Safira Nafisa
Faculty of Pharmacy, Universitas Pancasila, South Jakarta, Jakarta

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The nanoparticle formula optimization from Temulawak extract (Curcuma xanthorrhiza) as adjuvant therapy Greesty Finotory Swandiny; Safira Nafisa; Rahmatul Qodriah; Gumilar Adhi Nugroho; Muhammad Taher Bakhtiar
Interdisciplinary Social Studies Vol. 3 No. 2 (2024): January-March 2024 (Regular Issue)
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v3i2.629

Abstract

Temulawak extract was synthesized using temulawak sodium alginate. The nanoparticle formula was obtained by combining the characteristics of temuwak extract and temusawak. The microbeads were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The size of Alg-Curcuma was measured at SEM. The particle size distribution of the sample was analyzed using FTIR spectra. The results showed that the size of the resulting beads is microparticle in size. It was found that the temurawak extract is a good candidate as an anticancer agent. Therefore, there are several recommendations that can be done to optimize the synthesis of the material. The study reported that the recommended parameter is 12.5 kV with a flow rate of 0.1 mL/h (first batch synthesis).