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All Journal Jurnal Keperawatan Indonesia Timur (East Indonesian Nursing Journal) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Pengabdian Ilmu Kesehatan Jurnal Rumpun Ilmu Kesehatan Klinik: Jurnal Ilmiah Kedokteran dan Kesehatan Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Aulia Debby Pelu
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Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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TINGKAT PENGETAHUAN MEMPENGARUHI KEPATUHAN DIET HIPERTENSI PADA LANSIA DI DESA WAIMITAL KECAMATAN KAIRATU KABUPATEN SERAM BAGIAN BARAT Hikmawati Hikmawati; Nur Baharia Marasabessy; Aulia Debby Pelu
Jurnal Keperawatan Indonesia Timur (East Indonesian Nursing Journal) Vol 2 No 1 (2022): Januari - Juni 2022
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat Poltekkes Kemenkes Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32695/jkit.v2i1.280

Abstract

High blood pressure or hypertension is still a global and local health problem. One of the causes of hypertension is poor diet because they do not follow a hypertension diet properly. This can happen because of the patient's lack of knowledge about the diet itself. This study aims to determine the relationship between knowledge and dietary adherence to hypertension in the elderly in Waimital Village, Kairatu District, West Seram Regency. The research method used is descriptive analytic method with a cross sectional approach with a total sample of 40 respondents with hypertension. Sampling was done by total sampling technique. The data collection instrument used a questionnaire. The results showed that most of the respondents had a high level of knowledge (67.5%), and followed a hypertensive diet (62.5%). Statistical test results obtained p-value of 0.006 and p-value <0.05, which means that there is a relationship between the level of knowledge and adherence to a hypertension diet in the elderly. The level of respondent's knowledge was significantly related to hypertension diet compliance in the elderly with hypertension in Waitital Village, Kairatu District.
Formulasi dan Uji Stabilitas Fisik Sediaan Foot Sanitizer Tropical Spray Ekstrak Etanol Daun Sirih (Piper betle L.) Yuni Widiastuti Hayoto; Aulia Debby Pelu; Muhammad Azril Hardiman Mahulauw
USADA NUSANTARA : Jurnal Kesehatan Tradisional Vol. 2 No. 1 (2024): Januari: USADA NUSANTARA
Publisher : Institut Nalanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47861/usd.v2i1.617

Abstract

Foot sanitizer spray is an inventory containing 70%-95% etanol. The content of the active materials is alcohol that has the highest strength of bacteria. One of the plants empirically utilized by society as antiseptic antismell of feet is betel leaves (Piper betle L.). This study aimed to identify the chemical content of betel leaf (Piper betle L.), made fomulation of Foot Sanitizer Spray supplies from betel leaf etanol extract (Piper betle L.), and conducted a test evaluation inventory foot sanitizer spray as well as doing irritation tests against the probandus.This type of research was experimental research. The method used for this study includes: preparation of materials, sample extration (betel leaf), design fomulation of supply Foot Sanitizer Spray i.e. using three varied formulations with a 10% FI comparison, 15% FII, and FIII 20%, preparation of foot Sanitizer Spray and formulation evaluation test (physical stability test includes shape, color, smell), pH test and irritation test. The results of the research show the supply of Foot Sanitizer Spray from the esktrak etanol betel leaf (Piper betle L.) by using the concentration comparison of betel leaf extract, mentiones as FI 10%, FII 15% and FIII 20% have good shape, color, smell stability up to the storage of the seventh day, the result of the pH measurement is 4 to the seventh day, according to the standard of the topical availability pH based on the pH of the skin which is 4-6.5.As well as not eliciting irritation effect on the probandus.
Uji Farmakologi Antiinflamasi Ekstrak Etanol Daun Waru Laut (Thespesia Populnea (L.) Soland) Pada Tikus Putih (Rattus Norvegicus) Pia Batmomolin; Aulia Debby Pelu; Astin Buton
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 2 (2022): Juli: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i2.1276

