Article Per Year (5 Year)
p-Index From 2021 - 2026
1.583
P-Index
This Author published in this journals
All Journal Smart Medical Journal Majalah Kedokteran Neurosains Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Neurona Acta Neurologica Indonesia
Taufik Mesiano
Divisi Neurovaskular Departemen Neurologi FK Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta
Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Neuroscience Public Health

Published : 20 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 20 Documents
Search

 1   2 
KEJADIAN STROKE ISKEMIK PADA PASIEN POSITIF COVID-19 TERKONFIRMASI DI RUMAH SAKIT UNIVERSITAS INDONESIA Rakhmad Hidayat; Gemia Clarisa Fathi; Ramdinal Aviesena Zairinal; Raden Rara Diah Handayani; Mohammad Kurniawan; Taufik Mesiano; Al Rasyid; Salim Harris
NEURONA Vol 38 No 2 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Coronavirus disease 2019 (COVID-19) is not only disrupts the respiratory system, it can disrupt various organ systems, one of which is the central nervous system. Indonesia still has a little literature that discusses COVID-19 and its relation to ischemic stroke. This study aims to report the course of ischemic stroke cases in patients who have been confirmed positive for COVID-19. A 56 year old man presented with confirmed COVID-19, the patient had a history of type 2 diabetes mellitus and also a history of dyslipidemia. At initial presentation the patient did not complain of neurological symptoms, but after 12 days of treatment the patient complained of weakness in the left side of the upper leg. The CT scan of the head with contrast revealed an infarction in the peripheral area, perfusion CT found that the patient was hypoperfused in the right cerebral hemisphere area without the presence of a large core infarction or a clear perfusion mismatch defect. CT angiography did not reveal stenosis or occlusion of the large vessels. It can be concluded that ischemic stroke in COVID-19 patients can occur due to various underlying factors, one of which is hypercoagulability. Keywords: COVID-19, Stroke, Universitas Indonesia Hospital
PROFIL KLINIS DAN LUARAN STROKE ISKEMIK AKUT DENGAN TROMBEKTOMI MEKANIK BERDASARKAN LOKASI OKLUSI DI RSUPN DR. CIPTO MANGUNKUSUMO Kevin Kevin; Taufik Mesiano; Mohammad Kurniawan; Rakhmad Hidayat; Affan P. Permana; Al Rasyid; Salim Harris
NEURONA Vol 38 No 3 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Occlusion in anterior circulation gives variable clinical manifestations. Mechanical thrombectomy promises almost two times higher recanalization rate as opposed to thrombolysis. Aim: To evaluate the clinical and outcome profile of acute ischemic stroke patients who underwent mechanical thrombectomy based on the occlusion site. Methods: This was a retrospective cohort conducted at Cipto Mangunkusumo National Referral Hospital from May 2017 to January 2020. All acute ischemic stroke patients in anterior circulation who underwent mechanical thrombectomy with or without bridging intravenous thrombolysis were analyzed. Occlusion site and recanalization rate were scored based on arteriogram. Results: Sixteen patients had occlusion in ICA-M1 segment, while ten others were in the M2 segment. NIHSS value was two points higher in ICA-M1 occlusion (p>0.05), which further analysis found that the proportion of aphasia manifestation was higher in the ICA-M1 segment (50.0% vs 20.0%; p=0.218). Demographical and clinical characteristics were similar between the two groups. Thrombolysis did not modify the occlusion site on thrombectomy (p>0.05). Despite statistical insignificancy, ICA-M1 occlusion showed an earlier time trend from admission to recanalization. The M2 segment had a higher proportion of mTICI 2b/3 recanali????ation (50.0% vs 70.0%; p=0.428) and mRS 0-2 on discharge (12.5% vs 50.0%; p=0.053). Discussion: Aphasia was more common in proximal occlusion???? which drove family members to bring patients earlier to the hospital. The functional outcome on discharge was lower in proximal occlusion due to more extensive and permanent brain tissue loss. Future coordination is warranted to improve the therapeutic time from admission to recanalization. Keywords: functional outcome, ischemic stroke, mechanical thrombectomy, occlusion site
SINDROM PIRAMIDAL BILATERAL MENYERUPAI KLINIS SINDROM GUILLAIN-BARRE Putri Auliya; Ahmad Yanuar Safri; Taufik Mesiano; Winnugroho Wiratman; Fitri Octaviana; Manfaluthy Hakim
NEURONA Vol 38 No 4 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

