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All Journal Usada Nusantara: Jurnal Kesehatan Tradisional Medical Laboratory Journal
Muhammad Azril Hardiman Mahulauw
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Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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Formulasi dan Uji Stabilitas Fisik Sediaan Foot Sanitizer Tropical Spray Ekstrak Etanol Daun Sirih (Piper betle L.) Yuni Widiastuti Hayoto; Aulia Debby Pelu; Muhammad Azril Hardiman Mahulauw
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 2 No. 1 (2024): Januari: USADA NUSANTARA
Publisher : Institut Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v2i1.617

Abstract

Foot sanitizer spray is an inventory containing 70%-95% etanol. The content of the active materials is alcohol that has the highest strength of bacteria. One of the plants empirically utilized by society as antiseptic antismell of feet is betel leaves (Piper betle L.). This study aimed to identify the chemical content of betel leaf (Piper betle L.), made fomulation of Foot Sanitizer Spray supplies from betel leaf etanol extract (Piper betle L.), and conducted a test evaluation inventory foot sanitizer spray as well as doing irritation tests against the probandus.This type of research was experimental research. The method used for this study includes: preparation of materials, sample extration (betel leaf), design fomulation of supply Foot Sanitizer Spray i.e. using three varied formulations with a 10% FI comparison, 15% FII, and FIII 20%, preparation of foot Sanitizer Spray and formulation evaluation test (physical stability test includes shape, color, smell), pH test and irritation test. The results of the research show the supply of Foot Sanitizer Spray from the esktrak etanol betel leaf (Piper betle L.) by using the concentration comparison of betel leaf extract, mentiones as FI 10%, FII 15% and FIII 20% have good shape, color, smell stability up to the storage of the seventh day, the result of the pH measurement is 4 to the seventh day, according to the standard of the topical availability pH based on the pH of the skin which is 4-6.5.As well as not eliciting irritation effect on the probandus.
Uji Efektivitas Antibakteri Dengan Perbedaan Konsentrasi Ekstrak Tinta Cumi-Cumi (Loligo Sp) dan Ekstrak Rumput Laut (Eucheuma cottonii) Pada Perairan Desa Buano Terhadap Bakteri Streptococcus mutans Penyebab Karies Gigi Lukman La Basy; Epi Dusra; Muhammad Azril Hardiman Mahulauw; Sahrir Sillehu; Siti Rahmawaty Tombalissa
Medical Laboratory Journal Vol. 1 No. 4 (2023): December : Medical Laboratory Journal
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/caloryjournal.v1i4.47

Abstract

Squid ink and seaweed have the potential to be utilized as medicines, one of which is as an antibacterial medicinal material. because it contains secondary metabolite compounds that can inhibit the growth of Streptococcus Mutans bacteria. This type of research is a laboratory experiment with the method used, namely maceration for phytochemical screening tests and agar diffusion for antibacterial effectiveness tests with concentrations used in squid ink (Loligo sp) namely 5%, 10%, 15% 20% and in seaweed (Eucheuma cottonii) 1%, 5%, 10%, 15%. The results of the research conducted on phytochemical screening tests contained secondary metabolite compounds in squid ink (Loligo sp) triterpenoids, steroids and seaweed (Eucheuma cottonii) alkaloids, flavonoids, hodroquinone phenols, and tannins. From the research conducted on the antibacterial effectiveness test of squid ink (Loligo sp) and seaweed (Eucheuma cottonii) extracts against Streptococcus mutans bacteria, namely in both samples have the effectiveness in inhibiting Streptococcus mutans bacteria, with a high inhibition of squid ink concentration of 20% by 20.5 mm, and in seaweed concentration of 15% by 23 mm. The analysis used is spss using two tests, namely the shapiro wilk test and the mann whitney test. The conclusion of the mann-whitney test results with a p-value = 0.663 indicates there is no significant difference between squid ink extract (Loligo sp) and seaweed extract (Eucheuma cottonii).
Co-Authors Aulia Debby Pelu Djulfikri Mewar Epi Dusra Lukman La Basy Sillehu, Sahrir Siti Rahmawaty Tombalissa Sri Wulandari Sahari Yuni Widiastuti Hayoto