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MODIFIED FEEDING BOTTLE FOR INFANT WITH CLEFT LIP AND PALATE AT THE PERIPHERAL AREA: A CASE REPORT Mardiyantoro, Fredy; Hapsari, Diwya Nugrahini; Milla, Lalita El
Jurnal Ilmiah dan Teknologi Kedokteran Gigi Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/jitekgi.v15i1.695

Introduction:A newborn can suck at breast and latch well to get breast milk, but infants born with cleft lip and palate have difficulties to press the nipple by their tongues towards palatal direction. Case:A 10-day-old female infant came with complaint of not being able to breastfeed from a normal bottle and accordingly need to use spoon for milk feeding. She was planned to perform first step operation at 3 months with minimum 10 pounds of body weight. For nutrient intake, nasogastric tube had been placed on the patient. Case management :At the first visit, impression procedure was performed using red wax material that previously warmed thus it can be shaped according to the defect on infant’s palate. Subsequently, feeding obturator was fabricated using the resulting cast. Fabrication of feeding obturator used putty impression material combined with feeding bottle nipple. Thereafter, the modified feeding bottle was tried in the patient’s mouth. Conclusion:the use of putty material combined with feeding bottle nipple in infants with cleft palate may function as obturator. Furthermore, correction using the one of the modified feeding bottle can be carried out every 1-2 weeks until surgical repair of the cleft palate is performed.Keywords: cleft palate, feeding bottle, putty material, nutrition

PENGARUH LENDIR BEKICOT (Achatina fulica) TERHADAP JUMLAH FIBROBLAS PADA SOKET Mardiyantoro, Fredy; Zainal Abidin, Zefry; Swastirani, Astika; Dibya, Handaru
E-Prodenta Journal of Dentistry Vol 4, No 2 (2020)
Publisher : Fakultas Kedokteran Gigi UB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.eprodenta.2020.004.02.1

Latar belakang : Penyembuhan luka adalah proses dinamis yang menghasilkan serangkaian aktivitas termasuk peradangan, proliferasi, dan migrasi sel-sel fibroblast ke daerah luka. Fibroblas sangat penting dalam mendukung penyembuhan luka normal, dari fase akhir inflamasi hingga fase akhir epitelisasi pada jaringan yang mengalami jejas. Tujuan : Penelitian ini mengamati pengaruh lendir bekicot (Achatina fulica) dalam mempercepat proses penyembuhan melalui proliferasi fibroblas di soket paska pencabutan gigi. Metode : Tikus wistar (Rattus novergicus) dibagi menjadi dua kelompok, dan gigi insisivus pertama rahang bawah kiri mereka dicabut. Soket bekas pencabutan diberikan lendir bekicot pada kelompok perlakuan dan kelompok kontrol tidak diberikan lendir bekicot. Pada hari ke 3, 5 dan 7, tikus dilakukan eutanasia dan sampel jaringan diolah untuk analisis histologi. Hasil : Uji statistik penelitian menunjukkan bahwa lendir bekicot (Achatina fulica) secara signifikan meningkatkan jumlah sel fibroblas pada kelompok perlakuan dibandingkan dengan kelompok kontrol (p<0,05). Kesimpulan : Dari penelitian ini dapat disimpulkan bahwa lendir siput (Achatina fulica) mempunyai potensi yang cukup baik dalam merangsang proses penyembuhan luka setelah pencabutan gigi.

EFEK TOOTHGRAFT TERHADAP JUMLAH OSTEOBLAS SOKET TIKUS PASCA PENCABUTAN Kumala, Ega Chandra; Mardiyantoro, Fredy; Salaras, Pinti Mei Sarnia Wahyu
E-Prodenta Journal of Dentistry Vol 5, No 2 (2021)
Publisher : Fakultas Kedokteran Gigi UB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.eprodenta.2021.005.02.7

