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Profil Klinikopatologi Meningioma di Instalasi Patologi Anatomi RSUD Dr. Saiful Anwar Malang Periode Tahun 2016-2020 Putri, Anggie Sasmita Kharisma; Diah Prabawati; Dewi, Rose Khasana; Angelina, Aina
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.3

Abstract

Background. The most common intracranial neoplasms worldwide is meningioma. It has been classified into three grades by World Health Organization (WHO) in which each grade has several histological variants. The prognosis of meningioma is affected by many factors including histopathological type of tumor, age, and gender. Objective. The aim of this study is to determine the frequency of meningioma based on histopathological type, age, and gender from 2016 to 2020 in Saiful Anwar General Hospital Malang. Methods. This study was a quantitative descriptive study and data was collected from medical records from 2016 to 2020 in Department of Anatomic Pathology, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital Malang. Histopathological type of meningioma, age, and gender were acquired. Results and Discussion. From 2016 to 2020, there were 96 eligible cases of meningioma. Ratio of men to women was 1:12.7. Meningioma was most commonly found in age group 41­50 years old (43.75%). The most common histopathological type of meningioma was meningotheliomatous meningioma (37.5%). The average of meningioma cases was 19 per year. In this study, there was an increase in incidence rate of meningioma in 2017, and decreased in 2020. It may happen because The government has a better referral system to provide health care, thus meningioma can be detected earlier. Conclusion. Frequency of meningioma is higher in women than men, and increases with age until 50 years, which then decreases. Meningotheliomatous meningioma is the most common histopathological type in this study.
Profil Klinikopatologi Meningioma di Instalasi Patologi Anatomi RSUD Dr. Saiful Anwar Malang Periode Tahun 2016-2020 Putri, Anggie Sasmita Kharisma; Retnani, Diah Prabawati; Dewi, Rose Khasana; Angelina, Aina; Diah Prabawati
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.3

Abstract

Background. The most common intracranial neoplasms worldwide is meningioma. It has been classified into three grades by World Health Organization (WHO) in which each grade has several histological variants. The prognosis of meningioma is affected by many factors including histopathological type of tumor, age, and gender. Objective. The aim of this study is to determine the frequency of meningioma based on histopathological type, age, and gender from 2016 to 2020 in Saiful Anwar General Hospital Malang. Methods. This study was a quantitative descriptive study and data was collected from medical records from 2016 to 2020 in Department of Anatomic Pathology, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital Malang. Histopathological type of meningioma, age, and gender were acquired. Results and Discussion. From 2016 to 2020, there were 96 eligible cases of meningioma. Ratio of men to women was 1:12.7. Meningioma was most commonly found in age group 41­50 years old (43.75%). The most common histopathological type of meningioma was meningotheliomatous meningioma (37.5%). The average of meningioma cases was 19 per year. In this study, there was an increase in incidence rate of meningioma in 2017, and decreased in 2020. It may happen because The government has a better referral system to provide health care, thus meningioma can be detected earlier. Conclusion. Frequency of meningioma is higher in women than men, and increases with age until 50 years, which then decreases. Meningotheliomatous meningioma is the most common histopathological type in this study.
DEDIFFERENTIATED LEIOMYOSARCOMA Putri, Anggie Sasmita Kharisma
Oceana Biomedicina Journal Vol 7 No 1 (2024): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v7i1.149