Abstract

Waru laut (Thespesia populnea (L.) Soland) merupakan tanaman tepi pantai yang digunakan secara tradisional sebagai penurun bengkak. Tujuan dari penelitian ini adalah untuk mengetahui senyawa metabolit sekunder daun waru laut (Thespesia populnea (L.) Soland), untuk mengetahui potensi antiinflamasi ekstrak daun waru laut (Thespesia populnea (L.) Soland), dan efek dosis ekstrak daun waru laut (Thespesia populnea (L.) Soland) yang paling baik. Metode yang digunakan adalah eksperimental laboratorium dengan jenis postest control group design. Pada penelitian ini terdapat 5 kelompok hewan uji tikus putih diantaranya kelompok kontrol negatif (aquades), kontrol positif (Methylprednisolone), pelakuan 1 (ekstrak dosis 500 mg/kgBB), perlakuan 2 (ekstrak dosis 750 mg/kgBB), dan perlakuan 3 (ekstrak dosis 1000 mg/kgBB). Hasil dari penelitian ini adalah daun waru laut mengandung senyawa flavonoid, saponin, tanin. Kelompok Perlakuan 1 dan perlakuan 2 terjadi penurunan edema pada menit ke-120 yaitu 2,8 mm dari besar edema setelah 30 menit injeksi karagenin adalah pada kelompok perlakuan 1 sebesar 3,9 mm dan perlakuan 2 sebesar 3,7 mm. Sedangkan pada perlakuan 3 terjadi penurunan edema pada menit ke-120 yaitu 2,3 mm dari 3,95 mm edema setelah 30 menit injeksi karagenin. Pada dosis ekstrak daun waru laut memiliki potensi sebagai antiinflamasi dengan dosis yang paling baik adalah dosis 1000 mg/kgBB.
FORMULASI DAN EVALUASI SEDIAAN MASKER GEL PEEL-OFF EKSTRAK ETANOL DAUN KELOR (Moringa oleifera L.) DENGAN BASIS Na-CMC DAN CARBOPOL Aulia Debby Pelu; Jayanti Djarami; Irma Yanty Larajasi
Jurnal Pengabdian Ilmu Kesehatan Vol. 2 No. 1 (2022): Maret: Jurnal Pengabdian Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jpikes.v2i1.1309

Abstract

Moringa leaves (Moringa oleifera L.) contain flavonoid compounds, alkaloids, saponins, and tannins which are used as quality parameters of antioxidant preparations. Peel-off facial masks have several benefits, including being able to clean dirt on the face while removing dead skin cells, preventing skin damage caused by exposure to free radicals, such as acne and black spots, removing fine wrinkles due to premature aging, and moisturizing and nourishing the skin. The purpose of this study was to identify the chemical content of Moringa leaf (Moringa oleifera L.) and to formulate and evaluate the peel-off gel mask of the ethanol extract of Moringa leaf (Moringa oleifera L.) which was good and stable using a comparison of Na-CMC and Carbopol bases. . This research method is experimental which was carried out using Na-CMC base: Carbopol from three different formulations with a concentration ratio of F1 (3%: 0.1 %), F2 (4%: 1%), F3 (5%: 1.5 %), each formulation contains 3% Moringa leaf extract (Moringa oleifera L.). Evaluation of the peel-off gel mask preparation was carried out after 2 weeks of storage. The results showed an evaluation test of the peel-off gel mask preparation of Moringa leaf ethanol extract using Na-CMC and Carbopol bases on the homogeneity test of all homogeneous concentrations, the pH test showed that all concentrations of the preparation met the pH requirements, which ranged from 5-6, on the irritation test all the preparation did not cause redness and in the dry time test all preparations met the requirements, namely under 30 minutes. The conclusion of Moringa leaf ethanol extract using Na-CMC and Carbopol bases shows that it can be used as an alternative to cosmetics and can be used as a reference for use as natural cosmetics.
ANALISIS KADAR MERKURI (Hg) PADA IKAN DI KECAMATAN TELUK KAIELY KABUPATEN BURU MENGGUNAKAN METODE MERCURY ANALYZER Aulia Debby Pelu; Astuti Tuharea; Nur Hardianti.Walalayo
Jurnal Rumpun Ilmu Kesehatan Vol. 2 No. 1 (2022): Maret: Jurnal Rumpun Ilmu Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jrik.v2i1.1272

