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All Journal Berkala Kedokteran Indonesian Journal of Case Reports
Salan, Yosef Dwi Cahyadi
Fakultas Kedokteran Universitas Lambung Mangkurat
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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BIOMARKER TERKINI DALAM USAHA MEMPREDIKSI PREEKLAMPSIA Salan, Yosef Dwi Cahyadi
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i1.3448

Abstract

Abstract: Preeclampsia is a life-threatening disease and can occur in all pregnant women. Preeclampsia was defined as a disease in pregnant women that is characterized by an increase in blood pressure exceeds 140 mmHg for systolic and 90 mmHg for diastolic that occured in pregnant women with gestational age above 20 weeks. In recent decades the incidence of preeclampsia continues to rise and is caused by various factors. Factors to be considered as the most influential is the process of the growth of the placenta which is abnormal, but the main factors that trigger the growth of the placenta become abnormal is not yet certainly known, some studies tryingto find out the various factors that can trigger the growth of abnormal placentation of preeclampsia, especially the associationof the growth pattern blood vessels in the placenta are thought to have a major role in the occurrence of preeclampsia in pregnant women. From these studies are found several biomarkers that are believed to be an early marker in an attempt to prevent the occurrence of preeclampsia in pregnant women, such as angiogenic markers, immunological markers, markers of Metabolic and Endocrine marker. Keywords: Preeclampsia, Abnormal Placentation, and Early Biomarker. Abstrak: Preeklampsia merupakan salah satu penyakit yang mengancam jiwa dan dapat terjadi pada semua ibu hamil. Preeklampsia didefinisikan sebagai suatu penyakit pada ibu hamil yang ditandai dengan adanya peningkatan tekanan darah melebihi 140 mmHg untuk sistolik dan 90 mmHg untuk diastolik yang terjadi pada ibu hamil dengan usia kehamilan diatas 20 minggu. Dalam beberapa dekade terakhir angka kejadian preeklampsia terus meningkat dan disebabkan oleh berbagai macam faktor. Faktor yang dianggap paling berpengaruh yaitu adanya proses pertumbuhan plasenta yang tidak normal, akan tetapi faktor utama yang mencetuskan terjadinya pertumbuhan plasenta secara abnormal tersebut belum diketahui dengan pasti, beberapa penelitian mencoba mencari tau berbagai faktor yang dapat memicu terjadinya pertumbuhan plasenta abnormal pada preeklampsia, terutama yang berhubungan dengan pola pertumbuhan pembuluh darah pada plasenta yang diduga memiliki peranan besar dalam terjadinya preeklampsia pada ibu hamil. Dari penelitian-penelitian tersebut didapatkan beberapa biomarker yang dipercaya dapat menjadi penanda dini dalam usaha untuk mencegah terjadinya preeklampsia pada ibu hamil, seperti marker Angiogenik, marker Immunologis, marker Metabolik, dan marker Endokrin. Kata-kata Kunci: Preeklampsia, Pertumbuhan Plasenta Abnormal, dan Biomarker  Penanda Dini. 
EFFECT OF LENGTH OF PREMATURE RUPTURE OF MEMBRANES PERIOD TOWARD APGAR SCORE OF THE INFANT AND MATERNAL LEUKOCYTE SERUM IN ULIN GENERAL HOSPITAL BANJARMASIN Salan, Yosef Dwi Cahyadi
Berkala Kedokteran Vol 13, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v13i2.4076

Abstract

Abstract: Premature rupture of membranes (PROM) is a condition of rupture of membranes before the birth takes place. The incidence of PROM varies from 3% to 10% of all births and complicates more than 3% of pregnancies with PROM. The purpose of this study was to determine the relationship between the length of the PROM period toward the APGAR score of the infant and maternal leukocyte serum. The research design was analytic observational with retrospective cohort approach. From the result we found a correlation between PROM period with outcome of infant’s APGAR score, there were a total of 89 samples fulfilling the inclusion criteria, with 57 samples of PROM<12 hours (51 with good APGAR score and 6 with bad APGAR score) and 32 samples PROM> 12 hours (16 with good APGAR score, and 16 with bad APGAR score). From the result of the correlation of leukocyte level with the length of PROM period was found total of 84 samples fulfilling the inclusion criteria, with 54 samples of PROM<12 hours (53 with normal leukocyte score and 1 with leukocytosis score) and 30 samples PROM> 12 hours (28 with normal leukocyte score, and 2 with leukocytosis score). From the analysis results we obtained a strong relationship between the length of PROM period with the infant’s APGAR (P = 0.0001, OR 8.5), whereas in the relationship between the length of PROM period with maternal blood leukocyte level there is no significant relationship (p= 0,599).  Keywords: Premature Rupture of Membranes, APGAR, Leukocyte Serum
BIOMARKER TERKINI DALAM USAHA MEMPREDIKSI PREEKLAMPSIA Yosef Dwi Cahyadi Salan
Berkala Kedokteran Vol 13, No 1 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (511.757 KB) | DOI: 10.20527/jbk.v13i1.3448