A 35-year-old man came with weakness in all four limbs with ascending paralysis. The patient experienced a weakness in the right leg initially, followed by the left leg within three hours and involved both arms within one day. The patient was taken to the emergency room afterwards, and within four days, the patient developed tetraplegia, experienced weaknesses of the vocal cord and must be assisted by the ventilator. Lumbar puncture and plasmapheresis were performed, but no improvement was seen. Subsequently, the patient underwent magnetic resonance imaging (MRI) and obtained a picture of subacute infarction on bilateral medulla oblongata pyramidal seen in ????heart shape????. Patients were rehabilitated and given secondary stroke preventive therapy. Clinical findings in this patient were very similar to the clinical findings in Guillain-Barre Syndrome as this cause delayed diagnosis and therapy of the stroke. Both of these two syndromes can be life-threatening because respiratory failure can occur. Keywords: Bilateral pyramidal syndrome, GBS, Guillain-barre syndrome, stroke
KEJADIAN IKUTAN NEUROLOGIS PADA TENAGA KESEHATAN RUMAH SAKIT RUJUKAN COVID-19 PASCA VAKSINASI MRNA-1273 BOOSTER Rakhmad Hidayat; Muhammad Hafiz Aini; Zlatikha Djuliannisaa; Alyssa Putri Mustika; Mohammad Kurniawan; Taufik Mesiano; Al rasyid; Salim Harris
NEURONA Vol 38 No 4 (2021)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Vaccine effectivity to decrease COVID-19 transmission has been proven by the decrease in hospitality rate and death rate caused by COVID-19. Nowadays, Indonesian health workers are fully vaccinated for more than six months. The government want to give mRNA-1273 (Moderna) vaccine as the third vaccine dose booster for health workers. The booster’s effect remains unknown, but there are some vaccine side effects. Aim: To know the neurological side effects of the Moderna vaccine that are still unknown and not yet studied in Indonesia. Methods: This study used a prospective cohort with the primary data collected through an online form filled by health workers of Universitas Indonesia Hospital that get Moderna vaccine as a booster. Research data analysis will be carried out through a comparative study through the chi-square method using SPSS 20. Results: The previous history of adverse events following immunization (AEFI) significantly affects the type, the severity degree, and the acceptance of AEFI after the Moderna vaccine booster. BMI and regular medication affect the severity degree of AEFI (P<0.05). Regular medication insignificantly increases the possibility of no side effects. Meanwhile, the use of antipyretic medication for AEFI in????uenced the history of previous AEFI (P<0.05). Discussion: AEFI is any untoward medical occurrence that follows immunisation and does not necessarily have a causal relationship with the usage of the vaccine. Further investigation is necessary to evaluate the correlation between those factors and the AEFI of the Moderna booster vaccine. Keywords: COVID-19, health workers, Moderna vaccine, vaccine side effects
Spinal Cord Compression Due to Intradural Extramedullary Hematopoiesis in a Young Adult with Cooley’s Anemia Mesiano, Taufik; Rasyid, Al; Kurniawan, Mohammad; Hidayat, Rakhmad; Pangeran, David; Lubis, Anna Mira; Saekhu, Mohamad; Gunawan, Kevin; Putri, Stefanie Karina; Rahmana, Arizari Haj; Harris, Salim
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.4

