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All Journal Jurnal Abdimas BSI: Jurnal Pengabdian Kepada Masyarakat Interdisciplinary Social Studies Abdi Implementasi Pancasila: Jurnal Pengabdian kepada Masyarakat Jurnal Janata Sciences of Phytochemistry Journal of Natural Product for Degenerative Diseases
Gumilar Adhi Nugroho
Faculty Of Pharmacy, Universitas Pancasila, South Jakarta, Jakarta
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Transportation

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EDUKASI DAN PENDAMPINGAN SERTIFIKASI HALAL SELF DECLARE PRODUK PANGAN SEHAT UMK RW 19 KELURAHAN CILANGKAP Yati Sumiyati; Esti Mulatsari; Nathalia Perdhanti Soemantri; Novi Yantih; Gumilar Adhi N Nugroho; Fauzia Noprima Okta; Trisna Permadi; Arfin Ahsanul Ihsan; Zahra Afifah; Anggiyasari Anggiyasari
Abdi Implementasi Pancasila:Jurnal Pengabdian kepada Masyarakat Vol 2 No 2 (2022): November
Publisher : Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.255 KB) | DOI: 10.35814/abdi.v2i2.4274

Abstract

Pembangunan nasional berkelanjutan terus dilakukan pemerintah untuk meningkatkan kesejahteraan masyarakat. Pemberdayaan Kesejahteraan Keluarga (PKK) merupakan organisasi kemasyarakatan yang memberdayakan wanita untuk turut berpartisipasi dalam pembangunan Indonesia. Organisasi ini dimotori oleh ibu-ibu rumah tangga yang peduli terhadap kesejahteraan lingkungannya, berusaha mencurahkan waktu ditengah kesibukan mengurus keluarganya. PKK RW19 berlokasi di Perumahan Griya Telaga Permai, Kelurahan Cilangkap, Kecamatan Tapos, Kota Depok. Dalam menjalankan program kerjanya, PKK ini dibagi menjadi 3 kelompok kegiatan (Poktan) yaitu Posyandu, posbindu dan Usaha Peningkatan Pendapatan Keluarga Sejahtera (UPPKS). Pandemik Covid-19 memberikan implikasi ekomomi khususnya terhadap kesejahteraan Warga RW19. Jika dipandang dari sudut positif, pandemik menginisiasi tumbuhnya Usaha Mikro Kecil (UMK) di sektor pangan. Banyak ibu-ibu rumah tangga yang mulai berdagang makanan dengan tujuan membantu perekonomian keluarganya. Pelaku usaha umumnya masih memproduksi makanan secara konvensional berdasarkan pengalaman dengan menggunakan bahan-bahan yang ‘terjangkau’ untuk menekan harga. Terhadap permasalahan ini Tim PKM berencana memperkuat Kembali fungsi PKK RW19 dengan membangun high performance teams dan elaborasi untuk membina UMK agar dapat optimal membangun bisnisnya. Sementara permasalahan pada UMK terkait produk adalah minimalnya pengetahuan mengenai pangan fungsional yang berimplikasi terhadap imunitas tubuh dan berbagai peraturan pemerintah yang berkaitan dengan keamanan pangan serta jaminan produk yang thayyib. Di lain pihak, regulator memiliki keterbatasan sumber daya manusia dalam pengawasan dan pengendalian produk pangan yang beredar. UMK juga memiliki ketebatasan pemahaman mengenai brand image dan pemasaran produk. Solusi yang diberikan adalah memberikan edukasi, pelatihan, dan pendampingan mulai dari pangan sehat/fungsional, brand image, hingga pendampingan perolehan sertifikat halal (self-declare). Kegiatan yang dilakukan ini akan meningkatkan citra produk dan penjualan UMK yang akan meningkatkan kesejahteraan pelaku usaha dan warga sekitar.
PERBAIKAN EKSTRAKSI PRODUK HERBAL Arif Tatak; Yati Sumiyati; Rovida Camalia Hartantrie; Yesi Desmiaty; Gumilar Adhi Nugroho
Jurnal JANATA Vol 2 No 2 (2022): Jurnal Janata
Publisher : Program Studi Teknik Sipil Fakultas Teknik Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/janata.v2i2.4364

