Article Per Year (5 Year)
p-Index From 2021 - 2026
1.066
P-Index
This Author published in this journals
All Journal Magna Neurologica Academic Hospital Journal Neurona Indonesian Journal of Biomedicine and Clinical Sciences
Amelia Nur Vidyanti
Departemen Neurologi, Fakultas Kedokteran, Kesehatan Masyarakat, Dan Keperawatan, Universitas Gadjah Mada, Yogyakarta
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

Published : 6 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Neurona

 1 
Penurunan Kesadaran dan Kejang Berhubungan dengan Peningkatan Mortalitas pada Pasien Covid-19: Studi Retrospektif di Rumah Sakit Umum Dr. Sardjito Yogyakarta Satiti, Sekar; Edyanto, Abdullah Syafiq; Pambudi Sejahtera, Desin; Nalendra Tama, Whisnu; Yuli Firlando, Afdhal; Vidyanti, Amelia Nur
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 39 No 4 (2023): Vol 39 No 4 (2023)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v39i4.381

Abstract

Introduction: Coronavirus infection has been associated with neurologic manifestations. Aim: The aim of this study was to investigate the predictors of mortality based on neurological manifestations among hospitalized COVID-19 patients. Methods: This was a retrospective study on COVID-19 patients hospitalized at Dr. Sardjito General Hospital Yogyakarta, Indonesia from March 9, 2020 to January 28, 2021. Demographic characteristics, medical history, symptoms, and clinical signs were extracted from medical records. Factors associated with the mortality were analysed using multivariate logistic regression analysis. Results: A total of 421 medical records were examined. Among them, 114 individuals died during hospitalization (27.08%). Several baseline characteristics were associated with mortality including age (OR: 1.05, 95%CI: 1.03-1.07, p = 0.000), history of diabetes mellitus (DM) (OR: 3.1, 95%CI: 1.95-4.95, p= 0.000), history of hypertension (OR: 1.88, 95%CI: 1.22-2.92, p= 0.004), and history of renal insufficiency (OR: 3.73, 95%CI: 2.2-6.32, p= 0.000). Neurological manifestation that associated with mortality were loss of consciousness (OR= 34.70, 95%CI: 12.67-95.05, p= 0.000), delirium (OR= 21.01, 95%CI: 3.85-114.51, p= 0.000), and seizure (OR= 31.01, 95%CI: 3.82-251.69, p= 0.001). On the multivariate analysis, loss of consciousness (OR: 33.10, 95%CI: 12.00-91.33, p= 0.000), and seizure (OR: 22.75, 95%CI: 2.16 to 239.81, p= 0.009) were independent predictive factors for mortality. Discussion: Loss of consciousness and seizure were neurological manifestations served as independent predictive factors for mortality in COVID-19 patients. Keywords: COVID-19, loss of consciousness, mortality, neurological manifestations, seizure
HUBUNGAN POLIMORFISME MTHFR c.677C>T DENGAN FUNGSI KOGNITIF PADA PASIEN STROKE ISKEMIK AKUT DI RSUP DR. SARDJITO Haq, Arinal; Gofir, Abdul; Ar Rochmah, Mawaddah; Amelia Nur Vidyanti; Yogik Onky Silvana Wijaya, Yogik Onky Silvana Wijaya
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 40 No 2 (2024): Vol 40 No 2 (2024): Volume 40, No 2 - Maret 2024
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v40i2.511

Abstract

Introduction: Ischemic stroke is an acute cerebrovascular event with cognitive impairment presents as its prevalent manifestation and complication. Methylenetetrahydrofolate reductase (MTHFR) is an important enzyme in folate metabolism through an integral process of cellular metabolism in DNA, RNA and protein methylation. MTHFR c.677C>T polymorphism is considered an important genetic risk factor for stroke and cognitive dysfunction in some populations. Aim: This study aimed to investigate the association between the MTHFR c.677C>T polymorphism and cognitive function in acute ischemic stroke patients in Dr. Sardjito General Hospital Yogyakarta. Methods: We performed a cross-sectional study in 42 consecutive acute ischemic stroke patients. PCR R-FLP was used to examine MTHFR c.677C>T polymorphism. Cognitive function was determined using MoCA-Ina within 24 hours of each patient’s admission, with score 24 is the cut off for cognitive impairment. Results: Of 42 patients, 12 patients (28.6%) showed MTHFR c.677C>T variant. There were 3 patients (25%) with homozygous variant of MTHFR c.677C>T. Cognitive dysfunction was found in 7 patients (16.7%) with MTHFR c.677C>T variant and 18 patients (42.9%) with wild type MTHFR. However, no significant association was found between MTHFR c.677C>T with cognitive function in acute ischemic stroke patients (p=0.921). Discussion: The frequency of MTHFR c.677C>T polymorphism in this study was 28.6% with a quarter of them showing homozygous variant. There was no association between MTHFR c.677C>T polymorphism with cognitive function in acute ischemic stroke patients.
SKOR RISIKO POLIGENIK, STATUS APOE, DAN TERAPI DENGAN TARGET AMILOID PADA PENYAKIT ALZHEIMER Vidyanti, Amelia Nur; Rahman, Rifki Habibi; Astuti
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 5: Edisi Suplemen Neurona Bekerjasama dengan JogjaCLAN 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i5.860

Abstract

Co-Authors Abdul Gofir Abdullah Syafiq Edyanto Anton Darmawan Astuti Cempaka Thursina Srie Setyaningrum Desin Pambudi Sejahtera Haq, Arinal Hiztien Fahrurriza Luthffia, Audiza Mawaddah Ar-Rochmah Nalendra Tama, Whisnu Nathania, Caroline Evanthe Pambudi Sejahtera, Desin Prodjohardjono, Astuti Rahman, Rifki Habibi Satiti, Sekar Setyaningrum, Cempaka Thursina Srie Setyaningsih, Indarwati Sri Sutarni Susianti, Noor Alia Yogik Onky Silvana Wijaya Yudhanto Utomo Yuli Firlando, Afdhal