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PERBANDINGAN MUTU BERDASARKAN PROFIL DISOLUSI TABLET GLIBENKLAMID PATEN DAN GENERIK YANG BEREDAR DI MAKASSAR Mursyid, A. Mumtihanah; Hasyim, Nursiah; Jauhari, Evy Fajrianti
Jurnal Ilmiah As-Syifaa Vol 8, No 1 (2016): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (121.561 KB) | DOI: 10.33096/jifa.v8i1.158

Abstract

A research of dissolution testing of patent and generic glibenclamide tablet have been done. The purpose of this research is to determine quality of patent and generic glibenclamide tablet that circulated in Makassar. Glibenclamide tablets patent and generic dissolution have been tested with paddle methode in 500 ml posfat buffer pH 7,4, medium was accomplished at 37 oC±0,5 the speed of 75 rpm. Aliquot retaken as much 5 ml is done at time intervas of 10, 20, 30, 45, and 60 mnutes and then, the concentrations is confiruxed by spektrofotometer UV-VIS at the 299 nm wavelength. Based on the dissolution experiment result, the acquired glibenclamide percentage that was dissolute from glibenclamide tablets generic A = 85,686 %, generic B = 81,336 % and paten = 126,665 % have fulfill the dissolution the condition according to British Pharmacphea 2008. That is the dissolute is not less than 75 % within 45 minutes. And the average of Dissolution value efficiency (ED) rate each glibenclamide tablet paten = 115,29 %, generic B = 72,409 % and generic A = 77,352 %.
FORMULASI DAN EVALUASI SALEP EKSTRAK DAUN GULMA SIAM (Chromolaena odorata L.) DENGAN VARIASI BASIS SALEP Hasrawati, A.; Famir, Yasir; Aztriana, Aztriana; Mursyid, A. Mumtihanah
Jurnal Ilmiah As-Syifaa Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.872 KB) | DOI: 10.33096/jifa.v11i1.514

Abstract

Siam weed leaves are one of the plants that function as wound medicine. This study aims to produce a stable ointment dosage form. Siamese weed leaf extract is formulated in the form of ointment with a variety of bases consisting of a hydrocarbon base, absorption, water soluble and emulsion. Evaluation of physical stability includes organoleptic testing, homogeneity, pH, dispersion, viscosity and flow properties carried out before and after forced conditions. Forced conditions were carried out with stock storage for 10 cycles at 50 and 350. The results of the analysis showed that the viscosity of the preparations in all formulas changed after storage at 50 and 350 for 5 days. However, the statistical results show that all formulas did not experience significant changes between before and after the stress condition treatment.
ANALISIS PENGARUH TEMPAT PENYIMPANAN TERHADAP BESARNYA KANDUNGAN LOGAM Pb DAN Zn DALAM DAGING KORNET HABIS PAKAI KEMASAN KALENG Syakri, Syamsuri; Mursyid, A. Mumtihanah
Jurnal Ilmiah As-Syifaa Vol 5, No 1 (2013): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (113.147 KB) | DOI: 10.33096/jifa.v5i1.66

Abstract

This research was conducted with the aim to investigate the influence of storage on the size of the metal content of Pb and Zn to quality consumable products corned beef cans obtained from a grocery store or supermarket, and to determine the ratio between the metals Pb and Zn results, with SK. DG BPOM No.03725/ B / SK / VII / 89 maximum of metal contamination in food. In this study, the sampling method used is the method of random sampling in which sampling method from a single population and each population has an equal chance to be selected as sample. Analysis of heavy metal Pb in all samples showed uptake results ranged from 0.0000 to 0.0005, or may be heavy metal pollution Pb is very small. Total Pb (lead) was much less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of the storage temperature. Analysis of Zn metal in the samples showed varying results, it is because the meat itself was contained zinc metal content. Total Zn (Zinc) also was less after storage in the refrigerator for 1 day of corned beef packaging consumables, it is possible the influence of storage temperature affect the metal content. Analysis of Pb (lead) and Zn (zinc) in a sample of corned beef canned consumables still below the threshold set by decree. SNI No. 7387:2009 above the maximum limit of metal contamination in food, so the packaging corned beef is still suitable for consumption and circulated in the market.Key words: Corned Meat Packaging Cans, Metal Pb, Zn Metal, Storage
Co-Processed Laktosa-Metilselulosa Sebagai Zat Tambahan Tablet Dengan Metode Kempa Langsung Mursyid, A. Mumtihanah; -, Nurlina; Mustakim, Musfira
Media Farmasi Indonesia Vol. 12 No. 1 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (161.395 KB)

Abstract

ABSTRAK Co-processing is a technique to obtain a new excipient by combined two or more excipients with an appropriate process. Excipient by co-processing can improve the properties of excipient. The purpose of this research is to produce an excipient with good properties by co-processed Lactosa-Methylcellulosa, so that it is can be use as an excipient for direct compression tablet. This research was compared co-processed Lactosa-Methylcellulosa fabricated by wet milling technique. The co-processed material obtained were evaluated; particle size distribution, average diameter, density, porosity, carr’s index, flowability,compactibility and DSC. And they have been compared with their’s physical mixture. The flowability of co-processed Lactosa-Methylcellulosa was increasedbased on measurement by angles of reposewho did’nt passed 25o, in the range of 16.16 ± 0.63 to 18.59 ± 1.29 and the tensile strength of co-processed Lactosa-Methylcellulosa was increased until 1.79 MPa was higher than it’s physical mixturewere not can be measured tensile strength because the tablet not be able to be developed whole.DSC result of co-processed had similiar pattern with Lactosa. The co-processed Lactosa-Methylcellulosa is more promising to use as direct compression material.
STUDI INKOMPATIBILITAS DAN INSTABILITAS SEDIAAN EXTEMPORANEOUS PULVERES VITAMIN C DARI RUMAH SAKIT IBU DAN ANAK MASYITA MAKASSAR Mursyid, A. Mumtihanah; Purnamasari, Vina; Syam, Adinda
Jurnal Kesehatan Tambusai Vol. 5 No. 3 (2024): SEPTEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i3.33038