Latar Belakang: Bovine graft sebagai bahan pengganti tulang terkadang menimbulkan reaksi penolakan dari tubuh. Bahan tooth graft dari gigi yang diekstraksi memiliki kemiripan subtansi dengan tulang. Tujuan: Menganalisis efek implantasi tooth graft terhadap osteoblas dibandingkan dengan bovine graft pada soket alveolar tikus Wistar pasca pencabutan. Metode: Desain penelitian ini Â adalah eksperimental laboratoris menggunakan 24 sampel yang dibagi menjadi 4 kelompok. Keempat kelompok dilakukan pencabutan gigi insisif pertama mandibula, pada 2 kelompok diaplikasikan tooth graft dan 2 kelompok diaplikasikan bovine graft selama 14 hari dan 30 hari. Jumlah sel osteoblas dihitung secara manual. Hasil: analisis data dengan uji statistik T test menunjukkan nilai yang tidak signifikan (p< 0,05) pada jumlah sel osteoblas pasca aplikasi tooth graft dan bovine graft pada hari ke-14 dan hari ke-30. Kesimpulan: Bahan tooth graftÂ Â dapat mempengaruhi jumlah sel osteoblas sama baiknya dengan bovine graft untuk perawatan pada tikus wistar pasca ekstraksi gigi.

Evaluasi Jumlah Limfosit Pasca Aplikasi Lendir Bekicot (Achatina fulica) pada Soket Tikus Wistar (Rattus norvegicus) Riyani, Nadya Jeihan; Pasaribu, Robisnson; Mardiyantoro, Fredy
Sinnun Maxillofacial Journal Vol. 3 No. 01 (2021): April 2021
Publisher : Fakultas Kedokteran Gigi Universitas Muslim Indonesia

Pendahuluan: Peradangan merupakan respon dasar terhadap adanya kerusakan jaringan atau luka pasca pencabutan gigi yang kemudian dilanjutkan dengan proses penyembuhan. Lendir bekicot dari spesies Achatina fulica diketahui memiliki kemampuan sebagai alternatif obat yang mempercepat proses penyembuhan luka. Tujuan Penelitian: penelitian ini bertujuan menguji pengaruh lendir bekicot (Achatina fulica) terhadap jumlah limfosit pada proses penyembuhan luka soket gigi pasca pencabutan gigi tikus wistar (Rattus norvegicus). Bahan dan Metode: Penelitian ini menggunakan bahan utama berupa lendir bekicotÂ yang diaplikasikan pada soket gigi tikus. Sampel dipilih menggunakan teknik Simple Random Sampling kemudian dibagi ke dalam dua kelompok, yaitu kelompok kontrol (K) dan perlakuan (P). Variabel yang diteliti pada penelitian ini adalah jumlah limfosit pada hari ketiga, kelima, dan ketujuh proses penyembuhan luka soket gigi tikus wistar yang diukur dari sediaan HPA dengan pengecatan Hematoxylin-Eosin. Hasil: Hasil penelitian menunjukan adanya perbedaan jumlah limfosit pada hari ketiga, kelima, dan ketujuh baik pada kelompok kontrol (K) maupun perlakuan (P). Dengan jumlah rerata limfosit pada kelompok kontrol adalah 5,48 ; 4,60 ; 64,48. Sedangkan hasil rerata limfosit kelompok perlakuan adalah : 11,6; 16,52; 10,80. Kesimpulan : penelitian ini menunjukkan bahwa lendir bekicot (Achatina fulica) berpengaruh pada jumlah limfosit pada proses penyembuhan luka soket gigi tikus wistar (Rattus norvegicus).

Potential Effect of Djambal Catfish (Pangasius djambal) Gelatin as Biomaterial Product on Healing Socket after Tooth Extraction in Rats Fredy Mardiyantoro; Nenny Prasetyaningrum; Miftakhul Cahyati; Zefry Zainal Abidin; Norifumi Nakamura
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i2.14728

Purpose: Adequate wound healing after a tooth extraction is significant because the oral cavity has amasticatory function and plays a role in nutrient intake. Various scientific studies have been conducted tofind the ideal biomaterial to support wound healing. This study aims to determine the wound healing activityusing Djambal Catfish (Pangasius djambal) gelatin after tooth extraction.Method: Gelatin was obtained from Djambal Catfish (Pangasius djambal). The sample was selected byrandom sampling, divided into 6 groups, namely the control group on the 3rd day (n=6), the control groupon the 5th day (n=6), the control group on the 7th day (n=6), the treatment group on the 3rd day (n=6), thetreatment group on the 5th day (n=6), and the treatment on the 7th day (n=6). Wound healing was examinedby evaluating wound healing marker such as macrophages, fibroblasts, epithelialization, angiogenesis, andcollagen. Data were processed using statistical analysis.Results: The treatments had a positive result in wound healing as compared with the control groups.Histological assessment showed a remarkable sign of an increased number of macrophage, fibroblast,epithelialization, and collagen deposition.Conclusion: Gelatin derived from Djambal Catfish (Pangasius djambal) can accelerate the wound healingprocess thus could be a component therapeutic potential product that may be beneficial in wound healing inthe future.

