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All Journal Oceana Biomedicina Journal Jurnal Klinik dan Riset Kesehatan
Putri, Anggie Sasmita Kharisma
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Profil Klinikopatologi Meningioma di Instalasi Patologi Anatomi RSUD Dr. Saiful Anwar Malang Periode Tahun 2016-2020 Putri, Anggie Sasmita Kharisma; Diah Prabawati; Dewi, Rose Khasana; Angelina, Aina
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.3

Abstract

Background. The most common intracranial neoplasms worldwide is meningioma. It has been classified into three grades by World Health Organization (WHO) in which each grade has several histological variants. The prognosis of meningioma is affected by many factors including histopathological type of tumor, age, and gender. Objective. The aim of this study is to determine the frequency of meningioma based on histopathological type, age, and gender from 2016 to 2020 in Saiful Anwar General Hospital Malang. Methods. This study was a quantitative descriptive study and data was collected from medical records from 2016 to 2020 in Department of Anatomic Pathology, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital Malang. Histopathological type of meningioma, age, and gender were acquired. Results and Discussion. From 2016 to 2020, there were 96 eligible cases of meningioma. Ratio of men to women was 1:12.7. Meningioma was most commonly found in age group 41­50 years old (43.75%). The most common histopathological type of meningioma was meningotheliomatous meningioma (37.5%). The average of meningioma cases was 19 per year. In this study, there was an increase in incidence rate of meningioma in 2017, and decreased in 2020. It may happen because The government has a better referral system to provide health care, thus meningioma can be detected earlier. Conclusion. Frequency of meningioma is higher in women than men, and increases with age until 50 years, which then decreases. Meningotheliomatous meningioma is the most common histopathological type in this study.
Profil Klinikopatologi Meningioma di Instalasi Patologi Anatomi RSUD Dr. Saiful Anwar Malang Periode Tahun 2016-2020 Putri, Anggie Sasmita Kharisma; Retnani, Diah Prabawati; Dewi, Rose Khasana; Angelina, Aina; Diah Prabawati
Jurnal Klinik dan Riset Kesehatan Vol 2 No 3 (2023): Edisi Juni
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.02.3.3

Abstract

Background. The most common intracranial neoplasms worldwide is meningioma. It has been classified into three grades by World Health Organization (WHO) in which each grade has several histological variants. The prognosis of meningioma is affected by many factors including histopathological type of tumor, age, and gender. Objective. The aim of this study is to determine the frequency of meningioma based on histopathological type, age, and gender from 2016 to 2020 in Saiful Anwar General Hospital Malang. Methods. This study was a quantitative descriptive study and data was collected from medical records from 2016 to 2020 in Department of Anatomic Pathology, Medical Faculty, Brawijaya University, Saiful Anwar General Hospital Malang. Histopathological type of meningioma, age, and gender were acquired. Results and Discussion. From 2016 to 2020, there were 96 eligible cases of meningioma. Ratio of men to women was 1:12.7. Meningioma was most commonly found in age group 41­50 years old (43.75%). The most common histopathological type of meningioma was meningotheliomatous meningioma (37.5%). The average of meningioma cases was 19 per year. In this study, there was an increase in incidence rate of meningioma in 2017, and decreased in 2020. It may happen because The government has a better referral system to provide health care, thus meningioma can be detected earlier. Conclusion. Frequency of meningioma is higher in women than men, and increases with age until 50 years, which then decreases. Meningotheliomatous meningioma is the most common histopathological type in this study.
DEDIFFERENTIATED LEIOMYOSARCOMA Putri, Anggie Sasmita Kharisma
Oceana Biomedicina Journal Vol 7 No 1 (2024): Oceana Biomedicina Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/obj.v7i1.149

Abstract

ABSTRACTBACKGROUND : Leiomyosarcoma (LMS) is an aggressive soft tissue sarcoma that ranges from 7-10% of all cases of soft tissue sarcoma, usually occurring in adult and elderly patients.CASE REPORT : Patient Mr. M, male, 71 years old, construction worker, Tulungagung Regency. The patient has a main complaint, namely a lump under the right armpit, felt since 2 months before visiting dr. Iskak Tulungagung.DISCUSSION : Pleomorphic LMS or dedifferentiated LMS shows nonspecific and poorly differentiated pleomorphism. To make this diagnosis, the characteristic morphological features of classic LMS must be obtained, or the patient must have a prior history of LMS. On immunohistochemistry, approximately 50–75% of pleomorphic LMS are positive for at least one myogenic marker, although the smear is often weaker and more focal than in a typical area of leiomyosarcoma.CONCLUSION: Microscopically, the morphological appearance of dedifferentiated LMS can resemble the appearance of other high-grade sarcomas, so clinical, radiological, histopathological considerations and further examinations such as immunohistochemical smears are needed.
Co-Authors Aina Angelina Dewi, Rose Khasana Diah Prabawati Retnani, Diah Prabawati