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All Journal Jurnal Kesehatan Amanah Journal of Innovative and Creativity Jurnal Pengabdian Ilmu Kesehatan
Niken Luthfiyanti
Program Studi S1 Farmasi Fakultas Ilmu Kesehatan, Universitas Duta Bangsa Surakarta
Education Languange, Linguistic, Communication & Media Mathematics Nursing Public Health Social Sciences Other

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Pendampingan Program Stimulasi Ibu-Anak Cegah Stunting di Posyandu Ngadi Asih Surakarta Darah Ifalahma; Ana yuliana; Niken Luthfiyanti
Jurnal Pengabdian Ilmu Kesehatan Vol. 5 No. 3 (2025): November: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v5i3.5863

Abstract

Integrated Health Post (Posyandu) Ngadi Asih Surakarta implements Integrated Primary Services (ILP) services targeting pregnant women, toddlers, and breastfeeding mothers in support of the zero new stunting program. So far, the implementation has been limited to weighing and measuring. Problems have been identified, including the lack of health services and health education on stunting prevention. This is due to the limited knowledge and skills of cadres. The solution is an innovative Mother-Child Stimulation Program to Prevent Stunting (Prosiacting) at the Ngadi Asih Surakarta Posyandu. The activities carried out are Prosiacting Activation and Capacity Building for cadres in the form of training in Pregnancy Exercises, Baby Massage, and Oxytocin Massage. The implementation method has 6 stages: preparation, apperception, application of science and technology, mentoring, evaluation, and termination. The results of the Mother-Child Stimulation Program Innovation to Prevent Stunting (Prosiacting) have been well implemented at the Ngadi Asih Surakarta Integrated Health Post (Posyandu). Capacity Building activities for cadres were carried out well. The knowledge and skills of cadres have increased after the training, namely Pregnancy Gymnastics skills in the good category (75%), Baby Massage skills in the good category (80%), and Oxytocin Massage skills in the good category (90%). The Mother-Child Stimulation Program to Prevent Stunting (Prosiacting) has been activated. Cadres are committed to implementing the results of the training and Prosiacting routinely once a month during the Toddler Family Development activity. With the stunting prevention stimulation skills possessed by cadres, it is hoped that cadres will be able to independently accompany pregnant women, mothers of infants and toddlers, and postpartum mothers. It is hoped that this program will be routinely implemented at the Ngadi Asih Surakarta Integrated Health Post (Posyandu) as an effort to independently prevent Stunting in the Community.
Evaluasi Kesesuaian Rekonstitusi Sediaan Steril di Bangsal Anak RS Universitas Sebelas Maret Ayu Cahyani Abidin; Hidayah Apriliawan; Niken Luthfiyanti
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

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Abstract

Reconstitution of injectable drugs involved mixing sterile drug powders with appropriate sterile solvents prior to parenteral administration. This critical pharmacy practice was particularly vital in pediatrics where dosing errors and contamination posed significant risks. Reconstitution errors could lead to chemical instability, therapeutic failure, and serious adverse effects including toxicity or nosocomial infections. This study aimed to evaluate the appropriateness of sterile injectable drug reconstitution procedures in the Pediatric Ward of Universitas Sebelas Maret Hospital across five parameters: dosage calculation, solvent selection, solvent volume, post-reconstitution storage temperature, and Beyond Use Date (BUD) assignment. A descriptive observational study with prospective design was conducted among pediatric inpatients from December 2025 to January 2026. Seventy cases of pediatric injectable drug administrations were sampled using saturated (total) sampling technique. Primary data were collected through direct pharmacist reconstitution observations while secondary data came from medical records and sterile preparation worksheets. Compliance was benchmarked against gold standards: Pediatric Injectable Drugs 10th edition and Handbook on Injectable Drugs 17th edition. Perfect compliance (100%) was achieved for dosage, solvent selection (NaCl 0.9%, sterile water), and reconstitution volumes. However, storage temperature compliance (2-8°C for light-sensitive drugs) was only 68%, while BUD documentation aligned with post-reconstitution stability in 70% of cases, leaving 2% critical non-compliance posing patient safety risks. While reconstitution technical execution was excellent, cold chain monitoring and BUD documentation required systemic improvements through regular training, real-time temperature tracking, and stricter Standard Operating Procedures to ensure pediatric pharmacotherapy safety.
Analisis Kadar Flavonoid Total dan Aktivitas Antioksidan dari Ekstrak Etanol Serta Fraksi dari Gagang Cengkeh (Syzygium Aromaticum (L)). Intan Oktaviana Putri; Niken Luthfiyanti; Danang Raharjo
Jurnal Kesehatan Amanah Vol. 9 No. 2 (2025): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v9i2.989

Abstract

Antioxidants are substances that can inhibit oxidation caused by free radicals. Flavonoids are effective natural antioxidants due to their unique chemical structure. Both have a hydroxyl group (-OH) attached to an aromatic ring. This hydroxyl group can donate hydrogen or electrons to free radicals. Clove stems (Syzygium aromaticum (L.)) are known to possess bioactive compounds, including flavonoids like quercetin and kaempferol, which act as antioxidants in protecting cells from free radicals. Maceration is a commonly used extraction method to obtain therapeutic compounds from plants. The process involves soaking the finely or coarsely ground plant material in a solvent (liquid thinner) in a closed container. Fractionation is a method for separating chemical components in an extract based on differences in their polarity or solubility. This process uses two immiscible solvents. This study is an experimental research aimed at determining the total flavonoid content (TFC) and the IC50​ value of the antioxidant activity present in the ethanol extract and fractions of clove stems (Syzygium aromaticum (L.)) using the ABTS method. The tests utilized maceration extraction with 96% ethanol as the solvent, and liquid-liquid fractionation using N-hexane, ethyl acetate, and water as solvents, along with UV-Vis spectrophotometry analysis. The results showed that the highest flavonoid content was in the ethanol extract, with a TFC value of 51.000 mgQE/g, and the highest antioxidant activity was in the ethyl acetate fraction, with an IC50​ value of 23.716 µg/mL, indicating a strong potential as a source of natural antioxidants.
Co-Authors Ana Yuliana Ayu Cahyani Abidin Darah Ifalahma Hidayah Apriliawan Intan Oktaviana Putri