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All Journal Jurnal Farmasindo: Jurnal Penelitian dan Pengabdian Masyarakat
Yunita Dian Permatasari
Politeknik Indonusa Surakarta
Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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FORMULASI KRIM ANTIOKSIDAN EKSTRAK BUAH KURMA (Phoenix dactylivera L.) DENGAN VARIASI KONSENTRASI BASIS KRIM Hendra Budiman; Yunita Dian Permatasari; Islami Yuniwati
Jurnal Farmasindo Vol 3 No 2 (2019): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Kurma (Phoenix dactylifera L.) termasuk famili Palmae memiliki berbagai macam kandungan nutrisi dan dapat berfungsi sebagai obat. Kandungan antioksidan terbesar kurma adalah flavonoid yang dapat berfungsi sebagai anti-karsinogenik, antimikroba, anti-mutagenik, anti-inflamasi, anti diabetes dan mengurangi resiko kardiovaskular. Krim lebih acceptable karena mudah diaplikasikan ke kulit. Tujuan penelitian ini adalah untuk mengetahui formulasi sediaan krim ekstrak buah kurma dalam penelitian ini yang memberikan sifat fisik yang paling baik. Buah kurma dipotong-potong dan dimaserasi untuk menarik senyawa-senyawa yang terkandung dalam bauh kurma, ekstrak yang diperoleh dipekatkan agar ekstrak lebih awet. Dilakukan formulasi krim ekstrak buah kurma dengan variasi basis krim yaitu cera alba dan vaselin album. Krim yang telah selesai diformulasikan kemudian diuji sifat fisiknya yang meliputi uji organoleptis, uji homogenitas, uji daya sebar, uji daya lekat, uji pH, dan uji daya proteksi. Hasil dari ekstrak buah kurma diperoleh rendemen sebesar 40,97%. Untuk hasil uji sifat fisik krim diperoleh krim yang homogen dengan warna putih kecoklatan dengan bau khas buah kurma. Krim memiliki nilai daya sebar terbesar pada formula 1, dan uji daya lekat yang paling baik pada formula 3. Sedangkan untuk uji pH semua krim memasuki rentang pH yang baik untuk kulit. Uji daya proteksi semua krim memenuhi syarat yaitu tidak menimbulkan warna merah selama 5 menit.
FORMULASI DAN UJI FISIK GEL EKSTRAK DAUN SALAM (Syzygium poliyantum (Wight) Walp) DENGAN GELLING AGENT HPMC (Hydroxypropyl Methylcellulose) Yunita Dian Permatasari; Dwi Islamiyati; Umi Nafisah
Jurnal Farmasindo Vol 4 No 1 (2020): Juni
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Nowdays, medical plants have been widely used for overcome health problem. One of the nutritious plants is Bay Plant (Syzygium poliyantum (Wight) Walp) which contains flavonoid active compound, saponin which contains flavonoid compounds, saponins, which are used as antibacterial. This study aims to determine the gel formulation and evaluation as well as the effect of differences in the concentration of HPMC (Hydroxypropyl Methylcellulose) on the physical properties og the gel. In this study used variations in the HPMC concentrations of 4%, 5% and 6% with bay leaf extract concentrations of 5%. Bay leaves extracted by maceration for 7 days, then will be remacerated for 2 days to find the compouds that were still left with 70% ethanol solvent. Gel evaluation includes organoleptic, spread power, adhesion, pH, homogeneity, and protection. The evaluation result showed that at a concentration of HPMC 4%, 5% and 6% each had a distinctive odor of bay leaf extract and brown colored in an organoleptic test, produced homogeneus preparations, had a pH value of 6,16; 5,82; and 5,73; spread power 6,2 cm; 5,8 cm; and 5,1 cm; Stickness 5,75 sec; 7,46 sec; and 9.35 sec; and protective power 6,57 sec; 6,87 sec; 6.89 sec. The results of pH test, spreadability, and stickness using Kruskal Wallis showed an Asymp.Sig < 0.05% that is 0.000, which indicates that there are significant difference between the concentration of HPMC with ph test, spreadability and stickness. The result of protective power test showed an Asymp.Sig > 0.05 that is 0.497 and there is no significant difference between the concentration of HPMC with the protective power. The result of testing all three formulas meet the requirements except for protective power.
