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All Journal Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Journal of Innovative and Creativity
Julia Susanti
Universitas Sari Mutiara Indonesia
Education Health Professions Languange, Linguistic, Communication & Media Mathematics Public Health Social Sciences Other

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Effectiveness Test Of The Inhibition Power Of Ethanol Extract Of Salak Pondoh Fruit Skin (Salacca Zalacca (Gaertn.) Voss) Against Eschericia Coli Bacteria And Salmonella Typhi Bacteria Manahan Situmorang; Widya Fitri; Julia Susanti; Enjelina Br Sembiring Kembaren
Journal of Innovative and Creativity Vol. 5 No. 2 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i2.2058

Abstract

Diarrhea is the occurrence of defecation with a more liquid consistency than usual and may be accompanied by liquid mucus or blood with a frequency of three times or more within 24 hours. Salak pondoh contains chemical compounds consisting of flavonoids, saponins, phenols, tannins, alkaloids, chlorogenic acid, ferulic acid, and protocatechuic acid. The bacteria Escherichia coli and Salmonella typhi cause diarrhea and fever due to tissue damage. Based on the above description, this study will test the effectiveness of the inhibitory power of the ethanol extract of salak pondoh fruit skin (Salacca zalacca (Gaertn.) Voss) against Escherichia coli and Salmonella typhi bacteria. This research method uses an experimental agar diffusion method to test the antibacterial activity of salak pondoh fruit skin with concentrations of 20%, 40%, 60%, and 80%. The results of this study show that the concentrations of 20%, 40%, 60%, and 80%, and the positive control (chloramphenicol) of salak pondoh fruit skin have antibacterial inhibitory power against the growth of Escherichia coli bacteria, as indicated by inhibition diameters of 4.81 ± 22.74 mm, 7.81 ± 22.74 mm, 10.15 ± 06.65 mm, 15.07 ± 19.00 mm, and 27.56 ± 48.58 mm, respectively. For Salmonella typhi, the antibacterial inhibitory power was 2.22 ± 18.19 mm, 3.48 ± 23.30 mm, 7.32 ± 67.41 mm, 11.68 ± 112.07 mm, and 24.14 ± 77.77 mm, respectively. The conclusion from the results of this study is that the effectiveness test of the ethanol extract of salak pondoh fruit skin (Salacca zalacca (Gaertn.) Voss) can inhibit the growth of Escherichia coli and Salmonella typhi bacteria, and the concentration that can significantly affect bacterial growth inhibition is 80%.
Formulasi Sediaan Body Scrub Ekstrak Etanol Daun Salam (Syzygium Polyanthum (Wight.) Walp) dan Serbuk Beras Putih (Oryza sativa L.) Sebagai Pelembab Kulit Monica Suryani; Julia Susanti; Dumartina Hutauruk
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 2 No. 4 (2024): Oktober: Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v1i4.558

Abstract

Body scrub is a pharmaceutical preparation in the form of a beauty product that functions to smooth the skin of the body and remove damaged skin cells with the help of scrubs. Bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) are plants that are widely used to maintain health, as a traditional medicine and also as an antioxidant. The research method carried out is experimental. The purpose of this study was to formulate ethanol extracts of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) in the form of Body Scrub preparations with concentrations 2, 4, and 6 that can be used as a skin moisturizer. The extract sample uses ethanol solvent, which will be formulated into the form of a Body Scrub preparation, then an examination of the physical quality test of the preparation, irritation test, hedonic test, moisturiser effectiveness test using a skin moisture analyzer is carried out. The results of this study show that the ethanol extract of bay leaf (Syzygium polyanthum) and white rice powder (Oryza sativa L.) can be formulated as a Body Scrub preparation that has met the physical quality requirements of the preparation which has a semi-solid shape, a more concentrated preparation color and a distinctive aroma of bay leaf extract. The preparation shows a homogeneous composition, M/A cream type, spread power range 5.7-6.2 cm, viscosity range 3,800- 4000 cPs, pH 6.4-6.7, non-irritating to the skin and stable in storage for 4 weeks of storage, hedonic value that is very preferred by researchers on the Body scrub F3 preparation. The effectiveness test showed an increase in humidity of 31.59%, which was the best in the preparation of F3 concentration. It can be concluded that the ethanol extract of bay leaf (Syzygium polyanthum (Wight.)Walp) and white rice powder (Oryza sativa L.) can be formulated in Body Scrub preparations that have met the physical quality requirements of the preparation as a skin moisturizer at a concentration of 6%.
Co-Authors Dumartina Hutauruk Enjelina Br Sembiring Kembaren Manahan Situmorang Monica Suryani Widya Fitri