Abstract

ABSTRACTBACKGROUND : Leiomyosarcoma (LMS) is an aggressive soft tissue sarcoma that ranges from 7-10% of all cases of soft tissue sarcoma, usually occurring in adult and elderly patients.CASE REPORT : Patient Mr. M, male, 71 years old, construction worker, Tulungagung Regency. The patient has a main complaint, namely a lump under the right armpit, felt since 2 months before visiting dr. Iskak Tulungagung.DISCUSSION : Pleomorphic LMS or dedifferentiated LMS shows nonspecific and poorly differentiated pleomorphism. To make this diagnosis, the characteristic morphological features of classic LMS must be obtained, or the patient must have a prior history of LMS. On immunohistochemistry, approximately 50–75% of pleomorphic LMS are positive for at least one myogenic marker, although the smear is often weaker and more focal than in a typical area of leiomyosarcoma.CONCLUSION: Microscopically, the morphological appearance of dedifferentiated LMS can resemble the appearance of other high-grade sarcomas, so clinical, radiological, histopathological considerations and further examinations such as immunohistochemical smears are needed.
Edukasi Interaktif untuk Meningkatkan Literasi Kesehatan Reproduksi Remaja Cahya, Dini Aulia; Wahjuni, Endang Sri; Abidah , Hafshah Yasmina; Sasongko, Devi Purnamasari; Sugianto, Yenny Meilany; Putri, Anggie Sasmita Kharisma; Munasib, Abqariyatuzzahra
Journal of Community Development Vol. 6 No. 2 (2025): Desember
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/comdev.v6i2.1844

Abstract

Literasi kesehatan reproduksi remaja merupakan komponen penting dalam pembangunan kesehatan masyarakat karena berkaitan langsung dengan kemampuan remaja memahami perubahan biologis, psikososial, serta mengambil keputusan yang aman dan bertanggung jawab. Namun demikian, di banyak lingkungan sekolah, topik kesehatan reproduksi masih dipengaruhi oleh mitos, norma tabu, serta keterbatasan akses terhadap informasi yang tervalidasi secara ilmiah. Kondisi ini berpotensi memperkuat miskonsepsi, ketimpangan pengetahuan berbasis gender, serta meningkatkan kerentanan remaja terhadap berbagai risiko kesehatan. Kegiatan Pengabdian kepada Masyarakat (PKM) ini bertujuan untuk meningkatkan literasi kesehatan reproduksi remaja melalui pendekatan edukasi yang holistik, ilmiah, dan interaktif, sekaligus mendukung pencapaian Sustainable Development Goals (SDGs), khususnya SDG 3 (Good Health and Well-being) dan SDG 5 (Gender Equality). Kegiatan PKM dilaksanakan pada tanggal 30 Oktober 2025 dengan sasaran 60 siswa sekolah menengah pertama. Intervensi dilakukan melalui sesi edukasi interaktif yang mencakup pemahaman dasar anatomi dan fisiologi sistem reproduksi, kesehatan pubertas dan menstruasi, penguatan konsep kesehatan reproduksi yang setara gender, serta pelurusan mitos kesehatan reproduksi berbasis bukti ilmiah. Evaluasi kegiatan menggunakan desain pra–pasca dengan pre-test dan post-test masing- masing terdiri atas 10 soal pilihan ganda yang mencakup domain materi sepadan. Hasil evaluasi dianalisis dan disajikan secara deskriptif menggunakan kategori tingkat pemahaman. Sebelum intervensi, tingkat pemahaman siswa secara umum berada pada kategori rendah–sedang, terutama pada isu-isu yang berkaitan dengan pubertas, menstruasi, dan persepsi peran gender dalam kesehatan reproduksi. Setelah kegiatan edukasi, terjadi pergeseran kecenderungan tingkat pemahaman menjadi sedang–tinggi, disertai peningkatan kemampuan siswa dalam membedakan mitos dan fakta kesehatan reproduksi serta meningkatnya sikap saling menghormati antara siswa laki-laki dan perempuan. Kegiatan PKM ini menunjukkan bahwa edukasi kesehatan reproduksi yang dirancang secara holistik dan interaktif tidak hanya berpotensi meningkatkan literasi kesehatan remaja, tetapi juga berkontribusi pada upaya pengurangan kesenjangan gender dalam akses pengetahuan kesehatan. Dengan demikian, program ini relevan sebagai strategi penguatan peran sekolah dalam mendukung pencapaian SDG 3 dan SDG 5 secara berkelanjutan.