Abstract

Penambangan yang dilakukan di Indonesia adalah penambangan emas skala kecil, yang sering disebut dengan istilah PETI (Penambangan Emas Tanpa Izin). Kegitan ini biasanya menggunakan metode amalgasi dengan merkuri (Hg) untuk mendapatkan biji emas. .Merkuri (Hg) merupakan salah satu unsur yang paling beracun dari logam berat yang ada dan apabila terpapar pada konsentrasi yang tinggi maka mengakibatkan kerusakan otak secara permanen dan kerusakan ginjal. Di dalam air, logam merkuri dapat mengalami biotransformasi menjadi senyawa organik metil merkuri atau fenil merkuri akibat proses dekomposisi oleh bakteri. Senyawa organic tersebut diserap oleh jasa renik yang akan masuk dalam rantai makanan. Ini akhirnya tejadi akumulasi dan biomagnifikasi merkuri dalam tubuh biota laut seperti ikan, udang dan kerang yang pada akhirnya masuk kedalam tubuh manusia yang mengkonsumsinya. Penelitian ini menggunakan metode Mercury Analyzer yang dilakukan pada sampel ikan yang berbeda pada titik pengambilan yang berbeda pula untuk melihat ada tidaknya pencemaran merkuri di lingkungan pertambangan. Penelitian ini dilakukan di Kecamatan Teluk Kaiely Kabupaten Buru. Hasil penelitian ini menujukan bahwa 2 dari 3 sampel dinyatakan terkandung merkuri dengan kadar pada sampel di Kaiely ikan Kerong – Kerong (Terapon jarbua F.) sebesar 0,001 mg/L dan sampel di Kaki Air dengan ikan Pilchard Eropa (Sardina Pilchardus) sebesar 0,0003 mg/L. Sampel di Seith ikan Layang Biru (Decapterus macarellus) sebesar 0,00 mg/L atau tidak terdeteksi merkuri. Hasil ini menunjukan bahwa ikan masih layak dikonsumsi manusia karena dibawah baku mutu batas kandungan merkuri pada ikan yang dikonsumsi manusia yaitu sebesar 0,5 mg/kg
EFEK EKSTRAK ETANOL DAUN PALA (MYRISCITA FRAGRANS) TERHADAP GAMBARAN HISPATOLOGI AORTA TIKUS (RATTUS NORVEGICUS) DIABETES Pia Batmomolin; Aulia Debby Pelu; Rokia Latuamury
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 1 No. 1 (2022): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1107.188 KB) | DOI: 10.55606/jurrike.v1i1.477

Abstract

Daun pala (Myristica fragrans) gunakan masyarakat untuk mengobati bebrapa penyakit seperti nyeri. Bahan kimia yang terkandung dalam daun pala seperti saponin, polifenol, flavanoid, dan minyak atsiri. Untuk membuktikan aktivitas ekstrak etanol daun pala (myristica fragrans) terhadap aorta tikus (rattus norvegicus) diabetes. Penelitian ini merupakan jenis penelitian yang bersifat eksperimen laboratorium (laboratory experimen) secara in vivo menggunakan hewan coba tikus putih (rattus norvegicus) jantan galur wistar. Daun pala menggunakan pelarut etanol 96%. Diperoleh hasil maserasi sebanyak 300 g, dipekatkan dengan alat rotary evaporator diperoleh ekstrak kental sebanyak 42,673 g dengan %rendamen sebesar 14,23%. Didapatkan gambaran histologi terdapat lumen diameter yang lebih tipis dan lebih lebar dan sel busa pada bagian tunika intima dan media aorta tikus.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL RUMUT LAUT HIJAU (EUCHEUMA COTTONII) TERHADAP PERTUMBUHAN BAKTERI ” STAPHYLOCOCCUS AUREUS” Risman Tunny; Aulia Debby Pelu; Sultina Syari
JURNAL RISET RUMPUN ILMU KEDOKTERAN Vol. 1 No. 1 (2022): April :Jurnal Riset Rumpun Ilmu Kedokteran
Publisher : Pusat riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (969.101 KB) | DOI: 10.55606/jurrike.v1i1.478