FORMULASI DAN UJI FISIK SEDIAAN SALEP EKSTRAK DAUN JAMBU AIR (Syzygium aqueum (Burm F.) Alston) DENGAN VARIASI TIPE BASIS SALEP Yunita Dian Permatasari; Nava Kirani; Umi Nafisah; Aptika Oktaviana Trisna Dewi
Jurnal Farmasindo Vol 4 No 2 (2020): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Water guava leaves contain chemical compounds such as flavonoids, tannins and saponins. As a medicinal preparation, water guava leaves can be made into an ointment. This study aims to determine the ointment formulation, conduct physical evaluation of the ointment and determine the effect of different types of ointment base extracts of water guava leaves on physical properties. Water guava leaves extract was made by maceration method of ethanol 70% solvent. Ointment are made with four types of bases which include hydrocarbon base, absorption, water washed and water soluble. Each formula was tested for physical properties including organoleptic, homogeneity, pH, dispersal, and adhesion. The data obtained were then analyzed using the One Way ANOVA test method. The results showed that the four ointment formulas had different shapes and colors, had the same odor and had good homogeneity. The pH test of the hydrocarbon bases ointment was 4.09, the absorption bases was 3.98, the water-washed bases was 4.33, and the water-soluble base was 3.87 did not meet the pH test parameters. The dispersibility test results for hydrocarbon bases 6.20 cm, absorption basis 6.19 cm met the test parameters, base ointment was washed with water 3.99 cm, water soluble base 3.49 cm did not meet the dispersibility test parameters. The results of the adhesion test for hydrocarbon bases 11.85, absorption bases 12.11, water washable bases 20.03, and water soluble bases 4.97, which means they meet the adhesion test parameters. The results of the One Way ANOVA test showed that the pH test, spreadability and adhesion had the same significant value, namely 0.000 <0.05. These results indicate that the different types of ointment bases used have a significant effect on pH, dispersion and adhesion.
EVALUASI WAKTU TUNGGU PELAYANAN RESEP PASIEN RAWAT JALAN DI PUSKESMAS JUMAPOLO KABUPATEN KARANGANYAR Yunita Dian Permatasari; Riyan Setiyanto; Siti Asijah; Reni Safira Arum Sari; Anisa Animarsela
Jurnal Farmasindo Vol 5 No 2 (2021): Desember
Publisher : Program Studi D3 Farmasi Politeknik Indonusa Surakarta

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Pelayanan farmasi termasuk dalam salah satu jenis pelayanan kesehatan minimal yang wajib disediakan oleh Puskesmas. Pelayanan farmasi meliputi pelaynan sediaan farmasi dan pelayanan farmasi klinik yang didalamnya membutuhkan waktu pengerjaan, sehingga timbul waktu tunggu pelayanan. Waktu tunggu pelayanan resep dimulai dari pasien menyerahkan resep sampai dengan menerima obat yang disertai pemberian Komunikasi Informasi dan Edukasi (KIE). Tujuan dari penelitian ini adalah mengetahui rata-rata waktu tunggu pelayanan resep pada Puskesmas Jumapolo Kabupaten Karanganyar. Jenis penelitian ini adalah penelitian survei descriptif cross sectional. Teknik pengumpulan data dalam penelitian ini melalui pengamatan langsung/observasi dengan menggunakan lembar evaluasi waktu tunggu. Jumlah sampel sebanyak 292 resep yang terdiri dari 265 resep non racikan dan 27 resep racikan. Evaluasi dilakukan dengan membandingkan rata-rata waktu tunggu pelayanan resep dengan standar yang berlaku. Hasil penelitian menunjukkan bahwa rata-rata waktu yang dibutuhkan untuk menyelesaikan resep non racikan selama 14,9 menit dan resep racikan selama 15,3 menit. Hal tersebut menunjukkan pelayanan resep telah sesuai dengan standar pelayanan minimal rumah sakit pada Keputusan Mentri Kesehatan Republik Indonesia Nomor:129/Menkes/SK/II/2008 dan standar waktu tunggu pelayanan resep untuk resep non racikan yaitu kurang dari 30 menit dan untuk resep racikan yaitu kurang dari 60 menit.
Co-Authors Anisa Animarsela Aptika Oktaviana Trisna Dewi Dwi Islamiyati Hendra Budiman Islami Yuniwati Nava Kirani Reni Safira Arum Sari Riyan Setiyanto Siti Asijah Umi Nafisah