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Hubungan Karakteristik Individu dan Sanitasi Lingkungan Terhadap Keberhasilan Pengobatan Tuberculosis di RSUD Bengkalis Ikhwan Resmala Sudji; Solehan Solehan; Dewi Yudiana Shinta; M Diki Juliandi
Jurnal Zona Vol 8, No 1 (2024)
Publisher : Pelantar Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52364/zona.v8i1.112

Abstract

Mycobacterium tuberculosis is a pathogenic bacterium that is the causative agent of tuberculosis. The treatment of tuberculosis is a lengthy process that may induce boredom and lead to the cessation of medication in patients, which can result in the development of bacterial resistance to multiple anti-tuberculosis drugs. Many factors affected the success of tuberculosis treatment include individual characteristics such as age, education, occupation, and environmental conditions such as occupancy density, ventilation, lighting and floor condition. The objective of the study was to know correlation between individual characteristic and home environment with the success of tuberculosis treatment. The observational retrospective and analytics design were applied, which the research population were 30 individual tuberculosis patients who have been regularly without stop taking antibiotics for 6 months or more at the Bengkalis District Hospital. The results demonstrated that all participant have taken tuberculosis antibiotics drugs for more than 6 months and GeneXpert results confirmed 2 patients (6,7%) exhibited positive results for Mycobacterium tuberculosis, and 28 patients (93,3%) exhibited negative results. The individual characteristic such as education level, occupation and enveromental sanitation related to unsuccessful tuberculosis treatment. The findings of this study indicate a need for further examination of the presence of Mycobacterium tuberculosis in patients who have completed treatment, with the objective of ensuring the absence of Mycobacterium tuberculosis in the patient's body.
Studi Kesehatan Lingkungan Terhadap Penderita Tuberkulosis Paru yang Mengkonsumsi Obat Anti Tuberkulosis (OAT) Dewi Yudiana Shinta; Muhammad Diki Juliandi; Melly Siska Suryani; Ikhwan Resmala Sudji; Merry Thressia; Herix Sonata MS
SEHATI: Jurnal Kesehatan Vol 5, No 2 (2025)
Publisher : Pelantar Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52364/sehati.v5i2.121

Abstract

Pulmonary tuberculosis (TB) is an infectious disease that requires long-term treatment using anti-tuberculosis drugs (OAT). The use of OAT, especially in the long term, can cause side effects on metabolism and organ function, one of which is indicated by changes in uric acid and urea levels in the blood. This study aims to analyze the relationship between environmental health and uric acid and urea levels in pulmonary TB patients undergoing OAT therapy. The benefits of this research include examining the relationship between uric acid and urea levels in pulmonary TB patients taking anti-tuberculosis drugs (OAT) and informing patients that TB treatment may cause an increase in uric acid and urea levels in the kidneys. The study design is an analytical observational study. The cross-sectional design involves measuring uric acid and urea levels using a chemical analyzer. The results of uric acid level measurements using the chemical analyzer showed that 25 respondents had normal uric acid levels (72%), while 28% had levels above the normal range. For urea levels, 16 respondents (64%) had normal values, and 9 respondents (36%) had levels exceeding the normal range. After consuming OAT for 1 month or less, 9 patients (60%) were observed, 2–3 months for 2 patients (13.33%), and 5 months for 1 patient (6.67%).