Abstract

Abstract: Preeclampsia is a life-threatening disease and can occur in all pregnant women. Preeclampsia was defined as a disease in pregnant women that is characterized by an increase in blood pressure exceeds 140 mmHg for systolic and 90 mmHg for diastolic that occured in pregnant women with gestational age above 20 weeks. In recent decades the incidence of preeclampsia continues to rise and is caused by various factors. Factors to be considered as the most influential is the process of the growth of the placenta which is abnormal, but the main factors that trigger the growth of the placenta become abnormal is not yet certainly known, some studies tryingto find out the various factors that can trigger the growth of abnormal placentation of preeclampsia, especially the associationof the growth pattern blood vessels in the placenta are thought to have a major role in the occurrence of preeclampsia in pregnant women. From these studies are found several biomarkers that are believed to be an early marker in an attempt to prevent the occurrence of preeclampsia in pregnant women, such as angiogenic markers, immunological markers, markers of Metabolic and Endocrine marker. Keywords: Preeclampsia, Abnormal Placentation, and Early Biomarker. Abstrak: Preeklampsia merupakan salah satu penyakit yang mengancam jiwa dan dapat terjadi pada semua ibu hamil. Preeklampsia didefinisikan sebagai suatu penyakit pada ibu hamil yang ditandai dengan adanya peningkatan tekanan darah melebihi 140 mmHg untuk sistolik dan 90 mmHg untuk diastolik yang terjadi pada ibu hamil dengan usia kehamilan diatas 20 minggu. Dalam beberapa dekade terakhir angka kejadian preeklampsia terus meningkat dan disebabkan oleh berbagai macam faktor. Faktor yang dianggap paling berpengaruh yaitu adanya proses pertumbuhan plasenta yang tidak normal, akan tetapi faktor utama yang mencetuskan terjadinya pertumbuhan plasenta secara abnormal tersebut belum diketahui dengan pasti, beberapa penelitian mencoba mencari tau berbagai faktor yang dapat memicu terjadinya pertumbuhan plasenta abnormal pada preeklampsia, terutama yang berhubungan dengan pola pertumbuhan pembuluh darah pada plasenta yang diduga memiliki peranan besar dalam terjadinya preeklampsia pada ibu hamil. Dari penelitian-penelitian tersebut didapatkan beberapa biomarker yang dipercaya dapat menjadi penanda dini dalam usaha untuk mencegah terjadinya preeklampsia pada ibu hamil, seperti marker Angiogenik, marker Immunologis, marker Metabolik, dan marker Endokrin. Kata-kata Kunci: Preeklampsia, Pertumbuhan Plasenta Abnormal, dan Biomarker  Penanda Dini. 
EFFECT OF LENGTH OF PREMATURE RUPTURE OF MEMBRANES PERIOD TOWARD APGAR SCORE OF THE INFANT AND MATERNAL LEUKOCYTE SERUM IN ULIN GENERAL HOSPITAL BANJARMASIN Yosef Dwi Cahyadi Salan
Berkala Kedokteran Vol 13, No 2 (2017)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (367.355 KB) | DOI: 10.20527/jbk.v13i2.4076

Abstract

Abstract: Premature rupture of membranes (PROM) is a condition of rupture of membranes before the birth takes place. The incidence of PROM varies from 3% to 10% of all births and complicates more than 3% of pregnancies with PROM. The purpose of this study was to determine the relationship between the length of the PROM period toward the APGAR score of the infant and maternal leukocyte serum. The research design was analytic observational with retrospective cohort approach. From the result we found a correlation between PROM period with outcome of infant’s APGAR score, there were a total of 89 samples fulfilling the inclusion criteria, with 57 samples of PROM<12 hours (51 with good APGAR score and 6 with bad APGAR score) and 32 samples PROM> 12 hours (16 with good APGAR score, and 16 with bad APGAR score). From the result of the correlation of leukocyte level with the length of PROM period was found total of 84 samples fulfilling the inclusion criteria, with 54 samples of PROM<12 hours (53 with normal leukocyte score and 1 with leukocytosis score) and 30 samples PROM> 12 hours (28 with normal leukocyte score, and 2 with leukocytosis score). From the analysis results we obtained a strong relationship between the length of PROM period with the infant’s APGAR (P = 0.0001, OR 8.5), whereas in the relationship between the length of PROM period with maternal blood leukocyte level there is no significant relationship (p= 0,599).  Keywords: Premature Rupture of Membranes, APGAR, Leukocyte Serum
Hope After Cancer: Pregnancy Outcomes Following Fertility-Sparing Surgery – A Case Report Marpaung, Richardo; Armanza, Ferry; Yuseran, Hariadi; Waluyo, Setyo Teguh; Salan, Yosef Dwi Cahyadi
Indonesian Journal of Case Reports Vol. 3 No. 1 (2025): June 2025
Publisher : Heca Sentra Analitika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.60084/ijcr.v3i1.260

Abstract

Pregnancy after diagnosis of ovarian cancer is a rare event. Ovarian Cancer is associated with difficulty in achieving pregnancy. Little is known about the mechanism of this condition due to limited literature and studies. In this paper, the authors report a rare case of successful pregnancy in a patient with ovarian cancer. Patient initially diagnosed with cystadenocarcinoma mucinous of the ovary, two years prior to pregnancy, and later diagnosed with suspected ovarian cancer in the third trimester. The patient was then treated with optimal debulking surgery and cesarean section at 35 weeks of pregnancy. The patient delivered a healthy baby girl. Debulking surgery was carried out, and the patient was scheduled for chemotherapy. The findings from this case conclude that patients with ovarian cancer who receive conservative surgical treatment could have successful pregnancy outcomes. The quality of the patient’s life should be a priority, and follow-up for further treatment is essential.
Co-Authors Ferry Armanza, Ferry Marpaung, Richardo Waluyo, Setyo Teguh Yuseran, Hariadi