Abstract

Rumput laut atau alga (euceuma cottanii) telah dimanfaatkan penduduk pantai di Indonesia untuk bahan pangan dan obat-obatan. Negara kepulauan, Indonesia dapat memanfaatkan sumber daya perairan dengan maksimal untuk di jadi suatu produk farmasi. ,mengandung senyawa biokimia sebagai metabolik sekunder salah satunya sebagai aktivitas antibakti, Penilitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak etanol pada Eucheuma Cottonii dapat menghambat bakteri Staphylococcus Aureus. Metode yang di gunakan yaitu difusi sumuran dan metode in nova. Pada penelitian ini dilakukan uji skrining fitokimia dan uji aktivitas antibakteri ekstrak rumput laut hijau (euceuma cottanii) dengan menggunakan pelarut etanol 70%. Ekstraksi rumput laut hijau (euceuma cottanii) dilakukan dengan menggunakan metode maserasi untuk mendapatkan ekstrak. Hasil uji skrining fitokimia ekstrak etanol 70% rumput laut hijau (euceuma cottanii) memiliki kandungan metabolit sekunder seperti : flavonoid dan steroid. Ekstrak rumput laut hijau (euceuma cottanii) mempunyai kemampuan menghambat pertumbuhan bakteri staphylococus aureus dengan diameter zona hambat terbesar yaitu pada kosentrasi 30% sebesar 19 mm, dan diameter yang terkecil pada kosentrasi 10% sebesar 15 mm. Maka dapat di Simpulkan bahwa Hasil uji skrining fitokimia ekstrak etanol 70% rumput laut hijau (euceuma cottanii) memiliki kandungan metabolit sekunder seperti : flavonoid dan steroid. Ekstrak rumput laut hijau (euceuma cottanii) mempunyai kemampuan menghambat pertumbuhan bakteri staphylococus aureus dengan diameter zona hambat terbesar yaitu pada kosentrasi 30% sebesar 19 mm, dan diameter yang terkecil pada kosentrasi 10% sebesar 15 mm.
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL KUMIS KUCING ( Orthosipon Aristatus )TERHADAP PERTUMBUHAN BAKTERI Staphyloccocus aureus DENGAN MENGGUNAKAN METODE DIFUSI Aulia Debby Pelu; Cut Bidara Panita Umar; Nadhira Fahreza Patimahu
Jurnal Ilmiah Kedokteran dan Kesehatan Vol 1 No 2 (2022): Mei: Jurnal Ilmiah Kedokteran dan Kesehatan
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (137.5 KB) | DOI: 10.55606/klinik.v1i2.1176

Abstract

Cat's whiskers leaf plant (Ortosiphon aristatues.) is one of the plants that is efficacious as a medicinal plant. The part of the cat's whiskers leaf plant is used, namely the leaves that contain saponin compounds, flavonoids, alkaloids and tannins. The purpose of this study was to determine the most effective inhibition produced by the ethanol extract of the leaves of the cat's whiskers (Ortosiphon aristatues.) against the growth of Staphyloccocus aureus bacteria. The benefit of this research is to increase knowledge about the antimicrobial potential of ethanol extract of cat whiskers (Ortosiphon arietatus) leaves against the growth of Staphyloccocus aureus bacteria. This research method uses the diffusion method for wells. The sample used was cat whiskers leaf extract with pure strain of Staphyloccocus aureus. Treatment with cat whiskers leaf extract, the results of the test of the inhibitory activity of the cat whiskers leaf extract showed an average difference at a concentration of 65% with a diameter of 22 mm, a concentration of 70% with a diameter of 25 mm, and a concentration of 75% with a diameter of 30 mm. Ethanol extract of cat whiskers leaves with a concentration of 65%, 70%, and 75% effectiveness in inhibiting the growth of Staphylococcus aureus bacteria. Based on observations, it was shown that the ethanolic extract of Kumis Kucing leaves gave the most effective inhibitory concentration at a concentration of 75% against Staphyloccocus aureus bacteria. with a diameter of 30 mm
Formulasi Dan Evaluasi Sediaan Salep Luka Bakar Basis Hidrokarbon Ekstrak Etanol Daun Katang-Katang (Ipomoea Pescaprae L.) Asal Desa Seith Tahun 2023 Nur’in Aihena; Aulia Debby Pelu; Sahril Sillehu
Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan Vol. 1 No. 4 (2023): Desember : Corona: Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebida
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/corona.v1i4.116

