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All Journal Journal of General Procedural Dermatology and Venereology Indonesia Folia Medica Indonesiana
Alfieri, Alessandro
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Neuroscience

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Allergen profile of facial ACD to cosmetics among patients at Tertiary Referral Hospital in Yogyakarta Alfieri, Alessandro; Indrastuti, Niken; Febriana, Sri Awalia; Pudjiati, Satiti Retno; Waskito, Fajar
Journal of General - Procedural Dermatology & Venereology Indonesia Vol. 6, No. 1
Publisher : UI Scholars Hub

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Background: Cosmetics are a part of life for most of the population and may cause allergic contact dermatitis (ACD), especially on the face, as the primary exposure of cosmetics is on the face area.Methods: This research was conducted retrospectively using secondary data. The research subjects and demographic data were taken from the registered list of patients at Dermatology and Venereology Outpatient Clinic Dr. Sardjito General Hospital with a clinical picture of facial ACD due to cosmetics. Patch tests were carried out from January 2017 to December 2020.Results: From three years period, 26 patients were diagnosed with suspected facial ACD due to cosmetics and underwent patch tests. Of the total 26 patients, 3 patients did not show any reaction to the patch test. On the 23 patients who had reactions on the patch test, there were 66 points on the skin that showed a reaction to allergens. Of the 66 points, 37 points gave a positive reaction picture, with the most common allergen causing the reaction being cobalt(II) chloride hexahydrate (n=4, 10.8%). Then, from 29 points that gave doubtful reactions, the allergen that caused the most reactions was potassium dichromate 0.5% (n=4, 13,8%).Conclusion: The allergens that most often give a positive or doubtful reaction on the patch test of this study are metal compounds (cobalt and potassium dichromate). This study only looks at the patch test that gives a reaction without looking at the clinical relevance related to cosmetics use.
CLINICAL OUTCOMES OF ELECTROSURGERY FOR MANAGEMENT OF GIANT CONDYLOMA ACUMINATA: A SYSTEMATIC REVIEW Eviani, Fortunia Mona; Stella, Maureen Miracle; Budiyanto, Arief; Pudjiati, Satiti Retno; Alfieri, Alessandro
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Giant condyloma acuminata (GCA) is a rare sexually transmitted disease that is locally aggressive with a high recurrence rate. Electrosurgery is a minimally invasive procedure that may be less expensive, quicker, and safer than conventional surgery. This study aimed to review the management of GCA with electrosurgery. We followed PRISMA 2020 guidelines to search and retrieve literature in the following databases: PubMed, ProQuest, Taylor & Francis, ScienceDirect, JSTOR, and SAGE without time restrictions. The study inclusion criteria were original articles that studied the outcome of electrosurgery in GCA. The authors evaluated the risk of bias using the Joanna Briggs Institute (JBI) risk-of-bias assessment. From 572 studies, seven were selected. All studies were published in English between 1997 and 2024. The affected regions in the studies include anal/perianal/anorectal (n=6), vulva (n=2), penis (n=2), scrotal (n=1), vagina (n=1), and suprapubic (n=1). Electrosurgical methods used were electrocautery, electrosection, and electrofulguration, with or without adjunctive treatments. Most cases achieved initial clearance, although one case had a rapid recurrence despite multiple interventions and progressed to squamous cell carcinoma. Recurrence was reported in three cases overall, with timing ranging from weeks to months after treatment. A few adverse effects were infrequent and included a burning sensation during application, minor bleeding, depigmentation, superficial atrophic scarring, and a small remnant ulcer. Electrosurgery demonstrates great potential in treating GCA, particularly when combined with other treatment modalities. However, none of the studies was a randomized controlled trial (RCT). To strengthen the evidence base, RCTs are definitely required.
Co-Authors Arief Budiyanto Eviani, Fortunia Mona Fajar Waskito Febriana, Sri Awalia Niken Indrastuti Satiti Retno Pudjiati Satiti Retno Pudjiati Stella, Maureen Miracle