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Development of the Obesity Nutraceutical from Raja and Kepok Banana Peels Kezia Elian Devina; Dono Indarto; Tri Nugraha Susilawati
Proceedings of the International Conference on Nursing and Health Sciences Vol 4 No 1 (2023): January-June 2023
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/picnhs.v4i1.1817

Patients with obesity often fail to control their body weight through diet and physical activity, while the existing anti-obesity drugs have some side effects for long-term use. Banana is Indonesia's tropical fruits with the highest production, and the banana peel has become soil waste. This study aimed to analyze nutrients and active compounds of methanol extracts of raja and kepok banana peels (ERP and EKP respectively). Macro and micro-nutrient compositions of the ERP and EKP were determined using the proximate analysis, while Thin Layer Chromatography (TLC) was used to detect the ERP and EKP active compounds. The ERP contained 0.11% crude fibers, 4.44% fat, and 58.08% carbohydrates, different from the EKP (4.25% protein, 20.95% water, and 14.45% minerals). By contrast, both the ERP and EKP contained flavonoids, phenols, tannins, alkaloids, and saponins. In conclusion, ERP is potentially developed as a nutraceutical for obesity treatment in the future. Further study is needed to measure specific fat levels and to analyze specific active compounds in the ERP which can modulate gene expression and interact with protein targets in lipid metabolism.

The effects of raja banana (Musa acuminata) peel extract on body weight, body mass index, body fat percentage, and visceral fat mass in male rats with obesity Devina, Kezia Elian; Indarto, Dono; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 12 ISSUE 2, 2024
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2024.12(2).115-125

Background: Obesity is a risk factor for metabolic syndrome which can increase mortality. Obese sufferers often fail to lose body weight (BW) through non-pharmacological therapy. Obesity synthetic drugs can cause side effects, so natural ingredients are needed as alternative therapies.Objectives: This study aims to determine the effect of raja banana peel extract (RBPE) on BW, body mass index (BMI), body fat percentage (BFP), and visceral fat mass in obese male rats.Methods: The research subjects were 30 male Wistar rats weighing 125-200 g, aged eight weeks. Obesity was induced by being given high-fat high fructose (HFHFr) feed for 28 days. Rats were randomized and divided into five groups: the negative control group (C-) was given standard feed and distilled water, the positive control (C+) was given standard feed and orlistat, treatment 1 (T1), treatment 2 (T2), and treatment 3 (T3). Which were given standard feed and RBPE doses of 200 mg/kgBW/day, 400 mg/kgBW/day, and 800 mg/kgBW/day. Data before and after the induction of obesity were analyzed using paired t-tests. BW, BMI, and visceral fat mass were analyzed using the One-Way Analysis of Variance (ANOVA) and Repeated Measure ANOVA tests. BFP was analyzed using the Kruskal-Wallis test and the Friedman test.Results: RBPE can significantly reduce BW (p=0.026), BMI (p<0.001), and BFP (p<0.001). However, all groups had no significant difference in visceral fat mass (p=0.187). T3 was the group with the lowest average BW, BMI, BFP, and visceral fat mass although the highest weight loss during the intervention period occurred in C+.Conclusions: RBPE has the potential as an alternative therapy for obesity because it can reduce BW, BMI, and BFP. Future studies can investigate the effect of RBPE on other obesity parameters such as lipid profiles.

The effects of raja banana (Musa acuminata) peel extract on body weight, body mass index, body fat percentage, and visceral fat mass in male rats with obesity Devina, Kezia Elian; Indarto, Dono; Susilawati, Tri Nugraha; Wiboworini, Budiyanti
Jurnal Gizi dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics) VOLUME 12 ISSUE 2, 2024
Publisher : Alma Ata University Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21927/ijnd.2024.12(2).115-125

Background: Obesity is a risk factor for metabolic syndrome which can increase mortality. Obese sufferers often fail to lose body weight (BW) through non-pharmacological therapy. Obesity synthetic drugs can cause side effects, so natural ingredients are needed as alternative therapies.Objectives: This study aims to determine the effect of raja banana peel extract (RBPE) on BW, body mass index (BMI), body fat percentage (BFP), and visceral fat mass in obese male rats.Methods: The research subjects were 30 male Wistar rats weighing 125-200 g, aged eight weeks. Obesity was induced by being given high-fat high fructose (HFHFr) feed for 28 days. Rats were randomized and divided into five groups: the negative control group (C-) was given standard feed and distilled water, the positive control (C+) was given standard feed and orlistat, treatment 1 (T1), treatment 2 (T2), and treatment 3 (T3). Which were given standard feed and RBPE doses of 200 mg/kgBW/day, 400 mg/kgBW/day, and 800 mg/kgBW/day. Data before and after the induction of obesity were analyzed using paired t-tests. BW, BMI, and visceral fat mass were analyzed using the One-Way Analysis of Variance (ANOVA) and Repeated Measure ANOVA tests. BFP was analyzed using the Kruskal-Wallis test and the Friedman test.Results: RBPE can significantly reduce BW (p=0.026), BMI (p<0.001), and BFP (p<0.001). However, all groups had no significant difference in visceral fat mass (p=0.187). T3 was the group with the lowest average BW, BMI, BFP, and visceral fat mass although the highest weight loss during the intervention period occurred in C+.Conclusions: RBPE has the potential as an alternative therapy for obesity because it can reduce BW, BMI, and BFP. Future studies can investigate the effect of RBPE on other obesity parameters such as lipid profiles.

Association of Sugar-Sweetened Beverage Intake with Waist Circumference and Overweight Among Kusuma Husada University Students Devina, Kezia Elian; Lestari, Puji; Vierdiana, Dyah
Jurnal Ilmu Gizi dan Dietetik Vol 5 No 2 (2026)
Publisher : Departemen Gizi Masyarakat, Fakultas Ekologi Manusia, IPB dan PERGIZI PANGAN Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jigd.2026.5.2.517-526

Students are one of the groups vulnerable to nutritional problems, including overweight. The increasing availability of sugar-sweetened beverages (SSBs) in shops and cafés has encouraged their consumption among students. SSBs contain added sugars and are generally high in calories, which may contribute to increased body fat, body weight, and waist circumference, thereby increasing the risk of overweight. This study aimed to determine the association between SSB consumption, waist circumference, and overweight among students of the Faculty of Health Sciences, Kusuma Husada University, Surakarta. This analytical observational study employed a cross-sectional design. Data were collected through anthropometric measurements of body weight, height, and waist circumference, as well as a respondent characteristics questionnaire. A Food Frequency Questionnaire (FFQ) was used to assess SSB consumption during the previous month. Data were analyzed using the Chi-square test. The results showed that most participants rarely consumed SSBs, had normal waist circumference, and were not overweight. No significant association was found between SSB consumption and waist circumference (p=0.683) or overweight (p=0.523). In conclusion, SSB consumption was not significantly associated with waist circumference or overweight among students of the Faculty of Health Sciences, Kusuma Husada University, Surakarta.

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