Abstract

Background: Ointment is a semisolid preparation used as a topical medicine, which has direct access to the skin tissues. Katang-katang is one of the medicinal plants traditionally used to treat various types of wounds. Objective: The aim of this study is to identify the secondary metabolite content of katang-katang leaves (Ipomoea pescaprae L.), create and evaluate a good and stable ointment formulation pharmaceutically, and test the irritation of the ointment for burn wounds using ethanol extract of katang-katang leaves (Ipomoea pescaprae L.). Method: The method used is experimental research, the ointment formulation is made using three formulations with different concentrations of active ingredients, with a ratio of FI 20%, FII 25%, and FIII 30%. Result: The results of the study indicate that katang-katang leaves contain flavonoids, tannins, and steroids. The study determined the formulation of a burn ointment from ethanol extract of katang-katang leaves (Ipomoea pescaprae L.). The organoleptic test results of FI, FII, and FIII showed good and stable color, odor, and shape, as well as homogeneity after one week of storage. The pH values measured were 7 for all formulations even after one week of storage. The spreading power of FI was (5.52 cm), FII was (5.88 cm), and FIII was (7.23 cm), which met the standards for good formulation. The irritation tests for all three formulas were categorized as safe. Conclusion: Based on the identification test results, the katang-katang leaves were found to contain flavonoids, tannins, and steroids. The evaluation test results for the three formulations using a hydrocarbon base showed that a good and stable burn ointment could be made from the ethanol extract of katang-katang leaves (Ipomoea pescaprae L.) without causing skin irritation.
UJI AKTIVITAS ANTIFUNGI EKSTRAK ANGGUR LAUT (Caulerpa sp.) ASAL PULAU GESER KABUPATEN SERAM BAGIAN TIMUR TERHADAP FUNGI Candida albicans Aulia Debby Pelu; Maryam Lihi; Moh. Nurul Iman Wokas
Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Vol. 2 No. 2 (2022): JULI : Jurnal Ilmu Kedokteran dan Kesehatan Indonesia
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikki.v2i2.1177

Abstract

Sea Grape (Caulerpa sp.) is a group of seaweed which is a macroalgae belonging to the Caulerpaceae family . Sea Grape very potential as a new antifungal drug because it contains secondary metabolites of saponins and flavonoids that can inhibit the growth of the fungus Candida albicans . The purpose of this study was to determine the content of secondary metabolites present in sea grapes and antifungal activity test of sea grapes (Caulerpa sp.) which was extracted using 70% ethanol as a solvent against the fungus Candida albicans. The antifungal activity was tested using the disc diffusion method with several concentrations of 5%, 10%, 25%, 50%, 85, 130%, 185%, and 250%, ketoconazole as a positive control and aquadest as a negative control. The results showed that the extraction of sea grapes contains secondary metabolites, namely: Saponins, Flavonoids, Tannins and Steroids capable of inhibiting the growth of the fungus Candida albicans, at a concentration of 25% with an inhibition zone diameter of 12.5 mm, 50% diameter of the inhibition zone 14.5 mm, 130% the diameter of the inhibition zone is 17.5 mm, 185% the diameter of the inhibition zone is 19 mm and 250% with the diameter of the inhibition zone is 22mm. The test results showed that the effective and very strong concentration of inhibiting the growth of Candida albicans was at a concentration of 250% with an inhibition zone of 22 mm.
Co-Authors Astin Buton Astuti Tuharea Cut Bidara Panita Umar Hikmawati Hikmawati Irma Yanty Larajasi Jayanti Djarami Marasabessy, Nur Baharia Maryam Lihi Moh. Nurul Iman Wokas Muhammad Azril Hardiman Mahulauw Nadhira Fahreza Patimahu Nur Hardianti.Walalayo Nur’in Aihena Pia Batmomolin Rokia Latuamury Sahril Sillehu Sultina Syari Tunny, Risman Yuni Widiastuti Hayoto