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Suman Saha, Suman
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Medicine & Pharmacology

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Design and optimization of immediate release tablet of salbutamol sulphate by direct compression technique Saha, Suman
Journal of Applied Pharmaceutical Research Vol. 6 No. 3 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (407.472 KB) | DOI: 10.18231/2348-0335.2018.0010

Abstract

This study is about a tablet, which disintegrates or dissolves quickly when placed in the oral cavity. Studies on formulation development of Salbutamol Sulphate Immediate Release Tablet, suitable for manufacturing by direct compression have been carried out. Trial formulations using various excipients were developed and evaluated for various qualities like hardness, friability, disintegration time, content uniformity and dissolution. Study concluded that Immediate Release Tablet of Salbutamol Sulphate can be prepared successfully with added patient benefit and increased consumer satisfaction.
Immediate release drug delivery systems: a current update Saha, Suman
Journal of Applied Pharmaceutical Research Vol. 6 No. 4 (2018)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.976 KB) | DOI: 10.18231/2348-0335.2018.0011

Abstract

Instead of tremendous advancements in drug delivery, the oral route remains the most preferred route for the administration of therapeutic agents because of the low cost of therapy and ease of administration that leads to high levels of patient concordance. Incorporating an existing medicine into Newer Drug Delivery System (NDDS) are gaining popularities. One such approach is to formulate Immediate Release Tablet, which dissolve or disintegrate rapidly in saliva without the need of water within few seconds due to action of superdisintegrant in the formulation or other novel manufacturing technique. The demand for orally disintegrating tablets has enormously increased during the last decade over the other oral dosage forms (such as tablets, capsules, dry syrups, chewing gums, chewable tablets etc.) particularly for geriatrics and pediatrics, travelers, dysphasics, psychotics and non-cooperative patients. Considering the advantages of Immediate Release Tablet and its growing demand, an attempt has been made through this article to give an overview of preparation and new methodologies for the Immediate Release Tablet followed currently and in past including some patient information.
Autism: a curse on today’s society Sarkar, Snehashis; Choudhury, Ananta; Saha, Suman; Dey, Biplab Kumar
Journal of Applied Pharmaceutical Research Vol. 8 No. 1 (2020)
Publisher : Creative Pharma Assent

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (353.39 KB) | DOI: 10.18231/j.joapr.2019.v.8.i.1.001

Abstract

Autism is a group of neurodevelopment disorders characterized by impaired communication, impaired social interaction and restricted, repetitive and stereotyped patterns of behaviours or interests in the first 3 years of life. It shows a strong male bias and found four times more in males than in females. According to a study in the US, in 2014, overall 1.68% of victims were reported to have Autism Spectrum Disorder (ASD), whereas the percentage was increased by 15% and 150% respectively over the year 2012 and 2000. Numerous genes have been discovered that have roles in ASD but still a good understanding of the pathophysiological process of ASD is not established. ASD costs are estimated to be approximately $250 billion annually in the U.S. Moreover, it is suggested that by 2025, ASD costs will rise to over $450 billion. Thus, the financial burden on families is increasing. There is no effective screening tool for proper diagnosis is available. Based on Infant Toddler Checklist (ITC) and Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5) some tests like ADOS-G, ADI-R, CARS etc. are used for diagnosis. There are medications to cure symptoms but no single medication for ASD. However, some therapies (like ABA- Applied Behavioural Analysis, DTT- Discrete Trial Training, and Symptomatic treatments, etc.) are there that show positive responses towards improvement from a disease state. Some crucial advancement has been achieved in the last decades. Here in the work we have focused on the diagnostic methods and treatment available for the symptoms of Autism. So, it can be said that the day is not too far away when the remedy to cut the curse of autism will be in our hands.
Co-Authors Amit Roy, Amit Ananta Choudhury, Ananta Bhupendra Pradhan, Bhupendra Dey, Biplab Kumar Monika Chauhan, Monika Narendra Kumar Pragya Baghel, Pragya Ranabir Chanda, Ranabir Sanjib Bahadur, Sanjib Sarkar, Snehashis Sujoy Das, Sujoy