Abstract

Produk herbal yang dimanfaatkan untuk menjaga stamina dan pengobatan saat ini sudah diolah sehingga bisa diperoleh dalam sediaan serbuk yang dikemas sebagai kapsul, tablet atau sirup. Serbuk tersebut adalah hasil ekstraksi dari bahan herbal. Salah satu tahapan dalam proses ekstraksi herbal adalah proses pemasakan bahan herbal. Proses pemasakan ini memegang peranan sangat penting karena menentukan kualitas ekstrak herbal yang dihasilkan. Penggunaan panas berlebih (over heat) akan mengakibatkan rusaknya kandungan nutrisi yang ada pada bahan herbal. Untuk meminimalisasi terjadinya panas berlebih pada proses pemasakan maka digunakan panas dari uap air yang dihasilkan oleh boiler. Hal ini diharapkan dapat memperbaiki kualitas produk ekstrak herbal yang sebelumnya dimasak menggunakan kompor gas.
Edukasi Peningkatan Aspek Mutu Obat Tradisional bagi Pengguna dan Pelaku Usaha Obat Tradisional Desmiaty, Yesi; Nugroho, Gumilar Adhi; Okta, Fauzia Noprima; Sandhiutami, Ni Made Dwi; Sumiyati, Yati; Priyanti, Ike Ari
Jurnal Abdimas BSI: Jurnal Pengabdian Kepada Masyarakat Vol 6, No 2 (2023): Agustus 2023
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Bina Sarana Informatika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31294/jabdimas.v6i2.14627

Abstract

Adanya pandemi covid-19 membuat masyarakat berusaha lebih untuk menjaga kesehatan salah satunya dengan menggunakan obat herbal, sehingga terjadi peningkatan penggunaan obat herbal di Indonesia. Hal ini tentu harus diimbangi dengan mutu yang terjamin dari obat herbal di pasaran. Kegiatan pengabdian kepada masyarakat ini dalam rangka mengedukasi masyarakat sebagai pengguna obat herbal maupun pelaku usaha herbal agar memperhatikan aspek mutu obat herbal. Saat ini masih terdapat obat herbal yang beredar di masyarakat dan tidak memenuhi persyaratan. Metode edukasi dilakukan secara daring dengan menyebarkan kuisioner untuk mengetahui pengetahuan masyarakat, dilanjutkan dengan edukasi dan diskusi interaktif. Dari hasil survey menunjukkan responden umumnya belum terlalu memahami aspek mutu obat herbal sehingga perlu untuk dilakukan edukasi agar dapat memilih obat herbal yang bermutu baik serta bagi pelaku usaha herbal dapat meningkatkan mutu produknya sesuai dengan persyaratan yang diberlakukan oleh regulator yaitu Badan Pengawas Obat dan Makanan Republik Indonesia (BPOM RI).
The nanoparticle formula optimization from Temulawak extract (Curcuma xanthorrhiza) as adjuvant therapy Greesty Finotory Swandiny; Safira Nafisa; Rahmatul Qodriah; Gumilar Adhi Nugroho; Muhammad Taher Bakhtiar
Interdisciplinary Social Studies Vol. 3 No. 2 (2024): January-March 2024 (Regular Issue)
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/iss.v3i2.629

Abstract

Temulawak extract was synthesized using temulawak sodium alginate. The nanoparticle formula was obtained by combining the characteristics of temuwak extract and temusawak. The microbeads were characterized by scanning electron microscopy (SEM) and Fourier transform infrared (FTIR) spectroscopy. The size of Alg-Curcuma was measured at SEM. The particle size distribution of the sample was analyzed using FTIR spectra. The results showed that the size of the resulting beads is microparticle in size. It was found that the temurawak extract is a good candidate as an anticancer agent. Therefore, there are several recommendations that can be done to optimize the synthesis of the material. The study reported that the recommended parameter is 12.5 kV with a flow rate of 0.1 mL/h (first batch synthesis).
Phenolic Content and Antioxidant Activity of Colocasia esculenta in Commercial Herbal Products Nugroho, Gumilar Adhi; Desmiaty, Yesi; Sumiyati, Yati; Suherman, Sandra Loretta; Lim, Helsa
Sciences of Phytochemistry Volume 4 Issue 1
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphy0401288

