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All Journal EKSAKTA: Journal of Sciences and Data Analysis Jurnal Farmasi Udayana
Renditya Ismiyati
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Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Materials Science & Nanotechnology Medicine & Pharmacology

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Narrative Review: Analisis Fitokimia Dan Manfaat Ekstrak Ketepeng Cina (Cassia alata L.) Sebagai Antijamur Baha Udin; Renditya Ismiyati; Eva Kholifah; Endah Endah
Jurnal Farmasi Udayana Vol. 12, No 1, Tahun 2023
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2023.v12.i01.p08

Abstract

Indonesia is known to have various types of plants that can be used in medicine, one of which is Cassia alata. Cassia alata is a plant that has many properties so it can be used as herbal medicine or traditional medicine. One of the properties of the Cassia alata plant that has been widely studied is as an antifungal. Every part of the Cassia alata plant has secondary metabolites. Cassia alata leaves contain secondary metabolites of alkaloids, steroids, phenols, glycosides, terpenoids and flavonoids. Cassia alata flowers contain flavonoids, tannins and phenolic compounds and saponins. Cassia alata level contains alkaloids, flavonoids, glycosides, phytosterols, quinones, tannins and terpenoids. Compounds that have a role or antifungal activity in Cassia alata are phenolics, tannins, flavonoids, saponins, triterpenoids, steroids, and alkaloids.
Determination of Total Flavonoid Content and Characterization of Nanoparticles of Kecombrang Leaf Extract (Etlingera elatior (Jack) R.M.Sm.) Hayati, Farida; Sofi Nurmay Stiani; Renditya Ismiyati
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 6, ISSUE 1, April 2025
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/EKSAKTA.vol6.iss1.art4

Abstract

Kecombrang (Etlingera elatior (Jack) R.M.Sm.) is one of Indonesia's potential plants that contain such bioactive compounds as polyphenols, alkaloids, flavonoids, steroids, saponins, and essential oils. This study aims to determine the total flavonoid content of kecombrang leaf extract. It also defines the characteristics of the nanoparticles of kecombrang leaf extract. Kecombrang leaves were extracted through maceration. The determination of the total flavonoid content by spectrophotometry used quercetin as a comparison. The synthesis of nanoparticles used ionic gelation with 0.1% sodium alginate and 0.01% calcium chloride crosslinkers. The characteristic parameters of the nanoparticles of kecombrang leaf extract included the visual, transmittance, adsorption efficiency, particle size distribution, polydispersity index, and zeta potential. The yield value was 46.55%. The total flavonoid content was 88.11 mgQE/g with a regression standard curve Y = 0.1022x + 0.0745 and correlation coefficient (r) = 0.9922. The nanoparticle solution provided a clear visual with a particle size and PI of 108.2 nm and 0.311, a transmittance and adsorption efficiency of 94.76% and 93.76%, and a zeta potential of -36 mV. The total flavonoid content was 88.11 mgQE/g. The nanoparticle solution of kecombrang leaf extract has the characteristics that qualify as a nanoparticle preparation.
Co-Authors Baha Udin Endah Endah Eva Kholifah Hayati, Farida Stiani, Sofi Nurmay