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All Journal JURNAL ANALIS LABORATORIUM MEDIK Jurnal Ilmiah Kesehatan Masyarakat
Nazula Rahma Shafriani
Universitas ‘Aisyiyah Yogyakarta
Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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GAMBARAN HASIL GENEXPERT PADA PASIEN SUSPEK TUBERKLOSIS DI PUSKESMAS SEWON 1 TAHUN 2025 Oktaviani K. Tamau; Anggrieni Wisni; Nazula Rahma Shafriani
Jurnal Analis Laboratorium Medik Vol 11 No 1 (2026): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jalm.v11i1.6292

Abstract

Latar belakang: Tuberkulosis masih menjadi masalah kesehatan masyarakat di Indonesia. Pemeriksaan GeneXpert merupakan metode diagnostik berbasis molekuler yang digunakan untuk mendeteksi Mycobacterium tuberculosis dan resistensi rifampisin secara cepat dan akurat Tujuan: Mengetahui Gambaran Hasil GeneXpert Pada Pasien Suspek Tuberkulosis di Puskesmas Sewon 1 Tahun 2025 Metode: Deskriptif kuantitatif dengan pendekatan retrospektif menggunakan data sekunder hasil pemeriksaan GeneXpert periode Januari–Desember 2025. Teknik sampling menggunakan total sampling dengan jumlah sampel sebanyak 783 pasien. Analisis data dilakukan secara deskriptif menggunakan distribusi frekuensi dan persentase. Hasil: Dari 783 pasien yang menjalani pemeriksaan GeneXpert, sebanyak 726 pasien (92,7%) menunjukkan hasil MTB not detected dan 57 pasien (7,3%) MTB detected. Tingkat deteksi MTB terbanyak berada pada kategori very low (33,3%). Sebagian besar pasien MTB detected memiliki status rifampisin sensitif (89,5%). Usia terbanyak yaitu 55–64 tahun, berjenis kelamin laki-laki, dan berasal dari wilayah Timbulharjo. Kesimpulan: Hasil pemeriksaan GeneXpert pada pasien suspek Tuberkulosis di Puskesmas Sewon 1 Tahun 2025 didominasi oleh MTB not detected. Pasien MTB detected umumnya menunjukkan rifampisin sensitif, kategori deteksi very low, berusia 55–64 tahun, berjenis kelamin laki-laki, dan berasal dari Timbulharjo.
Gambaran Kadar TSH, FT3 dan FT4 pada Pasien Gangguan Tiroid di RSUD Anutaloko Parigi Khafifa Usnul Mar’iyah Dg Tompo; Nazula Rahma Shafriani; Farida Noor Irfani
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6023

Abstract

Thyroid disorders are a problematic condition in individuals due to dysfunction of the thyroid gland, such as changes in its form and function. The most common thyroid disorders include hyperthyroidism and hypothyroidism. This study aims to identify and analyze TSH, FT3, and FT4 levels in individuals diagnosed with thyroid disorders. This research uses a cross-sectional method by collecting secondary data. Secondary data for this research was obtained from records of TSH, FT3 and FT4 hormone examinations in the laboratory at Anutaloko Parigi Regional Hospital. This data covers the period January to December 2024, then processed and analyzed using descriptive statistical tests in SPSS, then presented in table format. Based on age characteristics, the majority of respondents with thyroid disorders were aged 25-59 years with a percentage of 25 people with hyperthyroidism and 11 people with hypothyroidism. Respondents with the most thyroid disorders were diagnosed with hyperthyroidism rather than hypothyroidism. The total number of patients who had TSH, FT3 and FT4 checked at Anutaloko Parigi Regional Hospital found that patients with hyperthyroidism were predominantly female and aged 25-59 years.
Gambaran Jumlah Hitung Jenis Leukosit pada Penderita Hepatitis B di Salah Satu Rumah Sakit Yogyakarta Citra Agung Hiola; Nazula Rahma Shafriani; Arif Bimantara
SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat Vol. 4 No. 3 (2025): Juli 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/sehatmas.v4i3.6037

Abstract

Hepatitis B is a serious infectious disease that can cause progressive liver damage and affect the body's immune system. This study aims to describe the profile of leukocyte counts and types in Hepatitis B patients as an indicator of the body's immune response. The study was conducted as an observational study using a descriptive quantitative approach and a cross-sectional design on 70 medical records of patients at a hospital in Yogyakarta from January to December 2024. The analysis results showed that the most commonly increased leukocyte types were neutrophils (47.1%) and monocytes (10%), while lymphocytes (50%) and eosinophils (34.3%) were most frequently decreased. Basophils were mostly within normal limits (98.6%). These findings indicate the activation of the innate immune system through neutrophilia, as well as a decrease in the adaptive immune system due to lymphocytopenia. These results highlight the importance of hematological examinations as an additional parameter in assessing the infection phase and immune response of Hepatitis B patients. Leukocyte examinations can also serve as a basis for clinical decision-making, particularly in monitoring therapy and disease progression.
Co-Authors Anggrieni Wisni Arif Bimantara Citra Agung Hiola Farida Noor Irfani Khafifa Usnul Mar’iyah Dg Tompo Oktaviani K. Tamau