Abstract

Taro (Colocasia esculenta L.) is a plant with a long history of use in traditional medicine in several countries worldwide. The corm of taro and two commercial products were analysed due to total phenolic, flavonoid, luteolin, and antioxidant properties. Taro corm was extracted with water and analysed for phytochemical screening, total flavonoids, total phenolic, luteolin, and antioxidant properties. The phytochemical screening of taro showed that it contains secondary metabolites of flavonoids, tannins, saponins, triterpenoids, and quinones. The results of the determination of total flavonoid content of taro extract, Product 1, and Product 2 capsule obtained 19.34 ± 0.26 mg QE/g extract, 18.58 ± 0.18 mg QE/g extract, and 16.29 ± 0.23 mg QE/g extract. The results of determining the total phenolic content of taro, Product 1, and Product 2 capsules obtained 39.75 ± 0.95 mg GAE/g extract, 38.46 ± 0.46 mg GAE/g extract, and 35.91 mg GAE/g extract. ± 0.82 mg GAE/g extract. The results of the determination of luteolin from taro, Product 1, and Product 2 capsules obtained 0.83 ± 0.05 %, 0.39 ± 0.04 %, and 0.18 ± 0.08 %. The results of the antioxidant activity test obtained IC50 of vitamin C of 4.6780 ± 0.0319 ppm, corm dry extract and ginger rhizome 141.2383 ± 3.4995 ppm and 97.6685 ± 7.8760 ppm, respectively, and capsule products 2; 126.0724± 1.3672 ppm. The water extract of corm and available products containing CE extract have met the quality standard parameters required for non-specific parameters, luteolin content, and antioxidant properties.
EDUKASI DAGUSIBU (DAPATKAN, GUNAKAN, SIMPAN, DAN BUANG) ANTIBIOTIK KEPADA MASYARAKAT SERANG Marwati, Umi; Okta, Fauzia Noprima; Nugroho, Gumilar Adhi; Larasinta, Nadia; Hakim, Zainur Rahman; Pratita, Rasta Naya; Sari, Intan Pertama; Faizatun, Faizatun; Jasmadeti, Jasmadeti
Abdi Implementasi Pancasila:Jurnal Pengabdian kepada Masyarakat Vol 5 No 1 (2025): Mei
Publisher : Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/ntmm1z26

Abstract

Infeksi Saluran Pernapasan Akut (ISPA) adalah penyakit infeksi yang disebakan oleh mikroorganiseme, salah satunya adalah bakteri. Penyakit ISPA berulang dapat menyebabkan pneumonia. Perlunya dicegah keberulangan penyakit dengan terapi yang efektif. Kegiatan PkM ini bertujuan untuk memberikan edukasi terkait topik penggunaan antibiotik yang tepat (DAGUSIBU) kepada masyarakat untuk meningkatkan efektivitas terapi dan mencegah resistensi antibiotik. Kegiatan pengabdian kepada masyarakat dilaksanakan secara hybrid (luring di kecamatan Cinangka dan daring di Fakultas Farmasi Universitas Pancasila (FFUP). Tingkat pemahaman peserta diukur menggunakan kuisioner yang diberikan sebelum dan setelah penyuluhan. Dari sepuluh indikator masalah yang digali, terdapat tiga indikator yang memiliki nilai terendah sebelum diberikan edukasi, yaitu pengetahuan responden terkait logo antibiotik, pengertian resistensi, dan cara membuang antibiotik. Ketiga indikator ini mengalami peningkatan setelah diberikan edukasi
PEMANFAATAN KECOMBRANG (ETLINGERA ELATIOR) SEBAGAI MINUMAN KESEHATAN TRADISIONAL DI DESA PUTAT NUTUG Nugroho, Gumilar Adhi; Faizatun; Marwati, Umi; Pratita, Rasta naya; Kurniawan, Fajar Ary
Jurnal JANATA Vol. 5 No. 1 (2025): Jurnal Janata
Publisher : Program Studi Teknik Sipil Fakultas Teknik Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/41zm5871

