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Sharon Aurelia
4Laboratory Animal Management, School of Veterinary Medicine and Biomedical Science, IPB University, Bogor 16680, West Java, Indonesia4Laboratory Animal Management, School of Veterinary Medicine and Biomedical Science, IPB University, Bogor 16680, We
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Veterinary

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COMBINATION OF BASIL, TURMERIC AND BEAN SPROUTS TO HEMATOLOGY AND BIOCHEMISTRY OF FEMALE RAT BLOOD BEFORE PREGNANCY Andriyanto Andriyanto; Aulia Andi Mustika; Wasmen Manalu; Mawar Subangkit; Sharon Aurelia; Leliana Nugrahaning Widi; Hamdika Yendri Putra; Elpita Tarigan; Yusa Irarang
Jurnal Kedokteran Hewan Vol 17, No 4 (2023): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v17i4.33189

Abstract

The purpose of the study was to examine the safety of combination of basil, turmeric and bean sprouts extract solution on the hematological parameters and blood biochemistry profile of rats. The combined ingredients used in the study were obtained from different places. A total of 15 rats were divided into 3 groups based on the treatment dose. Each group consisted of 5 rats. The rats in control group (K) did not given extract combination, while the rats in group KKT 1 % and KKT 5% received combination of basil, turmeric and bean sprouts extract at dose of 1% and 5%, respectively. Effectiveness and safety tests were carried out by evaluating the hematological and blood biochemical profiles of female rats. The data were analyzed using one-way analysis of variance (ANOVA). The results showed that the rats given combination of basil, turmeric and bean sprouts extract at a dose of 1% and, dose of 5% did not had significant different compared to control (P0.05), but tend to have positive effects in increasing  several blood components that play an important role in maintaining immunity during pregnancy. It can be concluded that the combination of basil, turmeric and bean sprouts at dose of 1% and 5% do not adversely affect hematology profile and blood biochemistry of rats. This indicates that the extract combination does not cause any toxicity effects on the rats.
Co-Authors Andriyanto Andriyanto Aulia Andi Mustika Elpita Tarigan Hamdika Yendri Putra Leliana Nugrahaning Widi Subangkit, Mawar Wasmen Manalu Yusa Irarang