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All Journal Jurnal Kedokteran Brawijaya Nexus Kedokteran Klinik Indonesian Journal of Medicine Bioscientia Medicina : Journal of Biomedicine and Translational Research Biomolecular and Health Science Journal Poltekita: Jurnal Pengabdian Masyarakat Bioscientia Medicina : Journal of Biomedicine and Translational Research Plexus Medical Journal
Nefihancoro, Udi Heru
Departement Of Orthopaedic And Traumatology, Dr. Moewardi General Hospital, Surakarta Program Study Of Orthopaedic And Traumatology, Dr. Moewardi General Hospital, Faculty Of Medicine, Sebelas Maret University, Surakarta
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Effectiveness of Mechanical Treatments (Periosteal Stripping VS Non-Periosteal Stripping) on Fracture Healing: In Vivo Study Udi Heru Nefihancoro; Septriarta Parlindungan; Ida Bagus Budhi Surya Adnyana
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 9 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i9.1071

Abstract

Background: Periosteal stripping (PS) is a controversial technique in fracture management, with studies reporting both positive and negative effects on bone healing. This study aims to evaluate the effectiveness of PS and non-periosteal stripping (NPS) on fracture healing in the Sprague Dawley rat model. Methods: This study is an in vivo experimental research. Male Sprague Dawley rats (8-10 weeks old) were divided into four groups (n=10 per group): Group I: NPS, evaluation day 14; Group II: PS, evaluation day 14; Group III: NPS, evaluation day 28 and Group IV: PS, evaluation day 28. A standard fracture was created in the tibia, and PS or NPS was performed. Radiographic evaluation was performed on days 14 and 28, with the RUST score (Radiographic Union Score for Tibia) used to assess fracture healing. Statistical analysis was performed using the Kruskal-Wallis test. Results: The RUST score showed better fracture healing in the NPS group compared to PS on day 28 (p<0.05). There was no significant difference on day 14 (p>0.05). Conclusion: NPS was more effective in accelerating fracture healing in Sprague Dawley rats than PS, especially in the later stages of healing. These findings provide further evidence of the potential adverse effects of PS and highlight the importance of considering time in assessing its efficacy.
Co-Authors ., Marwoto AMANDA DIAH MAHARANI Angesti Nugraheni Atriany Nilam Sari Bintang Soetjahjo Deni Prasetyo Utomo Dhoni Akbar Ghozali Gilang Teguh Pratama Ida Bagus Budhi Surya Adnyana MAHARANI, AMANDA DIAH Marwoto . Rachmad Faisal Rhyan Darma Saputra Ricat Hinaywan Malik Rieva Ermawan Septriarta Parlindungan Sri Mulyani Vitri Widaningsih