Abstract

Cooley's anemia, also known as beta thalassemia major, is an inherited multisystemic disorder characterized by skeletal and non-skeletal complications resulting from hemoglobinopathies. Extramedullary Hematopoiesis (EMH) is a complication of thalassemia major due to insufficient erythropoiesis expansion. The incidence rate of paraspinal EMH in beta-thalassemia is rare but tends to be on the rise. We present a case of spinal cord compression due to intradural EMH in a 21-year-old man with Beta Thalassemia major, who exhibited acute lower motor, sensory, and autonomic disorder, along with severe anemia, and electrolyte imbalance. Patients were treated with corticosteroids, blood transfusions, electrolyte correction and pain medications. Several days later, the patient experienced clinical improvement in reduced pain and motor improvement. The patient was planned to undergo elective surgery and radiotherapy after reaching the stabilized condition. Management options of spinal cord compression due to EMH include corticosteroids, adequate blood transfusion, hydroxyurea, radiotherapy, surgical decompression, exchange transfusion, or a combination of these approaches. The choice of therapy should be based on the patient's clinical condition, diagnostic evaluations, and the size of the mass exerting pressure on the spinal cord. The optimal management of EMH remains uncertain. We need further research to establish effective treatment strategies of spinal cord compression due to EMH in Cooley’s Anemia.
Nosocomial COVID-19 Infection in Acute Neurological Diseases at the Indonesian National Referral Hospital Mesiano, Taufik; Tunjungsari, Dyah; Budikayanti, Astri; Ramli, Yetty
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.6

Abstract

Introduction: Neurological diseases elevate the susceptibility to respiratory tract ailments. This study aims to evaluate the incidence of nosocomial coronavirus disease 2019 (COVID-19) among non-COVID neurology inpatients and identify associated risk factors. Objective: To assess nosocomial COVID-19 infection in non-COVID neurology inpatients and identify associated risk factors. Material and Methods: A prospective cohort study was conducted during the initial wave of the COVID-19 pandemic, encompassing all non-COVID neurology inpatients at Dr. Cipto Mangunkusumo Hospital from May to September 2020. Clinical data were collected, and bivariate and multivariate analyses were employed to examine risk factors. Result and Discussion: Among 308 subjects, 31 (10.6%) experienced nosocomial COVID-19 infection. Suspect cases constituted 77.4%, probable cases 16.1%, and confirmed cases 6%. Predominant neurological diseases included cerebrovascular disease (36.7%), CNS neoplasm (18.8%), and traumatic brain injury (15.6%). Comorbid diseases increased the infection risk by 6.53 times (95% CI 1.52-28.0), particularly non-CNS malignancy (12.37, 3.7-41.00), chronic pulmonary TB (12.29, 2.7-55.89), and hypertension (3.8, 1.3-11.4). Loss of consciousness and nasogastric tube (NGT) usage elevated the risk by 2.92 (1.37-6.21) and 4.68 (1.95-11.24) times. This study reinforces existing evidence that hospitalized patients with neurological diseases are more susceptible to COVID-19, particularly due to loss of consciousness and NGT usage. The risk is amplified with comorbidities such as non-CNS malignancy, chronic pulmonary TB, and hypertension. Conclusion: Individual neurological diseases alone did not heighten the risk of COVID-19 infection. Notably, factors like loss of consciousness, NGT usage, and comorbid diseases significantly correlate with nosocomial COVID-19 infection in non-COVID neurology inpatients.
Hemorrhagic Stroke as the Manifestation of Neuropsychiatric Systemic Lupus Erythematosus Kurniawan, Mohammad; Nurdin, Ilham; Rasyid, Al; Mesiano, Taufik; Hidayat, Rakhmad; Harris, Salim
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.8

Abstract

Stroke is a major cause of mortality and disability. It can be classified into ischemic stroke and hemorrhagic stroke. Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease that can cause neuropsychiatric systemic lupus erythematosus (NPSLE) complications, one of those manifests as stroke, which happens often in young adults. Ischemic stroke is more common in SLE patient, but hemorrhagic stroke can also ensue. We present a case of SLE in a young woman with left-sided hemiparesis and convulsion. After undergoing clinical evaluation, laboratory testing, and radiological imaging, she was diagnosed with hemorrhagic stroke. She was treated conservatively; blood pressure control, steroid administration to improve the condition, and anticonvulsants.
Optimizing Stroke Care in Indonesia: A Policy Brief on Expanding Access to Thrombolysis for Improved Outcomes Hidayat, Rakhmad; Rima, Siti Pujiwati Permata; Pangeran, David; Mesiano, Taufik; Kurniawan, Mohammad; Rasyid, Al; Harris, Salim
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.12

