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PENGARUH EKSTRAK BIJI KOPI HIJAU ROBUSTA, ARABIKA DAN LIBERIKA TERHADAP HISTOPATOLOGI PANKREAS PADA MENCIT DIABETES: THE EFFECT OF ROBUSTA, ARABICA, AND LIBERICA GREEN COFFEE BEAN EXTRACT ON HISTOPATHOLOGY OF THE PANCREAS IN DIABETIC MICE Fenny Khairunnisa; Almahdy A; Armenia
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 7 No 3 (2022)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v7i3.391

Abstract

Biji kopi hijau memiliki kandungan asam klorogenat berpotensi sebagai anti diabetes. Penelitian ini bertujuan mengetahui efek perlindungan terhadap kerusakan pankreas mencit yang diinduksi aloksan. Hewan uji mencit sebanyak 45 ekor dibagi secara acak menjadi lima kelompok yaitu kelompok I kontrol negatif diberikan aquadest, kelompok II sebagai kontrol positif diberikan suspensi glibenklamid, kelompok III, IV dan V diberikan ekstrak air biji kopi hijau robusta, arabika dan liberika berturut-turut. Perlakuan diberikan setiap hari selama 14 hari per oral. Data dianalisis dengan ANOVA dua arah diikuti uji lanjut Duncan. Hasil penelitian menunjukkan ekstrak air biji kopi hijau memberikan perbedaan yang nyata (P<0,05) terhadap skor histopatologi pankreas. Ekstrak air biji kopi hijau robusta memberikan gambaran histopatologi yang paling baik dibandingkan arabika dan liberika. Berdasarkan hasil penelitian ini, disimpulkan bahwa ekstrak air biji kopi hijau berpotensi sebagai pengobatan alternatif anti diabetes.
A Literature Review On the Formulation, Characterization, and Stability of Cinnamomum burmannii Emulgel Extract as an Antioxidant and Sunscreen Rodhia Ulfa; Ferdy Firmansyah; Fenny Khairunnisa; Putri Lestari
Jurnal Ilmu Farmasi dan Farmasi Klinik Vol 21, No 1 (2024): Jurnal Ilmu Farmasi & Farmasi Klinik
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v21i1.9126

Abstract

Emulgel is a pharmaceutical formulation that integrates the characteristics of both emulsions and gels, resulting in a semisolid product. The utilization of emulgel formulations has been shown to enhance the efficacy of drug delivery by facilitating deeper skin penetration and subsequently augmenting its pharmacological activity. The antioxidant and sunscreen properties of cinnamon bark extract make it suitable for incorporation into an emulgel formulation. Variations in the concentration of extracts and gelling agents can have an impact on the physical properties, stability, and pharmacological efficacy of the emulgel. The objective of this review is to ascertain the optimal concentrations of extracts and gelling agents in emulgel formulations for enhanced efficacy. The employed methodology entails conducting a comprehensive review of scholarly articles pertaining to emulgel formulations containing cinnamon bark extract. These formulations encompass a range of concentrations of both the extract itself and gelling agents, while also possessing antioxidant and sunscreen properties. The formulation that is recommended is one that satisfies the criteria pertaining to its physical attributes, stability, and pharmacological efficacy. The emulgel formulation that best meets the specified criteria consists of a 1% concentration of cinnamon bark extract in combination with the gelling agent Viscolam MAC 5%.
ARTIKEL REVIEW: POTENSI BUAH BIT (Beta vulgaris L.) SEBAGAI BAHAN PEWARNA ALAMI DALAM FORMULASI LIP TINT Khairunnisa, Fenny; Hasibuan, Elmi Sariani; Ismirza, Ulfa
Ensiklopedia of Journal Vol 7, No 4 (2025): Vol. 7 No. 4 Edisi 2 Juli 2025
Publisher : Lembaga Penelitian dan Penerbitan Hasil Penelitian Ensiklopedia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33559/eoj.v7i4.3323

Abstract

Abstract: In recent years, the increasing demand for natural cosmetics has driven research into plant-based dyes as an alternative to synthetic materials. One promising source of natural dyes is beetroot (Beta vulgaris L.) which contains betacyanin pigment compounds. This review article aims to review various literatures related to the potential, benefits, and challenges of using beetroot as a natural dye in lip tint formulations. Based on a review of various studies, beetroot extracts show antioxidant activity, intense coloring, and are safe for the skin. However, constraints such as color stability to light and pH are still challenges in its application in the cosmetics industry.Keywords: Beta vulgaris L, betacyanin, beetroot, lip tint.