MODIFIED FEEDING BOTTLE FOR INFANT WITH CLEFT LIP AND PALATE AT THE PERIPHERAL AREA: A CASE REPORT Fredy Mardiyantoro; Diwya Nugrahini Hapsari; Lalita El Milla
Jurnal Ilmiah dan Teknologi Kedokteran Gigi Vol 15, No 1 (2019)
Publisher : Fakultas Kedokteran Gigi Universitas Prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/jitekgi.v15i1.695

Introduction:A newborn can suck at breast and latch well to get breast milk, but infants born with cleft lip and palate have difficulties to press the nipple by their tongues towards palatal direction.Case:A 10-day-old female infant came with complaint of not being able to breastfeed from a normal bottle and accordingly need to use spoon for milk feeding. She was planned to perform first step operation at 3 months with minimum 10 pounds of body weight. For nutrient intake, nasogastric tube had been placed on the patient.Case management :At the first visit, impression procedure was performed using red wax material that previously warmed thus it can be shaped according to the defect on infants palate. Subsequently, feeding obturator was fabricated using the resulting cast. Fabrication of feeding obturator used putty impression material combined with feeding bottle nipple. Thereafter, the modified feeding bottle was tried in the patients mouth.Conclusion:the use of putty material combined with feeding bottle nipple in infants with cleft palate may function as obturator. Furthermore, correction using the one of the modified feeding bottle can be carried out every 1-2 weeks until surgical repair of the cleft palate is performed.Keywords:cleft palate, feeding bottle, putty material, nutrition

Histopathological characteristics of dental socket healing on collagen density following use of pangas catfish (Pangasius djambal) gelatin Fredy Mardiyantoro; Nenny Prasetyaningrum; Hani Tri Rahmastuti
Majalah Kedokteran Gigi Indonesia Vol 5, No 3 (2019): December
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/majkedgiind.39830

Tooth extraction is a common treatment in dental practice. However, complications such as bleeding or dry socket may occur during healing process. Pangas catfish (Pangasius djambal) gelatin contains glutamine which could increase the proliferation of fibroblast, accordingly collagen synthesis increases. The study aimed to demonstrate collagen density after the application of pangas catfish gelatin on post-tooth extraction wound of albino rats (Rattus norvegicus). This wasan experimental study with randomized posttest-only control group design which involved male Wistar strain albino rats. The rats were selected using a random sampling method and divided into four groups, namely day-3 control group (n=7),day-7 control group (n=7), day-3 treatment group (n=7) and day-7 treatment group (n=7). Pangas catfish gelatin was administered into the socket once after extraction. The variable measured in the study was collagen density, determinedby collagen scoring of hematoxylin eosin–stained histopathological preparations. Collagen formation were determined according to the assessment criteria of collagen distribution and density. Data analysis showed there was a significantdifference of collagen synthesis between the control and treatment groups according to Kruskal-Wallis test of which the result of control group day-3 was 1.13 ± 0.34, control group day-7 was 1.76 ± 0.67, treatment group day-3 was 1.66 ±0.47 and treatment group day-7 was 2.93 ± 0.25. In addition, the day-7 treatment group showed the highest collagen scoring values as compared to the control groups according to the Mann-Whitney test (p<0.05). In conclusion, pangascatfish gelatin increased collagen density during dental socket healing process after tooth extraction in albino rats.