Abstract

Recurrent Intracerebral Hemorrhage as a Result of Cerebral Amyloid Angiopathy Kurniawan, Mohammad; Lestari, Dhara Ayu; Harris, Salim; Rasyid, Al; Mesiano, Taufik; Hidayat, Rakhmad
Acta Neurologica Indonesia Vol. 1 No. 01 (2023): Acta Neurologica Indonesia
Publisher : Departemen Neurologi Fakultas Kedokteran Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69868/ani.v1i01.13

Abstract

Stroke is a major health problem in the world with high mortality dan morbidity rate. Hemorrhagic stroke is a type of stroke with a high mortality rate. One of the most common causes of hemorrhagic stroke in elderly is cerebral amyloid angiopathy. We present a case of recurrent hemorrhagic stroke with clinical manifestations of extremity weakness and seizure. Radiological imaging showed a lobar hemorrhage. Referring to the Boston criteria, based on the results of clinical evaluation and imaging, the patient was diagnosed with intracerebral hemorrhage et causa probable CAA without pathologic feature was established. Patients were treated with antihypertensive medicine for blood pressure control and steroid as anti-inflammatory agents with a good clinical and functional outcome.
Rekomendasi Sistem Stroke Pendekatan 8D dalam Penanganan Stroke Iskemik Akut Permana, Affan Priyambodo; Nafisah, Zharifah Fauziyyah; Mesiano, Taufik; Yunus, Reyhan Eddy; Sulistio, Septo; Habib, Hadiki; Mulyana, Radi Muharris; Albar, Imamul Aziz
Majalah Kedokteran Indonesia Vol 71 No 1 (2021): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.71.1-2021-162

Abstract

Stroke is the leading cause of death in Indonesia and leading cause of long-termdisability in the world. Ischemic stroke include 85% of all stroke cases. Ischemic stroke is caused by thromboembolic blockage or arterial stenotic by atherosclerotic plaque. Current practice shows that ischemic stroke can be treated. Treatment using intravenous thrombolytic (IV-tPA) and mechanical thrombectomy will provide better outcomes for the patient. It can be achieved when treated kurang dari 4.5 hours since onset for IV-tPA and kurang dari 6-24 hours for large vessel occlusions using mechanical thrombectomy. However, only a small number of patients can achieve this treatment due to lack of society knowledge about the sign and symptoms, transportation problems, and the stroke management system that has not been well established. Every one minute stroke patient is left untreated, 1.9 millions neurons in the brain are dead. An integrated management of the stroke system can provide better outcomes, lower the length-of-stay of the patients in hospital and reduce the cost spent for treatment. One system that is recommended for managing stroke cases is 8D that consist of detection, dispatch, delivery, door, data, decision, drug/device, and disposition. This system will help health care providers to collaborate through a multidisciplinary system for managing acute ischemic stroke cases comprehensively so that stroke patients can get proper handling and better outcomes.
Co-Authors Affan P. Permana Al Rasyid Al Rasyid Albar, Imamul Aziz Alyssa Putri Mustika Andi Ade Wijaya Ramlan Anna Mira Lubis Astri Budikayanti Cipuk Muhaswitri Dinda Diafiri Diyah Eka Andayani Dyah Tunjungsari, Dyah Fitri Octaviana Gemia Clarisa Fathi Hadiki Habib, Hadiki Hirari Fattah Yasfi Kevin Gunawan Kevin Kevin Kurniawan, Mohammad Lestari, Dhara Ayu Mohamad Saekhu Mohammad Kurniawan Muhammad Hafiz Aini Muhammad Kurniawan Mulyana, Radi Muharris Nafisah, Zharifah Fauziyyah Nurdin, Ilham Pangeran, David Permana, Affan Priyambodo Putri Auliya Putri, Stefanie Karina Raden Rara Diah Handayani Rahmana, Arizari Haj Rakhmad Hidayat Rakhmad Hidayat Ramdinal Aviesena Zairinal Ramli, Yetty Reyhan Eddy Yunus Rima, Siti Pujiwati Permata Safri, Ahmad Yanuar Salim Harris Salim Harris Salim Harris Salim Harris Salim Harris Salim Harris, Salim Sulistio, Septo Tiara Aninditha Winnugroho Wiratman Yesi Astri Zlatikha Djuliannisaa