Abstract

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan warga Desa Putat Nutug, Kecamatan Ciseeng, Kabupaten Bogor, mengenai pemanfaatan tanaman kecombrang (Etlingera elatior) sebagai minuman kesehatan. Kegiatan dilakukan melalui penyuluhan, pelatihan, serta evaluasi pre dan posttest. Hasil menunjukkan adanya peningkatan pengetahuan dan keterampilan peserta pada tiga aspek utama: pengenalan tanaman kecombrang, manfaat kesehatan, dan teknik pengolahan. Peningkatan nilai rata-rata dan penurunan standar deviasi pada beberapa aspek mengindikasikan efektivitas metode edukatif yang diterapkan. Kegiatan ini diharapkan menjadi pemicu lahirnya usaha lokal berbasis produk alam serta meningkatkan kesadaran masyarakat terhadap potensi tanaman lokal.
Development, Optimization, and Characterization of Wet-Granulated Curcumin Nanostructured Lipid Carrier Tablets Mantika Atiqah Baihaty; Gumilar Adhi Nugroho; Deni Rahmat; Faridah
Journal of Natural Product for Degenerative Diseases Vol. 3 No. 1 (2025): JNPDD September
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/v3i1.9214

Abstract

Curcumin has been widely recognized for its broad therapeutic potential, including its emerging role as an antiviral agent. However, its clinical translation is limited by poor aqueous solubility, rapid metabolism, and low oral bioavailability. To address these challenges, nanostructured lipid carriers (NLCs) have been proposed as a promising delivery system to enhance curcumin stability and systemic availability. This study aimed to formulate curcumin-loaded NLCs, optimize their physicochemical characteristics, and develop an oral tablet dosage form using the wet granulation method with super-disintegrant variation. The optimized NLC formulation was prepared and subsequently freeze-dried prior to compression into tablets. Particle size, polydispersity index (PDI), zeta potential, morphology, entrapment efficiency (EE), and loading capacity (LC) were evaluated. Tablets were formulated using starch, croscarmellose sodium (2% and 3%), PVP, aerosil, and Avicel PH 102, followed by assessment of physical quality parameters including weight uniformity, hardness, friability, disintegration, and dissolution profile. The optimized NLCs exhibited desirable nanoscale characteristics, with particle size of 70.95 nm, PDI 0.379, zeta potential −23.9 mV, spherical morphology, EE 99.75%, and LC 9.93%. The resulting tablets were yellow, bitter, and odorless, with acceptable pharmacopeial quality. Weight and size uniformity were within limits, hardness was 3.81 kg/cm² and 4.38 kg/cm², friability 1.45% and 0.50%, and disintegration times 1.86 min and 1.28 min for 2% and 3% super-disintegrant, respectively. Dissolution profiles indicated 26.12% and 25.79% release within the test period. Curcumin can be successfully formulated into stable NLCs with excellent encapsulation efficiency and incorporated into wet-granulated tablets meeting pharmacopeial standards. The use of 3% croscarmellose sodium provided the most favorable disintegration profile, suggesting its potential as an optimized oral dosage form to improve curcumin delivery and bioavailability.
Pharmacognostic and Phytochemical Characterization of Colocasia esculenta var. antiquorum Corm (Araceae) and Preliminary Evaluation of Its Antimicrobial Activity Sumiyati, Yati; Yesi Desmiaty; Gumilar Adhi Nugroho; Fauzia Noprima Okta
Journal of Natural Product for Degenerative Diseases Vol. 3 No. 1 (2025): JNPDD September
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/v3i1.9218