ONE-PIECE DENTAL IMPLANT UNTUK REHABILITASI RUANG KANINUS YANG SEMPIT Fredy Mardiyantoro; Ariyati Retno Pratiwi
ODONTO : Dental Journal Vol 4, No 1 (2017): July 2017
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.4.1.61-66

Background: Tooth loss has serious functional, esthetic disabilities, and compromising the patients’ quality of life. Dental implant treatment has become increasingly common for the management tooth loss. Different clinical situations, such as narrow edentulous space, are often encountered in which modifications have to be considered in order to achieve successful rehabilitation. One piece dental implan provided a solution for rehabilitation of narrow edentulous space. The purpose of this paper is to report a rehabilitation management of narrow edentulous space. Case Management: A 22-year-old woman had an upper right canine #13 malposition so there was a narrow space between upper right lateral insisiv #12 and upper right first premolar #14. The spacing between upper right lateral insisivus #12 and upper right first premolar #14 was found to be about 5 mm. Radiograph was assessed for type of bone and for the presence of any pathology. A patient given an initial dental treatment such as scalling root planning and extraction of caninus #13. Following the clinical evaluation, the procedure and complication of implant therapy were explained and consent taken for proposed treatment. One piece dental implant site was anesthetized. Flaps on the buccal aspect were raised. One Piece dental implant inserted using dental implant kit. On completion of treatment, the patient’s esthetics and funcions improved. Conclusion: This study observed that one piece dental implants are suitable for rehabilitation of narrow edentulous space

PENGARUH GELATIN IKAN PATIN (PANGASIUS DJAMBAL) TERHADAP JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI TIKUS PUTIH (RATTUS NORVEGICUS) Fredy Mardiyantoro; Fidya Fidya; Dena Savira Andriani
ODONTO : Dental Journal Vol 6: Special Issue 1. April 2019
Publisher : Faculty of Dentistry, Universitas Islam Sultan Agung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/odj.6.1.1-5

Background: Gelatin has been used as a hemostatic agent to stop bleeding and it can be absorbed by human body within 6 hours. The patin fish (Pangasius djambal) gelatin has a high amount of amino acid, especially glutamine which has an important role in increasing the proliferation of fibroblast in wounds. The purpose of this study was to determine the effect of patin fish gelatin to the number of fibroblast in wound after tooth extraction.Method: Rat’s tooth extraction is done on the lower left incisive tooth. Thirty white rats were divided into two groups randomly with 3 time series. Control group was the rats without given of patin fish gelatin and treatment group was the rats given 1cc of patin fish gelatin with pipette. Socket taken for histologically processed by Hematoxylin Eosin staining.Result: It showed there were significant differences in the number of fibroblasts between groups. The Post Hoc Tukey test result showed there was a significant difference between the control group and the treatment group.Conclusion: Patin fish gelatin has effect increasing the number of fibroblast inwound after white rat’s (Rattus norvegicus) tooth extraction

EFEK TOOTHGRAFT TERHADAP JUMLAH OSTEOBLAS SOKET TIKUS PASCA PENCABUTAN Ega Chandra Kumala; Fredy Mardiyantoro; Pinti Mei Sarnia Wahyu Salaras
E-Prodenta Journal of Dentistry Vol 5 No 2 (2021)
Publisher : Fakultas Kedokteran Gigi UB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.eprodenta.2021.005.02.7

Latar Belakang: Bovine graft sebagai bahan pengganti tulang terkadang menimbulkan reaksi penolakan dari tubuh. Bahan tooth graft dari gigi yang diekstraksi memiliki kemiripan subtansi dengan tulang. Tujuan: Menganalisis efek implantasi tooth graft terhadap osteoblas dibandingkan dengan bovine graft pada soket alveolar tikus Wistar pasca pencabutan. Metode: Desain penelitian ini Â adalah eksperimental laboratoris menggunakan 24 sampel yang dibagi menjadi 4 kelompok. Keempat kelompok dilakukan pencabutan gigi insisif pertama mandibula, pada 2 kelompok diaplikasikan tooth graft dan 2 kelompok diaplikasikan bovine graft selama 14 hari dan 30 hari. Jumlah sel osteoblas dihitung secara manual. Hasil: analisis data dengan uji statistik T test menunjukkan nilai yang tidak signifikan (p< 0,05) pada jumlah sel osteoblas pasca aplikasi tooth graft dan bovine graft pada hari ke-14 dan hari ke-30. Kesimpulan: Bahan tooth graftÂ Â dapat mempengaruhi jumlah sel osteoblas sama baiknya dengan bovine graft untuk perawatan pada tikus wistar pasca ekstraksi gigi.

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