method, involving 87 people each in the intervention and control groups. Data collection tools used questionnaires and checklist sheets. The results of the study showed that most respondents experienced an increase in knowledge, attitudes, and skills in conducting BSE, so it is hoped that the community can increase their knowledge by reading books, attending seminars, counseling, and training related to breast cancer prevention. ABSTRAK Insidensi kanker payudara di Indonesia meningkat yang dapat dideteksi sebagai upaya pencegahan dengan breast  self  examination. Tujuan penelitian ini adalah menganalisis pengaruh peer education terhadap perilaku breast  self  examination. Penelitian ini  menggunakan metode pra- eksperimen, melibatkan masing-masing 87 orang kelompok intervensi dan kontrol. Alat pengumpul data menggunakan kuesioner dan lembar ceklist. Hasil penelitian menunjukkan bahwa sebagian besar responden mengalami peningkatan pengetahuan, sikap dan keterampilan dalam melakukan BSE, sehingga diharapkan kepada masyarakat agar dapat meningkatkan pengetahuannya dengan cara membaca buku, mengikuti seminar, penyuluhan dan pelatihan terkait pencegahan kanker payudara
Health Belief Model Application Related to Safe Work Behavior Against Poisoning Prevention in Farmers Using Pesticides suharmanto suharmanto; Exsa Hadibrata; Risal Wintoko
Jurnal Ilmiah STIKES Yarsi Mataram Vol. 15 No. 1 (2025): Jurnal Ilmiah STIKES Yarsi Mataram
Publisher : Institut Kesehatan YARSI Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/jisym.v15i1.432

Abstract

The World Health Organization estimates that pesticide poisoning occurs yearly in the world and Indonesia. This study aimed to analyze the influence of the Health Belief Model related to safe work behavior on the prevention of poisoning in farmers who use pesticides. This type of research is observational analytic, with a sample of 400 people. The data collection tool used a questionnaire. Data processing includes coding, tabulating, and cleaning. Data analysis used univariate (percentage) and bivariate using the Chi-Square test. The study found a relationship between the dimensions of the Health Belief Model related to safe work behavior on preventing poisoning in farmers who use pesticides. The conclusion of this study is that there is a relationship between the dimensions of the Health Belief Model and the prevention of poisoning in farmers who use pesticides, so it is hoped that the community can increase their knowledge by reading books, attending seminars, counseling and training related to the prevention of poisoning due to the use of pesticides. ABSTRAK World Health Organization memperkirakan setiap tahun terjadi keracunan pestisida di dunia dan Indonesia. Tujuan penelitian ini adalah menganalisis pengaruh Health Belief Model terkait perilaku kerja aman terhadap pencegahan keracunan pada petani pengguna pestisida. Jenis penelitian ini observasional analitik, dengan sampel 400 orang. Alat pengumpul data menggunakan kuesioner. Pengolahan data meliputi coding, tabulating dan cleaning. Analisis data menggunakan univariat (persentase) dan bivariat menggunakan uji Chi-Square. Penelitian mendapatkan adanya hubungan dimensi Health Belief Model terkait perilaku kerja aman terhadap pencegahan keracunan pada petani pengguna pestisida. Simpulan penelitian ini adalah ada hubungan antara dimensi Health Belief Model dengan pencegahan keracunan pada petani pengguna pestisida, sehingga diharapkan kepada masyarakat agar dapat meningkatkan pengetahuannya dengan cara membaca buku, mengikuti seminar, penyuluhan dan pelatihan terkait pencegahan keracunan akibat penggunaan pestisida.
Analisis Fungsi Ereksi pada Tikus Jantan Model Hiperglikemia yang Diinduksi Aloksan Setelah Pemberian Ekstrak Lada Hitam (Piper Nigrum L.) Exsa Hadibrata; Suharmanto Suharmanto
Indonesian Journal of Nursing and Health Sciences Vol 6 No 2 (2025): Indonesian Journal of Nursing and Health Sciences: October 2025
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijnhs.v6i2.7374

Abstract

Disfungsi ereksi pada pria hiperglikemia sering kali disebabkan oleh perubahan mikrovaskuler, neuropati, dan disfungsi endotel. Kondisi ini dapat diatasi dengan pemberian ekstrak lada hitam (Piper nigrum L.). Tujuan penelitian ini untuk menganalisis fungsi ereksi pada tikus jantan model hiperglikemia yang diinduksi aloksan setelah pemberian ekstrak lada hitam (Piper nigrum L.). Penelitian ini merupakan penelitian eksperimen, yang dilakukan di Laboratorium Biokimia dan Biomolekuler Fakultas Kedokteran Universitas Lampung bulan Juli-Agustus 2025. Penelitian ini menggunakan tikus putih jantan Rattus norvegicus galur Sprague Dawley sebagai subjek uji, sebanyak 6 ekor dan 5 kelompok (30 ekor). Perlakuan pemberian ekstrak diberikan setiap hari selama 8 hari pada seluruh kelompok. Penentuan dosis ekstrak lada hitam sebesar 122,5mg/KgBB dan 245mg/KgBB selama 8 hari. Fungsi ereksi hewan percobaan dinilai melalui hasil Total Penile Reflex (TPR). Uji statistik yang digunakan adalah Oneway ANOVA. Pemberian ekstrak lada hitam pada tikus hiperglikemia terbukti dapat memperbaiki fungsi ereksi tikus jantan (p<0,001).
Co-Authors Anisa Nuraisa Jausal Fahmi Ikhtiar Helmi Ismunandar Mars Dwi Tjahyo Rafi Gutra Aslam Risal Wintoko Suharmanto Suharmanto Waluyo Rudiyanto