Abstract

Colocasia esculenta has been reported in reputable journals to exhibit various bioactivities, including antioxidant, anti-inflammatory, and antidiabetic properties. This study aimed to investigate the pharmacognostic characteristics and phytochemical profile of Colocasia esculenta var. antiquorum corm (Araceae). The corms were collected, authenticated, oven-dried, and subjected to preliminary pharmacognostic and phytochemical analyses. Pharmacognostic evaluations included organoleptic, microscopic, and physicochemical examinations. The dried corm powder was extracted with distilled water, followed by qualitative phytochemical screening. The extract was found to contain saponins, flavonoids, tannins, and triterpenoids. Antimicrobial activity was further evaluated against Staphylococcus aureus, Escherichia coli, and Candida albicans, which were selected as representative pathogenic microorganisms for Gram-positive bacteria, Gram-negative bacteria, and fungi, respectively. These microorganisms were chosen based on previous reports demonstrating that the ethanolic leaf extract of taro exhibited antifungal activity against Candida albicans and antibacterial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella, and Escherichia coli. However, no inhibitory effect was observed in this study. All analyses were performed in accordance with the guidelines of the Indonesian Herbal Pharmacopeia. The findings provide reference data for the pharmacognostic identification of Colocasia esculenta corm and highlight its phytochemical constituents. Further investigations on other biological activities are required to validate its therapeutic potential. 
Enhanced Efficacy of Kaffir Lime (Citrus hystrix) Essential Oil Spray Gel Against Aedes aegypti Mosquitoes Nugroho, Gumilar Adhi; Desmiaty, Yesi; Fahleni, Fahleni; Lhu Muslimah, Lhu; Andam Dewi, Mira
Journal of Natural Product for Degenerative Diseases Vol. 1 No. 1 (2023): JNPDD September
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v1i1.5469

Abstract

The primary mode of dengue disease transmission is by the Aedes aegypti mosquito. The essential oil derived from Kaffir lime (Citrus hystrix) leaves comprises 66.85% beta-citronellal, 6.59% beta-citronellol, 3.90% linalol, and 1.76% citronellol. These constituents exhibit repelling properties. The objective of this study was to develop a spray gel formulation using kaffir lime leaf essential oil to create an efficient repellent. The process involves tearing fresh kaffir lime leaves and subsequently distilling them with distilled water. The distillation procedure yields an essential oil that is subsequently incorporated into a spray gel formulation, with varying concentrations of 1%, 5%, and 10%. Based on the findings of the efficacy test from 3 spray gel formulas through mosquito repelling activity conducted over 6 hours, it can be concluded that all tested formulas exhibited variation in effectiveness in repelling mosquito bites. The efficacy of the protection index against Aedes aegypti mosquito bites is contingent upon the concentration of kaffir lime essential oil in the formulation. There is a positive correlation between concentration and the duration of protection.
Co-Authors Andam Dewi, Mira Anggiyasari Anggiyasari Arfin Ahsanul Ihsan Arif Tatak Camalia Hartantrie, Rovida Deni Rahmat Fahleni Fahleni Faizatun FAIZATUN, FAIZATUN FARIDAH Fauzia Noprima Okta Fauzia Noprima Okta Greesty Finotory Swandiny Hakim, Zainur Rahman Jasmadeti, Jasmadeti Kurniawan, Fajar Ary Larasinta, Nadia Lhu Muslimah, Lhu Lim, Helsa Mantika Atiqah Baihaty Marwati, Umi Muhammad Taher Bakhtiar Mulatsari, Esti Nathalia Perdhani Soemantri Ni Made Dwi Sandhiutami Noviyantih, Noviyantih Okta, Fauzia Noprima Partomuan Simanjuntak Pratita, Rasta Naya Priyanti, Ike Ari Qodriah, Rahmatul Safira Nafisa Sari, Intan Pertama Shirly Kumala Suherman, Sandra Loretta Trisna Permadi YATI SUMIYATI Yati Sumiyati, Yati Yesi Desmiaty, Yesi Zahra Afifah