Abstract

Pelayanan kefarmasiaan di rumah sakit bertujuan meningkatkan kualitas hidup pasien melalui layanan farmasi yang bertanggung jawab, mencakup informasi, edukasi, serta monitoring penggunaan obat oleh apoteker, termasuk obat racikan. Obat racikan Extemporaneous pulveres sering digunakan untuk pasien anak yang kesulitan menelan tablet atau kapsul, namun memiliki risiko inkompatibilitas dan instabilitas yang dapat mempengaruhi efektivitas dan keamanan obat. Penelitian ini dilakukan di Rumah Sakit Ibu dan Anak Masyita di Makassar untuk mempelajari profil inkompatibilitas dan Instabilitas sediaan Extemporaneous Pulveres Vitamin C melalui observasi fisik dan analisis kadar. Metode yang digunakan adalah pengamatan perubahan fisik dan analisis kadar vitamin C pada sediaan racikan di rumah sakit tersebut. Hasil penelitian menunjukkan adanya potensi Inkompatibilitas dan Instabilitas pada sediaan racikan Vitamin C, terutama karena fotolisis yang menyebabkan degradasi. Kesimpulan dari penelitian ini adalah pentingnya perhatian lebih terhadap stabilitas dan kompatibilitas sediaan Extemporaneous Pulveres untuk memastikan efektivitas dan keamanan obat. Penelitian ini diharapkan memberikan manfaat teoritis sebagai sumber data ilmiah dan manfaat praktis bagi apoteker dalam mengevaluasi sediaan Extemporaneous yang mereka racik.
PROFIL PENGELOLAAN OBAT DI RSKD IBU DAN ANAK SITI FATIMAH KOTA MAKASSAR Said, Mohammad Septiansyah Miftahul; Mursyid, A. Mumtihanah; Aztriana, Aztriana
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 2 (2024)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i2.219

Abstract

Pengelolan obat merupakan pelayanaan manajerial rumah sakit yang merupakan suatu siklus kegiatan dimulai dari pemilihan, perencanaan kebutuhan, pengadaan, penerimaan, penyimpanan, pendistribusian, pemusnahan dan penarikan, pengendalian, serta administrasi yang diperlukan bagi kegiatan Pelayanan Kefarmasian. Tujuan dari penelitian ini adalah untuk mengetahui dan menyajikan data tentang pegelolaan obat dalam bentuk deskriptif di RSKD Ibu dan Anak Siti Fatimah Kota Makassar. Penelitian ini dilakukan dengan metode kombinasi kualitatif dan kuantitatif yang disajikan secara deskriptif. Dari hasil penelitian diketahui bahwa Profil Pengelolaan Obat di RSKD Ibu dan Anak Siti Fatimah Kota Makassar untuk tahap Pemilihan, Perencanaan Kebutuhan, Pengadaan, Pendistribusian, Pemusnahan dan Penarikan, Pengendalian, dan Administrasi telah sesuai dengan regulasi yang berlaku dengan persentase kesesuaian mencapai 100% dan termasuk dalam kriteria Sangat Baik, sedangkan untuk tahap Penerimaan hanya mencapai persentase kesesuaian 77,77% dan termasuk dalam kriteria Baik, dan untuk Penyimpanan hanya mencapai persentase kesesuaian 92,98% dan termasuk dalam kriteria Sangat Baik. Kesimpulan pengelolaan obat di RSKD Ibu dan Anak Siti Fatimah belum sepenuhnya sesuai dengan standar regulasi Permenkes Nomor 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian di Rumah Sakit dan Petunjuk Teknis Standar Pelayanan Kefarmasian di Rumah Sakit Tahun 2019.
A LITERATUR REVIEW : VCO SEBAGAI ANTI KETOMBE Aliefia, Nur; Mursyid, A. Mumtihanah; hasrawati, A.
Makassar Pharmaceutical Science Journal (MPSJ) Vol 2 No 4 (2025)
Publisher : PHARMACY UMI JOURNAL SYSTEM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/mpsj.v2i4.292

Abstract

Hair serum has become a popular care product to maintain healthy and beautiful hair. Pure coconut oil (VCO) is known to have great potential in hair care because of its natural nutritional content. One of the main ingredients in VCO is lauric acid. The high lauric acid content in this vco has antimicrobial and antifungal properties which are effective against dandruff. Dandruff is flakes of (dead) scalp that peel off. The epithelium that makes up the scalp is a stratified squamous epithelium that continuously grows, thereby pushing the old epithelium above it to the surface where it will then die and eventually peel off (corneocytes). Where the use of VCO can prevent dandruff. However, VCO is not applied directly to the scalp, therefore a serum preparation is made first. The advantage of serum compared to other preparations is that it is highly concentrated so it is absorbed more quickly into the skin. Based on the many health problems that often occur on the scalp and hair, the aim of the research is to conduct a literature review on what ingredients are contained in VCO so that it can be made into a hair serum preparation. The method used in reviewing this article is to carry out online search process using several search engines such as Google Scholar, Scopus, and Schoolar with the keywords: Virgin Coconut Oil, Dandruff, Emulgel, Serum. The sources obtained are international and national journals. Articles were selected based on inclusion criteria, namely those published in the last 10 years with suitability for writing keywords, relevance of writing results and discussion.