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CORRELATION OF NEUTROPHIL LYMPHOCYTE RATIO WITH HbA1C IN DIABETIC ULCERS Ni Nengah Dwi Putri Meili Wahyuni; Ersandhi Resnhaleksmana; Fihiruddin Fihiruddin
Meditory : The Journal of Medical Laboratory Vol. 14 No. 1 (2026): Meditory, Volume 14 No. 1 Tahun 2026
Publisher : Jurusan Teknologi Laboratorium Medis, Poltekkes Kemenkes Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33992/meditory.v14i1.4104

Abstract

Background: Patients diagnosed with diabetes are susceptible to complications, including diabetic ulcers. HbA1C is one of the key parameters used to evaluate glycemic control At the same time, the neutrophil-to-lymphocyte ratio (NLR) is a test used to detect inflammatory processes in patients with diabetes mellitus who develop diabetic ulcers. Objective: This research analyzes the relationship between the neutrophil-to-lymphocyte ratio (NLR) and HbA1C levels in patients with diabetes mellitus and diabetic foot ulcers. Methods: The research has a cross-sectional design. Data were collected retrospectively using non-probability sampling through a purposive sampling method from January 2024 to January 2025. Data were obtained from 83 individuals diagnosed with diabetes mellitus, including those with diabetic ulcer. Results: The highest NLR value was 26.47 and the lowest was 1.14. The highest HbA1C value was 51.0, while the lowest was 5.40. Spearman's statistical test indicated no significant correlation between NLR and HbA1C in patients with diabetes mellitus and diabetic foot ulcers (p = 0.534 > 0.05). Conclusions: There is no correlation between the neutrophil-to-lymphocyte ratio (NLR) and HbA1C levels in patients with diabetes mellitus and diabetic foot ulcers.
Differences In Hemoglobin Levels In Infected Patients Salmonella Typhi With Salmonella Paratyphi Based On Antibody Titer Laelin Hijriyani; Fihiruddin Fihiruddin; Iswari Pauzi; Ersandhi Resnhaleksmana
Jurnal Analis Medika Biosains (JAMBS) Vol. 13 No. 01 (2026): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

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Abstract

Salmonella typhi and Salmonella paratyphi cause the disease known as typhus abdominalis. The pathogenicity that distinguishes Salmonella typhi and Salmonella paratyphi comes from the virulent part of the bacterial capsule. Virulence factors are found on the surface of Salmonella typhi that are not found in Salmonella paratyphi. The toxic effect of Salmonella that suppresses the bone marrow and the presence of bleeding in the intestine can cause anemia, so a supporting examination is needed, one of which is the examination of Hemoglobin levels. The aimt of this study is knowing the difference of hemoglobin levels in patients infected with Salmonella typhi and Salmonella paratyphi based on antibody titer against H antigens: This study used Analytical Observational method with cross-sectional approach. Data obtained from typhoid fever patients from the examination of hemoglobin levels at Patut Patuh Patju Hospital as many as 96 people using secondary data.  "The mean hemoglobin level for Salmonella typhi, Salmonella paratyphi A, and Salmonella paratyphi B was 9.7 g/dL, 12.0 g/dL, and 12.6 g/dL, respectively. At antibody titers of 1/160 and 1/320, the mean hemoglobin levels for S. typhi were 10.5 g/dL and 9.2 g/dL; for S. paratyphi A, 12.0 g/dL and 11.8 g/dL; and for S. paratyphi B, 12.8 g/dL and 11.6 g/dL. According to the ANOVA test, there is a significant difference in the average hemoglobin levels among patients infected with S. typhi compared to those with S. paratyphi based on these antibody titers (< 0,001)